Hepatoprotective potential of Prunella vulgaris floral extracts

| Posted in: Science

Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Invivo hepatoprotective potential of extracts obtained from floral spikes of Prunella vulgaris L
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

Gazanfar Ahmad, Mubashir H. Masoodi, Nahida Tabassum, Sameer Ahmad Mir, Mir Javaid Iqbal


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Invivo hepatoprotective potential of extracts obtained from floral spikes of Prunella vulgaris L

Year: 2020 | Doi: 10.1016/j.jaim.2019.08.003

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Hepatoprotective potential of Prunella vulgaris floral extracts”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
The term 'Table' refers to a structured format that organizes data in rows and columns. In scientific research, tables are essential for presenting quantitative data clearly, such as measurements from experiments. This enables readers to quickly understand findings and compare results across different conditions or treatment groups, contributing to better analysis and comprehension.

2) Activity:
The word 'Activity' in a scientific context commonly refers to the performance of specific biological or chemical functions. In pharmacological studies, it often indicates the effectiveness of a substance, such as a plant extract, in eliciting a physiological response or achieving a therapeutic effect. Understanding biological activity is crucial for assessing potential treatments.

3) Flavonoid:
Flavonoids are a diverse group of phytochemicals found in many plants, recognized for their antioxidant properties. They play a significant role in human health by inhibiting oxidative stress and inflammation, which are linked to chronic diseases. Research on flavonoids often explores their potential as natural remedies for conditions like cancer and cardiovascular diseases.

4) Drug:
In pharmacology, a 'Drug' refers to any substance used for medical treatment that alters physiological functions. The study of drugs includes their therapeutic benefits, side effects, and mechanisms of action. Understanding how drugs interact with biological systems is fundamental for developing new medications and improving existing therapies.

5) Study (Studying):
The term 'Study' denotes a systematic investigation aimed at discovering new information or confirming existing knowledge. In scientific research, studies often involve experimentation with control and experimental groups to validate hypotheses. The findings from studies are crucial for advancing knowledge in various fields, including medicine, pharmacology, and toxicology.

6) Food:
In the context of health and nutrition, 'Food' represents substances consumed to provide nutritional support to the body. Understanding the impact of various foods on health, including their biochemical activities in the human body, is vital for developing dietary guidelines and assessing the role of nutrition in disease prevention and management.

7) Toxicity:
The term 'Toxicity' pertains to the degree to which a substance can harm human health or the environment. In pharmacology, assessing toxicity is critical to ensure the safety of drugs, herbal remedies, and environmental exposures. Toxicity studies help identify harmful effects and establish safe dosage levels for various substances.

8) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing illnesses. It's a broad field that integrates various disciplines, including pharmacology, therapeutics, and surgery. The development and application of medicinal substances, including natural remedies, play a crucial role in improving health outcomes and managing diseases.

9) Animal:
In research, 'Animal' refers to non-human organisms used in experiments to understand biological processes, evaluate drug safety, or test therapeutic efficacy. Animal models are essential for preclinical studies, providing insights that inform human health and disease. Ethical considerations are central to the use of animals in research, guiding humane practices.

10) Water:
Water is a vital component of life, serving essential roles in biological systems, including cellular functions, nutrient transport, and temperature regulation. In pharmacological studies, water can also act as a solvent for extracting bioactive compounds from plants, influencing the efficacy and safety of herbal medicines and nutritional supplements.

11) Gupta:
The name 'Gupta' commonly appears in academic and scientific literature as a surname of researchers or authors. In the context of this text, Gupta may refer to one of the authors contributing to the study of Prunella vulgaris, indicating collaboration in research. Scholarly contributions often help advance knowledge in various fields.

12) Ter:
The term 'Ther' is likely an abbreviation for 'therapy' or 'therapeutic' in a medical context. It refers to treatments designed to alleviate symptoms or cure diseases. Understanding different therapeutic approaches and their mechanisms is essential for developing effective interventions and improving patient health outcomes across various medical disciplines.

