Elaeagnus angustifolia extract vs. quercetin in knee osteoarthritis.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Comparison of Elaeagnus angustifolia L. extract and quercetin on mouse model of knee osteoarthritis
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Mitra Heydari Nasrabadi, Malahat Parsivand, Narges Mohammadi, Nastaran Asghari Moghaddam
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Comparison of Elaeagnus angustifolia L. extract and quercetin on mouse model of knee osteoarthritis
Year: 2022 | Doi: 10.1016/j.jaim.2021.10.001
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Elaeagnus angustifolia extract vs. quercetin in knee osteoarthritis.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Flavonoid:
Flavonoids are a diverse group of plant compounds known for their antioxidant properties. They play a crucial role in plant health and are linked to various health benefits in humans, including anti-inflammatory and analgesic effects. Quercetin is a well-known flavonoid investigated in treating conditions like osteoarthritis.
2) Pain:
Pain is a significant symptom associated with various conditions, including osteoarthritis. The study of pain mechanisms is critical in understanding the pathophysiology of joint diseases. The investigation includes the evaluation of pain relief potential of treatments like drug therapies, herbal extracts, or lifestyle modifications in animal models.
3) Study (Studying):
A study refers to a systematic investigation aimed at discovering new insights or validating existing knowledge. In the context of osteoarthritis, studies focus on evaluating treatments or understanding disease mechanisms, highlighting the importance of experimental design, methodology, and rigorous analysis of results to draw valid conclusions.
4) Food:
Food represents the nutrients consumed by organisms for sustenance. In the context of health, diet plays a crucial role in managing diseases, including osteoarthritis. Foods rich in flavonoids and antioxidants could potentially reduce inflammation and improve joint health, underlining the significance of nutrition in chronic disease management.
5) Disease:
Disease refers to a pathological condition affecting normal bodily functions. Osteoarthritis is a degenerative disease impacting joint health, characterized by cartilage degradation and pain. Understanding the biological mechanisms of disease development is vital for developing effective treatments and improving patient outcomes through various therapeutic approaches.
6) Drug:
Drugs are substances used for medical treatment to alleviate symptoms or cure diseases. In osteoarthritis, several drugs, including non-steroidal anti-inflammatory drugs (NSAIDs) and novel plant-derived compounds, are investigated for their efficacy in reducing pain and inflammation, facilitating better quality of life for patients.
7) Inflammation:
Inflammation is a biological response to injury or harmful stimuli, often manifesting as swelling, pain, and redness. In osteoarthritis, inflammation contributes significantly to joint pain and tissue degradation. Understanding inflammatory pathways is essential for developing targeted therapies that mitigate these effects and promote joint health.
8) Activity:
Activity refers to the physiological actions performed by organisms or compounds. In pharmacological studies, assessing the activity of drugs or natural extracts is key to determining their effectiveness in treating conditions like osteoarthritis, where specific bioactivities can lead to beneficial health outcomes.
9) Writing:
Writing is the process of recording information in a structured format. In research, writing serves as a means to communicate findings effectively, allowing the dissemination of knowledge and facilitating collaboration among researchers and practitioners to advance understanding and treatment of diseases like osteoarthritis.
10) Animal:
Animals are often used in research to model human diseases, providing insights into mechanisms and potential therapies. In osteoarthritis studies, animal models, such as mice, are utilized to evaluate the efficacy of treatments, study disease progression, and assess both biological and behavioral responses to interventions.
11) Water:
Water is an essential solvent in biological processes and a key component of various experimental setups. In the preparation of herbal extracts or drug formulations, pure water is often used to dissolve compounds, allowing the extraction of bioactive ingredients that may exhibit therapeutic effects in treating diseases.
12) Table:
A table is a systematic arrangement of data, often used in research to present results clearly and concisely. In scientific studies, tables are crucial for summarizing quantitative data, such as the effects of treatments on various parameters, allowing for easy comparison and analysis of findings between groups.
13) Blood:
Blood is a body fluid critical for transporting nutrients, oxygen, and waste products. In biomedical research, analyzing blood samples for biomarkers, such as matrix metalloproteinases in osteoarthritis, helps assess the severity of disease, monitor treatment efficacy, and understand physiological changes linked to different interventions.
