A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Harish Gopinath, Murugesh Shivashankar
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Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats
Year: 2021 | Doi: 10.1016/j.jaim.2021.03.004
Copyright (license): CC BY-NC-ND 4.0
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
In the context of scientific research, a 'table' refers to a structured arrangement of data, often presented in rows and columns. Tables facilitate easy comparison and analysis of different variables, making it simpler to interpret results and draw conclusions. They are essential for displaying quantitative data effectively.
2) Toxicity:
Toxicity refers to the degree to which a substance can cause harm to living organisms. In pharmacological studies, assessing toxicity is crucial to ensure that medications or treatments do not have adverse effects. Understanding toxicity helps researchers evaluate safety and efficacy, guiding dosage and treatment protocols.
3) Bhasma (Bhasman):
Bhasma is an important term in Ayurveda, indicating a type of calcined medicine made from minerals or herbs. Its preparation involves specific processes that render it safe and bioavailable for therapeutic use. Bhasma is recognized for its medicinal properties and is often used in Ayurvedic formulations to treat various ailments.
4) Blood:
Blood is a vital fluid in the human body that carries oxygen and nutrients to cells while removing carbon dioxide and waste products. In medical studies, measuring blood parameters such as glucose levels, cholesterol, and other biomarkers is crucial for diagnosing and monitoring conditions like diabetes or cardiovascular diseases.
5) Disease:
A disease is a pathological condition characterized by a disturbance in the structure or function of a biological system. Understanding diseases involves studying their causes, symptoms, and potential treatments. Researching diseases, particularly chronic illnesses like diabetes, is essential for developing effective medical interventions and improving patient outcomes.
6) Animal:
In biomedical research, 'animal' refers to non-human creatures used for testing and experimentation. Animal studies help scientists understand biological processes, test drug efficacy, and assess safety. Ethical considerations are paramount, and research must follow guidelines to ensure animal welfare during experiments that contribute to human health advancements.
7) Study (Studying):
A 'study' is a systematic investigation to establish facts or principles. In research, studies are designed to test hypotheses, analyze data, and derive conclusions. Various methodologies, including observational, experimental, and clinical trials, are employed to provide evidence-based results that advance knowledge in fields like medicine and health sciences.
8) Honey:
Honey is a natural substance produced by bees, valued for its sweetness and medicinal properties. In traditional medicine, including Ayurveda, honey is often used as a medium for administering herbal remedies. Its properties include antioxidant effects and promoting healing, making it a popular ingredient in health formulations.
9) Drug:
A drug is a chemical substance used for medical treatment, prevention, or diagnosis. Understanding a drug's pharmacology includes its effects, mechanisms of action, and potential side effects. Researching drugs is essential in developing effective therapies for diseases and improving public health outcomes through evidence-based interventions.
10) Relative:
In scientific research, 'relative' often refers to measurements or parameters compared to a standard or control. It is crucial for interpreting data, particularly in toxicity studies where the effects of a substance may be assessed relative to control groups, enabling clear distinctions about safety and efficacy.
11) India:
India is known for its rich tradition in Ayurvedic medicine, which utilizes natural substances and holistic approaches for health. Research and studies conducted in India often focus on traditional remedies, such as bhasma, highlighting the intersection of ancient practices and modern scientific validation for improving health outcomes.
12) Male:
In scientific studies, 'male' distinguishes male subjects, typically used in research contexts to investigate gender-specific responses to treatments or diseases. Understanding differences in biological responses based on sex is crucial for developing gender-appropriate medical therapies and ensuring comprehensive health care.
13) Substance:
A substance refers to a particular type of matter with specific properties, often studied to determine its safety, efficacy, and interactions in pharmacology. Researching substances, including drugs and their formulations, helps to analyze their effects on biological systems, contributing to advancements in healthcare and therapeutics.
14) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. It involves various modalities, including pharmacological, surgical, and therapeutic interventions. The study of medicine is essential for advancing healthcare practices and improving patient outcomes through evidence-based approaches and clinical research.
15) Activity:
In scientific research, 'activity' commonly refers to the effectiveness or physiological response elicited by a drug or treatment. For example, in pharmacology, assessing the activity of a compound against diseases helps determine its therapeutic potential and informs dosage and treatment protocols for clinical use.
16) Rules:
In research contexts, 'rules' refer to the established guidelines and protocols that govern study design, ethical considerations, data collection, and analysis. Adhering to these rules is critical to ensure the validity and reliability of research findings, as well as protecting participant rights and welfare.
17) Observation:
Observation refers to the process of monitoring and recording data during research. It is a key method used in studies to gather empirical evidence about subjects' responses, behaviors, or outcomes. Accurate observations are vital for drawing conclusions and validating hypotheses in scientific research.
