Effects of Striga orobanchioides on diabetes in rats.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Antidiabetic and antihyperlipidemic effects of crude fractions and isolated compound from Striga orobanchioides Benth on streptozotocin induced diabetic rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Sunayana Vikhe, Rahul Kunkulol, Dipak Raut
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Antidiabetic and antihyperlipidemic effects of crude fractions and isolated compound from Striga orobanchioides Benth on streptozotocin induced diabetic rats
Year: 2022 | Doi: 10.1016/j.jaim.2022.100618
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effects of Striga orobanchioides on diabetes in rats.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
In scientific research, a table organizes data systematically for easy interpretation. It allows readers to grasp complex information quickly, facilitating comparisons among different variables, such as biochemical parameters or measurements. Effective data presentation in tables enhances clarity and understanding, essential for drawing accurate conclusions in studies.
2) Activity:
In the context of pharmacological studies, 'activity' refers to the effect or response induced by a substance on biological systems. This can include antidiabetic effects, antihyperlipidemic properties, or enzyme inhibition. Assessing activity is crucial for evaluating the therapeutic potential of plant extracts or chemical compounds in medicine.
3) Study (Studying):
A study is a systematic investigation that seeks to provide insights or answers concerning specific hypotheses. In the referenced context, the study investigates the effects of the Ayurvedic plant 'Striga orobanchioides' on diabetes and lipid metabolism, contributing to the body of scientific knowledge and helping establish traditional medicines' relevance.
4) Animal:
Animal studies are vital in biomedical research, providing insights into biological processes that may not be achievable in vitro. They help researchers understand the pharmacokinetics and pharmacodynamics of substances, including the evaluation of antidiabetic and antihyperlipidemic activities of compounds derived from plants in a living organism.
5) Indian:
The term 'Indian' denotes origin or association with India, a country rich in biodiversity and traditional medicinal practices. Indian medicinal plants, such as 'Striga orobanchioides,' hold significant historical and cultural importance in treating diseases, emphasizing the intersection of traditional knowledge with contemporary biomedical research.
6) Drug:
A drug is a chemical substance used to treat, prevent, or diagnose illnesses. In this context, it refers not just to synthetic pharmaceutical compounds but also to bioactive plant derivatives that may offer therapeutic benefits, particularly in diseases like diabetes and hyperlipidemia, highlighting the importance of natural products.
7) Badami:
This refers to S. Badami, presumably a researcher or author involved in studies on plants and their pharmacological properties. Citing individual contributions acknowledges the collaborative nature of scientific research, and recognizing specific people fosters accountability and credit within the scientific community for their work and findings.
8) Blood:
Blood is vital in physiology, transporting nutrients, oxygen, and waste products. In diabetes research, understanding how various compounds affect blood glucose levels, insulin secretion, and lipid profiles is essential for developing effective treatments and strategies to manage or mitigate the impacts of diabetes and related conditions.
9) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. It includes conventional pharmaceuticals and traditional remedies derived from plants. The exploration of Ayurvedic medicine in this context showcases the importance of holistic approaches and integration of traditional knowledge with modern scientific validation in therapeutic efficacy.
10) Rules:
In scientific research, 'rules' refer to the established guidelines governing experimentation, analysis, and ethical considerations. Adhering to these rules ensures the validity and reliability of results, fostering trust in findings and ensuring compliance with ethical standards, especially concerning the treatment of animal subjects in research.
11) India:
India, a country with a rich heritage of traditional medicine, offers a vast biodiversity of natural resources. The significance of various Indian plants in providing medicinal benefits, alongside historical practices like Ayurveda, underlines the importance of integrating traditional knowledge with scientific exploration to foster innovative healthcare solutions.
12) Food:
Food plays a pivotal role in human health and is increasingly recognized for its medicinal properties. In discussions surrounding diets conducive to managing diabetes, understanding how food influences metabolic processes and the significance of dietary patterns can be crucial for developing holistic approaches to disease management.
