Ayurvedic mix of Emblica and Curcuma improves insulin resistance in rats.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: An Ayurvedic formulation of Emblica officinalis and Curcuma longa alleviates insulin resistance in diabetic rats: Involvement of curcuminoids and polyphenolics
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Vandana Panda, Amol Deshmukh, Sneha Singh, Taasin Shah, Lal Hingorani
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Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: An Ayurvedic formulation of Emblica officinalis and Curcuma longa alleviates insulin resistance in diabetic rats: Involvement of curcuminoids and polyphenolics
Year: 2021 | Doi: 10.1016/j.jaim.2021.05.005
Copyright (license): CC BY-NC-ND 4.0
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Ayurvedic mix of Emblica and Curcuma improves insulin resistance in rats.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
Studying in this context emphasizes the necessity of rigorous research to understand diabetes and its management. This study represents an effort to explore traditional remedies scientifically, contributing to a more comprehensive approach to treating T2DM.
2) Table:
In scientific research, tables are essential for organizing and presenting data succinctly. They allow for easy comparison of results, such as the impact of various treatments on fasting blood glucose and insulin levels. Well-constructed tables enhance reader understanding and facilitate the communication of complex findings.
3) Homa:
The Homeostasis Model Assessment (HOMA) is a methodological tool used to estimate insulin resistance based on fasting blood glucose and insulin levels. It offers insight into the metabolic status of subjects and indicates the effectiveness of interventions, making it significant in diabetes research.
4) Animal:
Animal models, such as rats used in this study, are vital for understanding the pathophysiology of diseases like diabetes. They allow researchers to explore disease mechanisms and therapeutic effects before applying findings to human patients, ensuring safety and efficacy in potential treatments.
5) Diet:
The high-fat diet used in the research creates a condition to induce insulin resistance in rats. This dietary manipulation is crucial in replicating the human condition of type 2 diabetes, thereby allowing for a more accurate assessment of the intervention's potential effects.
6) Drug:
Drugs like metformin are standard treatments for type 2 diabetes. They help manage insulin resistance and fasting blood glucose levels. The study contrasts herbal treatments with established pharmaceutical therapies, exploring alternative treatment options that might provide additional benefits or fewer side effects.
7) Blood:
Blood glucose levels are a critical parameter in assessing diabetes and insulin resistance. Regular monitoring of fasting blood glucose in the study allows for the evaluation of treatment efficacy and the understanding of metabolic changes in response to dietary or pharmacological interventions.
8) Water:
Water is essential for maintaining hydration and supporting metabolic processes in living organisms, including experimental animals. The provision of water ad libitum ensures that the rats in the study remain hydrated, which is vital for accurate physiological assessments and experimental integrity.
9) Emblica officinalis:
Also known as Amla, this fruit is noted for its potential health benefits, including anti-diabetic effects. The study evaluates Emblica officinalis as a component of EmbliQur, investigating its role in alleviating insulin resistance and improving glycemic control.
10) Activity:
Activity refers to the biological effects of treatments administered in the study. The measurement of therapeutic activity, particularly in lowering insulin resistance and blood sugar levels, indicates the efficacy of herbal formulations in managing diabetes compared to traditional pharmaceuticals.
11) Disease:
Type 2 diabetes is categorized as a chronic disease involving insulin resistance, leading to various health complications. The study aims to explore alternative treatment modalities to manage this burgeoning public health challenge, emphasizing the need for effective interventions.
12) India:
India is significant in the context of this study as the origin of Ayurvedic medicine, including the herbal formulation being researched (EmbliQur). The cultural and medical practices rooted in India provide a foundation for investigating traditional remedies in modern healthcare.
13) Calculation:
Mathematical calculations, particularly those involving insulin sensitivity indices, play a pivotal role in analyzing and interpreting study results. The precision of these calculations is essential for validating the effectiveness of treatments in reducing insulin resistance and managing diabetes.
14) Alleviation:
Alleviation refers to the reduction of symptoms or severity of a condition. The study focuses on the alleviation of insulin resistance through the administration of EmbliQur, highlighting its potential as a therapeutic option in managing type 2 diabetes.
15) Amla:
Amla, or Emblica officinalis, is a prominent fruit in Ayurvedic medicine. It's recognized for its antioxidant and anti-diabetic properties. The study specifically investigates its role in the formulation EmbliQur, contributing valuable insights into natural remedies for managing diabetes.
