Medicinal plants: Adjuncts to TB treatment to prevent liver damage.

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Medicinal plants: Adjunct treatment to tuberculosis chemotherapy to prevent hepatic damage
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

Neelam Mangwani, Pawan Kumar Singh, Vipin Kumar


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Medicinal plants: Adjunct treatment to tuberculosis chemotherapy to prevent hepatic damage

Year: 2020 | Doi: 10.1016/j.jaim.2019.02.004

Copyright (license): CC BY-NC-ND 4.0


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Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Medicinal plants: Adjuncts to TB treatment to prevent liver damage.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
A drug is a chemical substance used to diagnose, cure, treat, or prevent diseases. In the context of the article, it refers to anti-TB drugs whose potential toxicity and hepatotoxic effects are discussed in relation to the use of medicinal plants to mitigate side effects during tuberculosis treatment.

2) Tuberculosis:
Tuberculosis (TB) is a contagious and often severe airborne disease caused by the bacterium Mycobacterium tuberculosis. In this research context, the focus is on the relationship between TB treatment and its resultant side effects, particularly liver toxicity from anti-TB drugs, highlighting the need for complementary medicinal approaches.

3) Activity:
Activity refers to the biological effects or actions of substances, particularly drugs or phytochemicals, on living organisms. In this review, the term relates to the pharmacological effects of medicinal plants against Mycobacterium tuberculosis and their hepatoprotective properties, crucial for effective tuberculosis management.

4) Phytochemical:
Phytochemicals are naturally occurring bioactive compounds found in plants responsible for their color, flavor, and disease resistance. They are key components in herbal medicine and are the focus of this paper regarding their therapeutic effects against TB and their role in alleviating drug-induced liver toxicity.

5) Sharman (Sarma, Sharma, Sarman):
Sharma is likely a reference to the authors of studies mentioned in the text. The surname is associated with multiple studies regarding the dosages and effectiveness of herbal treatments for drug-induced complications, implying the author’s contributions to the understanding of herbal medicine's efficacy in treating TB.

6) Toxicity:
Toxicity is the degree to which a substance can harm living organisms. In the context of the article, the toxicity of anti-TB drugs is analyzed, especially its implications on liver function, showcasing the significance of finding herbal remedies that can alleviate such toxic effects during treatment.

7) Table:
Table refers to a systematic arrangement of data or information, often used to summarize findings or present comparative analysis in research. While not explicitly detailed in the text, tables can provide critical summaries of plant activities, synthesis, and interactions with drugs in the broader investigation of the study.

8) Study (Studying):
A study refers to a detailed examination or analysis of a particular topic or question. In this context, it pertains to the various research efforts to understand the effects of phytochemicals in treating TB and their protective roles against the adverse effects of conventional TB therapies.

9) Disease:
Disease refers to a pathological condition of a bodily part, an organism, or system resulting from various causes. The article discusses tuberculosis as a significant global disease, examining how both synthetic drugs used to treat it and herbal remedies can interact and influence health outcomes.

10) Kumar:
Kumar is another surname that may represent a researcher or author involved in the studies referenced in the text. The inclusion of various authors like Kumar reinforces the collaborative nature of studies related to tuberculosis, herbal remedies, and their pharmacological properties.

11) Medicine:
Medicine denotes the science of diagnosing, treating, and preventing illness. The text discusses the use of traditional medicine, particularly herbal remedies, as adjuncts to conventional TB treatments, highlighting the importance of integrating diverse medical practices in achieving better patient health outcomes.

12) Indian:
Indian refers to anything related to India, a country rich in biodiversity and traditional medicine practices. This is significant in the context of the article, as many medicinal plants with potential anti-TB and hepatoprotective activities originate from India, contributing to the treatment strategies explored.

13) Food:
In this context, food relates to dietary elements that may include natural products rich in phytochemicals. The traditional use of certain plants as food and their potential health benefits underlines the integrated view of diet and medicine in managing diseases, including tuberculosis.

14) Inflammation:
Inflammation is the body's response to injury or infection, characterized by redness, swelling, pain, and heat. The article examines how anti-TB drugs can cause inflammation, particularly in the liver, and discusses the importance of phytochemicals in reducing inflammation during TB treatment.

15) Gupta:
Gupta likely refers to an author or researcher whose work is referenced in the studies on herbal remedies. The inclusion emphasizes the collaborative efforts and various contributions of researchers investigating the efficacy of traditional herbs in combating tuberculosis and its side effects.

16) Rich (Rch):
Rich describes the abundance or high concentration of certain qualities, such as phytochemicals in medicinal plants. The text suggests that many plants possess a rich array of bioactive compounds that provide therapeutic benefits, reinforcing their potential role in enhancing TB treatment efficacy.