13) Ayurveda (Ayus-veda):
Ayurveda, a traditional Indian system of medicine, emphasizes the use of natural substances for health and wellness. Its principles advocate for the application of natural remedies derived from plants to treat various ailments, including diabetes, underscoring the need for scientific exploration and validation of its efficacy.
14) Science (Scientific):
Science involves systematic knowledge acquisition and validation through empirical methods, contributing to human understanding of natural phenomena. In the context of medicinal studies, scientific research validates traditional practices, fostering a rigorous approach to exploring the therapeutic potential of various plants and their components.
15) Relative:
The term 'relative' in research often pertains to measurements or comparisons between groups. In pharmacological studies, it can denote how one treatment's effects or efficacy compares against another, which is essential to determine the significance and practical implications of findings within the context of medical treatment.
16) Pharmacological:
Pharmacological pertains to the study of the interactions between drugs and biological systems. This field explores how various substances affect physiological processes, which is crucial in understanding the therapeutic potential of compounds derived from plants, such as their antidiabetic or antihyperlipidemic properties.
17) Patil:
Patil likely refers to a contributing researcher or author involved in this study. Acknowledging individual researchers highlights collaboration and credit sharing in scientific findings, which is vital in maintaining scientific integrity and accountability in reporting research outcomes and contributions to the field.
18) Water:
Water is essential for life and biological functions. In pharmacological studies, understanding the role of adequate hydration in the health of animal models is crucial. It influences physiological responses, including metabolism and absorption of medications, affecting the efficacy of treatments studied for conditions like diabetes.
19) Nayar:
Nayar here refers to an author or contributor to the study, showcasing individual contributions within collaborative research. Recognizing specific researchers encourages accountability and promotes transparency in research findings, as well as facilitates the acknowledgment of efforts toward advancing scientific knowledge and public health.
20) Beta:
Beta may pertain to beta-cells in the pancreas, which are critical for insulin production. Understanding the function and pathology of beta-cells in diabetes research is fundamental for developing treatments aimed at enhancing or restoring their function, focusing on improving insulin secretion in diabetic patients.
21) Pose:
Pose, in a molecular docking context, refers to the orientation of a ligand (such as betulin) when binding to a target protein, such as an enzyme. Evaluating docking poses is vital to understanding the interaction dynamics between compounds and biological targets, which directs drug design and efficacy studies.
22) Antibiotic (Antibacterial):
Antibacterial relates to substances or actions that inhibit the growth of bacteria. In the context of medicinal plants, investigating their antibacterial properties supports the exploration of alternative treatments for infections, reinforcing the importance of traditional knowledge and natural products in developing new antimicrobial agents.
23) Inflammation:
Inflammation is a biological response to harmful stimuli like pathogens or tissue injury. Understanding its role in disease processes, such as diabetes, is crucial as chronic inflammation contributes to complications. Researching compounds that mitigate inflammation can enhance treatment strategies and improve patient outcomes in various conditions.
24) Observation:
Observation in research refers to the systematic collection of data and evidence regarding phenomena under study. In pharmacological contexts, careful observation during experiments is essential for identifying effects, side effects, and understanding the implications of treatments on biological systems, guiding the formulation of effective therapeutic strategies.
25) Toxicity:
Toxicity studies evaluate the adverse effects of substances, crucial for determining the safety and viability of compounds for therapeutic use. Understanding the toxicity of plant-derived compounds in preclinical models ensures that potential treatments minimize harm while providing beneficial effects, essential for public health and regulatory approval.
26) Delhi:
Delhi is the capital of India, known for its rich history and status as a center for education and healthcare. Scientific institutions in Delhi contribute significantly to medical research, enhancing understanding and innovation, impacting health policy and practice across the country and beyond.
