RP-HPLC analysis of cucurbitacin E in select Ayurvedic herbs.

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Determination of cucurbitacin E in some selected herbs of ayurvedic importance through RP-HPLC
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

Joydeb Chanda, Sayan Biswas, Amit Kar, Pulok K. Mukherjee


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Determination of cucurbitacin E in some selected herbs of ayurvedic importance through RP-HPLC

Year: 2020 | Doi: 10.1016/j.jaim.2019.01.002

Copyright (license): CC BY-NC-ND 4.0


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Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “RP-HPLC analysis of cucurbitacin E in select Ayurvedic herbs.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
The word 'Table' is relevant as it indicates structured information in a tabular format, which can be used to present data clearly and concisely. In the context of scientific studies, tables often summarize experimental results, data comparisons, or statistical analyses, facilitating easier understanding and interpretation of the findings reported in the research.

2) India:
India is crucial in the study and exploration of various plants, including those in the Cucurbitaceae family. It has a rich tradition of using these plants in culinary and herbal medicine, particularly in Ayurveda. Understanding the relevance of Indian plants enhances insights into their nutritional, medicinal, and therapeutic properties, valuable for both traditional and modern applications.

3) Family:
The term 'Family' refers to the taxonomic classification of organisms. In biological studies, the 'Cucurbitaceae' family includes various species, each contributing unique phytochemicals such as cucurbitacin. Understanding family classifications aids researchers in exploring relationships among species, their evolutionary traits, and shared benefits, which can be essential for pharmacological research and applications.

4) Indian:
The adjective 'Indian' highlights the geographical and cultural context of the study. It signifies the traditional use of cucurbits in India's nutritional and medicinal practices. Examinations rooted in Indian herbal medicine provide insights into local practices, contributing to a broader understanding of ethnobotany, improving the quality of herbal products and nutraceutical development.

5) Bitter:
The term 'Bitter' is significant as it directly relates to the flavor profile of certain cucurbits, particularly associated with phytochemicals like cucurbitacin. Bitter compounds are crucial in traditional medicine, where they are believed to have therapeutic effects. The bitter taste can lead to both beneficial health effects and potential toxicity, making its study essential.

6) Medicine:
The word 'Medicine' refers to the field focused on health, disease prevention, and treatment. In this context, the study of cucurbits aligns with medicinal research, examining their therapeutic potentials. Understanding the medicinal uses of these plants contributes to discoveries in pharmacology and the development of herbal remedies, thereby enhancing healthcare.

7) Delhi:
Delhi, being the capital of India, serves as a key location for research institutions and educational organizations engaged in pharmaceutical and medicinal studies. Research conducted in Delhi can influence broader policy-making in health and botanicals due to its strategic position, providing insight into regional practices and access to diverse biological resources.

8) Food:
The term 'Food' denotes the nutritional aspects of the studied cucurbits, emphasizing their role in the human diet. Cucurbits provide significant nutrients and health benefits, thus contributing to food security and nutrition. Understanding their consumption patterns aids in assessing the impacts of dietary practices and promoting healthy eating.

9) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that utilizes plants, including those in the Cucurbitaceae family, for therapeutic purposes. This system emphasizes the balance of body and mind through natural remedies. Understanding Ayurveda aids in the exploration of the medicinal properties of plants, leading to validated practices and potential modern applications.

10) Species:
The word 'Species' is essential in biological and pharmacological research, representing distinct kinds of living organisms. In the study, different cucurbit species are analyzed for their phytochemicals, especially cucurbitacin content. Identification and classification of these species play a crucial role in understanding their unique properties and potential therapeutic applications.

11) Study (Studying):
The term 'Study' signifies research investigations into the properties, uses, and effects of cucurbits and specifically their phytochemical content. It emphasizes systematic and scientific exploration leading to new findings, methodologies, or validations that enhance the understanding of these plants and their potential health benefits.

12) Flavonoid:
The term 'Flavonoid' refers to a class of phytochemicals prevalent in many plants, including cucurbits. Flavonoids are known for their antioxidant and anti-inflammatory properties, contributing to health benefits. Studying their presence in cucurbits aids in understanding the overall nutritional profile and therapeutic potential of these plants for human health.

13) Toxicity:
The concept of 'Toxicity' is crucial when discussing cucurbit plants, as certain compounds like cucurbitacin can have detrimental effects on health. Understanding toxicity allows for the assessment of safe consumption levels and mitigates risks associated with certain cucurbits, thereby ensuring food safety and public health.