17) Berberis aristata:
Berberis aristata is a medicinal plant known for its pharmaceutical properties, particularly in traditional medicine. The article discusses its potential in treating tuberculosis and mitigating the side effects of anti-TB drugs, exemplifying how herbal solutions can complement conventional therapies for better health outcomes.

18) Developing:
Developing refers to nations undergoing progress in various aspects, particularly in healthcare. The article addresses issues faced in developing countries regarding tuberculosis treatment, emphasizing the reliance on both modern and traditional medicine to tackle health challenges effectively.

19) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine, emphasizing balance in bodily systems through herbal treatments, diet, and lifestyle. Its principles serve as a basis for exploring the integration of dietary herbs in the treatment of diseases such as tuberculosis, thus providing a holistic health perspective.

20) Species:
Species denote a group of plants or organisms classified based on shared characteristics. The review discusses multiple species of medicinal plants that might exhibit hepatoprotective and antimycobacterial activities, showcasing the rich biodiversity available for exploration in treating diseases like tuberculosis.

21) India:
India, a country known for its diverse flora and traditional medicine systems, plays a central role in the discussion of the article. The indigenous knowledge of using herbal remedies reflects the significance of traditional practices alongside contemporary medical approaches in addressing diseases like tuberculosis.

22) Toxicology:
Toxicology is the study of the adverse effects of chemicals on living organisms. The article discusses the toxicological aspects of anti-TB drugs, highlighting the critical need for remedies that can counteract toxic effects while enhancing the safety and efficacy of tuberculosis treatments.

23) Flavonoid:
Flavonoid refers to a class of plant secondary metabolites known for their antioxidant properties. The text mentions flavonoids as significant components of herbal medicines that can help alleviate liver damage caused by anti-TB drugs, emphasizing their therapeutic relevance in treatment regimens.

24) Animal:
Animal refers to organisms used as models in research studies. The text mentions animal studies exploring the hepatoprotective effects of various medicinal plants, underscoring the importance of preclinical research in understanding the efficacy and safety of potential herbal treatments for human diseases.

25) Egypt:
Egypt is significant as a geographical region with its own traditional medicine practices. The article suggests collaboration or comparative studies against medicines used in other cultures, emphasizing a global approach to understanding the treatments and outcomes related to tuberculosis and other diseases.

26) Mitra:
Mitra likely represents a researcher whose contributions are cited in the studies reviewed in the article. The inclusion of various authors including Mitra highlights the collaborative nature of scientific research, providing insights into the roles of different herbal remedies in combating diseases.

27) Death:
Death signifies the end of life and is a serious concern related to untreated or poorly managed diseases like tuberculosis. The article discusses the mortality rates linked to TB and the importance of effective treatments, including herbal adjuvants to improve patient outcomes and reduce fatalities.

28) Ter:
Ther might refer to the word 'therapy', focusing on the treatment strategies discussed in the article. It underlines how integrating various therapeutic approaches, including medicinal plants and traditional practices, can enhance the management of tuberculosis and its associated side effects effectively.

29) Antibiotic (Antibacterial):
Similar to anti-bacterial, antibacterial focuses on agent effects that combat bacterial infections. This term is crucial in the article as it highlights the potential of herbal remedies to support conventional TB treatments, particularly in developing resistance against multi-drug resistant strains of the bacteria.

30) Chemotherapy:
Chemotherapy usually refers to the treatment of disease using chemical substances, particularly in cancer and infections. In the article, it discusses the use of chemotherapy in treating TB and the potential damages caused by such treatments, emphasizing the need for protective supplementary therapies.

31) Viti:
Viti might refer to a reference for a researcher or link to a broader concept in the context of the discussion on conventional and herbal medicine. The exact relevance would depend on a related study or findings elaborated in the full article.

32) Bile:
Bile is a digestive fluid produced by the liver essential for fat digestion. In the context of the article, discussions on bile may relate to liver functions affected by anti-TB drugs, with an emphasis on protecting liver health through herbal interventions.

33) Pari:
Pari likely refers to a researcher, linking to studies that highlight the benefits of specific phytochemicals in managing TB treatment side effects. The name symbolizes contributions of authors documenting traditional medicine efficacy within the research scope.

34) Line:
Line likely references a line of treatment or therapeutic regime established in medical practice. The context may refer to first-line anti-TB medications and the need for adjunct therapies, such as herbal treatments to address their adverse side effects.

35) Glycyrrhiza glabra:
Glycyrrhiza glabra, commonly known as licorice, is a medicinal plant known for its hepatoprotective and anti-inflammatory properties. This singular plant is examined in the article for its potential role in alleviating liver damage caused by anti-TB drugs, highlighting its therapeutic significance.