27) Mast:
Mast cells are immune cells that play a role in allergic reactions and inflammation. Their study is crucial in understanding various pathologies, including allergies and autoimmune diseases. Investigating plant extracts for their effects on mast cells may lead to new treatments targeting allergic responses or inflammatory conditions.
28) New Delhi:
New Delhi, as the capital of India, serves as a hub for academic and scientific research, hosting numerous institutions focused on healthcare, medicine, and traditional practices like Ayurveda. Its status fosters collaborative efforts in research innovation, addressing health challenges and promoting public health initiatives.
29) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India known for its diversity in flora and traditional medicinal practices. The state's rich biodiversity provides opportunities for research into local plants’ pharmacological properties, enhancing our understanding of their therapeutic potential and integrating traditional knowledge with modern medical research.
30) Flavonoid:
Flavonoids are bioactive compounds found in many plants, known for their antioxidant and anti-inflammatory properties. They are critical in exploring natural therapies for managing health conditions, particularly in traditional medicine contexts, where their roles in disease prevention and treatment are increasingly examined in scientific studies.
31) Transformation (Transform, Transforming):
Transform refers to significant changes that alter the state or function of something. In biomedical research, the transformation of traditional medicine practices through scientific validation exemplifies how traditional knowledge can evolve, leading to the development of new therapeutic approaches based on empirical evidence and modern understanding.
32) Pravara:
Pravara likely refers to the Pravara Institute of Medical Sciences, an educational and research institution in India fostering advancements in medical sciences. Such institutions play a crucial role in exploring traditional medicines and their integration into contemporary healthcare practices, providing a platform for scientific inquiry and innovation.
33) Writing:
Writing encompasses the process of documenting research findings, contributing to the dissemination of knowledge. Clear and effective writing is essential in scientific communication, as it allows researchers to convey their discoveries and insights, facilitating knowledge sharing and fostering advancements in medicine and public health.
34) Channel:
In biological and medical research, 'channel' could refer to transport pathways for substances within an organism. Understanding various channels in physiology is essential for comprehending nutrient absorption, blood flow, and ion exchanges, informing how treatments impact metabolic processes and pathophysiological conditions.
35) Disease:
Disease refers to any pathological condition affecting an organism, leading to physiological abnormalities and impairments. Studying diseases such as diabetes emphasizes understanding their causes, mechanisms, and treatment strategies, guiding researchers in developing effective therapies and preventive measures, particularly using natural compounds or traditional medicines.
36) Species:
Species denotes the basic unit of biological classification, critical for biodiversity studies. Each plant species potentially harbors unique phytochemical compounds with therapeutic properties. Investigating diverse plant species enriches the understanding of natural remedies' pharmacological potentials, fostering innovations in drug discovery and development.
37) Pandita (Pandit):
Pandita may refer to a researcher or author contributing to the study. Recognizing individual authors in research fosters accountability and emphasizes collaborative efforts essential for advancing scientific knowledge, ensuring that contributions to the understanding of pharmacological properties and traditional medicine are adequately credited.
38) Humana:
Humana refers to the publishing company or platform that facilitates the dissemination of research findings. Such publishers play a vital role in ensuring that research is accessible to the scientific community and general public, enhancing collaboration and innovation in health and medicine fields.
39) Bombay:
Bombay, now Mumbai, is a significant urban center in India, associated with rich cultural and historical contexts. It hosts numerous educational and healthcare institutions that engage in research on local plants and traditional medicines, fostering the exploration of their pharmacological properties and potential healthcare applications.
40) Balaji:
Balaji may refer to a researcher or author involved in the studies described. Acknowledging individual contributions highlights the importance of collaborative research efforts, ensuring transparency and credit in the scientific community, which is fundamental in advancing research on medicinal plants and their potential benefits.
41) Gupta:
Gupta likely refers to one of the authors involved in the research, emphasizing individual contributions to collective scientific efforts. Recognizing diverse researchers is vital for accountability in scientific discourse, fostering collaboration that enriches pharmacological studies and the understanding of traditional medicine's role in healthcare.
