Anxiolytic, sedative, hypnotic effects of Morinda citrifolia extract
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Anxiolytic, sedative, and hypnotic activities of aqueous extract of Morinda citrifolia fruit
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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Sridharan Kannan, Shanti Manickam, Meher Ali RajaMohammed
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Anxiolytic, sedative, and hypnotic activities of aqueous extract of Morinda citrifolia fruit
Year: 2014 | Doi: 10.4103/0975-9476.131738
Copyright (license): CC BY-NC-ND 4.0
Download the PDF file of the original publication
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Anxiolytic, sedative, hypnotic effects of Morinda citrifolia extract”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the measurable actions or behaviors exhibited by the subjects in the study. In this context, it specifically pertains to the anxiolytic, sedative, and hypnotic effects of Morinda citrifolia, which were quantitatively assessed through various experiments involving locomotor activity and aggression reduction in rodents.
2) Animal:
Animal indicates the subjects of the experimental study, specifically the male albino mice used to assess the effects of Morinda citrifolia. Their responses to the extracts, through behavioral observations and various models, provide insights into the efficacy of the herbal remedy as a potential anxiolytic or sedative.
3) Study (Studying):
Study denotes the structured research conducted to evaluate the effects of Morinda citrifolia on anxiety and related behaviors in rodents. This study aims to establish scientific evidence for the traditional use of the fruit as a medicinal agent, contrasting it with established drugs like diazepam.
4) Drug:
Drug in this context refers to substances used to induce specific physiological effects, particularly diazepam, used as the standard comparator in assessing the extract of Morinda citrifolia. The study compares the herbal extract’s efficacy against this well-known anxiolytic medication in animal models.
5) Anxiety:
Anxiety refers to the psychological state being explored in the study. It assesses how Morinda citrifolia may mitigate symptoms of anxiety, typically characterized by increased aggression and stress responses in the isolation-induced model used for evaluating the effects of the extract.
6) Male (Mālē):
Male specifies the gender of the albino mice used in the experiments. The choice of male subjects may relate to standardized research protocols or biological factors influencing behavior and hormonal differences, which are relevant in anxiety studies and pharmacological effects assessment.
7) Water:
Water is significant in the study as it acts as the control agent against which the effects of Morinda citrifolia and diazepam are measured. It represents the baseline condition, allowing for a clearer comparison of the activites induced by the various treatments administered.
8) Medicine:
Medicine encompasses the broader context of the study, highlighting the intent to validate the traditional medicinal use of Morinda citrifolia. It connects the findings to the field of therapeutic interventions for anxiety and implies the potential for herbal remedies in modern medical practices.
9) Cage (Cāge):
Cage refers to the controlled environment in which the mice were isolated for behavioral assessment. It signifies a critical aspect of the experimental design, allowing researchers to observe aggression and anxiety behaviors in a controlled setting while minimizing external influences.
10) Madurai:
Madurai is the location where the study was conducted, serving as the institutional base for animal research. This geographic context adds credibility to the study, indicating institutional ethics compliance and possible regional significance of Morinda citrifolia in traditional medicine.
11) Indian:
Indian relates to the cultural and historical significance of Morinda citrifolia (noni) in traditional medicine practices in India. It emphasizes the local usage and knowledge surrounding the fruit, providing a contextual backdrop for the research into its therapeutic properties.
12) India:
India represents the country where the study was conducted and highlights the geographical source of Morinda citrifolia. It ties into the examination of indigenous herbal remedies and supports the investigation of their pharmacological relevance in modern contexts.
13) Pharmacology:
Pharmacology refers to the scientific discipline that studies drugs and their effects on biological systems. This field is pertinent to the study, which seeks to establish the pharmacological effects of Morinda citrifolia, thereby contributing to both traditional knowledge and modern medicinal practices.
14) Vinayakar (Vināyakar, Vinayagar):
Vinayagar refers to Sri Manakula Vinayagar Medical College, which is associated with the research. This acknowledgment emphasizes the collaboration involved in the study and recognizes the support from academic institutions in advancing knowledge about herbal medicines and their pharmacological properties.
15) Quality:
Quality in this context pertains to the assessment of the Morinda citrifolia fruit used in the study. The assurance of high-quality materials ensures valid and reliable results, as the effectiveness of herbal extracts can significantly vary based on their source and preparation.
16) Account:
Account indicates the documentation of findings and the need for transparency in research. It stresses the importance of recording and presenting results accurately, which is essential for reproducibility, peer review, and the advancement of scientific knowledge in herbal medicine.
17) Nature:
Nature refers to the inherent characteristics and effects exhibited by the Morinda citrifolia extract. Understanding the nature of its anxiolytic, sedative, and hypnotic properties is crucial for contextualizing its potential utility in treating anxiety disorders within traditional and modern medical paradigms.
18) Food:
Food signifies the potential classification of Morinda citrifolia as a dietary supplement rather than a pharmaceutical drug. This perspective broadens the implications of the study, as it suggests the fruit may serve as a natural aid for anxiety when incorporated into dietary practices.
19) Diet:
Diet pertains to the nutritional regimen that includes the consumption of Morinda citrifolia. The study indicates that the extract could function as a beneficial dietary addition for individuals experiencing anxiety, thereby merging the concepts of nutrition and mental health in holistic wellness strategies.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Anxiolytic, sedative, hypnotic effects of Morinda citrifolia extract’. Further sources in the context of Science might help you critically compare this page with similair documents:
Central nervous system, Clinical studies, Institutional animal ethics committee, Food supplement, Anxiolytic effect, Neurotransmitter levels, Sedative effect, Hypnotic effect, Spontaneous locomotor activity, Morinda citrifolia fruit, Isolation-induced aggression, Herbal Remedie.