36) Terminalia chebula:
Terminalia chebula is a medicinal plant with antioxidant properties known for its protective effects on liver health. The article references it to examine its potential benefits in combating hepatotoxicity induced by anti-TB treatment, reinforcing the value of herbal remedies.

37) Adhatoda vasica:
Adhatoda vasica is a herb well-known for its respiratory health benefits and antitubercular activity. Its inclusion in the article emphasizes the importance of integrating traditional knowledge in pharmacological studies for enhancing treatment efficacy against diseases like tuberculosis.

38) Curcuma longa:
Curcuma longa, commonly known as turmeric, is recognized for its anti-inflammatory and antioxidative properties. The article mentions it concerning its potential role in hepatoprotection during anti-TB therapy, demonstrating how traditional spices can contribute to modern medicinal practices.

39) Pharmacological:
Pharmacological pertains to the branch of medicine that focuses on the uses, effects, and actions of medications. The article discusses pharmacological research related to the efficacy of medicinal plants in managing drug-induced toxicity in TB treatments, stressing a multi-faceted approach to therapy.

40) Vitis vinifera:
Vitis vinifera, known as grape, is acknowledged for its health benefits, particularly its antioxidant properties. The text highlights its relevance as a phytochemical source that may aid in supporting conventional tuberculosis treatments, underpinning the therapeutic potential of dietary plants.

41) Pharmacology:
Pharmacology is the scientific study of drug action and interactions within biological systems. Within this text, pharmacology relates to the efficacy and safety assessment of herbal medications used alongside conventional TB treatments, illustrating the impact of drug-plant interactions.

42) Purification:
Purification refers to the processes used to isolate active compounds from medicinal plants. In the context of this article, methodologies for extracting and evaluating the pharmacological properties of phytochemicals underscore the importance of rigorous scientific methods in herbal remedy development.

43) Shrotriya (Srotriya):
Shrotriya may denote another contributor to the research studies mentioned within the text. Their work reinforces the collective scientific effort in documenting the efficacy of medicinal herbs in mitigating adverse health effects caused by pharmaceutical treatments.

44) Mahapatra (Maha-patra):
Mahapatra likely refers to a researcher noted in studies cited throughout the article. It emphasizes the diversity of authors working in the field, focusing on the exploration of plant-based remedies for tuberculosis and their pharmacological implications.

45) Knowledge:
Knowledge signifies the understanding gained through experience or education in a specific domain, such as herbal medicine. In this context, integrating indigenous medical knowledge with scientific insight is vital for leveraging the therapeutic benefits of traditional plants in TB treatment.

46) Shyamala (Syamala):
Shyamala may represent a contributing researcher in studies related to medicinal plants. This name underscores the collaborative and international nature of scientific inquiry aiming for innovative solutions in treating diseases like tuberculosis using plant-derived compounds.

47) Channel:
Channel refers to the pathways or mechanisms through which substances (like drugs or phytochemicals) exert their effects. In the article, this may relate to how certain herbal compounds influence liver function and mitigate toxicity from traditional anti-TB therapies.

48) Anantan:
Anandan likely denotes one of the authors or researchers involved in the studies cited in the text. Their mention indicates the collaborative nature of exploring herbal treatments, bringing attention to multiple perspectives in the field of research.

49) Vaidya:
Vaidya, often a term for a practitioner of Ayurveda, emphasizes the link between traditional medicine and contemporary health practices. Citing Vaidya acknowledges the contributions made by traditional systems in the development of new therapeutic approaches to treat diseases.

50) Rajput:
Rajput may reference a contributing researcher within the discourse of the article. The presence of various authors enhances the study’s credibility, showcasing the pooling of knowledge and expertise related to herbal remedies in treating tuberculosis.

51) Salina (Shalina):
Salina might signify a researcher involved in related studies on medicinal plants. Their work is crucial in the ongoing exploration of effective treatment options against tuberculosis, reinforcing the value of collaboration in scientific research.

52) Punjab:
Punjab is a region in India known for its rich agricultural biodiversity and traditional medicinal practices. This geographical reference within the article highlights the local herbal treatments available for serious diseases like tuberculosis, emphasizing cultural significance in healthcare.

53) Nature:
Nature refers to the collection of living organisms and their environments. The article emphasizes the importance of harnessing natural resources, such as medicinal plants, for innovative treatment strategies against diseases like tuberculosis in an ecological and sustainable manner.

54) Saxena (Sakshena, Saksena):
Saxena likely refers to a researcher who contributed to the studies referenced in the text. The mention of various authors including Saxena reflects the collaborative research environment, enriching the scientific discourse surrounding medicinal plants and their therapeutic potential.

55) Kappa:
Kappa commonly refers to a protein in the body, such as those involved in immune responses or signaling pathways. The article may discuss its relevance in the context of understanding liver function and inflammatory responses influenced by herbal treatments.

