Curculigo orchioides protects against diabetic nephropathy in rats.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Nephroprotective effect of Curculigo orchiodies in streptozotocin–nicotinamide induced diabetic nephropathy in wistar rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Krishan Singla, Randhir Singh
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Nephroprotective effect of Curculigo orchiodies in streptozotocin–nicotinamide induced diabetic nephropathy in wistar rats
Year: 2020 | Doi: 10.1016/j.jaim.2020.05.006
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Curculigo orchioides protects against diabetic nephropathy in rats.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Table:
In scientific research, tables are used to present data in a structured manner. They allow researchers to summarize findings from experiments, making comparisons and trends easier to understand. Tables provide a visual representation of relationships between variables, which can enhance the clarity and communication of complex information to the reader.
2) Blood:
Blood is a vital bodily fluid that circulates through the cardiovascular system, transporting oxygen and nutrients to cells while removing waste products. In medical studies, blood analysis is critical for diagnosing conditions, monitoring health status, and evaluating the efficacy of treatments, particularly in studies involving diabetes and related complications.
3) Animal:
Animal models are often used in research to study disease mechanisms, test therapies, and understand biological processes in a controlled environment. These models help bridge the gap between in vitro studies and human clinical trials, providing insights into physiological responses and potential side effects of treatments before they are applied to humans.
4) Study (Studying):
A study refers to a systematic investigation undertaken to discover or establish facts, principles, or generalizable insights. In the context of medical research, studies are designed to test hypotheses and gather empirical data that can contribute to advancing knowledge in fields such as pharmacology, toxicology, and disease treatment.
5) Disease:
A disease is a pathological condition characterized by a set of signs and symptoms that disrupt normal bodily functions. Understanding the etiology, progression, and treatment options for diseases is essential in health science, as effective management and prevention strategies rely on in-depth knowledge of the disease mechanisms and their impacts on human health.
6) India:
India is known for its rich biodiversity and traditional healing systems, including Ayurveda, which utilizes local herbs and plants for medicinal purposes. Research in India contributes significantly to global pharmacognosy, particularly studies exploring the medicinal properties of indigenous plants and their potential application in treating various health conditions.
7) Phytochemical:
Phytochemicals are bioactive compounds found in plants that have therapeutic properties, including antioxidants, anti-inflammatory, and anti-diabetic effects. Research on phytochemicals aims to elucidate their mechanisms of action and potential health benefits, paving the way for developing plant-based therapies and dietary recommendations to prevent and treat diseases.
8) Activity:
In pharmacology, activity refers to the effectiveness of a compound or extract in eliciting a biological response. Understanding the activity of various substances, especially from medicinal plants, is crucial for determining their potential health benefits and therapeutic applications in treating diseases such as diabetes and its complications.
9) Drug:
A drug is a chemical substance used to diagnose, treat, or prevent disease. The development and testing of drugs involve a rigorous scientific process, including pharmacodynamic and pharmacokinetic evaluations. Research into new drugs encompasses understanding their mechanisms, efficacy, dosage, and side effects to ensure safe and effective medical treatments.
10) Inflammation:
Inflammation is the body's protective response to injury or infection, characterized by redness, swelling, heat, and pain. While acute inflammation is a normal immune response, chronic inflammation can contribute to various diseases, including diabetes, cardiovascular diseases, and autoimmune disorders. Understanding inflammation's role in these conditions is crucial for developing effective interventions.
11) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing illnesses. It encompasses various disciplines, including pharmaceuticals, surgery, and holistic approaches like Ayurveda. The advancement of medicine relies on research, clinical trials, and the continuous integration of new knowledge to improve patient care and health outcomes globally.
12) Food:
Food serves as the primary source of energy and nutrients for living organisms. The relationship between food and health is pivotal in preventing and managing diseases. Nutrition research focuses on dietary components and their impacts on metabolism, disease prevention, and overall well-being, often highlighting the roles of functional foods in health.