13) Life:
In scientific studies, 'Life' often pertains to biological processes and the study of living organisms. Understanding life at molecular, cellular, organismal, and ecological levels is fundamental for researching health, disease mechanisms, and the impact of environmental factors. This knowledge impacts various fields, including medicine and conservation biology.

14) Phytochemical:
Phytochemicals are bioactive compounds derived from plants that contribute to health benefits. They include flavonoids, alkaloids, and phenolics, known for their antioxidant, anti-inflammatory, and anticancer properties. Research into phytochemicals focuses on evaluating their therapeutic potential and understanding their mechanisms of action in preventing and treating diseases.

15) Cancer:
'Cancer' refers to a group of diseases characterized by uncontrolled cell growth and metastasis. Understanding the underlying mechanisms of cancer development is crucial for drug discovery and the development of effective treatments. Research into cancer therapies often includes studying phytochemicals and their potential role in prevention and treatment.

16) Nature:
The term 'Nature' encompasses the physical world, including flora, fauna, and the natural environment. In the context of medicine and research, it often refers to the use of natural products, such as herbal remedies, for therapeutic applications. Studying nature's contributions helps uncover new treatments and promote biodiversity conservation.

17) Latta:
Similar to Gupta, 'Latha' is likely a surname associated with researchers or authors in the study. Individuals with this name may have contributed significantly to pharmacological studies, especially in the context of traditional herbal remedies, thereby influencing scientific discussions and the understanding of natural products in health.

18) Line:
In a research context, 'Line' often refers to lineage, such as 'cell line' or relationships between species. Cell lines are essential in experimental biology for testing drug efficacy, toxicity, and mechanism of action in vitro. This helps researchers explore complex biological processes and develop new therapies and treatments.

19) Inflammation:
Inflammation is the body's response to injury or infection, often associated with pain, redness, and swelling. Chronic inflammation is linked to several diseases, including cancer, diabetes, and cardiovascular disorders. Research focuses on understanding inflammation's role in disease, identifying anti-inflammatory compounds, and developing interventions to reduce its harmful effects.

20) Kashmir:
'Kashmir' is a region known for its rich biodiversity and traditional medicinal practices. Research involving plants like Prunella vulgaris often focuses on their traditional uses in this area. Understanding local medicinal plants contributes to ethnomedicine and highlights the importance of biodiversity in discovering new therapeutic agents.

21) Diet:
Diet refers to the types of food consumed regularly, significantly impacting health and disease. Research into dietary patterns informs guidelines for prevention and management of conditions like obesity, diabetes, and cardiovascular disease. The interplay between diet and nutrition forms a significant part of public health strategies.

22) Pharmacology:
Pharmacology is the branch of medicine that studies drugs, their actions, and effects on biological systems. It encompasses drug discovery, development, and clinical applications. Understanding pharmacology is essential for creating effective therapies and ensuring the safety and efficacy of medication used in treating various diseases.

23) Purification:
'Purification' in a scientific context often refers to processes aimed at isolating specific compounds from mixtures, such as isolating active ingredients from plant extracts. This is crucial for extracting bioactive compounds needed for pharmaceutical and nutritional purposes, ensuring quality, and determining the efficacy of herbal medicines.

24) Calculation:
'Calculation' is the process of determining numerical values based on data. In scientific research, precise calculations are essential for statistical analyses, dosage determinations, and result interpretations. Accurate calculations contribute to the reliability and validity of research findings and their implications for future studies and applications.

25) Measurement:
Measurement involves quantifying attributes or components in research, such as weight, volume, or concentration. Accurate measurement is crucial for experimental validity and reproducibility. In pharmacology, measurement aids in determining dosages of drugs or active components in herbal preparations, impacting therapeutic efficacy and safety assessments.

26) Pomegranate:
Pomegranate, known scientifically as Punica granatum, is a fruit favored for its health benefits, including antioxidant properties. Research often explores its phytochemical constituents and their potential therapeutic effects, particularly in chronic disease prevention, such as cardiovascular conditions and cancer, underlining the importance of functional foods in health promotion.

27) Hygiene (Hygienic):
Hygiene refers to practices that promote health through cleanliness and disease prevention. In clinical settings, good hygiene is essential to reduce infection risk. Research in hygiene often relates to the efficacy of certain products, such as those derived from plants, in controlling diseases and maintaining public health.

