Pharmacology of Ativisha, Musta and their substitutes

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Pharmacology of Ativisha, Musta and their substitutes
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Author:

M. Nagarajan, Gina R. Kuruvilla, K. Subrahmanya Kumar, Padma Venkatasubramanian


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Pharmacology of Ativisha, Musta and their substitutes

Year: 2015 | Doi: 10.4103/0975-9476.146551

Copyright (license): CC BY-NC-ND 4.0


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Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Pharmacology of Ativisha, Musta and their substitutes”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to the pharmacological effects exhibited by a substance. In the context of Ayurvedic medicine, the activity of a drug determines its therapeutic use. The document discusses various activities of the plants studied, particularly focusing on antidiarrheal, anti-inflammatory, and antibacterial effects, all of which validate their traditional uses.

2) Species:
Species refers to distinct biological classifications. In this document, various medicinal plants such as Aconitum heterophyllum (Ativisha) and Cyperus rotundus (Musta) are discussed for their therapeutic potential. Understanding the different species helps in recognizing their specific medical applications, as well as their roles as substitutes for rare herbs.

3) Ativisa (Ativisā, Ativiṣā, Ativisha):
Ativisha is the Ayurvedic name for Aconitum heterophyllum, known for its uses in treating diarrhea, fever, and inflammation. The plant is endangered, making its availability a concern. The document highlights Ativisha's properties, pharmacological activities, and its classification under Ayurveda, illustrating the need for sustainable alternatives.

4) Drug:
Drug refers to any substance that has a physiological effect when introduced into the body. In this context, it emphasizes the therapeutic applications of certain plants in Ayurveda. The document examines various herbal drugs, their modes of action, and how they align with traditional medicinal practices.

5) Musta (Mustā, Muṣṭa, Mushta):
Musta is the common name for Cyperus rotundus, used as a substitute for Ativisha in Ayurveda. The document details Musta's medicinal properties, emphasizing its roles in treating various ailments, including fever and diarrhea, showcasing how Ayurvedic practices enable the use of available alternatives to rare plants.

6) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda is an ancient system of medicine originating from India, focusing on holistic healing through natural remedies. The document places significant emphasis on Ayurvedic principles, discussing the classification, usage, and pharmacological activities of various plants within this traditional framework, highlighting its relevance in modern contexts.

7) Antibiotic (Antibacterial):
Antibacterial refers to the ability of a substance to inhibit bacterial growth or kill bacteria. This document reviews the antibacterial properties of various plants, identifying their effectiveness against specific pathogens, underscoring the importance of traditional remedies in addressing bacterial infections and supporting overall health.

8) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing illness. In this context, it reflects the traditional medicinal practices derived from Ayurveda, emphasizing the therapeutic roles of various natural substances, and their functionality and safety in healing and health maintenance.

9) Dravya:
Dravya in Ayurveda refers to substances or materials used for medicinal purposes. This term encompasses various plants, minerals, and formulations discussed in the document, conveying how different dravyas are classified, their properties, and their specific applications in Ayurvedic treatments.

10) Pratinidhi:
Pratinidhi translates to 'substitute' in Ayurveda, often utilized when the original medicinal plant (abhava) is unavailable. The document explores the concept of pratinidhi dravya, specifically discussing the role of various substitutes for endangered species like Ativisha, ensuring the continuation of therapeutic practices.

11) Pharmacological:
Pharmacological pertains to the study of how drugs affect biological systems. The document analyzes the pharmacological profiles of the reviewed plants, emphasizing their various health benefits, mechanisms of action, and supporting the need for empirical validation of traditional medicinal assertions through scientific methods.

12) Aureus:
Aureus likely refers to Staphylococcus aureus, a common bacterium that can cause infections. The document discusses antibacterial activities of various herbs, including their effectiveness against such pathogens, underlining the importance of these traditional plants in treating infections caused by bacteria like Staphylococcus aureus.

13) Kapha:
Kapha is one of the three doshas in Ayurveda, representing the elements of earth and water. It embodies the principles of structure and solidity. The document highlights how various herbs, such as Ativisha and Musta, are classified for their actions on balancing kapha dosha, which is crucial for health.

14) Table:
Table refers to a systematic arrangement of information. In the document, tables are used to summarize the properties, phytochemistry, and pharmacological activities of the discussed species, providing a concise reference for readers and facilitating the comparison of data across the studied plants.

