Anticataract effects of S. cumini and A. marmelos in diabetic goats

| Posted in: Science

Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Anticataract effects of S. cumini and A. marmelos on goat lenses in an experimental diabetic cataract model
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

A.M. Hajarnavis, P.M. Bulakh


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Anticataract effects of S. cumini and A. marmelos on goat lenses in an experimental diabetic cataract model

Year: 2020 | Doi: 10.1016/j.jaim.2019.08.001

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Anticataract effects of S. cumini and A. marmelos in diabetic goats”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
A table is a structured representation of data, often used in scientific studies to display results in a clear and organized manner. It allows for easy comparisons and understanding of various parameters or outcomes, which helps simplify complex findings and enhances the presentation of research results.

2) Activity:
In the context of biological or pharmacological studies, 'activity' refers to the capability of a substance or treatment to induce a certain effect, such as antioxidant effects or anticataract properties. Activity is often quantified through various assays and is critical for assessing the efficacy of compounds in research.

3) Study (Studying):
Studying involves the examination and analysis of particular phenomena, helping to generate knowledge and understanding of complex subjects. In scientific research, studying biological processes, plant properties, or disease mechanisms allows for advancements in developing treatments and improving health outcomes.

4) Syzygium cumini:
Syzygium cumini, commonly known as Jamun, is a tropical fruit known for its potential medicinal properties. It is particularly noted for its antioxidant effects, which may combat oxidative stress-related diseases like diabetes and cataract. Its phytochemicals are explored for therapeutic applications in various health conditions.

5) Swelling:
Swelling refers to an abnormal enlargement of tissues or organs, often due to inflammation or fluid accumulation. In cataract studies, swelling typically indicates lens opacification or changes in morphology due to oxidative stress or diabetes. Understanding swelling processes is crucial for assessing eye health and treatment effects.

6) Jamun:
Jamun refers to the fruit of the Syzygium cumini tree, known for its deep purple color and sweet-sour taste. This local fruit has been traditionally associated with various health benefits, particularly in managing diabetes and related complications. Its extracts are investigated for potential therapeutic properties against cataract formation.

7) Line:
In research contexts, a 'line' often denotes a trend or a connection among data points. It can also refer to a set of characteristics used to define a group or species, crucial for classification. Understanding such lines is essential in comparing treatment outcomes or biological responses.

8) Aegle marmelos:
Aegle marmelos, popularly known as Bael, is a fruit-bearing tree widely acknowledged in traditional medicine, particularly in Ayurveda. Its leaves, fruit, and roots are used for various therapeutic applications, including antioxidant and anticataract activities. Research focuses on extracting bioactive compounds for their potential health benefits.

9) Phytochemical:
Phytochemicals are naturally occurring bioactive compounds found in plants, which can have prominent health benefits. They include flavonoids, phenolics, and alkaloids that may exert antioxidant or anticancer effects. Assessing phytochemical content in plants like Syzygium cumini and Aegle marmelos is essential for exploring their medicinal potentials.

10) Indian:
Indian refers to aspects related to India, including its culture, language, and traditional practices in medicine, especially Ayurveda. In the context of the discussed study, it denotes local knowledge and plant species utilized in traditional healthcare systems, highlighting the relevance of indigenous approaches to modern health challenges.

11) Substance:
In scientific terms, a substance is any material or compound with a defined chemical composition. It can refer to biological compounds, drugs, or chemicals studied for their effects and efficacy in medical treatments. The analysis of substances is crucial for understanding their roles in health and disease.

12) Animal:
Animals are living organisms that can serve as models for scientific research due to their physiological similarities to humans. In pharmacological studies, animal models help in understanding disease mechanisms, testing drug efficacy, and examining the impact of substances on biological systems, particularly in preclinical research.

13) Disease:
A disease is an abnormal condition affecting the body, often marked by specific symptoms and signs. In the context of the study, diseases such as diabetes leading to cataract highlight the importance of understanding the underlying mechanisms of disease development and the potential for plant-based treatments.

14) Medium:
In scientific research, 'medium' refers to a substance or environment in which biological processes occur or in which organisms are cultured. For example, tissue culture mediums provide the necessary nutrients for maintaining cells or tissues in vitro, making it crucial for experimental studies evaluating drug effects.

15) Rules:
Rules in scientific research set the guidelines for conducting studies, ensuring ethical standards, accuracy, and reproducibility. They help maintain the integrity of research findings. Understanding and adhering to these rules is vital for drawing valid conclusions and contributing reliably to scientific knowledge.

16) Drug:
A drug is a chemically formulated substance used to diagnose, treat, or prevent diseases. In pharmacology, it encompasses a broad range of medications, including those derived from plants, such as the extracts of Syzygium cumini and Aegle marmelos studied for their potential to prevent cataract pathology.