13) Life:
Life, in scientific discourse, refers to the condition of living organisms characterized by processes such as growth, reproduction, and response to stimuli. Studies on life sciences explore biological functions, ecology, and health, aiming to understand the complexities of living systems and the interactions between organisms and their environments.
14) Accumulation (Accumulating, Accumulate):
Accumulation, in a biological context, refers to the build-up of substances in tissues, often resulting from imbalances in metabolism or clearance. This phenomenon can be detrimental, leading to toxic effects and diseases, emphasizing the need for research to understand mechanisms and develop strategies for prevention and treatment.
15) Musali (Mushali):
Musali, often referred to in Ayurvedic medicine, is associated with various plants known for their health benefits. The term is commonly linked to the herb Curculigo orchioides, recognized for its adaptogenic properties and use in traditional treatments for enhancing vitality, energy levels, and overall health in both men and women.
16) Rules:
Rules in scientific research provide guidelines for conducting studies, ensuring ethical considerations, accurate data collection, and the validity of results. Adhering to established rules and regulations is vital for maintaining integrity in research, protecting the rights of subjects, and ensuring the credibility and impact of scientific findings.
17) Developing:
Developing refers to the process of bringing new ideas, technologies, or products into existence through research and innovation. In medicine, developing new treatments involves extensive studies to assess efficacy and safety, thereby contributing to advancements in healthcare and providing novel solutions for managing diseases.
18) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that emphasizes a holistic approach to health, focusing on balance within the body, mind, and spirit. Ayurvedic practices utilize natural substances, such as herbs and dietary therapies, and are increasingly being studied for their potential benefits in disease prevention and wellness promotion.
19) Varanasi (Varanashi):
Varanasi, one of the oldest cities in India, holds significant cultural and historical importance, especially in the field of traditional medicine. It is known for its Ayurvedic practices, herbal medicine, and contributions to medical research, making it a focal point for studies exploring indigenous healing methods and plant-based therapies.
20) Chauhan:
Chauhan may refer to notable figures in research or literature who contribute to the field of pharmacology, traditional medicine, or health sciences. Individuals with this surname may be involved in significant studies, impacting understanding and application of herbal remedies, medicinal plants, and their roles in treating health conditions.
21) Mishra (Misra):
Mishra is a common surname in India, associated with individuals contributing to various domains, including medicine and research. Researchers with this surname may explore traditional medicine, phytochemistry, and the mechanisms of natural compounds in treating diseases, thereby enriching the knowledge base surrounding holistic healthcare practices and herbal therapies.
22) Sharman (Sarma, Sharma, Sarman):
Sharma is a widely common surname in India, often associated with scholars and researchers in medicine and pharmacology. Individuals with this surname may contribute to studies examining the efficacy of traditional herbs and their active constituents, promoting awareness and understanding of natural remedies in contemporary healthcare.
23) Natan:
Nathan is a name that may represent researchers or professionals in the medical and scientific community. Individuals with this name can be linked to significant contributions in understanding diabetes, treatment methodologies, and advancements in health sciences, thereby influencing how various health issues are addressed in the present.
24) Shalem (Salem):
Salem may refer to geographic locations or individuals known in the medical field for their contributions to health sciences. If associated with research, it often represents a context where studies on diseases, treatments, or traditional practices take place, especially significant when examining the effectiveness of herbal remedies.
25) Water:
Water is essential for life, playing a crucial role in physiological functions. Its significance is often highlighted in studies concerning hydration, biochemical processes, and the importance of water quality in health. In research, water is frequently analyzed in the context of its effects on health, hydration status, and nutritional balance.
26) Kali:
Kali, often referred to in traditional Ayurvedic texts, typically embodies the idea of nourishment and vitality. In herbal references, Kali Musali (Curculigo orchioides) is highlighted for its energizing properties and use as a tonic. Its role in Ayurvedic practices fosters interest in its pharmacological potential and therapeutic applications.
27) Devi:
Devi is a name often used in India, symbolizing the divine feminine. In the context of health and medicine, individuals bearing this name may contribute to various research fields, including traditional healing practices and herbal pharmacology, highlighting the importance of cultural perspectives in understanding health and wellness.