15) Study (Studying):
Study refers to systematic research designed to determine the efficacy and safety of a substance. This document includes various studies that have examined the pharmacological effects of the discussed plants, strengthening the evidence base for their traditional uses in Ayurvedic medicine.

16) Phytochemical:
Phytochemical refers to the bioactive compounds present in plants that contribute to their medicinal properties. The document touches upon various phytochemicals found in the studied species, such as flavonoids, and explores their roles in mediating biological activities, lending scientific support to traditional herbal applications.

17) Flavonoid:
Flavonoids are a class of phytochemicals that provide numerous health benefits, including antioxidant and anti-inflammatory effects. The document mentions flavonoids in the context of examining the chemical composition of plants like Cyperus rotundus, linking their presence to the therapeutic properties attributed to these herbal remedies.

18) Water:
Water serves as a fundamental solvent in herbal medicine, including in the extraction processes of active compounds. Within the context of the document, water may refer to the extraction methods used for preparing herbal remedies, impacting the efficacy and bioavailability of the medicinal properties of plants.

19) Fever:
Fever is a common symptom indicating infection or inflammation. In this document, both Ativisha and Musta are highlighted for their antipyretic properties, providing traditional therapeutic approaches to managing fever, showcasing the role of herbal medicine in treating common health challenges.

20) Cyperus rotundus:
Cyperus rotundus, commonly known as Musta, is a significant herb in Ayurveda known for its multifaceted therapeutic applications. The document illustrates its pharmacological actions, such as anti-inflammatory and antidiarrheal properties, establishing its importance in traditional and modern herbal medicine.

21) Pharmacology:
Pharmacology is the branch of medicine that focuses on drug action and interaction within biological systems. This document applies pharmacological principles to traditional herbs, investigating their properties and actions, thus bridging the gap between conventional Ayurveda and modern scientific inquiry into herbal medicine.

22) Inflammation:
Inflammation is a biological response to harmful stimuli, contributing to various health issues. The document emphasizes the anti-inflammatory properties of several herbs, such as Ativisha and Musta, illustrating their roles in alleviating inflammation in alignment with traditional Ayurvedic practices.

23) Science (Scientific):
Scientific refers to the approach of using systematic methods to acquire knowledge. In this context, the document follows a scientific lens to explore the efficacy of traditional Ayurvedic herbs, validating their uses with empirical evidence and advocating for further research in herbal pharmacology.

24) Caraka (Cāraka, Cārāka):
Caraka refers to one of the prominent ancient texts in Ayurveda, the Caraka Samhita, which outlines classical medical teachings. The document frequently references Caraka to establish traditional therapeutic uses of various herbs, showcasing its importance as a foundational source in Ayurvedic medicine.

25) Dosha (Dosa, Doṣa, Dosā, Doṣā, Ḍosā):
Dosha in Ayurveda refers to the situational balance of bodily energies, specifically vata, pitta, and kapha. The document examines how various herbs interact with doshas, impacting overall health, thus demonstrating the relevance of understanding these energies in herbal healing practices.

26) Katu (Kaṭu, Kātu):
Katu means 'pungent' in Ayurveda, referring to one of the six tastes (rasa). The document discusses the significance of the katu taste in Ativisha and Musta, indicating their roles in digestion and health, emphasizing taste classification's importance in herbal properties.

27) Krimihara (Kṛmihara, Krimi-hara):
Krmihara means 'anthelminthic', referring to the action of expelling intestinal worms. The document emphasizes krimihara properties of herbs like Ativisha and Musta, reinforcing their traditional significance in treating parasitic infections and promoting gastrointestinal health.

28) Nighantu (Nighaṇṭu, Nighamtu):
Nighantu refers to Ayurvedic lexicons that compile information about medicinal herbs, their properties, and uses. In this document, references to Nighantu underline the traditional codification of plant knowledge, supporting its relevance in understanding the therapeutic applications of various species discussed.

29) Toxicity:
Toxicity refers to the degree to which a substance can cause harm to the body. The document mentions toxicity in the context of discussing the safety profiles of various herbs, emphasizing the importance of understanding potential side effects in traditional and modern herbal medicine.

30) Samhita (Saṃhitā, Saṃhita):
Samhita refers to authoritative texts in Ayurveda that compile medical knowledge, teachings, and therapeutic practices. The document references various Samhitas, highlighting their roles in documenting and categorizing medicinal herbs, thus serving as foundational sources for Ayurvedic practitioners.