17) Pharmacological:
Pharmacological pertains to the branch of medicine that studies drugs, their properties, effects, and usage. Research focuses on understanding how substances interact with biological systems to affect health outcomes. This is crucial in developing treatments for diseases and optimizing therapeutic strategies.

18) Ghanavati:
Ghanavati likely refers to an author or researcher, indicating contributions to the field of study related to cataracts or diabetes. Acknowledging such individuals highlights collaborative efforts in research, promoting shared knowledge and advancements in understanding the impact of specific substances on health.

19) Zhejiang:
Zhejiang is a province in China known for its rich biodiversity and traditional medicine practices. Research conducted in this region may contribute to the global understanding of medicinal plants and their properties, including the evaluation of antioxidant activities in plants like Aegle marmelos.

20) Javadi:
Javadi likely refers to an author involved in the study of diabetic cataract or similar research fields. Mentioning authors emphasizes the importance of collaborative research efforts that contribute to advancements in medical science and the significance of their findings in clinical applications.

21) Balaji:
Balaji may refer to a researcher or collaborator who has contributed to the study of medicinal plants' effects on diseases such as cataract and diabetes. Such contributors in the research community help foster understanding of the potential therapeutic applications of local flora.

22) Rekha:
Rekha likely denotes an author associated with research in pharmacology or related fields. The inclusion of researchers' names emphasizes their roles in disseminating important findings, which can influence health practices, treatments, and the validation of traditional medicine through scientific methodologies.

23) Kumar:
Kumar refers to an author or researcher, often found in studies related to medicine or pharmacology. Acknowledging contributors like Kumar underscores the importance of teamwork in scientific research and the collaborative effort required to advance knowledge and applications in health and disease management.

24) Water:
Water acts as a solvent in biological systems, allowing nutrients, ions, and other compounds to interact and facilitate various physiological processes. In research, the preparation of plant extracts often involves water, critical for maintaining the integrity of phytochemicals used in therapeutic evaluations.

25) Amla:
Amla, or Emblica officinalis, is a fruit recognized for its high vitamin C content and potent antioxidant properties. Its inclusion in studies emphasizes the broader category of phytochemical-rich fruits used in traditional medicine, expanding knowledge of their potential roles in preventing oxidative stress-related illnesses.

26) Babu:
Babu is likely an author's name associated with research in pharmacology or traditional medicine studies. Recognizing individual contributions is important in following scientific inquiries and understanding the impact of specific researchers on the development of knowledge within the field.

27) Pune:
Pune is a city in India known for its educational institutions and research centers. Studies conducted in Pune contribute to advancements in the understanding of medicinal plants and their effects, shaping local and global perspectives on traditional health practices and their scientific validation.

28) Food:
Food denotes any substance consumed to provide nutritional support for the body. In the context of medicinal plants, food is often examined for its health benefits and potential protective effects against diseases, emphasizing the relevance of dietary choices in overall health management.

29) Ter:
Ther likely refers to 'therapy' or 'therapeutic methods'. In the context of pharmacological studies, it highlights the approaches used to treat diseases. Understanding therapeutic potentials of natural extracts enhances knowledge in managing conditions like diabetes and cataracts.

30) Emblica officinalis:
Emblica officinalis, commonly known as Amla, is noted for its rich nutritional profile and numerous health benefits, particularly its strong antioxidant effects. Studied for its role in traditional medicine, its inclusion across various research emphasizes the significance of understanding phytochemical properties in disease prevention and health enhancement.

31) Peer review:
Peer review is a critical evaluation process used in scientific research where experts assess a study's quality, validity, and relevance before publication. This process serves to maintain scientific integrity, ensure accuracy, and enhance the credibility of research findings in the scientific community.

32) Accumulation (Accumulating, Accumulate):
Accumulation in biological terms often refers to the buildup of substances in cells or tissues, which can lead to various health complications. In studies on cataracts, the accumulation of glucose or oxidative products can contribute to lens opacification and related diseases, necessitating further research into preventative methods.

33) Measurement:
Measurement is the process of quantifying variables or outcomes in scientific research. In pharmacological studies, accurate measurement of biochemical parameters is crucial for validating results, comparing treatment effects, and establishing the efficacy of compounds, thus contributing to the robustness of research findings.

34) Discussion:
The discussion section of a study synthesizes results, interpreting findings in relation to existing literature. It offers insights into the implications, relevance, and potential applications of research. Engaging in discussions promotes a deeper understanding of studied phenomena and identifies areas for future research.

35) Developing:
Developing refers to the process of creating or enhancing a particular model, theory, or product. In scientific contexts, developing new methodologies or experimental models, such as studying cataractogenesis in vitro, is essential for advancing understanding and improving health outcomes through research.