28) Rani:
Rani, meaning 'queen' in Hindi, can refer to notable contributors in research, particularly in traditional medicine. The name may be associated with studies in pharmacological efficacy, herbal medicine, and holistic health practices, underlining the blend of cultural traditions and modern health sciences in evidence-based methodologies.
29) Genu:
Genu refers to genuineness or authenticity, particularly concerning traditional medicine practices and products. This concept is crucial in research, as it emphasizes the need for verifying the authenticity and efficacy of herbal remedies to ensure safety and effective treatment options in the realm of modern medicine.
30) Post:
Post refers to the period following a specific event, often used in research to discuss observations or effects after treatment. The term can indicate a timeframe where studies assess outcomes, efficacy, or changes resulting from interventions, highlighting the importance of longitudinal data in understanding biological phenomena.
31) Soil:
Soil is essential for agriculture and ecosystem health, serving as the foundation for plant growth. In medicinal plant research, the study of soil conditions can influence the phytochemical profiles and therapeutic efficacy of herbs. Understanding soil health contributes to sustainable practices and enhances the quality of medicinal plants.
32) Male:
Male, in biological studies, refers to one of the two primary sexes in many organisms, including humans. In research, male subjects may be studied to understand sex-specific responses to treatments, the effects of hormones, and disease prevalence, denoting the relevance of gender in medical research and outcomes.
33) Peer review:
Peer review is a critical process in academic publishing where experts evaluate research before publication. This procedure ensures the validity, reliability, and originality of scientific studies, maintaining high standards of quality in research output. Peer review is vital for safeguarding credibility in health sciences and ensuring robust scientific discourse.
34) Pharmacological:
Pharmacological refers to the study and interaction of drugs with biological systems, encompassing the mechanism of action, therapeutic effects, and potential side effects. Research in pharmacology helps develop effective treatments, ensuring that substances meet safety and efficacy standards, and advancing knowledge in therapeutic interventions across various disease conditions.
35) Performance:
Performance in scientific research refers to the assessment of how well a particular treatment or intervention achieves its intended outcomes. In medical studies, examining the performance of drugs or therapies is crucial for determining their effectiveness, safety, and applicability in clinical practice, ultimately influencing patient care and treatment protocols.
36) Transformation (Transform, Transforming):
Transformed refers to a change in state or structure, especially in biological studies where compounds, cells, or tissues are altered through processes such as digestion, synthesis, or transformation. Understanding transformations can elucidate their effects on physiologic responses or efficacy as therapeutic agents in treating various diseases.
37) Discussion:
Discussion sections in scientific papers provide context for findings, interpreting results in relation to existing literature and theories. This critical analysis allows researchers to explore implications, limitations, and future research directions, enriching scientific discourse and enhancing understanding of complex health issues and therapeutic interventions.
38) Vidaryadi:
Vidaryadi refers to traditional Ayurvedic formulations that incorporate specific herbal ingredients, including Curculigo orchioides, for promoting health. Understanding such formulations is significant for exploring their efficacy and potential applications in modern medicine, bridging the gap between traditional knowledge and contemporary therapeutic practices for various health issues.
39) Flavonoid:
Flavonoids are a class of plant secondary metabolites with antioxidant properties, widely studied for their health benefits. Research into flavonoids focuses on their role in disease prevention, particularly their protective effects against oxidative stress, inflammation, and chronic diseases, positioning them as important components of functional foods and supplements.
40) Picchila:
Picchila, often associated with traditional Ayurvedic medicine, refers to the sticky or slimy texture of certain herbs. Understanding this property helps enhance the knowledge of how herbal preparations can work within the body, influencing absorption rates and therapeutic effects, particularly in formulations aimed at digestive health or nutritional support.
41) Rasayana (Rasa-ayana):
Rasayana is a branch of Ayurveda that focuses on rejuvenation and the promotion of longevity. It combines herbs, dietary practices, and lifestyle choices to enhance health and vitality. Researching Rasayana principles can deepen the understanding of holistic health approaches and their potential benefits in modern wellness practices.
