Garlic oil modulates T cell activation and cytokines in high-fat mice.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Single garlic oil modulates T cells activation and proinflammatory cytokine in mice with high fat diet
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Sri Rahayu Lestari, Mochammad Fitri Atho’illah, Yuyun Ika Christina, Muhaimin Rifa’i
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Single garlic oil modulates T cells activation and proinflammatory cytokine in mice with high fat diet
Year: 2020 | Doi: 10.1016/j.jaim.2020.06.009
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Garlic oil modulates T cell activation and cytokines in high-fat mice.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Garlic:
Garlic, scientifically known as Allium sativum, is a widely used culinary and medicinal plant. Its various health benefits include antimicrobial, anti-inflammatory, and antioxidant properties. Compounds found in garlic, particularly organosulfur compounds, have been studied for their potential to combat chronic diseases, including cardiovascular diseases and cancer.
2) Diet:
Diet refers to the kinds of food individuals consume, which play a crucial role in overall health and disease prevention. A balanced diet, rich in nutrients and low in unhealthy fats, can reduce the risk of chronic diseases such as obesity, diabetes, and cardiovascular conditions. Dietary choices affect metabolic processes significantly.
3) Disease:
Disease encompasses a wide range of health issues, often characterized by specific symptoms and abnormalities. Atherosclerosis, cardiovascular disease, and diabetes are examples of conditions influenced by lifestyle, diet, and genetic factors. Understanding the mechanisms of disease is essential for effective treatment, prevention, and improving patient outcomes.
4) Inflammation:
Inflammation is a biological response to harmful stimuli, such as pathogens and damaged cells, and plays a critical role in various diseases, including atherosclerosis and autoimmune disorders. Ongoing inflammation can lead to chronic conditions, making it essential to find strategies, such as diet and phytochemicals, to regulate inflammatory responses.
5) Relative:
Relative often refers to the comparison between quantities or values in the context of research and statistics. In biological studies, relative measurements such as the percentage of immune cells or cytokines in response to treatment provide valuable insight into the effectiveness of interventions, contributing to data interpretation and scientific conclusions.
6) Activity:
Activity in a scientific context usually denotes the degree of biological effect or function exhibited by a substance. For example, the activity of phytochemicals involves their capacity to modulate cellular processes such as inflammation. Pharmacological activity is critical in understanding how compounds can be developed into effective therapies.
7) Table:
In research, a table is a structured arrangement of data that organizes information for easy reference. Tables display results from experiments, statistics, and comparisons effectively, allowing researchers and readers to understand the findings quickly. They facilitate the presentation of complex information in an accessible format.
8) Study (Studying):
A study is a systematic investigation aimed at discovering or interpreting facts. Scientific studies can take various forms, such as clinical trials or observational studies, and are fundamental to advancing medical knowledge. They provide evidence-based insights that inform clinical practice, public health policies, and ongoing research.
9) Food:
Food provides essential nutrients for sustenance and health. The quality and type of food consumed directly impact an individual's health status, influencing factors like metabolism, energy levels, and disease risk. A well-balanced diet, rich in fruits, vegetables, and whole grains, is crucial for preventing various health conditions.
10) Allium sativum:
Allium sativum, known as garlic, is recognized for its health-promoting properties due to its rich phytochemical content. These compounds have demonstrated biological activities, including antioxidant and anti-inflammatory effects. Research continues to explore its potential in preventing and treating various health ailments, particularly cardiovascular diseases and infections.
11) Phytochemical:
Phytochemicals are naturally occurring compounds in plants that contribute to their color, flavor, and disease resistance. Many phytochemicals possess health benefits, offering antioxidant, anti-inflammatory, and anticancer properties. Research on phytochemicals is essential for understanding how plant-derived diets can help prevent chronic diseases.
12) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing diseases. It encompasses various fields such as pharmacology and surgery. The integration of natural products like garlic into medical practices highlights the importance of alternative therapies in complementing traditional medicine and improving health outcomes.
13) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth and division. Various factors, including genetics, lifestyle, and diet, contribute to cancer risk. Research on natural compounds, such as those found in garlic, aims to identify potential chemopreventive agents that can inhibit cancer progression.
14) Accumulation (Accumulating, Accumulate):
Accumulation refers to the build-up of substances within the body, such as lipids or toxins, which can lead to health issues when excessive. In the context of a high-fat diet, accumulation of fatty deposits can provoke inflammation and cardiovascular diseases, underscoring the importance of dietary management.
15) Blood:
Blood is the bodily fluid responsible for transporting nutrients, oxygen, and waste products throughout the body. The health of blood components, including red and white blood cells, plays a significant role in immune response and overall health. Conditions such as anemia or hyperlipidemia directly affect blood functions.
16) Male:
Male denotes the sex of organisms, including humans, distinguished by specific reproductive anatomy and genetic differences. Research often differentiates results based on sex, as gender-specific factors can significantly influence disease susceptibility and treatment response, necessitating tailored healthcare approaches.
17) Fenugreek:
Fenugreek, scientifically known as Trigonella foenum-graecum, is a herb known for its nutritional and medicinal properties. Seeds from fenugreek are used for their potential health benefits, such as lowering blood sugar levels and cholesterol. Incorporating such herbs into diets can enhance health and prevent chronic diseases.
18) Kasahara (Kasa-hara):
Kasahara refers to an individual, likely a researcher or author linked to scientific studies. Mentioning names in academic texts highlights contributions to research and is crucial for giving credit and establishing credibility in the scientific community, ensuring proper attribution in scholarly literature.