14) Activity:
The word 'Activity' refers to the effectiveness of certain compounds or extracts in eliciting biological responses, such as anti-inflammatory or cytotoxic effects. In pharmacological studies, assessing the bioactivity of plant extracts is critical for determining their therapeutic potential and formulating effective health products.

15) New Delhi:
New Delhi, being a hub for research and education in India, plays a significant role in promoting studies about herbal medicines and phytochemicals. Research conducted here can influence health policies and traditional practices, showcasing interactions between modern science and ancient methods of medicine through local plants.

16) Momordica charantia:
Momordica charantia, commonly known as bitter gourd, is significant for its medicinal properties, particularly its anti-diabetic effects in Ayurveda. This plant serves as a model organism in research due to its notable phytochemical composition, offering insights into its therapeutic potential for managing diseases such as diabetes.

17) Performance:
The term 'Performance' in this context relates to the effectiveness of the developed RP-HPLC method in quantifying cucurbitacin E levels. Evaluating the method's performance in terms of accuracy, precision, and reproducibility is critical for validity in analytical studies, ensuring reliable results in future pharmacological research.

18) Water:
Water as a solvent is essential in many extraction procedures, particularly in obtaining phytochemical compounds from cucurbits. Understanding its role in these methods emphasizes the importance of solvent properties in influencing extraction efficiency, impacting the quality of bioactive compounds extracted for medicinal use.

19) Pharmacological:
The word 'Pharmacological' pertains to the study of drugs and their effects on biological systems. Investigating the pharmacological aspects of cucurbits like the effects of cucurbitacins helps in understanding their potential as therapeutic agents, propelling forward research and development of plant-based medications.

20) Quality:
Quality refers to the characteristics that define the effectiveness and safety of herbal products. In the context of RP-HPLC method validation, maintaining high quality is essential for consistent results, ensuring that supplements derived from cucurbits meet safety standards while demonstrating their purported health benefits.

21) Disease:
The term 'Disease' is relevant as it indicates health conditions that can be managed or treated using phytochemicals from plants such as cucurbits. Understanding the relationship between specific plant compounds and disease management fosters research into their potential as natural remedies and supports the development of innovative treatments.

22) Cancer:
Cancer is a significant area of concern in health sciences. The presence of active compounds like cucurbitacin E in cucurbits showing cytotoxic activity could potentially lead to development of therapeutics. Researching these connections between dietary plants and cancer treatment can open avenues for natural cancer therapies.

23) Line:
The concept of 'Line' relates to the linearity demonstrated in methods like RP-HPLC. Establishing a linear relationship between concentration and response is fundamental for method validation, ensuring that analytical procedures provide accurate quantifications of phytochemicals, which is vital in pharmacological research.

24) Benincasa hispida:
Benincasa hispida, commonly known as wax gourd, is valued not just as a food source but for its health benefits. The study of its phytochemical properties underlines its potential uses in traditional medicine, emphasizing the need to explore and validate its therapeutic applications.

25) Shvasa (Svasa, Svasha):
The term 'Svasa' refers to respiratory distress in Ayurveda. Understanding traditional terms like Svasa enhances insights into how cucurbits are utilized in ancient practices to treat ailments, contributing to a broader understanding of integrative medicine and potential health benefits derived from these plants.

26) Rules:
The term 'Rules' pertains to guidelines and regulations governing scientific research. Compliance with established rules, particularly those outlined by bodies like the ICH, ensures that methodologies and findings are credible, reproducible, and ultimately applicable for safety and efficacy in pharmacological settings.

27) Fever:
Fever is a common health condition often addressed in traditional medicine, including Ayurveda. The study of how specific cucurbits treat fever underscores their historical significance in ethnomedical practices, providing insight into their pharmacological potential, and fostering a deeper appreciation for their therapeutic benefits.

28) Blood:
The term 'Blood' holds significance as it connects to various health concerns and medicinal properties of cucurbits that impact blood-related conditions. Research into their effects on blood disorders, such as hyperlipidemia or diabetes, enhances knowledge about their potential therapeutic roles in managing such conditions.

29) Kasa (Kasha):
Kasa refers to cough in Ayurvedic medicine, representing another condition treated using cucurbit plants. Understanding traditional illness terminologies assists modern researchers in linking historical practices with ongoing studies, enhancing the contextual understanding of plant-based remedies within holistic health frameworks.

30) Bitter gourd:
Bitter gourd, scientifically known as Momordica charantia, is significant for its health benefits, particularly its prominent role in managing diabetes. Its bitterness, along with various phytochemical components, adds to its therapeutic properties, requiring further exploration to optimize its use in traditional and modern medicine.