36) Blindness:
Blindness refers to the loss of vision, which can be caused by various factors, including cataracts. Understanding the mechanisms leading to blindness, particularly in diabetic patients, is crucial for preventative measures and developing effective treatments to mitigate this significant health concern.

37) Flavonoid:
Flavonoids are a class of phytochemicals abundant in many fruits and vegetables, known for their antioxidant properties. They play an essential role in combating oxidative stress and inflammation, potentially lowering the risk of chronic diseases, including diabetes and cataracts. Their study in plant extracts promotes health benefits.

38) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that emphasizes a holistic approach to health using natural remedies, including herbs and diet. Recognizing Ayurvedic practices in research reinforces the significance of traditional knowledge in modern medicine, particularly in the context of plant-based therapeutic studies.

39) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing diseases. This term encompasses various disciplines, including pharmacology and traditional practices like Ayurveda. Continuous research is essential for discovering new treatments, improving existing ones, and enhancing patient care across diverse health conditions.

40) Richness:
Richness in the context of medicinal plants refers to the abundance of beneficial compounds, such as antioxidants and phytochemicals, present in plant extracts. Recognizing the richness of specific plants underscores their therapeutic potentials and supports ongoing research to discover effective treatments for diseases.

41) Bharati:
Bharati is likely a reference to Bharati Vidyapeeth University, an educational institution known for its contributions to research. Acknowledging such institutions highlights their role in advancing knowledge through scientific inquiry and emphasizes collaboration between academia and research in medical sciences.

42) Marathi:
Marathi refers to the language spoken in the Indian state of Maharashtra. In the context of research, it may denote cultural references or traditional practices related to health. Understanding local languages can foster better communication and engagement in community health initiatives and enhance the relevance of traditional knowledge.

43) Species:
Species represents a group of organisms that can interbreed and produce fertile offspring. In research, understanding the species of plants studied is essential for identifying their specific properties and potential therapeutic benefits. This specificity aids in validating traditional uses and exploring new applications in health.

44) Purity:
Purity in scientific terminology refers to the degree to which a substance is free from contaminants. In pharmacological studies, measuring the purity of plant extracts is vital to ensure safety and efficacy in medicinal applications. High-purity extracts are expected to yield more reliable and potent therapeutic effects.

45) Powder:
Powder refers to a finely ground substance, often used in preparing extracts for research or therapeutic applications. In pharmacological studies, plant powders can be utilized to create aqueous or solvent-based extracts, enabling the investigation of their bioactive compounds and health benefits.

46) Sugar:
Sugar generally refers to sweet, soluble carbohydrates used for energy. In the context of cataract studies, excessive sugar, particularly glucose, serves as a risk factor for developing conditions like diabetes and related cataracts, making it vital to understand its biochemical impact on health.

47) Hindi (Himdi):
Hindi is the most widely spoken language in India. In research contexts, referencing Hindi may emphasize the cultural and traditional significance of certain practices, including medicinal uses of plants, enhancing understanding of local knowledge systems and their relevance in contemporary health discussions.

48) House:
House in a scientific context may refer to a facility or environment where research is conducted. It implies a structured setting for experimentation, such as laboratories or medical centers, essential for advancing scientific inquiry and ensuring appropriate conditions for conducting studies.

49) Cham:
Cham often refers to traditional medicines or practices specific to certain cultures, potentially including herbal remedies. In the context of research on plants like Aegle marmelos, recognizing Culturally Appropriate Medicine (Cham) informs studies on efficacy and cultural relevance in health management.

50) Fish:
Fish serves as a model organism in various biological and medical studies due to their physiological characteristics. In models studying diabetic complications or cataracts, understanding the effects of high glucose environments on fish retinal health can draw parallels with human health and disease.

51) Rich (Rch):
Rich in this context describes substances abundant in bioactive compounds beneficial for health. The richness of phytochemicals in plants like Syzygium cumini supports their use in traditional medicine and strengthens the case for further exploration of their preventative and therapeutic roles.

52) Post:
Post refers to the action of disseminating research findings or conclusions after a study has been conducted. It often involves sharing knowledge with broader audiences, contributing to the collective understanding of scientific advancements and supporting collaborative discussions within the research community.

53) Pir:
Peer refers to individuals of similar standing or expertise in a particular field, often involved in the review process. Peer review is crucial for maintaining scientific standards, ensuring that research is scrutinized by qualified experts before it becomes part of the scientific literature.

54) Chan:
Chan, often a reference to an author or researcher, highlights contributions made in scientific literature, particularly within pharmacology or traditional medicinal studies. Recognizing researchers emphasizes collaboration and the importance of their findings in advancing medical knowledge and applications.

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