16) Curcuma longa:
Known as turmeric, Curcuma longa is valued for its anti-inflammatory and antioxidant properties. The study explores its contribution to EmbliQur, emphasizing the potential benefits of curcumin in regulating blood sugar and enhancing insulin sensitivity.
17) Turmeric:
Turmeric, the rhizome of Curcuma longa, is widely studied for its health benefits, particularly in metabolic disorders. In the context of this research, turmeric's active components like curcumin could play a significant role in improving insulin sensitivity and managing diabetes.
18) Powder:
In the study, powders derived from plants like Amla and turmeric are utilized to prepare the herbal formulation EmbliQur. The form of the ingredients is crucial for ensuring consistent dosage and maximizing the therapeutic effects in the experimental model.
19) Beta:
Beta refers to pancreatic beta cells, which are crucial for insulin production. Impairment of these cells is a hallmark of diabetes. The study indirectly relates to beta cell function by assessing the overall insulin response within the diabetic model used.
20) Knowledge:
Knowledge in the context of diabetes management emphasizes the need to understand the disease mechanisms and effective treatments. The study contributes to this body of knowledge by evaluating a traditional herbal formulation against established drug interventions.
21) Composite:
Composite refers to combining multiple elements, such as data from various assessments. In the study, composite indices like Matsuda are utilized to provide a comprehensive understanding of insulin sensitivity, enhancing the robustness of the results obtained from the experimental analysis.
22) Medicine:
The discussion around medicine in this study encompasses both traditional and modern therapeutic approaches to diabetes. Investigating the efficacy of an Ayurvedic formulation offers a holistic perspective on treatment options, enriching the field of diabetes research.
23) Thomas:
Thomas refers to a specific researcher or contributor in the larger context of diabetic research. Individuals like Dr. Thomas contribute to the understanding of insulin dynamics, offering insights that may enhance new therapeutic strategies outlined in this study.
24) Nature:
The term nature signifies the importance of understanding and utilizing natural products for therapeutic purposes. The study's exploration of herbal formulations showcases the potential of natural remedies in modern medicine, particularly in addressing chronic conditions like diabetes.
25) Saxena (Sakshena, Saksena):
Saxena likely refers to a researcher or author associated with diabetes studies or the evaluation of herbal medicines. The presence of recognized contributors enriches the credibility and depth of the research findings presented in this study.
26) Pandita (Pandit):
Pandit, as a contributing individual to diabetes research, adds to the academic rigor and scholarly discourse on herbal treatments for chronic diseases, particularly those relating to insulin resistance and blood sugar management as discussed in this study.
27) Patel:
Patel may refer to a researcher involved in the study that emphasizes the significance of scientific inquiry into herbal remedies for diabetes. The collaboration of authors reflects diverse expertise that bolsters the study's findings.
28) Chang:
Chang refers to an author or researcher whose contributions may seminally influence diabetic research. The collective efforts of diverse researchers lead to richer insights into managing diabetes through both modern and traditional medicine.
29) Nambi:
Nambi likely refers to a researcher or contributor noted for advancements in diabetes treatment. Their insights contribute to better understanding interventions that may improve insulin sensitivity, pivotal in managing type 2 diabetes.
30) Rules:
Rules in medical research involve ethical and methodological guidelines steering studies' design and implementation. Adhering to established rules ensures the validity and reliability of findings, particularly in evaluating treatments for diabetes.
31) Death:
Death, in the context of diabetes research, highlights the critical health risks associated with the disease, including complications like cardiovascular disease. This study's exploration of potential treatments aims to reduce such risks and improve patient outcomes.
32) Peer review:
Peer review is a critical validation process in scientific research that enhances study credibility by ensuring that findings meet rigorous standards of quality. The results of this study are likely reviewed to ensure they contribute meaningfully to the field.
33) Measurement:
Measurement is essential in research for quantifying variables such as blood glucose and insulin levels. Accurate measurement allows researchers to evaluate treatment efficacy and determine the biological effects of interventions in the context of the study.
34) Observation:
Observation refers to the careful monitoring of study subjects to assess treatment effects. Systematic observation is crucial for gathering reliable data and making informed conclusions about the efficacy of interventions tested in the study.