14) Ter:
Ther refers to therapy or therapeutic interventions aimed at treating diseases or alleviating symptoms. In differing contexts, various forms of therapy, including pharmacological, physical, and complementary therapies, are explored for their success in managing conditions such as osteoarthritis, emphasizing their importance in holistic health approaches.
15) Life:
Life encompasses the condition that distinguishes living organisms from inorganic matter. In medical research, understanding the impact of diseases on quality of life is essential. For patients with osteoarthritis, addressing symptoms and improving life quality through effective treatments highlights the broader implications of health on daily living.
16) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing diseases. It integrates various disciplines involving drug therapies, surgical interventions, and holistic approaches. In the context of osteoarthritis, the exploration of traditional and modern medical practices aims to enhance patient care and promote joint health.
17) Species:
Species refer to distinct groups of organisms that share common characteristics and can interbreed. In botanical and medicinal research, identifying plant species with therapeutic potential, such as Elaeagnus angustifolia, is essential for discovering natural remedies and understanding their pharmacological properties in treating diseases.
18) Powder:
Powder is a form of a substance consisting of finely ground particles. In pharmacological applications, many herbal extracts or drugs are prepared in powder form for easier consumption or further formulation. The preparation of powdered extracts is common in studies evaluating the efficacy of natural products in treatment regimens.
19) Hand:
Hand refers to the human appendage critical for manipulation and interaction with the environment. In medical research and rehabilitation, hand function and mobility are often assessed, especially in conditions such as osteoarthritis, where joint pain may significantly impact daily activities and overall quality of life.
20) Rheumatoid arthritis:
Rheumatoid arthritis is a chronic inflammatory autoimmune disorder affecting joints, leading to pain, swelling, and possible joint damage. Understanding its relationship with osteoarthritis is essential in developing treatments, as both conditions impact mobility and life quality, necessitating targeted therapies that alleviate symptoms and slow disease progression.
21) Surface:
Surface refers to the external layer of an object. In the context of osteoarthritis, the surface of articular cartilage is critical as its degradation contributes to the disease's symptoms. Research often focuses on surface properties of cartilage to evaluate disease progression and the effectiveness of treatments.
22) Alini:
Alini refers to a researcher associated with work on osteoarthritis or related fields. Researchers like Alini contribute to advancing understanding and treatment options for diseases, providing insight into biological mechanisms and therapeutic approaches through diligent studies aimed at enhancing patient care and treatment efficacy.
23) Death:
Death signifies the cessation of all biological functions that sustain an organism. In medical research, understanding death or mortality rates related to diseases such as osteoarthritis highlights the importance of developing effective treatments to prolong life expectancy and improve quality of life for affected patients.
24) Kubo:
Kubo is likely a reference to a researcher or study pertinent to osteoarthritis research. Individual researchers contribute to advancing the field through experimental studies, clinical trials, or reviews that provide critical insights into the pathophysiology and management strategies for improving outcomes in patients with joint diseases.
25) Peng:
Peng refers to a contributor in the field of biomedical research. The work of researchers named Peng may involve evaluating various therapeutic approaches, investigating disease mechanisms, and striving to unveil the complexities of conditions like osteoarthritis to aid in maximizing treatment efficacy and patient outcomes.
26) Crop:
Crop refers to cultivated plants harvested for consumption or other uses. In the context of medicinal plants, acknowledging the crop debate stresses the importance of sustainable cultivation and harvest of plants like Elaeagnus angustifolia, ensuring the availability of their therapeutic properties for research and potential treatments.
27) Road:
Road, in a metaphorical sense, signifies a pathway or direction taken in research. It may refer to a roadmap outlining steps towards understanding and treating diseases such as osteoarthritis, guiding scientists in exploring new treatments, methodologies, and theoretical approaches that align with current medical knowledge.
28) Post:
Post can refer to various meanings, including a recorded statement or article shared in the scientific community. In research contexts, posting results contributes to the discourse among professionals, elevating understanding of treatments like those for osteoarthritis and enabling engagement among researchers and practitioners in the field.
29) Veterinary medicine:
Veterinary medicine focuses on health and well-being of animals. In the context of osteoarthritis studies, applying veterinary principles helps in understanding how joint diseases are managed and treated in animals, which can translate knowledge into human medicine, offering insights into analogous conditions and therapy outcomes.
30) Peer review:
Peer review is a critical process in academic publishing where expert colleagues evaluate research for its validity, significance, and originality. This process ensures only high-quality studies, like those investigating osteoarthritis treatments, are published, facilitating the dissemination of reliable knowledge within the scientific community.