31) Pungent:
Pungent is a descriptive term for a strong taste, associated with certain herbs. In Ayurvedic context, pungent properties of herbs reflect their ability to stimulate digestion and metabolic processes. The document discusses how the pungent nature of plants like Ativisha and Musta contributes to their therapeutic efficacy.

32) Bitter:
Bitter is one of the six tastes in Ayurveda linked to detoxifying effects and digestive stimulation. The document highlights the bitter properties of Ativisha and Musta, indicating their roles in enhancing digestion, balancing doshas, and promoting health through their traditional applications.

33) Thirst:
Thirst is a sensation indicating the need for hydration. In Ayurveda, the management of thirst is an essential aspect of treatment, and the document mentions how certain herbs like Musta are used to alleviate excessive thirst, reinforcing their significance in holistic health.

34) Cotton:
Cotton may refer to the method of extracting plant compounds, typically used in pharmacological studies, such as in assessing antiinflammatory properties. The document briefly contextualizes cotton in herbal medicine and its role in extraction and formulation processes.

35) Tikta (Tiktā):
Tikta translates to 'bitter' in Ayurveda and represents one of the six tastes influencing digestion and metabolism. The document emphasizes Tikta's significance in Ativisha and Musta, illustrating their medicinal uses associated with this taste, reinforcing the holistic perspective of Ayurvedic medicine.

36) Grahin (Grahi, Grāhī, Grāhi, Grāhin):
Grahi translates to 'absorbing' in Ayurveda and is associated with properties that help in retaining fluids in the body. The document highlights grahi's importance in the context of Musta, reinforcing its traditional use for managing diarrhea and optimizing digestive health.

37) Edema (Oedema):
Edema refers to swelling caused by excess fluid retention. The document discusses the anti-inflammatory properties of certain plants and their potential role in managing edema, emphasizing the need for herbal remedies in reducing such symptoms in traditional medicine.

38) Wall:
Wall likely refers to the scientific classification attributed to Aconitum heterophyllum, as Wall ex Royle. The context supports understanding of this herb’s identity, encouraging proper usage and regulation in traditional and modern herbal practices, emphasizing taxonomic accuracy.

39) Line:
Line may refer to the classification or lineage of plants within botanical taxonomy. In this document, accurate lineage understanding is essential in ensuring proper identification of herbs for therapeutic uses, enhancing the reliability of traditional medicine.

40) Caraka-samhita (Caraka-saṃhitā):
Caraka-samhita, an ancient Ayurvedic text, serves as a primary reference in the document. It presents principles of diagnosis, treatment, and the properties of herbs, reinforcing the foundational role of this text in maintaining the integrity and efficacy of Ayurvedic medicine.

41) Pittadosha (Pittadoṣa, Pitta-dosha):
Pitta-dosha signifies the metabolic energy in Ayurveda, linked to transformation and digestion. The document discusses how various herbs, including Ativisha and Musta, influence the pitta dosha, illustrating their application in restoring balance and promoting health according to traditional practices.

42) Observation:
Observation refers to the process of closely examining and documenting effects or behaviors during research. In the document, observations from various studies underscore the empirical evidence supporting the safety and efficacy of herbal medicines, fostering a scientific understanding of traditional claims.

43) Dravyaguna (Dravyaguṇa, Dravya-guna):
Dravyaguna is a branch of Ayurveda focusing on the characteristics and qualities of substances (dravya). The document emphasizes dravyaguna's role in classifying plants, informing therapeutic uses, and establishing methodologies for evaluating the efficacy of traditional medicines, reinforcing their traditional relevance.

44) Similarity:
Similarity pertains to the shared properties or actions between different substances. The document discusses the similarities between Ativisha and Musta in pharmacological effects, despite differences in their chemical composition, illustrating Ayurvedic principles of substitutability in herbal medicine.

45) Arshoghna (Arśoghna, Arshas-ghna):
Arshoghna translates to 'antihemorrhoid' in Ayurveda, indicating properties that support treatment of hemorrhoids. This document highlights the relevance of certain herbs like Ativisha in managing hemorrhoids, denoting their applications based on traditional ethnopharmacological knowledge.