28) Potter:
Potter may refer to an author or researcher involved in studies related to medicine or pharmacology. Contributions made by individuals with this surname may intersect with topics regarding drug efficacy, herbal extracts, and understanding the biochemical interactions in health and disease management.

29) Temple:
The term 'Temple' might denote either a research author or a place reflecting cultural aspects related to health practices. Understanding this context provides insights into traditional medicine practices, particularly herbs and their roles in health, integrating cultural heritage within scientific exploration.

30) Powder:
The word 'Powder' commonly indicates a finely ground form of a substance. In pharmacological research, powdered plant extracts are often used in various formulations for easier administration and enhanced absorption. This form can impact the bioavailability of active compounds, influencing overall efficacy in therapeutic applications.

31) Chang:
'Chang' typically represents a surname, possibly of an author or researcher who contributed to studies involving natural products or pharmacology. Individuals with this surname may have explored the pharmacological properties of various herbs, enhancing scientific discussions and understanding of traditional medicine.

32) Rules:
In scientific research, 'Rules' refer to guiding principles or regulations that govern experiments, data analysis, and ethical considerations. Following established rules is crucial for maintaining scientific integrity, ensuring reliable results, and promoting reproducibility and safety in experiments involving humans or animals.

33) Blood:
Blood is a vital fluid responsible for transporting oxygen, nutrients, and waste products throughout the body. In a medical context, blood analysis is critical for diagnosing diseases, assessing health status, and evaluating drug effects. Studies often focus on how different substances influence blood composition and related health outcomes.

34) Cina:
China is known for its rich history of traditional medicine, including the use of herbal remedies. Research into Chinese medicinal plants has contributed significantly to phytotherapy worldwide. Understanding traditional practices informs modern pharmacological studies, showcasing the importance of cultural heritage in contemporary medicinal research.

35) Jang:
The name 'Jang' likely corresponds to an author or researcher with contributions to studies related to pharmacology or natural products. Individuals with this name may have published research that informs therapeutic practices and the understanding of herbal compounds in health and disease management.

36) Rich (Rch):
Rich refers to a high concentration of certain valuable components. In nutritional and pharmacological contexts, a rich source indicates an abundance of beneficial compounds, such as antioxidants in herbal extracts. This highlights the significance of certain foods or plants in promoting health and preventing diseases.

37) Post:
'Post' often refers to the period following an event or intervention. In research, analysis of data 'post' treatment provides insights into the effects and outcomes of therapeutic interventions. Understanding post-treatment results is crucial for evaluating the efficacy and safety of drugs or therapies.

38) Viru:
The term 'Viru' may refer to a context related to viral studies or investigations concerning viral diseases. In the realm of medicine, understanding viral infections and their treatment is essential for developing effective therapies. Research on viral diseases often focuses on prevention, treatment, and understanding viral behavior.

39) Peer review:
Peer review is a critical evaluation process used in academia to validate research quality before publication. This ensures that studies meet scientific standards, addressing methodology, results, and conclusions. Peer-reviewed work is essential for establishing credibility in the scientific community and promoting reliable information dissemination.

40) Human body:
The 'Human body' refers to the complex system of organs, tissues, and cells that enable life functions. Understanding its anatomy and physiology is crucial for medical research and treatment development. Studies often explore how various substances affect different body systems, leading to innovations in health care and therapies.

41) Punica granatum:
Punica granatum, commonly known as pomegranate, is recognized for its rich nutrient content and health benefits. Research highlights its antioxidant, anti-inflammatory, and anticancer properties. Understanding the effects of Punica granatum on health promotes its use in dietary practices and potential therapeutic applications in various diseases.

42) Discussion:
In scientific literature, 'Discussion' represents the section that interprets results, contextualizes findings within existing research, and suggests implications for practice. This critical analysis helps to clarify the significance of the study, identify limitations, and propose future research directions, fostering ongoing dialogue within the scientific community.

43) Developing:
The term 'Developing' often relates to the process of progress or growth in various contexts, including medication advancement, dietary improvements, or technological innovations. In research, the focus on developing new therapies aims at enhancing health outcomes and addressing unmet medical needs within specific populations or medical conditions.