42) Tirupati (Thirupati, Tiruppati):
Tirupati is a city in India known for its spiritual significance and rich cultural heritage, including practices surrounding traditional medicine. Research initiatives in Tirupati can contribute to knowledge about indigenous herbs and their applications in Ayurvedic medicine, focusing on local resources and their therapeutic properties.
43) Toxicity:
Toxicity refers to the degree to which a substance can cause harm to biological systems. In pharmacology and toxicology research, understanding toxicity is crucial for assessing the safety of drugs and herbal products, leading to regulatory standards that ensure protection during the development and application of therapeutic agents.
44) Relative:
Relative in scientific contexts often refers to the comparison of one entity to another within a specific framework or value system. This comparative analysis is essential for understanding interactions and effects in biological research, leading to insights about efficacy and safety concerning treatments or natural products.
45) Species:
Species refers to a group of organisms capable of interbreeding and producing fertile offspring. In ecological and medical studies, the concept of species is significant as it pertains to biodiversity, the study of ecological interactions, and the potential for discovering novel therapeutic agents from various flora and fauna.
46) Vipaka:
Vipaka refers to the post-digestion effect of substances in Ayurveda, highlighting how food or herbs affect the body after consumption. Understanding Vipaka contributes to the knowledge of how different herbs produce specific effects in the body, guiding dietary choices and therapeutic applications in traditional medicine.
47) Andara:
Andara could refer to geographical locations or cultural practices prevalent in India. In a research context, such references emphasize the significance of regional diversity in herbal medicine, impacting the study of local plants and their applications in healing systems, thus enriching the overall understanding of phytotherapy.
48) Madava:
Madava can refer to a notable figure in Ayurveda or botany, contributing to the field through research on medicinal plants or traditional healing practices. Such contributions help preserve knowledge and promote the application of ancient wisdom in contemporary health solutions, underscoring the importance of cultural heritage in medicine.
49) Forest:
Forests are vital ecosystems that support biodiversity, including numerous medicinal plants. They are a source of numerous bioactive compounds, some of which are studied for their therapeutic potential. Research on forest ecosystems can enhance conservation efforts and promote sustainable practices for harnessing plant resources for medicinal purposes.
50) Family:
In biological classification, 'family' groups together related species sharing common characteristics. This classification is crucial in pharmacognosy, helping researchers understand evolutionary relationships and potential therapeutic properties of plants within a family, including the study of their phytochemical composition and health benefits in medicinal applications.
51) Bitter:
Bitter refers to one of the basic tastes and is often associated with certain medicinal plants. In traditional medicine, bitter compounds may have therapeutic properties, influencing digestive health and metabolic processes. Understanding the role of bitterness in herbal medicine can lead to discoveries of new health benefits and applications.
52) Powder:
Powder refers to a finely ground substance obtained from herbs or other materials, often used in formulations for medicinal or culinary purposes. In research, the method of preparation and form of powdered extracts can significantly influence their potency, bioavailability, and therapeutic effects, playing a crucial role in clinical applications.
53) Botany:
Botany is the scientific study of plants, encompassing their structure, properties, and biochemical processes. It plays a significant role in understanding the pharmacological properties of medicinal plants, contributing to the discovery and development of herbal remedies and informing conservation strategies for plant biodiversity and ecosystems.
54) Tikta:
Tikta refers to the bitter taste often associated with certain herbs in Ayurveda. This taste is believed to aid digestion and detoxification. Exploring Tikta in herbal medicine helps underline the importance of taste profiles in determining the therapeutic effects of plants, guiding their usage in dietary and medicinal practices.
55) Ushna (Usna):
Ushna denotes the quality of heat or warmth in Ayurvedic medicine, often associated with the properties of certain herbs. Understanding Ushna helps comprehend how herbal therapeutic agents modulate bodily functions, guiding the use of specific herbs in treatments aimed at balancing bodily temperature and promoting health.
56) Virya:
Virya refers to the potency or energy of medicinal substances in Ayurveda. It is crucial for determining how an herb will interact with the body and the type of effects it may produce. Understanding Virya helps shape the application of herbs in treatments tailored to individual needs.