46) Pittahara (Pitta-hara):
Pittahara refers to properties that alleviate the pitta dosha in Ayurveda. The document discusses how both Ativisha and Musta exhibit pittahara actions, emphasizing their importance in restoring balance to the body’s energies and overall health, according to traditional practices.

47) Bleeding:
Bleeding signifies the loss of blood, which Ayurveda treats using specific herbs. The document emphasizes the necessity of herbal preparations in managing bleeding conditions, showcasing the therapeutic applications of plants like Ativisha, reinforcing their use within traditional medicinal practices.

48) Kashaya (Kāṣāya, Kāśaya, Kāsāya, Kaṣāya, Kaśāya, Kāsaya, Kaṣāyā, Kasāya, Kasaya):
Kashaya, meaning 'astringent' in Ayurveda, describes a taste that can reduce excess moisture and promote drying. The document discusses how kashaya properties in Musta contribute to its medicinal efficacy for treating diarrhea and other conditions related to fluid balance.

49) Disease:
Disease signifies a deviation from normal health. The document outlines how herbal medicine, particularly from Ayurvedic practices, addresses various diseases through natural remedies, illustrating the traditional and modern relevance of plant-based treatments in holistic health.

50) Siddha (Siddhā):
Siddha refers to another traditional Indian system of medicine, similar to Ayurveda. The document mentions Siddha practices to indicate a broader context for understanding herbal applications, underscoring how different indigenous medicinal systems utilize the same plants for therapeutic purposes.

51) Shotha (Śotha, Śoṭha, Soṭhā):
Shotha, meaning 'inflammation' or 'swelling', is a condition addressed in Ayurveda using specific herbal formulations. The document highlights the anti-inflammatory properties of Ativisha and Musta, indicating their relevance in treating shotha through traditional approaches.

52) Ruksha (Rūkṣa):
Ruksha translates to 'dry' in Ayurveda, describing one of the properties of certain herbs. The document highlights ruksha's significance in terms of plant characteristics, particularly as it relates to their actions on doshas, contributing to their therapeutic uses.

53) Dipana (Dīpanā, Dīpana):
Dipana means 'stimulant' and in Ayurveda refers to the ability of herbs to enhance digestive fire or appetite. The document includes dipana as a characteristic of Ativisha and Musta, showcasing their roles in promoting digestion and overall digestive health.

54) Vipaka (Vipāka):
Vipaka refers to the post-digestive transformation of a substance in Ayurveda, influencing its effects within the body. The document emphasizes vipaka’s importance in understanding how herbs like Ativisha and Musta affect the body after digestion, enhancing the therapeutic insights into herbal uses.

55) Castor:
Castor likely refers to castor oil, often used in experimental models for inducing diarrhea. The document mentions castor in relation to studies examining the antidiarrheal efficacy of Ativisha and Musta, providing context for evaluating their effectiveness in controlled settings.

56) Powder:
Powder refers to the form in which many Ayurvedic herbs are prepared for consumption. The document discusses the significance of powdered preparations of Ativisha and Musta, emphasizing their roles in traditional formulations and the ease of administration as therapeutic agents.

57) Indian:
Indian denotes the geographical origin of the plants discussed in the document. It emphasizes the cultural and traditional significance of the herbal remedies within Indian systems of medicine, linking the use of these plants to their historical and regional contexts.

58) Pitta (Pītta, Piṭṭā):
Pitta is one of the three doshas in Ayurveda, responsible for metabolic processes, including digestion. The document explores how various herbs interact with pitta, emphasizing their applications in dietary regulation and treatment to restore balance within the body.

59) Karma (Kārma, Karman):
Karma in Ayurveda refers to the action or effects of a substance on the body. In this document, karma is emphasized in understanding the therapeutic actions of herbs, highlighting how traditional drugs influence bodily functions and contribute to health.

60) Laghu:
Laghu translates to 'light' in the context of Ayurvedic properties, indicating attributes of certain herbs that make them easy to digest. The document illustrates laghu's significance in Ativisha and Musta, connecting these properties to their uses in promoting digestive health.

61) India:
India signifies the cultural and geographical context where Ayurveda originated. In the document, it highlights India's rich tradition of using plants for medicine, ensuring the importance of regional knowledge in both historical and contemporary herbal practices.

62) Kumar (Kumār):
Kumar appears to refer to Subrahmanya Kumar K, an author mentioned in the document. His contributions to the study and understanding of abhava-pratinidhi dravya, or substitute herbs in Ayurveda, underline the growing academic interest in integrating traditional practices with modern scientific research.