42) Kumar:
Kumar represents a common surname, likely belonging to a researcher involved in the study. Citing researchers individually promotes transparency and accountability in the scientific process, recognizing their contributions to advancing knowledge regarding traditional medicines and their pharmacological properties in health sciences.
43) Sugar:
Sugar, primarily known as glucose, is a critical energy source for the body, but its regulation is paramount, particularly concerning diabetes. Understanding how different compounds, including those derived from plants, affect blood sugar levels is vital for developing therapeutic agents that manage diabetes effectively.
44) Field:
Field refers to a specific domain of study or research. In scientific contexts, various fields, such as pharmacology, botany, and biochemistry, intersect to explore the properties of natural substances. A multidisciplinary approach enhances understanding and drives innovation in medicine, particularly in traditional healing practices.
45) Pari:
Pari likely refers to a contributing researcher or author in the study, showcasing individual efforts within collaborative research. Acknowledging specific contributions highlights the importance of collaboration in advancing scientific knowledge, especially in the context of exploring traditional plants and their therapeutic potentials.
46) Diet:
Diet involves the types of food consumed by individuals, significantly impacting overall health and disease management. Nutritional studies explore how specific diets can influence conditions like diabetes, informing practices and policies aimed at promoting healthier lifestyles and integrating dietary considerations into medical treatments.
47) Line:
Line often relates to a sequence or connection in scientific discussions. It can refer to the lineage of research exploring certain topics or the continuation of knowledge from traditional medicine to modern practices, underscoring the evolution of dietary and medicinal practices in health science.
48) Ter:
Ther likely refers to therapy or therapeutic practices in medical contexts, particularly concerning the treatment of diseases. Understanding various therapeutic approaches, including those derived from traditional medicine, plays a crucial role in developing effective treatment modalities for managing conditions like diabetes or hyperlipidemia.
49) Life:
Life represents the biological processes and systems that characterize living organisms. In medical research, understanding life processes is crucial for identifying how diseases alter physiological functions, guiding the development of treatments that restore health and address underlying issues affecting life quality.
50) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is a widely used medicinal plant recognized for its anti-inflammatory and digestive properties. Its incorporation into research studies highlights the importance of exploring different plant species for their therapeutic potentials, especially in managing conditions like diabetes and gastrointestinal disorders.
51) Peer review:
Peer review is a critical process in academic publishing, ensuring research quality and integrity. Publications undergo rigorous evaluations by experts in the field before acceptance, fostering accuracy and reliability in scientific literature. This process upholds the credibility of research findings and advances knowledge in various disciplines.
52) Punica granatum:
Punica granatum, also known as pomegranate, is a fruit often studied for its health benefits, including antioxidant properties. Research into its medicinal qualities contributes to the broader exploration of natural products in treating various health conditions, emphasizing the importance of integrating traditional knowledge with scientific investigation.
53) Disfigurement:
Disfigurement refers to significant alterations or damage to physical form, often resulting from diseases or injuries. In medical research, understanding the underlying causes of disfigurement can inform treatment approaches, particularly in cases like diabetes where complications may lead to significant health impacts on quality of life.
54) Discussion:
Discussion in a research context involves interpreting results, comparing findings, and drawing conclusions from studies. It is a vital aspect of scientific writing, as it situates new research within existing literature, addresses implications, and suggests future research directions or applications of findings in real-world contexts.
55) Collecting:
Collecting refers to the systematic gathering of data or samples in research. In pharmacological studies, collecting plant materials or biological samples is crucial for analyzing compounds and understanding their pharmacological properties, emphasizing the meticulous nature of research that ensures accurate and reliable results.
56) Mountain:
Mountain landscapes often host diverse flora, presenting unique opportunities for discovering new medicinal plants. Research conducted in mountainous regions can reveal biodiversity, allowing scientists to explore the therapeutic potentials of plants found in these ecosystems, which may have adapted distinctively to their environment.