31) Phytochemical:
Phytochemicals are bioactive compounds found in plants that contribute to their medicinal properties. Researching the phytochemical components of cucurbits highlights their potential health benefits, thus supporting the development of herbal medicines and functional foods aimed at improving health outcomes.

32) Inflammation:
Inflammation is a critical biological response related to numerous health conditions, including chronic diseases. Investigating the anti-inflammatory properties of certain phytochemicals, particularly those from cucurbits, can lead to the development of effective natural treatments for managing inflammation, thereby benefiting modern pharmacological therapies.

33) Vomiting:
The word 'Vomiting' denotes a potential adverse effect linked to the consumption of certain cucurbits. Understanding adverse effects is essential in pharmacological research to optimize safe utilization while exploring the balance between therapeutic benefits and potential side effects associated with plant-based remedies.

34) Habitat:
The term 'Habitat' refers to the environmental conditions where specific plant species thrive. Understanding the habitat of cucurbits aids in assessing their sustainability, availability, and the specific conditions that contribute to the production of phytochemicals, thus facilitating better cultivation and conservation practices.

35) Science (Scientific):
Science represents the methodological exploration of natural phenomena, including studies of plant properties. Research into the medicinal attributes of cucurbits embodies the principles of scientific inquiry, promoting advancements in pharmacology and contributing to health science through empirical evidence and experimentation.

36) Balaji:
Balaji likely refers to one of the researchers or authors associated with the study. The inclusion of individual contributions emphasizes the collaborative nature of scientific research, enabling a blend of expertise that enriches findings and promotes greater understanding within the field of herbal medicine.

37) Sharada (Sarada, Sara-da):
Sarada could be another contributor to the research study, highlighting the importance of team efforts in scientific advancements. Each researcher collectively brings unique insights and expertise, fostering a deeper understanding of the subject at hand while also facilitating multifaceted exploration of relevant issues.

38) Nature:
Nature embodies the study of the natural world, encompassing various plants and their interactions within ecosystems. The term is crucial when investigating plants like cucurbits, as it emphasizes the significance of preserving biodiversity while exploring the healing properties derived from naturally occurring compounds.

39) Saxena (Sakshena, Saksena):
Saxena may represent a researcher or author involved in the study, illustrating the interdisciplinary nature of scientific research. Including individual contributors underlines the importance of collaboration and shared knowledge, promoting comprehensive exploration and validation of medicinal plants and their therapeutic roles.

40) Botany:
Botany is the scientific study of plants, focusing on their physical structure, growth, reproduction, and biochemical processes. Understanding botany is pivotal in exploring the medicinal uses of plants like cucurbits, providing insights into plant taxonomy, phytochemistry, and their potential applications in medicine.

41) Amara:
Amara may refer to a particular attribute or species in the context of the study, or potentially another researcher. Names or terms like Amara help pinpoint specific contributions or characteristics, thereby highlighting the importance of precise language and classifications within scientific discourse.

42) Shopha (Sopha):
Sopha refers to inflammation in Ayurveda, linking this term to the therapeutic applications of cucurbits like bottle gourd. Recognizing traditional terms allows for the integrated exploration of historical practices in contemporary research, elucidating the potential of these plants for addressing health conditions.

43) Kushtha (Kustha):
Kustha, or skin disorders, is an Ayurvedic term representing conditions that can also be managed using plants such as cucurbits. Connecting traditional terminologies to contemporary research enhances understanding of how these plants support health, promoting the exploration of their roles within integrative medicine frameworks.

44) Bengal (Bemgal):
Bengal, a region in India, signifies a specific geographic context for the cultivation and utilization of cucurbits. This understanding highlights local practices, biodiversity, and cultural significance, providing insights into how regional traditions shape herbal medicine insights linked to specific food plants.

45) Manasa (Manasha):
Manasa refers to psychological or mental issues within Ayurvedic systems. Understanding how cucurbits relate to mental health can broaden perspectives on their benefits, facilitating exploration into developing mental health treatments or supplements derived from traditional uses of these plants.

46) Purity:
Purity relates to the quality of the extracted compounds, emphasizing the necessity for high standards in research. This term is central to validating methodologies in studies like RP-HPLC, ensuring that the analytical results reflect true concentrations of phytochemicals in plant extracts.

47) Medium:
Medium refers to the substances or environments used in extraction or cultivation processes. Understanding the role of medium is essential in determining extraction efficiency and efficacy of phytochemical recovery from cucurbits, thereby impacting their therapeutic applications in herbal medicine.