56) Satti:
Satti may denote a researcher involved in the studies referenced in the article. This inclusion acknowledges the broad spectrum of contributors exploring traditional herbal medications and their role in managing tuberculosis and related side effects.

57) Patil:
Patil likely refers to an author or researcher pertinent to the studies cited within the text. Their contributions underline the collective effort in researching effective management strategies for diseases such as tuberculosis through herbal and traditional medicine.

58) Chang:
Chang could represent another researcher contributing to the studies noted in the article. Their mention emphasizes the international collaboration in exploring medicinal plants that can assist in treating tuberculosis, showcasing the diversity of scientific input in the field.

59) Fight:
Fight in this context refers to the efforts to combat diseases, particularly tuberculosis. It suggests the various strategies, including the use of herbal remedies, to enhance treatment efficacy and overcome the challenges related to drug resistance and side effects.

60) Guti:
Guti might reference a researcher involved in related studies. This mention reflects the collaborative approach in addressing tuberculosis treatment challenges, highlighting the significance of combined efforts in scientific research on herbal medicine.

61) Jana:
Jana seemingly represents a contributor among the authors cited in the article. Their contributions enhance the overall understanding of the efficacy of herbal remedies in supporting traditional treatments against diseases like tuberculosis.

62) Devi:
Devi likely denotes a researcher or author who has contributed significantly to the studies referenced. Their work strengthens the emphasis on the potential of traditional herbal medicines in mitigating the effects of conventional TB therapies.

63) Suri (Shuri):
Suri may refer to another researcher noted in the studies within the article. Their inclusion emphasizes the collaborative nature of research into herbal treatments and the medicinal properties of plants for combating serious diseases such as tuberculosis.

64) Alam (Alaṁ):
Alam might signify a researcher contributing to the studies mentioned in the text. The reference highlights the collaborative effort required to explore and validate the role of traditional plant-based therapies in managing diseases like tuberculosis.

65) Beta:
Beta is often a reference to a form of an organism or substance. It might also be indicative of biochemical compounds being studied for their pharmacological effects. The word could relate to exploring variations in the effectiveness of certain treatments or compounds.

66) Dang:
Dang could represent a researcher involved in studies that inform the article's findings. Recognition of various contributors underscores the collaborative scientific environment, aiding in the exploration of herbal remedies for diseases such as tuberculosis.

67) Diet:
Diet refers to the kinds of food consumed by individuals. In the article context, it highlights the importance of plant-based diets and traditional foods that not only provide nutrition but also offer medicinal benefits against various diseases, including tuberculosis.

68) Crop:
Crop refers to cultivated plants that are harvested for food, fiber, or other economic purposes. This term is relevant when discussing agricultural practices surrounding naturally occurring medicinal plants that may contribute to the treatment of diseases like tuberculosis.

69) Male:
Male, in this context, is likely referring to the subjects used in animal studies. It underscores the demographic characteristics of study participants and how these factors may influence the outcomes of research examining the effects of treatments on health.

70) Life:
Life encompasses the state of being alive, often associated with health and wellness. The article emphasizes the importance of maintaining health through traditional and modern medicine approaches, particularly in managing diseases like tuberculosis effectively.

71) Tinospora cordifolia:
Tinospora cordifolia, also known as Guduchi, is a significant medicinal herb recognized for its immunomodulatory and hepatoprotective properties. The article emphasizes its potential applications in enhancing the efficacy of treatments while minimizing drug-induced liver toxicity in tuberculosis management.

72) Withania somnifera:
Withania somnifera, commonly known as Ashwagandha, is a well-regarded medicinal plant in Ayurvedic medicine. The article discusses its adaptogenic properties and potential therapeutic roles in mitigating the adverse effects of anti-TB drugs, showcasing traditional medicine’s relevance in modern healthcare.

73) Piper longum:
Piper longum, known as long pepper, is important in Ayurvedic medicine for its properties in respiratory health. The text underscores its potential usage in enhancing antitubercular effects and addressing side effects from tuberculosis treatments, reinforcing the need for exploring traditional remedies.

74) Peer review:
Peer review is the evaluation of scientific work by one or more experts in the field. The article mentions peer review to highlight the rigorous standards involved in publishing scientific research, ensuring credibility and reliability in the findings related to herbal medicine and tuberculosis.

75) Plumbago zeylanica:
Plumbago zeylanica, known as leadwort, is a medicinal plant with demonstrated pharmacological activities. The focus on this species suggests its possible contributions toward complementary treatments for tuberculosis, reinforcing the importance of exploring diverse phytochemicals in modern medicinal practices.

[Note: The above list is limited to 75. Total glossary definitions available: 92]

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