35) Discussion:
Discussion sections in scientific papers summarize findings and contextualize the results within broader research. They help interpret the implications of the study, exploring how the findings advance understanding of diabetes treatment and management strategies.
36) Collecting:
Collecting data involves systematically gathering information throughout the research process, ensuring comprehensive insights into treatment efficacy. In the study, collecting blood samples at various intervals provides critical data to evaluate the effects of interventions on insulin resistance.
37) Antibiotic (Antibacterial):
Streptozotocin, used to induce diabetes in rats, is categorized as an antibiotic. Its mechanism affects pancreatic beta cells. Understanding its role and effects is essential in assessing the model's validity for studying diabetes and potential treatments.
38) Suffering:
Suffering often describes the impact of chronic diseases like diabetes on individuals' quality of life. The study aims to find therapeutic options that can alleviate this suffering effectively, reflecting a broader goal of improving patient outcomes.
39) Toxicity:
Toxicity refers to the potential harmful effects of substances, particularly when evaluating drug safety. In this study, the lack of significant toxicity at specified doses of EmbliQur underscores the safety of the herbal formulation in managing diabetes.
40) Cancer:
Streptozotocin, although primarily used to induce diabetes, is known as an anti-cancer agent. Its relevance extends beyond diabetes, and understanding its multifaceted applications underscores the complexity of drug interactions in biochemical pathways.
41) Indian:
Indian refers to the origin of the herbal formulation being studied, which is rooted in traditional medicine. Such cultural contexts are crucial for understanding the historical significance and potential efficacy of natural remedies for diabetes.
42) Indigo:
Indigo, mentioned in the context of scientific measurements involving colored indicators, plays a role in chemical analysis methods. It is pertinent when discussing quantitative assessment techniques that validate the findings in pharmacological studies.
43) Gold (Golden):
The term golden can symbolize the ideal or optimal conditions sought in scientific research. It may refer to achieving the best outcomes in treatment efficacies that the study aims to elucidate in addressing diabetes.
44) House:
House signifies a controlled environment where animals were kept during the study, ensuring well-being and ethical treatment. Proper housing of experimental subjects is crucial for the validity of research outcomes and the interpretation of results.
45) Amol:
Amol refers to an author or contributor in the study, emphasizing the collaborative nature of scientific research. Each contributor's expertise enriches the study's findings and reinforces the collective understanding of diabetes management.
46) Cage:
Cage refers to the controlled environment in which experimental animals are housed. The conditions of the cage ensure humane treatment and are vital for maintaining the physiological health of subjects throughout the research.
47) Hand:
Hand indicates the manual involvement of researchers in administering treatments and conducting experiments. This hands-on approach is essential for ensuring accuracy and consistency in experimental procedures and data collection.
48) Milk:
Milk, included in the diet recipe, might contribute to understanding the nutritional aspects of the high-fat diet used in the study. Recognizing all components of the diet used to induce diabetes is crucial for interpreting results accurately.
49) Post:
Post often refers to procedures conducted after a certain event or treatment. In this research, it can describe the follow-up assessments after administering treatments to evaluate their impact over time.
50) Pir:
Peer denotes colleagues or experts in the field who assess, critique, and validate research before publication. Engaging in peer review ensures the quality and integrity of research findings that contribute to scientific literature.
51) Pur:
Poor indicates suboptimal results or conditions observed during research. The study might emphasize how certain treatments were recognized as poor in efficacy compared to others, guiding future directions in researching diabetes interventions.
52) Male:
Male specifies the gender of the Sprague Dawley rats used in the study, which is essential for considerations of hormonal differences and responses to interventions in diabetes research. Understanding gender differences can influence treatment outcomes.
Other Ayurveda Concepts:
Discover the significance of concepts within the article: ‘Ayurvedic mix of Emblica and Curcuma improves insulin resistance in rats.’. Further sources in the context of Ayurveda might help you critically compare this page with similair documents:
Statistical analysis, Control group, Insulin resistance, Type 2 Diabetes Mellitus, Animal Ethics Committee, Oral glucose tolerance test, Tannin, Ayurvedic herbal formulation, Fasting blood glucose level, Streptozotocin, High-fat diet, Curcuminoids, Gallic acid, Anthropometric Measures, Diabetes induction, Homeostasis model assessment of insulin resistance, Quantitative insulin sensitivity check index.