18) Indian:
The term 'Indian' denotes a cultural and geographical identity, particularly related to practices, traditions, and medicinal systems native to India. This is especially significant in contexts such as Ayurveda, which incorporates extensive knowledge of herbs and minerals, influencing contemporary studies of traditional medicine for therapeutic benefits.
19) Science (Scientific):
Science encompasses the systematic study of the natural world through observation, experimentation, and analysis. It is foundational for understanding complex systems, developing new technologies, and informing public policy. Science is central to driving advancements in healthcare and improving overall quality of life.
20) Water:
Water is a fundamental solvent and medium in biological systems, essential for life and various physiological processes. In research, the quality of water used in experiments, such as diluting substances or preparing solutions, is critical to obtaining accurate and reliable results in scientific investigations.
21) Mica:
Mica is a mineral often used in Ayurvedic preparations, including bhasma due to its unique properties. Mica undergoes specific processing to enhance its therapeutic effects in traditional medicine. Understanding its role contributes to the formulation and application of Ayurvedic remedies in modern healthcare practices.
22) Jamatakni (Jamat-akni):
Jamadagni refers to a notable author or contributor in the field of Ayurveda. Recognizing individuals like Jamadagni emphasizes the historical context and rich tradition behind Ayurvedic practices, highlighting their significance in medicinal formulations and their relevance in contemporary health challenges.
23) Abhraka:
Abhraka is a specific type of bhasma made from mica, known for its herbal and mineral therapeutic properties. Its use in Ayurvedic medicine reflects traditional approaches to health and wellness, aiming to improve physical ailments, particularly those related to metabolism and energy balance.
24) Shastra (Sastra):
Sastra denotes a body of knowledge or scripture in the context of Ayurveda. This highlights the importance of traditional texts in guiding the preparation and application of medicinal treatments based on longstanding practices, reflecting the combination of empirical observations and scriptural wisdom in holistic health.
25) Medium:
In scientific research, 'medium' often refers to the substance or environment in which reactions occur or biological samples are cultured. Identifying the appropriate medium is critical for ensuring optimal conditions that facilitate accurate observations and reliable results in experiments, especially in pharmacological contexts.
26) Aruna:
Aruna is a name associated with researchers or contributors in Ayurvedic studies, potentially indicating the relevance of individual contributions to the broader field. Acknowledging the work of individuals named Aruna may shine a light on significant findings and advancements in traditional medicine research.
27) Sign:
In research, a 'sign' refers to an observable phenomenon or indicator related to a condition or treatment effect. Identifying signs during studies enables researchers to monitor outcomes and gauge the effectiveness of interventions, crucial for developing evidence-based therapeutic approaches.
28) Mineral:
Minerals are inorganic substances essential for various physiological functions in the human body. In traditional medicine, minerals like those in bhasma are utilized for their healing properties. Understanding the role of minerals helps bridge the gap between traditional practices and modern scientific insights regarding health.
29) Nature:
Nature encompasses the inherent characteristics and behaviors of living organisms and their environments. In medicinal research, studying natural compounds informs understanding of their therapeutic effects and interactions, essential for developing drugs that leverage nature's diverse resources to treat various health conditions.
30) Cage:
In laboratory settings, 'cage' refers to the environment in which experimental animals, such as rats, are housed during studies. Proper housing is crucial for ensuring the welfare of animals, influencing their health and behavior, which, in turn, affects research outcomes.
31) Life:
Life indicates the biological state of living organisms and encompasses complex systems and interactions. In research, understanding life processes is fundamental for medical studies aimed at improving health and addressing diseases, guiding treatments that align with the biological functions of organisms.
32) Abhrakabhasma (Abhraka-bhasma):
Abhraka-bhasma is a specific Ayurvedic formulation derived from mica, historically significant in traditional Indian medicine. Its therapeutic uses and methods of preparation represent the integration of mineral-based treatments into holistic healthcare practices, underscoring the relevance and potential of such formulations in contemporary medicine.
33) Amritikarana (Amrtikarana, Amriti-karana):
Amritikarana is a term related to the process of revitalization or rejuvenation in Ayurvedic practice. Understanding this concept emphasizes the holistic approach of Ayurveda in promoting health and wellness, particularly in the context of treatments designed to enhance vitality and overall well-being.
34) Shilajatvadi (Silajatvadi, Shilajatu-adi):
Shilajatvadi refers to an Ayurvedic formulation involving the herb Shilajit, known for its potent medicinal properties. Studying such formulations reflects the integration of various botanical ingredients aimed at enhancing health, drawing on the wisdom of traditional practices in the modern therapeutic landscape.
35) Accumulation (Accumulating, Accumulate):
Accumulation in a biological context refers to the buildup of substances in living organisms, which can affect health and metabolic functions. Researching accumulation is critical to understanding toxicology, pharmacokinetics, and the long-term effects of substances, guiding safe practices in medicine and healthcare.