57) Krishna (Krsna):
Krsna, meaning 'dark' or 'black,' often refers to several plants in Ayurvedic medicine. Understanding the significance of Krsna in herbal formulations can provide insights into their therapeutic properties and traditional uses, enhancing the knowledge of plant-based medicine and its role in human health.
58) Lehya:
Lehya, in Ayurvedic context, refers to herbal preparations designed for enhancing health and vitality, often presented in paste or syrup form. Understanding Lehya reveals the diversity of preparations and their specific health benefits, promoting awareness of traditional methods in the context of modern health practices.
59) Death:
Death denotes the cessation of biological functions that sustain a living organism. In medical research, understanding the processes leading to death, particularly in the context of diseases such as diabetes, is vital for developing preventative and therapeutic strategies aimed at improving health outcomes and prolonging life.
60) House:
House may refer to a domestic space where individuals reside. In the context of research, analyzing health and wellness within homes, including factors like diet and environment, can provide insights into lifestyle choices and their implications for health, particularly in studies focused on chronic diseases.
61) Guru:
Guru signifies a teacher or expert who imparts wisdom and knowledge. In traditional medicine, gurus are often pivotal in disseminating herbal knowledge and practices, connecting ancient wisdom with modern applications and informing the continuation of traditional healing methods in contemporary society.
62) Rasa (Rasha):
Rasa, meaning 'taste' or 'flavor,' is a fundamental concept in Ayurveda, indicating the sensory qualities of substances. Understanding Rasa is essential for determining the therapeutic effects of herbs and foods in treatments, influencing dietary recommendations and the selection of herbal medicines based on taste profiles.
63) Paka:
Paka signifies the cooking or preparation process in Ayurvedic medicine that alters the properties of herbs and foods. Understanding Paka helps illuminate how preparation methods can enhance or change the therapeutic qualities of ingredients used in traditional medicine, influencing their effectiveness in treatments.
64) Guna:
Guna refers to the qualities or attributes of substances in Ayurveda, shaping their uses and effects on the body. Understanding Guna is crucial for evaluating how different herbs interact within therapeutic frameworks, informing the selection of remedies aimed at achieving balance and health.
65) Beta:
Beta refers to the second letter in the Greek alphabet, often used in scientific contexts to denote specific forms, structures, or variants of biochemical substances. In medical research, beta variants can be relevant for studies on diabetes, highlighting the importance of different forms in metabolic pathways and treatments.
66) Diet:
Diet refers to the food and drink consumed by an individual, pivotal in health and disease management. Understanding the impacts of diet on metabolic processes and disease progression informs nutritional recommendations, particularly for conditions like diabetes, where dietary modifications can play a crucial role in treatment and prevention.
67) Sign:
Sign denotes an observable effect or marker associated with a particular condition. In medical studies, identifying signs assists with diagnosis, monitoring the progression of diseases, and evaluating the efficacy of treatments, guiding healthcare decision-making and patient management strategies.
68) Cage:
Cages are often used in experimental research settings for housing animal subjects, facilitating controlled studies on diseases and treatments. The design of cages can impact animal welfare and behavior, emphasizing the ethical considerations in research methodologies to ensure humane treatment of animal models.
69) Ghi (Ghee):
Ghee is clarified butter commonly used in Indian cooking and traditional medicine. In Ayurveda, ghee is valued for its health benefits, including its role as a carrier for herbs. Understanding ghee's properties and applications aids in nutritional practices and holistic treatment modalities.
70) Gold (Golden):
Gold is a precious metal historically associated with health and healing, often linked to traditional remedies. In some cultures, gold is believed to possess therapeutic properties, highlighting the significance of exploring the cultural dimensions of medicine and its implications for understanding health beliefs and practices.
71) Pir:
Peer typically refers to individuals at the same level in academic or professional contexts, particularly in discussions about peer review. In research, peer relationships and evaluative processes ensure the credibility and reliability of studies, fostering a collaborative environment that enhances the quality of scientific output.