57) Commerce:
Commerce refers to the activities associated with the buying and selling of goods and services. In the context of medicinal plants, the trade of herbal products has become significant, highlighting the intersection between traditional medicine and commercial practices that can influence market trends and accessibility to natural remedies.
58) Euphoria:
Euphoria can refer to a plant genus known for various medicinal properties. Research involving 'Euphoria' species contributes to understanding the potential uses of these plants in traditional and modern medicine, highlighting the importance of botanical studies in discovering novel therapeutic agents.
59) Siddha:
Siddha is a traditional system of medicine from South India, emphasizing the use of natural remedies, herbs, and holistic treatments. Exploring Siddha practices contributes to the broader understanding of traditional medicinal systems and their potential integration into contemporary healthcare, enriching approaches to health and wellness.
60) Family:
Family refers to a taxonomic category in biological classification that groups species with shared characteristics. Understanding plant families is fundamental in pharmacology, as relatives often share similar active compounds, providing insights into the therapeutic potential of various species within a family.
61) Powder:
Powder in the context of herbal medicine often refers to the ground form of plant materials used in preparations. Utilizing powdered forms allows for easier consumption, dosage precision, and extraction of bioactive compounds, enhancing the efficacy and acceptability of traditional remedies in modern therapeutic practices.
62) Botany:
Botany is the scientific study of plants, encompassing their structure, growth, classification, and interactions with the environment. Understanding botany is critical for recognizing the pharmacological potential of various species, facilitating the development of new medicines and therapeutic strategies derived from natural plant products.
63) Ayus (Ayush):
Ayush refers to the traditional medicine systems in India encompassing Ayurveda, Yoga, Unani, Siddha, and Homeopathy. Recognizing Ayush reflects the growing interest in integrating these ancient practices with contemporary medicine, highlighting efforts to validate and promote natural remedies within global health paradigms.
64) Death:
Death, as a biological event, signifies the end of life and is often associated with various diseases. Understanding the causative factors and pathophysiological changes leading to death informs research on preventing and treating conditions, emphasizing the importance of effective therapeutic interventions in prolonging life.
65) Pune:
Pune, a city in Maharashtra, India, is known for its educational and research institutions. It serves as a hub for academic collaboration and the exploration of traditional medicines, facilitating studies aimed at evaluating the pharmacological potentials of indigenous plants and contributions to public health.
66) Accu (Accukuta):
Accu may refer to Accu-Chek, a brand offering blood glucose monitoring devices. Such devices play a crucial role in managing diabetes, enabling individuals to track their blood sugar levels effectively, empowering them to engage in informed health choices and enhancing treatment outcomes.
67) Post:
Post refers to the act of publishing or disseminating research findings for public and scholarly access. The act of posting research contributions ensures that findings reach a wider audience, facilitating dialogue, collaboration, and advancements in knowledge within the scientific community.
68) Pir:
Peer signifies the collaboration and review process where experts within a field evaluate each other's work. Engaging in peer review ensures the quality and integrity of scientific research, fosters constructive feedback, and promotes shared learning, which are essential for the progression of knowledge.
69) Male:
Male refers to the biological category typically associated with the production of sperm. In medical studies involving animals, understanding male physiology is critical for research design, particularly in studies investigating gender-specific responses to treatments, diseases, or biological phenomena.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Effects of Striga orobanchioides on diabetes in rats.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Ayurveda, Antioxidant properties, Lipid profile, In vitro, Antidiabetic activity, Molecular weight, Ethanolic extract, RT-PCR, Positive control group, Glycosylated hemoglobin, Experimental protocol, Normal control group, Antihyperlipidemic activity, Bioactive compound, In vivo, Streptozotocin (STZ), Spectroscopic analysis, Chromatographic Technique, Betulin, Molecular docking study, Pentacyclic triterpenoid.