31) Observation:
Observation involves systematically noting and recording phenomena during research. In studies examining osteoarthritis, careful observation helps researchers document changes in subjects, impacts of interventions, or the progression of disease, serving as a foundation for data analysis and the development of effective treatment strategies.
32) Discussion:
Discussion refers to the section in academic papers, where authors analyze and interpret their findings. In osteoarthritis research, this section is vital for contextualizing results, comparing with existing literature, and proposing future research directions, enhancing understanding of the implications of treatments and disease mechanisms.
33) Himalaya (Hima-alaya):
Himalaya refers to a region in Asia known for its biodiversity, often associated with traditional medicine. Knowledge of species like Elaeagnus angustifolia, found within or near these mountains, highlights the importance of biodiversity in discovering therapeutic agents and understanding their roles in managing diseases, including osteoarthritis.
34) Quality:
Quality refers to the standard or grade of substances. In research, the quality of herbal extracts or pharmaceutical compounds is crucial for ensuring efficacy and safety. Evaluating the quality of ingredients used in treatments for osteoarthritis is vital for achieving desired health outcomes in clinical settings.
35) Mineral:
Minerals are naturally occurring inorganic substances essential for various physiological functions. In the context of osteoarthritis, minerals found in plants like Elaeagnus angustifolia may contribute to their therapeutic properties, supporting joint health and overall bodily functions, and highlighting the nutritional significance of these natural remedies.
36) Nature:
Nature refers to the inherent characteristics of organisms and ecosystems. In medicinal research, studying nature emphasizes the relationship between natural products and human health. Understanding the natural attributes of plants like Elaeagnus angustifolia can unveil their potential contributions to developing effective treatments for conditions like osteoarthritis.
37) Reason:
Reason refers to the rationale behind decisions or theories in scientific inquiries. Establishing a solid reason for research approaches, such as studying the effects of specific compounds on osteoarthritis, clarifies objectives, guides methodologies, and enhances the scientific discourse that drives the search for effective therapeutic solutions.
38) Mitra:
Mitra may refer to a researcher involved in studies concerning osteoarthritis or related topics. Researchers like Mitra play a crucial role in advancing knowledge through experimental design, exploration of treatment efficacy, and collaboration, aiming to enhance the understanding and management of chronic joint conditions.
39) Cina:
China is known for its rich history and diverse medicinal practices, including the use of herbal remedies. Its cultural emphasis on traditional medicine highlights the significance of substances like Elaeagnus angustifolia in treating ailments such as osteoarthritis, fostering interest in scientifically validating these practices within modern medicine.
40) King:
King may refer to a contributor or researcher whose work influences the understanding of diseases like osteoarthritis. Such individuals often provide insights through their research findings, emphasizing the collaborative nature of scientific inquiry aimed at improving the management of chronic conditions impacting health and quality of life.
41) Diet:
Diet encompasses the variety of foods and drinks consumed by individuals. In the context of health, diet is crucial for managing diseases like osteoarthritis, as certain foods can mitigate inflammation or promote joint health. Dietary studies assess the impact of nutrition on lifestyle-related health outcomes.
42) Pir:
Peer refers to individuals of equal standing or profession within a field. In scientific research, peers participate in the evaluation and critique of each other's work, ensuring quality and contributing to the collaborative environment essential for advancing understanding and treatment of diseases like osteoarthritis.
43) Male:
Male denotes biological sex and is often a variable in research concerning osteoarthritis. Examining differences in disease prevalence, symptoms, and treatment responses between males and females contributes to a comprehensive understanding of how sex influences disease dynamics and therapeutic outcomes in clinical settings.
Other Ayurveda Concepts:
Discover the significance of concepts within the article: ‘Elaeagnus angustifolia extract vs. quercetin in knee osteoarthritis.’. Further sources in the context of Ayurveda might help you critically compare this page with similair documents:
Statistical analysis, Antioxidant activity, Oxidative stress, Normal control, Osteoarthritis (OA), Matrix metalloproteinase-3, Histopathological analysis, Serum concentration, DPPH method, Elaeagnus angustifolia extract, Matrix metalloproteinase 13, Quercetin-treated group, Ibuprofen-treated group, Folin-Cicalteau method, Gavage administration, MIA model of OA, Iranian traditional medicinal system.