Cajanus cajan leaf extract protects against sleep deprivation memory loss.

| Posted in: Science

Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Protective role of hydroalcoholic extract of Cajanus cajan Linn leaves against memory impairment in sleep deprived experimental rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
This page does not contain the article itself; See source (below) for actual content.

Original source:

This page only sums up technical details and meta-data hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Layeeq Ahmad, Md Mujahid, Anuradha Mishra, Md Azizur Rahman


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Protective role of hydroalcoholic extract of Cajanus cajan Linn leaves against memory impairment in sleep deprived experimental rats

Year: 2020 | Doi: 10.1016/j.jaim.2018.08.003

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Cajanus cajan leaf extract protects against sleep deprivation memory loss.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to the various behaviors or actions observed in the study. In the context of memory impairment and the effects of hydroalcoholic extract on the Sprague Dawley rats, activity levels are crucial for assessing behavioral changes due to treatments, particularly in tests measuring memory and locomotor activities.

2) Drug:
In the context of the study, drugs refer to the administered substances for treatment, including hydroalcoholic extract of Cajanus cajan leaves and piracetam. Investigating their effects on memory impairment in sleep-deprived rats shows the potential therapeutic value of these compounds related to neurological health.

3) Animal:
Animal subjects, particularly adult Sprague Dawley rats, play an essential role in research studies like this one. They allow scientists to explore the effects of treatments in a controlled setting, providing insights into potential human applications of the findings related to memory impairment and neuroprotection.

4) Disease:
Disease in this context relates primarily to Alzheimer's disease or memory impairment resulting from external stressors. Understanding how treatments affect memory-related diseases is a major focus of research, aiming to discover effective therapeutic approaches to mitigate cognitive decline in affected populations.

5) Table:
Table refers to organized presentations of data summarizing findings from the experiments. In scientific studies, tables provide a clear way to display numerical values and results, making it easier for readers to analyze the effects of treatments on variables such as behavior and biochemical activity.

6) Study (Studying):
The study refers to the entire research project aimed at evaluating the protective role of hydroalcoholic extract from Cajanus cajan Linn leaves against memory impairment in rats. It provides structured methodologies, findings, and discussions that contribute to understanding potential treatments for cognitive disorders.

7) Sam (Sham):
Sham refers to the control group of rats that did not receive any treatment but were subjected to the same conditions as other experimental groups. This comparison group is vital for evaluating the true efficacy of the drugs by establishing a baseline for behavior or physiological measures.

8) India:
India is significant as it is the geographical context of the research and the natural habitat of the Cajanus cajan plant. The cultural relevance and traditional medicinal use of various indigenous plants underscore the importance of studying local flora for potential therapeutic benefits.

9) Water:
Water is essential in biological studies. In this research, rats had access to water ad libitum, which ensures hydration during the experimental period. The provision of adequate water resources is crucial for the overall health of the animals and the reliability of experimental results.

10) Lucknow:
Lucknow is the city in India where the study was conducted. It plays a crucial context in terms of the location for plant collection and animal experimentation, influencing the results due to local environmental factors and availability of traditional medicinal knowledge contributing to the study.

11) Pigeon:
Pigeon pea (Cajanus cajan) denotes the specific plant used in this study. Its relevance lies in its traditional uses in Ayurveda for health, particularly its protective effects against oxidative stress and neurotoxicity. Researching its properties underlines the potential of naturally occurring compounds in modern medicine.

12) Delhi:
Delhi, as a major city in India, represents a broader cultural context within which traditional medicine is practiced and medicinal plants like Cajanus cajan may be grown or researched. Its relevance could also pertain to healthcare discussions occurring within urban settings around cognitive ailments.

13) Ulcer:
Ulcer denotes a medical condition often related to gastrointestinal issues. Although this study primarily addresses memory impairment, the presence of ulcer research indicates the multifaceted role medicinal plants may play in addressing various disorders, highlighting the need for comprehensive studies that cover numerous health dimensions.

14) House:
House in the context of this study refers to the animal housing facilities where the rats were acclimatized before the experiment. Proper housing conditions are vital for ensuring the animals' well-being and valid results, as environmental factors significantly affect behavioral and physiological outcomes during testing.

15) Measurement:
Measurement pertains to the quantitative assessment of various parameters such as behavioral activities and biochemical markers in the study. Accurate measurement techniques are crucial to analyzing the efficacy of treatments and understanding their mechanisms of action in relation to memory and cognition.