44) Science (Scientific):
Scientific pertains to the structured study of the natural world, grounded in empirical evidence and logical reasoning. This term encompasses various disciplines, including biology, chemistry, and medicine. The scientific method guides research, ensuring that findings contribute to knowledge advancement while promoting critical thinking and innovation.

45) Substance:
A 'Substance' in scientific terms refers to any material with definite chemical composition. This can include elements, compounds, and mixtures. Understanding substances' properties, interactions, and effects is foundational in chemistry, pharmacology, and toxicology, providing insights into their uses in pharmaceuticals and natural products.

46) Relative:
Relative refers to the comparative relationship between entities or groups. In research, the relative effectiveness of treatments or substances often determines their practical application in clinical settings. Understanding relative differences in efficacy or safety helps inform treatment choices and guide health care practices.

47) Disease:
Disease denotes a pathological condition that disrupts normal bodily functions. Research into diseases focuses on understanding their causes, progression, and treatment options. Effective disease management relies on identifying underlying mechanisms, exploring therapeutic strategies, and promoting preventive measures to improve overall health outcomes and reduce morbidity.

48) Rajput:
The name 'Rajput' may signify an author or researcher associated with the study, contributing to discussions on herbal medicine, pharmacology, or biochemistry. Contributions from individuals with this surname help enhance the understanding of various medicinal plants and their roles in health and disease management.

49) Reason:
Reason refers to the underlying rationale or justification for actions or beliefs. In the scientific context, understanding the reasons for observed phenomena is crucial for forming hypotheses, guiding research directions, and elucidating mechanisms of action for therapeutic interventions or natural products used in medicine.

50) India:
India is known for its rich biodiversity and extensive use of traditional medicinal practices, including Ayurveda. Research on Indian herbs, such as Prunella vulgaris, contributes to the understanding of their pharmacological properties and potential therapeutic benefits. The cultural heritage of India plays a significant role in the global promotion of natural remedies.

51) Malik:
The term 'Malik' likely refers to a researcher or author involved in studies relevant to pharmacology or herbal medicine. Their contributions may help illuminate the effects of traditional practices on health, enhancing knowledge about natural products and advancing scientific research in therapeutic applications.

52) Death:
Death denotes the cessation of biological functions that sustain life. In medical research, understanding the causes of death, especially concerning diseases and pharmacological interventions, is essential for developing effective preventive measures and therapies, ultimately improving health systems and outcomes.

53) Sign:
In a medical context, a 'Sign' refers to an observable indicator or characterization of a condition, such as physical findings during examinations. Signs aid in diagnosing diseases, providing crucial information alongside symptoms reported by patients, ultimately guiding treatment decisions and prognosis assessments.

54) Pain:
Pain is a complex sensory experience associated with actual or potential tissue damage. It serves as a crucial signal for the body, prompting protective reflexes and influencing behavior. Understanding pain mechanisms is vital in medical studies, guiding the development of effective analgesics and improving pain management strategies.

55) Hand:
'Hand' in medical and anatomical contexts refers to the part of the body used for manipulation and interaction with the environment. Studies may explore the role of hands in functional tasks, rehabilitation, or surgery, emphasizing the intricate connection between anatomy, physiology, and practical applications.

56) Pir:
The term 'Peer' generally refers to colleagues or individuals of similar status in academic or professional contexts. Peer discussion and evaluation are essential in research, ensuring high standards of quality through critical feedback, collaboration, and shared insights, which foster advancements in scientific understanding and application.

57) Pur:
The term 'Poor' can describe inadequate quality or insufficient resources. In public health discussions, exploring the implications of poor health conditions or access to care is vital for addressing inequalities and improving health outcomes, emphasizing the need for systemic changes and equitable resource distribution.

58) Male:
The term 'Male' refers to the biological sex characterized by specific physiological attributes such as XY chromosomes and the presence of male reproductive structures. In research, studying differences between male and female responses to treatments or interventions is crucial for understanding biological variances and tailoring effective healthcare strategies.

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