63) Blood:
Blood refers to the fluid that circulates in the body, crucial for various physiological processes. The document discusses the relevance of certain herbs in managing blood-related disorders, reinforcing the role of traditional medicine in promoting circulatory health.

64) Diet:
Diet signifies the food patterns and nutritional intake crucial for health. The document emphasizes the impact of herbal remedies on diet regulation, showcasing the interplay of nutrition and medicinal plants in maintaining overall well-being within Ayurvedic practices.

65) Fire:
Fire represents the digestive fire (Agni) in Ayurveda, symbolizing metabolism and transformation. The document associates various herbs with enhancing Agni, illustrating how they promote digestion and overall health, highlighting the holistic nature of Ayurvedic medicine.

66) Rheumatoid arthritis:
Rheumatoid arthritis is an autoimmune condition characterized by joint inflammation. The document suggests that certain herbal remedies may possess anti-inflammatory properties useful in managing symptoms, showcasing the relevance of traditional medicine in addressing chronic inflammatory conditions.

67) Burning sensation:
Burning sensation is described as a symptom often related to inflammation or irritation. The document highlights how various herbs are used to soothe such sensations, emphasizing their properties that may alleviate discomfort in Ayurvedic practice.

68) Pharmacotherapeutics:
Pharmacotherapeutics refers to the study of the therapeutic uses of drugs. The document integrates pharmacotherapeutics with traditional herbal medicine, examining the efficacy and safety of various plants within the framework of established scientific knowledge, illustrating a modern approach to ancient practices.

69) Trishnanigrahana (Tṛṣṇānigrahaṇa, Trishna-nigrahana):
Trishnanigrahana translates to 'alleviating thirst' in Ayurveda. The document discusses how specific herbs like Musta can address excessive thirst, showcasing their importance in maintaining fluid balance and overall health in traditional medicinal practices.

70) Shadangapaniya (Ṣaḍaṅgapānīya, Shadanga-paniya):
Shadangapaniya is a herbal formulation in Ayurveda utilized for digestive and gastrointestinal issues. The document refers to this formulation, linking it to the therapeutic applications of components like Musta and Ativisha in aiding digestion within traditional frameworks.

71) Stanyashodhana (Stanyaśodhana, Stanya-shodhana):
Stanyashodhana refers to therapeutic actions concerning breast milk quality and digestion. The document indicates the relevance of specific herbs, including Musta, in addressing nursing issues, emphasizing their importance within Ayurvedic maternal care practices.

72) Tiktaskandha (Tikta-skandha):
Tikta-skandha refers to a category of bitter-tasting herbs in Ayurveda. The document highlights its association with plant classifications, elucidating the significance of such categorizations in determining the therapeutic applications of various species in traditional medicine.

73) Tastelessness:
Tastelessness indicates a condition where food and drink lack flavor, often associated with health issues. The document mentions herbs used to combat tastelessness, showcasing traditional remedies that support digestion and rejuvenation through enriching the sensory experience of food.

74) Transmission:
Transmission refers to the passage of information or influence, likely relating to the mechanisms through which herbal properties exert their effects. The document examines how various pharmacological activities are transmitted through bioactive compounds in the plants discussed, enhancing their therapeutic relevance.

75) Shothahara (Śothahara, Shotha-hara):
Shotha-hara means ‘anti-inflammatory’ in Ayurveda, emphasizing properties that relieve swelling and inflammation. The document elaborates on how certain herbs possess shotha-hara qualities, supporting their inclusion in traditional treatments for inflammatory conditions.

[Note: The above list is limited to 75. Total glossary definitions available: 118]

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Discover the significance of concepts within the article: ‘Pharmacology of Ativisha, Musta and their substitutes’. Further sources in the context of Science might help you critically compare this page with similair documents:

Dravyaguna, Cyperus rotundus, Aconitum heterophyllum, Treatment of diarrhea, Liquid preparation, Ayurvedic literature, Antioxidant activity, Immunomodulatory activity, Hepatoprotective activity, Antibacterial properties, Anthelmintic activity, CNS activity, Phytochemical composition, Antiplatelet activity, Antipyretic properties, Abhava Pratinidhi Dravya, Antiinflammatory properties, Insecticidal activity, Antidiarrhoeal properties, Hypoglycemic properties, Bioactivity of plant.

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