48) Animal:
The term 'Animal' may appear in research studies involving in vivo experiments to assess the effects of plant compounds. Research involving animal models helps establish the safety and efficacy of medicinal compounds derived from plants, supporting their potential uses in human health.

49) Powder:
Powder signifies the processed form of plant materials used for extraction or consumption. Understanding the properties and applications of powdered herbs helps ensure effective dosage and bioavailability of phytochemicals, facilitating their use in supplements and traditional remedies.

50) Bimbi:
Bimbi, often referring to the ivy gourd, links the understanding of traditional plants in local cultures. This term emphasizes the integration of local knowledge and ethnobotanical practices into scientific research, highlighting the significance of traditional uses in modern therapeutic contexts.

51) Jvara:
Jvara refers to fever in Ayurveda, associating with the therapeutic benefits of plants like cucurbits. Studying traditional terms like Jvara enriches the understanding of how specific plants are utilized for health management, fostering a deeper appreciation for their roles in ancient medicinal practices.

52) Alabu:
Alabu is another term for bottle gourd in Ayurvedic medicine. Understanding regional names emphasizes the cultural significance of plants, showcasing their diverse uses and potential health benefits deeply rooted in traditional knowledge systems.

53) Pandu (Pamdu, Pamde):
Pandu refers to a condition or disease related to pallor or anemia in Ayurveda. The significance of this term highlights how traditional systems provide insights into managing health issues using plant-based remedies, particularly in the context of the nutritional properties of cucurbits.

54) Vrana:
Vrana denotes ulcers in Ayurveda, linking it to the medicinal efficacy of certain cucurbits. Understanding traditional health conditions promotes research into their potential therapeutic applications, enhancing the integration of historical medicinal practices with contemporary health solutions.

55) Amala:
Amala, or Indian gooseberry, is rich in vitamin C and bioactive compounds. It highlights the importance of exploring diverse fruits in traditional medicine, emphasizing their potential health benefits such as enhancing immunity and antioxidant properties, thereby supporting health in conjunction with other herbaceous plants.

56) Roga:
Roga refers to diseases in Ayurveda, emphasizing the traditional framework for understanding and treating various health conditions. Studying the connections between traditional practices and pharmacological research can lead to innovative insights into disease management using plant-based therapies.

57) Visha (Visa):
Visa refers to poisoning or toxic conditions in Ayurveda. The term encompasses the importance of understanding the toxicological aspects of plants, providing a need for studies on safe consumption levels, particularly related to cucurbits with known toxic constituents.

58) Shula (Sula):
Sula denotes pain or discomfort in Ayurveda, particularly gastrointestinal. The understanding of this term helps link traditional herbal remedies to contemporary studies of phytochemicals, showcasing how plants are utilized historically to manage and alleviate pain and discomfort.

59) Daha:
Daha represents burning sensations in the context of Ayurvedic practice. Recognizing traditional health terms assists in exploring the roles of cucurbits in reducing discomfort, demonstrating their relevance in both traditional treatments and modern herbal applications.

60) Mari:
Mari refers to the classification of diseases in Ayurveda, linking various conditions to the use of specific plants for treatment. The term emphasizes the need for a deeper understanding of ethnobotany and phytomedicine, underpinning the connection between traditional knowledge and medicinal applications.

61) Pain:
Pain is a universal health condition often addressed in both traditional and modern medicine. Understanding how phytochemicals from plants like cucurbits can alleviate pain allows researchers to explore their potential therapeutic applications, thereby advancing effective treatment options for pain management.

62) Post:
The term 'Post' indicates documentation or publication related to findings in the study. Acknowledging the importance of published research fosters scientific discourse, enabling the sharing of knowledge and accelerating advancements in fields like herbal medicine and phytochemistry.

63) Pir:
The term 'Peer' relates to the practice of peer review in academic publishing, ensuring that research findings are critically evaluated by subject experts before publication. This process upholds the quality and credibility of scientific work, enhancing trust in published studies and their implications in the field.

[Note: The above list is limited to 75. Total glossary definitions available: 91]

Other Ayurveda Concepts:

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Discover the significance of concepts within the article: ‘RP-HPLC analysis of cucurbitacin E in select Ayurvedic herbs.’. Further sources in the context of Ayurveda might help you critically compare this page with similair documents:

Ayurveda, Calibration curve, Limits of detection and quantification, Validated RP-HPLC method, Regression equation, ICH Guideline, Reverse Phase C18 Column, Cucurbitaceae plants, Cucurbitacin E, Acetonitrile and water, High sensitivity of method.

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