16) Flavonoid:
Flavonoids are bioactive compounds found in many plants, including Cajanus cajan. Their antioxidant and neuroprotective properties are often investigated for potential benefits in treating conditions like cognitive impairments. Flavonoids could provide insights into the therapeutic effects relating to the plant’s medicinal uses.

17) Learning:
Learning pertains to the cognitive processes involved in acquiring new information or behaviors. As the study assesses memory impairment, understanding learning mechanisms in the context of treatment efficacy emphasizes the importance of cognitive enhancements from potential medicinal interventions.

18) Filling (Filled):
Filled refers to how brain sections or experimental data might show changes due to treatment. In histopathological examinations, the phrase suggests observable alterations in brain tissue characteristics, critical for assessing the plant's protective effects against memory impairments under stress.

19) Pharmacology:
Pharmacology is the branch of science concerned with the study of how drugs interact with biological systems. This study fits into pharmacological discussions by exploring the treatments administered to rats and assessing their impact on cognitive functions, contributing to understanding drug efficacy and safety.

20) Performance:
Performance in the study relates to the capacity of rats to complete tasks, such as navigating a maze. Assessment of these performances is critical in determining the effectiveness of treatments in improving memory functions compared to controls, thus evaluating the impact on cognitive behavior.

21) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine that emphasizes natural healing methods. The study's focus on Cajanus cajan highlights its relevance in Ayurvedic practices as a potential remedy for cognitive disorders, linking traditional knowledge with contemporary pharmacological research.

22) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic formulation made from three fruits, known for its health benefits. Though not directly studied, its mention emphasizes the broader context of natural remedies and their common use in India, possibly relating to the reasoning behind selecting Cajanus cajan in the study.

23) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. This research contributes to the field of medicine by evaluating herbal extracts' effects on cognitive disorders, thus expanding the scope of potential therapeutic agents derived from natural sources.

24) Indian:
Indian refers to the cultural context of the study, highlighting the significance of indigenous plants in traditional health systems. Understanding such contexts supports the relevance of exploring plants like Cajanus cajan, which have longstanding uses in traditional Indian medicine for various health issues.

25) Kumar:
Kumar likely represents a common surname in India associated with one of the authors involved in the study. The inclusion of authors aids in citing and recognizing contributions in scientific research papers, establishing credibility and academic transparency within the research community.

26) Patil:
Patil also represents a surname, possibly of an author contributing to the research. Recognizing individuals by name helps elevate accountability and acknowledgment in the academic and scientific communities, providing a way to trace specific contributions to the body of knowledge.

27) Sugar:
Sugar may refer to dietary components affecting overall health and potentially influencing experimental outcomes. In discussions about cognitive health, the impact of sugar in diet and its relation to disorders is significant, prompting considerations on regulation through dietary means along with medicinal approaches.

28) Death:
Death in this context likely refers to the loss of cognitive function or brain cells associated with conditions like Alzheimer's disease. Understanding the relationship between neurodegenerative diseases and mortality underscores the urgency of researching preventive measures and treatments to enhance life quality.

29) Blood:
Blood is pertinent in assessing physiological changements in living organisms. Studying biochemical markers often involves blood measurements, relating to how treatments affect metabolic and neurochemical processes, which are crucial for understanding drug efficacy in treating neurological diseases.

30) Vegi:
Vegi, likely a surname, probably belongs to one of the researchers. Proper citation and authorship acknowledgment is a key aspect of academic publishing, allowing for recognition of individual contributions to the collective scientific endeavor in this study.

31) Pune:
Pune represents another significant city in India where research and traditional practices continue to thrive. Its mention suggests a broader cultural backdrop for the study, underscoring the integration of local practices and scientific exploration of medicinal plants like Cajanus cajan.

32) Peng:
Peng may refer to an author or researcher involved in the study. The importance of naming individuals in academic publications fosters transparency regarding research contributions, crucial for maintaining the integrity and credibility of scientific discourse.

33) Diet:
Diet encompasses the nutritional aspects affecting health, including cognition. Proper diet consideration is crucial in experiments, as dietary factors can significantly influence results, particularly in studies focused on memory impairment and the efficacy of potential treatments.