36) Carpenter:
Carpenter is likely a reference to a contributing researcher or author. Recognizing contributions from individuals like Carpenter highlights the collaborative nature of scientific research in fields such as pharmacology and toxicology, underscoring the importance of interdisciplinary approaches in advancing knowledge and understanding.
37) Flavonoid:
Flavonoids are a group of plant metabolites with antioxidant properties, playing a role in human health. They are studied for their potential to modulate biological processes and contribute to the prevention of diseases such as diabetes. Investigating flavonoids enriches the understanding of dietary impacts on health.
38) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine originating from India, emphasizing balance in physical, mental, and spiritual aspects of health. Its holistic approaches, including herbal and mineral treatments, provide a framework for natural healing, contributing to modern discussions on integrated healthcare and wellness.
39) Mahadeva (Maha-deva):
Mahadeva could refer to prominent figures in the context of Ayurvedic studies or implications in research. Acknowledging such figures emphasizes the cultural and historical narratives that inform and guide traditional practices, influencing methodologies and perspectives in modern scientific investigations.
40) Bandara (Bamdara):
Bandara may refer to a researcher or contributor notable in Ayurvedic medicine or related studies. Recognizing individuals such as Bandara brings to light the importance of specific contributions and insights in refining and validating traditional practices within contemporary health paradigms.
41) Pranali:
Pranali may denote a contributor or researcher involved in Ayurvedic studies. Acknowledging such individuals highlights the collaborative efforts driving advancements in traditional medicine, demonstrating the community's role in shaping and evolving practices essential for addressing health challenges.
42) Samtosha (Samtosa, Santosa, Santosha, Santosh):
Santosh could refer to a researcher or practitioner in the field of Ayurvedic medicine. Acknowledging contributions from individuals named Santosh emphasizes the collaborative nature of scientific advancement in traditional health practices, revealing a network of expertise that influences treatment methodologies.
43) Aditya:
Aditya may refer to a researcher or author in the context of Ayurveda or pharmacology. Recognizing contributions from individuals like Aditya highlights the collaborative aspect of scientific inquiry, emphasizing the shared effort to explore and validate traditional medicinal practices.
44) Bitter:
Bitter substances are often studied in the context of their physiological effects and potential health benefits. In traditional medicine, bitterness can indicate medicinal properties, as many therapeutic herbs have bitter compounds that contribute to digestive and overall health, warranting investigation in treatment formulations.
45) Laxmi:
Laxmi could refer to an individual contributing significantly to Ayurveda or medical research. Mentioning such figures underscores the importance of personal contributions to collective knowledge in the medical field, particularly in validating and promoting holistic health approaches.
46) Tamra:
Tamra refers to copper, often utilized in Ayurveda for its therapeutic properties. The use of Tamra in formulations illustrates the integration of metals in traditional medicine, prompting studies focused on safety, efficacy, and interactions, contributing to understanding and application in modern health contexts.
47) Lauha:
Lauha pertains to iron in Ayurvedic medicine, typically utilized for its restorative properties. Incorporating Lauha in formulations highlights the role of minerals in treating health conditions, prompting exploration of both traditional practices and modern research validating their therapeutic benefits.
48) Kumar:
Kumar may refer to an individual involved in Ayurvedic research, reflecting a collaborative effort in the field. Acknowledging researchers named Kumar underscores the significance of individual contributions in advancing knowledge and practice of traditional healing methodologies in contemporary medicine.
49) Malik:
Malik could be a reference to a researcher or author, emphasizing the collaborative nature inherent in scientific studies. Recognizing individuals named Malik highlights diverse contributions to understanding traditional medicine, supporting an integrative approach to health that values insights from multiple disciplinary backgrounds.
50) Patil:
Patil may denote an individual significant in Ayurvedic practices or research. Acknowledging such contributions reminds us of the collective efforts in advancing the exploration of natural substances, enhancing our understanding of their efficacy and safety in modern health and disease treatment.
51) Sugar:
Sugar is a simple carbohydrate that serves as a primary energy source but is often linked to health issues such as diabetes when consumed excessively. Understanding the role of sugar in metabolic diseases prompts research aimed at dietary guidelines and therapeutic interventions to manage blood sugar levels effectively.
52) Musha (Musa, Musá):
Musa is a genus of plants that includes bananas and plantains. Their nutritional value and potential health benefits make them relevant in dietary studies, particularly concerning glucose metabolism and the impact on conditions such as diabetes, promoting interest in their use in preventive nutrition.
53) Bett:
Bett is likely a reference to a figure in research or an aspect of inquiry. Recognizing contributions from individuals or topics denoted by Bett highlights the importance of individual and collective efforts in advancing knowledge, especially within specific domains of scientific investigation.
54) Gold (Golden):
Gold, often referenced in traditional medicine, particularly in Ayurveda, is considered for its therapeutic properties. The incorporation of gold substances in medicinal formulations reflects historical beliefs in their efficacy, necessitating modern scientific evaluations to assess safety and efficacy in contemporary health settings.
55) Peer review:
Peer review is a process in scientific research where experts evaluate a study's quality, validity, and significance before publication. This process enhances research credibility, ensuring rigorous examination and validation of findings, which is critical for advancing knowledge and maintaining standards in scholarly work.
56) Human body:
The human body serves as the primary subject of study in medicine and health sciences. Understanding its complex biological systems is essential for diagnosing and treating diseases. Advancements in medical research, including pharmacology, focus on systemic interactions and holistic approaches to support overall health and well-being.
57) Pharmacological:
Pharmacological pertains to the study of drugs and their effects on biological systems. Research in this field aims to understand the mechanisms, efficacy, and safety of pharmaceutical agents, which is essential for developing new treatments and improving existing therapeutic practices in healthcare.
58) Tamrabhasma (Tamra-bhasma):
Tamra-bhasma is a form of Ayurvedic medicine made from processed copper. Its uses in traditional healing practices illustrate the integration of minerals into therapeutic approaches, warranting investigation into its pharmacological properties, safety, and effectiveness in promoting health and treating diseases.
59) Rasashastra (Rasa-shastra, Rasasastra):
Rasashastra refers to a branch of Ayurveda that focuses on alchemical processes and the preparation of medicinal substances, particularly metals and minerals. This field emphasizes the preparation and application of bhasma, bridging ancient practices with modern scientific inquiry into their therapeutic roles.
60) Vijayawada (Vijayavada, Vijaya-vada):
Vijayawada is a city in India known for its Ayurvedic practices and medicinal research facilities. Recognizing locations such as Vijayawada highlights regional contributions to traditional medicine studies, showcasing how local resources and practices inform broader discussions in healthcare and pharmacology.
61) Discussion:
Discussion is a significant section in scientific research where findings are interpreted, analyzed, and compared to existing literature. It offers context, implications, and recommendations for future research and practice, enabling scholars to address gaps in knowledge and contribute to the ongoing dialogue in their fields.
62) Collecting:
Collecting data is a fundamental process in research that involves gathering information through observations, experiments, or surveys. Accurate data collection is critical for ensuring validity and reliability in research outcomes, contributing to informed conclusions and recommendations in scientific inquiry.
63) Cutting:
Cutting refers to a method used in experiments to collect samples or administer solutions. In research settings, proper cutting techniques ensure safe and effective handling of biological materials, influencing the quality of results. This process is pivotal in maintaining consistency and accuracy during experimentation.
64) Forest:
Forests are ecosystems that harbor a diverse range of flora and fauna, contributing to biodiversity and ecological balance. In medicinal research, forests provide a rich source of natural products used in traditional practices. Understanding forest ecosystems aids in discovering new therapeutic agents derived from plants.
65) Beta:
Beta often refers to beta cells in the pancreas, which are crucial for insulin production. In diabetes research, understanding the function and health of beta cells is essential for developing effective treatments, as their dysfunction directly contributes to insulin resistance and hyperglycemia.
66) Bile:
Bile is a digestive fluid produced by the liver that aids in the digestion and absorption of fats. In pharmacology, studying bile is essential for understanding drug metabolism and absorption, which informs dosage and formulation strategies for enhancing therapeutic efficacy.
67) Food:
Food encompasses the nutrients and substances consumed by living organisms for energy and sustenance. In health and nutrition research, understanding the roles of different food types impacts dietary guidelines, therapeutic diets, and overall health management, particularly concerning conditions like obesity and diabetes.
68) Line:
In the context of data presentation, 'line' often symbolizes a connection between points in graphical data representation or indicates a boundary in research protocols. Clarity in line definitions fosters better understanding and delineation of key concepts within scientific documentation.
69) Post:
Post refers to any content or communication shared, often in the context of announcements or updates regarding research findings. This promotes engagement and dissemination of knowledge within the academic community, contributing to the visibility and impact of research efforts.
70) Pir:
Peer refers to individuals of equal standing, particularly in an academic context. Peer collaborations and reviews are vital for ensuring quality and accuracy in research, reinforcing a collective effort to enhance the integrity and credibility of scientific studies and their findings.
Other Ayurveda Concepts:
Discover the significance of concepts within the article: ‘A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats’. Further sources in the context of Ayurveda might help you critically compare this page with similair documents:
Diabetes mellitus, Bioavailability, Acute toxicity, Lipid profile, Hyperglycemia, Anti-hyperglycemic activity, Streptozotocin, Sub-acute toxicity, Animal experiment, Histopathological Investigation, Anti diabetic, Wistar rat, Oral gavage, Biochemical parameter, OECD Guideline, Abhrak Bhasma, Nano range.