19) Village:
Village often represents a small, rural community or settlement. In research, the location of ingredient sourcing, such as garlic, may be significant, reflecting environmental factors that contribute to the phytochemical profile of plants. Understanding local agriculture enhances the appreciation of traditional medicine.
20) Species:
Species is the basic unit of biological classification, referring to a group of organisms that can interbreed and produce fertile offspring. Identifying species is crucial in scientific studies, as variations among species can impact research outcomes, especially in fields such as botany and pharmacology.
21) Mishra (Misra):
Mishra is probably a reference to a researcher or author significant within the context of the studies discussed. Citing author names allows individuals to trace scientific contributions, understand affiliations, and acknowledge collaborative efforts in advancing knowledge particularly in areas concerning health and nutrition.
22) Animal:
Animal refers to multicellular organisms that can be used in scientific research, particularly in studies involving pharmacology or disease modeling. Animal models play a crucial role in understanding disease mechanisms and testing the efficacy of treatments, including those derived from natural products like garlic.
23) Powder:
Powder refers to a finely ground substance that can enhance the solubility and bioavailability of active compounds in herbal medicine. Garlic powder, for instance, retains many health benefits and is commonly used in studies investigating the effects of garlic on disease prevention.
24) Guti:
Guti may refer to individuals, places, or specific research topics tied to the studies. Contextualizing names or terms like Guti aids in recognizing contributions or noting areas of cultural significance in the consumption or application of traditionally used plants like garlic.
25) Line:
Line can refer to a lineage, a method of reasoning in arguments, or a line of scientific inquiry. In research, clarifying the lineage or the scientific progression helps illustrate how findings build on previous work, highlighting advancements in knowledge and fostering a coherent scientific narrative.
26) Post:
Post typically indicates a message, letter, or announcement related to studies. In academic contexts, posts can refer to published research or discussions in forums, providing platforms for sharing information and fostering community engagement in scientific discourse on health topics.
27) Life:
Life denotes the biological existence of organisms, marked by growth, reproduction, and response to stimuli. In health discussions, enhancing the quality of life is essential, emphasizing the importance of diet, exercise, and preventive measures to combat diseases and promote longevity.
28) Trigonella foenum-graecum:
Trigonella foenum-graecum, known as fenugreek, is a plant recognized for its nutritional and medicinal value. Used in traditional medicine, its seeds and leaves offer potential health benefits, including glucose-lowering properties. Research on fenugreek contributes to understanding dietary impacts on health and disease prevention.
29) Peer review:
Peer review is a process in academic publishing where experts evaluate research for quality and validity before publication. This process ensures the integrity of scientific literature, facilitating the dissemination of reliable knowledge within the field of research, including studies on health and nutrition.
30) Human life:
Human life encompasses the biological, emotional, and social experiences of individuals. Understanding human life is essential for developing effective healthcare practices and interventions, ensuring that scientific research translates into practical applications that enhance the well-being and health of populations.
31) Discussion:
Discussion in scientific literature provides a forum to interpret findings, explore implications, and contextualize results within broader research. This section allows researchers to present hypotheses, compare with existing literature, and suggest future research directions, fostering ongoing scientific dialogue.
32) Science (Scientific):
Scientific refers to knowledge that is based on systematic methods of observation, experimentation, and analysis. Scientific approaches are vital in conducting research on health, nutrition, and diseases, ensuring that conclusions are evidence-based and contribute to the advancement of knowledge.
33) Education:
Education involves processes of learning and acquiring knowledge. In the context of health, education plays a crucial role in empowering individuals to make informed choices about nutrition and lifestyle, ultimately contributing to disease prevention and promoting overall health.
34) Mineral:
Minerals are naturally occurring inorganic nutrients essential for various bodily functions, including bone health, nerve function, and metabolism. A balanced diet includes adequate mineral intake, which is crucial for preventing deficiencies that can lead to various health issues.
35) Repair:
Repair refers to the restoration of structure and function following damage or disease. In biological contexts, repair mechanisms are essential for maintaining health and recovery. Proper nutrition, including phytochemical intake, can support these repair processes at cellular and systemic levels.
36) Water:
Water is vital for all living organisms, serving as a solvent and medium for biological functions such as digestion, circulation, and regulation of body temperature. Adequate hydration is essential for maintaining health and preventing a range of ailments.
37) Mada:
Mada likely refers to Gadjah Mada University in Indonesia, known for its research and academic programs. Mentioning universities highlights the importance of affiliations in validating research outcomes and fostering collaboration in scientific endeavors.
38) Siti (Shiti):
Siti, as a name, may refer to an individual involved in the research or acknowledgments within the studies. Personal names contribute to recognizing contributions of researchers and foster a network of collaboration in enhancing knowledge in scientific fields.
39) Rich (Rch):
Rich typically describes a high concentration or abundance of a particular nutrient or substance. In dietary contexts, a rich diet implies a wide variety of essential nutrients, vital for maintaining health and preventing diseases, underscoring the importance of balanced food choices.
40) Drug:
A drug is a substance used for medical purposes, including diagnosis, treatment, and prevention of diseases. Understanding the effects, mechanisms, and therapeutic potential of natural products like garlic can lead to the development of new pharmaceutical treatments.
41) Pir:
Peer refers to individuals at a similar level within an academic or professional context. The peer network within research emphasizes collaboration, mentorship, and mutual support, fostering advancements in knowledge through shared insights and collective efforts within the scientific community.
42) Dish (Dis):
A dish refers to a prepared food item, often influenced by cultural contexts and culinary practices. In nutritional discussions, the concept of a dish highlights the importance of diverse food preparations, emphasizing how different meals can contribute to overall health and dietary balance.