34) Cage:
Cage signifies the environment where the experimental animals were housed. Proper housing conditions in cages are vital for ensuring the welfare of the animals and yielding valid, reliable data in studies aimed at understanding the effects of treatments on behavior and cognition.

35) Rich (Rch):
Rich refers to the nutritional composition of plants like Cajanus cajan, which are abundant in bioactive compounds. Exploring the richness of these compounds can lead to valuable insights into their therapeutic potential, establishing a connection between traditional knowledge and modern scientific research.

36) Wall:
Wall may relate to structures within the context of the housing where the rats were kept or even metaphorical barriers in research. Its relevance can extend to discussions about environmental conditions affecting the outcomes of animal studies.

37) Hand:
Hand refers to the exposure of physical interaction either in research methodology or more generally within the context of fieldwork. Understanding how hands-on techniques contribute to better experimental designs is significant for accurate and reliable scientific inquiries.

38) Post:
Post generally denotes the subsequent phase in a process or study. In research discussions, post-treatment evaluations are crucial for monitoring changes and ensuring that the effects of the interventions are assessed adequately, providing insights into the therapeutic efficacy of treatments.

39) Peer review:
Peer review is an essential process in publishing scholarly articles, where experts evaluate the quality and validity of the research before publication. This system helps maintain rigorous scientific standards, ensuring that research findings, like those in the present study, undergo scrutiny for reliability and effect.

40) Discussion:
Discussion in scientific studies refers to the section where results are interpreted, compared with previous work, and implications for future research or clinical practice are outlined. It integrates findings, highlights significance, and addresses potential limitations of the current study.

41) Training:
Training relates to the methodology used in preparing and dosing the animals in the study. Understanding training regimens is fundamental in behavioral experiments, particularly in memory studies, where specific tasks are designed to evaluate the effects of treatments on performance.

42) Relative:
Relative indicates a comparison or connection to another aspect. In studies, emphasizing relative measures provides context to data, facilitating better understanding of treatment effects compared to control groups or baselines—in this case, analyzing the changes in behavior or physiology.

43) Forest:
Forest likely signifies the natural habitat where Cajanus cajan was sourced. Understanding the ecological context enhances knowledge surrounding the natural properties and traditional uses of plants, while also adding to the cultural significance of specific flora within indigenous medicine.

44) Family:
Family in botanical terms refers to the classification group to which Cajanus cajan belongs (Leguminosae). Understanding this classification helps contextualize the plant's properties, linking it to other species with similar therapeutic effects, thereby broadening research horizons in pharmacology.

45) Medium:
Medium typically indicates the environment or substances used for extraction or culture. In the study, the medium relates to the hydroalcoholic solvent used for extracting bioactive compounds, which is pivotal for determining the efficacy of the extracted substances for therapeutic applications.

46) Powder:
Powder refers to the form in which dried plant materials are prepared for extraction processes. The preparation into powder is essential for maximizing surface area, ultimately enhancing the effectiveness and efficiency during the maceration and extraction phases, thus yielding potent extracts for research.

47) Rules:
Rules indicate the guidelines followed in conducting the study, including ethical considerations and standard operating procedures. Adhering to set rules ensures compliance with scientific and ethical standards, thus legitimizing research outcomes and fostering accountability within the scientific community.

48) Cina:
China may reference the source of certain chemicals or materials used in the study. Its mention emphasizes the global context of research and the interconnectedness of various international sources of materials and treatments critical to scientific inquiry and exploration.

49) Food:
Food signifies the diet provided to the animals during the study, which is essential for maintaining baseline health. The nutritional quality of the available food influences the animals' overall condition and, by extension, the reliability of the experimental outcomes.

50) Sign:
Sign refers to an indicator of specific effects or results observed during the study. Understanding signs in scientific contexts is crucial for cataloging observations and correlating them with treatments, thereby assisting in the interpretation of the efficacy and mechanisms of various interventions.

51) Line:
Line may refer to divisions in the methodologies or results sections. Drawing lines between various approaches or outcomes assists in organizing scientific discourse and makes it easier to understand the relationships between multiple variables assessed through the study.

52) Pir:
Peer denotes individuals of similar qualifications who review study submissions. The peer review process fosters a collaborative scientific environment and helps maintain integrity and accuracy in published materials, ensuring that contributions are scrutinized and validated prior to sharing with the broader scientific community.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Consider supporting this website: