Brahma rasayana effects on chromosomal and sperm abnormalities in mice
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Studies on Brahma rasayana in male swiss albino mice: Chromosomal aberrations and sperm abnormalities
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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K. P. Guruprasad, Roshan Mascarenhas, P. M. Gopinath, K. Satyamoorthy
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Studies on Brahma rasayana in male swiss albino mice: Chromosomal aberrations and sperm abnormalities
Year: 2010 | Doi: 10.4103/0975-9476.59826
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Brahma rasayana effects on chromosomal and sperm abnormalities in mice”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Rasayana (Rasa-ayana, Rasāyana, Rāsāyana):
Rasayana refers to a branch of Ayurveda focused on rejuvenation therapies. It is believed to enhance health, longevity, and vitality, particularly in older adults. The practices incorporate various plant-based formulations that are designed to harmonize body, mind, and spirit, achieving equilibrium in the body's biological systems.
2) Animal:
In the context of this study, 'animal' pertains to the use of male Swiss albino mice as experimental subjects. Mice serve as a common model in biological research due to their physiological and genetic similarities to humans, enabling insights into potential effects of herbal treatments on health and disease.
3) Table:
The term 'table' denotes the organized presentation of data or findings in the study. Tables help convey results clearly, allowing for comparison between control and treatment groups. In this research, tables summarize chromosomal aberrations, sperm data, and mitotic indices, aiding in the visualization of the study's outcomes.
4) Brahma (Brahmā, Brāhma):
Brahma refers to Brahma Rasayana, an Ayurvedic formulation used for rejuvenation and cognitive enhancement. This formulation is rich in herbal ingredients aimed at improving mental clarity, reducing anxiety, and enhancing overall health. Its diverse phytochemical composition contributes to its purported health benefits, including antioxidant and immunomodulatory effects.
5) Toxicity:
Toxicity in this context relates to the potential harmful effects of Brahma Rasayana on biological systems, particularly concerning genetic material and reproductive health. The study assesses genotoxic potential through analyses involving chromosomal aberrations, sperm abnormalities, and overall health metrics, ensuring that the formulation does not produce adverse effects.
6) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda is an ancient Indian holistic healing system emphasizing balance between body, mind, and spirit. It incorporates natural approaches to health, focusing on maintaining harmony with the body's rhythms. Ayurveda utilizes herbal medications, lifestyle changes, and treatments, including rejuvenation practices, to promote well-being and prevent illness.
7) Medicine:
Medicine in this study refers to the application of Ayurvedic principles, particularly Brahma Rasayana, for therapeutic purposes. Understanding the effects of herbal formulations as medicinal agents expands the potential for alternative treatment options. The research explores the safety and efficacy of Brahma Rasayana in addressing age-related health issues.
8) Study (Studying):
This study investigates the genotoxic effects of Brahma Rasayana using an in vivo mouse model. It aims to provide scientific validation for traditional herbal medicine practices by examining multiple health indicators, reinforcing the importance of research in understanding the safety profile and therapeutic benefits of Ayurvedic treatments.
9) Drug:
In this context, 'drug' pertains to the formulation of Brahma Rasayana as a therapeutic product derived from natural sources. It emphasizes the role of herbal preparations as potential pharmaceutical agents, highlighting the significance of examining their safety, usage, and physiological impacts on living organisms.
10) Emblica officinalis:
Emblica officinalis, commonly known as Indian gooseberry or Amla, is a key ingredient in Brahma Rasayana. It's recognized in Ayurveda for its potent antioxidant and immune-boosting properties, playing a crucial role in the formulation's effectiveness against oxidative stress and enhancing overall health functionalities.
11) Terminalia chebula:
Terminalia chebula, also known as Haritaki, is another significant herb used in Brahma Rasayana. It is renowned for its therapeutic properties, including digestive benefits, detoxification, and rejuvenation. Its inclusion in the formulation contributes to the overall efficacy and health-promoting characteristics attributed to the rasayana.
12) Activity:
Activity in this study refers to the functional outcomes observed after administering Brahma Rasayana, particularly related to reproductive health and genetic integrity. It encompasses the study of physiological effects such as changes in sperm count, mitotic index, and cellular health, categorized under the broader impact of the treatment.
13) Disease:
Disease refers to deviations from normal physiological functions that the Ayurvedic formulation aims to prevent or manage. The study explores how Brahma Rasayana may support health against age-related diseases and dysfunctions by evaluating its effect on cellular health, which may ultimately contribute to better disease resistance.
14) Vaidya:
Vaidya denotes a traditional practitioner of Ayurveda, skilled in the practice of herbal medicine and holistic healing. The term emphasizes the importance of expert guidance in the administration of Ayurvedic treatments like Brahma Rasayana, ensuring appropriate application and understanding of individual health needs.
15) Medhya (Medhyā, Meḍhyā):
Medhya refers to a classification in Ayurveda focused on cognitive enhancement and mental health. Brahma Rasayana is categorized as a Medhya Rasayana, indicating its intended effects on improving memory, learning capabilities, and anxiety management, thus emphasizing the role of mental wellness in overall health.
16) House:
In this context, 'house' pertains to the animal housing at Manipal University, where the mice were maintained under standard conditions. Adequate housing is crucial for ethical research practices, ensuring that experimental animals are in a controlled environment conducive to promoting their health and well-being.
17) Shala (Sālā, Sāla, Śala, Śālā, Śāla, Sala):
Sala refers to Arya Vaidya Sala, the entity providing the Brahma Rasayana formulation used in the study. It signifies the importance of sourcing high-quality herbal preparations from esteemed institutions, reinforcing the credibility and efficacy of the Ayurvedic products used in scientific research.
18) Arya (Ārya, Āryā):
Arya pertains to Arya Vaidya Sala, an organization rooted in the practice of Ayurveda, emphasizing the quality and traditional knowledge behind the formulations provided. Their commitment to Ayurvedic science supports the authentic use of herbal preparations in contemporary research and medicine.
19) Food:
Food in the study context relates to the normal diet mixed with Brahma Rasayana, highlighting the role of nutrition in administering herbal treatments. Incorporating supplements into conventional diets ensures ease of administration, retaining the dietary habits of the test subjects while enabling the effects of the formulation to be studied.
20) Sign:
Sign in this research conveys the evidence or indicators of the effects of Brahma Rasayana observed in the study results. Statistical analysis reveals whether the observed changes in parameters such as sperm abnormalities and mitotic indices are significant, thereby substantiating the formulation's effects.
21) Cinnamomum zeylanicum:
Cinnamomum zeylanicum, commonly known as cinnamon, is among the ingredients in Brahma Rasayana. This spice is valued not only for its flavor but also for its medicinal properties, including anti-inflammatory and antioxidant effects that contribute to the holistic benefits of the formulation in promoting health.
22) Tinospora cordifolia:
Tinospora cordifolia, referred to as Guduchi or Giloy, is an important herb in Ayurveda noted for its immunomodulatory properties. Its inclusion in Brahma Rasayana reinforces the formulation's potential to enhance immune function, support resilience against diseases, and promote overall vitality.
23) Solanum xanthocarpum:
Solanum xanthocarpum, or yellow nightshade, is a component of Brahma Rasayana recognized for its therapeutic properties. This herb is believed to contribute to the formulation's effectiveness in balancing bodily functions and addressing various health issues, showcasing Ayurveda's extensive use of plant diversity in medicine.
24) Phyllanthus emblica:
Phyllanthus emblica, also known as Indian gooseberry or Amla, is noted for its high vitamin C content and potent antioxidant properties. It plays a significant role in Brahma Rasayana, enhancing its ability to mitigate oxidative stress and offering beneficial effects on overall health and vitality.
25) Glycyrrhiza glabra:
Glycyrrhiza glabra, also called licorice root, is included in the formulation of Brahma Rasayana. Known for its soothing properties and ability to support digestive health, licorice root contributes to the overall effectiveness of the rasayana in promoting longevity and wellness.
26) Withania somnifera:
Withania somnifera, commonly referred to as ashwagandha, is a prominent herb in Ayurveda. It is known for its adaptogenic properties, helping the body manage stress and enhancing resilience, contributing to the cognitive and restorative benefits attributed to Brahma Rasayana.
27) Cyperus rotundus:
Cyperus rotundus, or nutgrass, is included in the Ayurvedic formulation Brahma Rasayana. It is recognized for its treatment of digestive ailments and is thought to improve nutrient absorption and overall health, showcasing the integrative approach of Ayurveda towards holistic health and preventive medicine.
28) Solanum indicum:
Solanum indicum is a component of Brahma Rasayana, known for its medicinal properties in traditional medicine. This plant may provide various health benefits, enhancing the overall efficacy of rasayana formulations in promoting vigor and addressing age-associated health concerns.
29) Santalum album:
Santalum album, also known as sandalwood, is part of Brahma Rasayana's diverse herbal ingredients. Valued for its calming properties, sandalwood contributes not only to the formulation's fragrance but also to its therapeutic effects on mental and emotional health, harmonizing the body's holistic needs.
30) Curcuma longa:
Curcuma longa, commonly known as turmeric, is a key ingredient in Brahma Rasayana. Renowned for its anti-inflammatory and antioxidant properties, turmeric enhances the health benefits of the formulation, supporting the body's natural defenses against age-related ailments and promoting overall well-being.
31) Piper longum:
Piper longum, or long pepper, is included in Brahma Rasayana for its beneficial medicinal properties. It is traditionally used to enhance digestion and respiratory health, contributing to the formulation's diverse effects on improving physical and mental vitality in Ayurveda.
32) Desmodium gangeticum:
Desmodium gangeticum, known as Salparni, is a vital constituent of Brahma Rasayana recognized for its health-promoting properties. Used in Ayurveda to support reproductive health and longevity, it underscores the formulation's focus on restoring balance and improving overall health.
33) Asparagus racemosus:
Asparagus racemosus, commonly called Shatavari, is well-known in Ayurveda for its adaptogenic and reproductive health benefits. Its inclusion in Brahma Rasayana enhances the formulation's nurturing qualities, especially for female health, contributing to the overall efficacy of rejuvenation therapies.
34) Tribulus terrestris:
Tribulus terrestris is included in Brahma Rasayana for its reputation as a tonic, particularly for male reproductive health. It is believed to enhance vitality and stamina, showcasing the formulation's multifaceted approach to promoting well-being across different age groups.
35) Oroxylum indicum:
Oroxylum indicum, known as the trumpet tree, is part of Brahma Rasayana's herbal complex. It is recognized for its antioxidant and anti-inflammatory properties, reinforcing the formulation's protective effects on health and its role in maintaining vitality and mental clarity.
36) Ricinus communis:
Ricinus communis, or castor oil plant, is another herb present in Brahma Rasayana. It is traditionally utilized for its therapeutic properties, contributing to the formulation's ability to enhance digestion and promote overall health and well-being.
37) Gmelina arborea:
Gmelina arborea, commonly known as gmelina or beechwood, is included in Brahma Rasayana for its restorative benefits. Its adaptation in Ayurvedic practices emphasizes the formulation's role in promoting longevity and vitality through the use of diverse plant resources.
38) Acorus calamus:
Acorus calamus, or sweet flag, is a traditional herb used in Brahma Rasayana believed to improve cognitive functioning. It highlights the focus on enhancing mental faculties in Ayurveda, supporting memory and concentration alongside physical rejuvenation.
39) Embelia ribes:
Embelia ribes, known as false black pepper, is another key ingredient in Brahma Rasayana recognized for its health benefits. Its inclusion strengthens the formulation's potential in promoting longevity and vitality by harnessing the diverse phytochemical properties of plants.
40) Mandukaparni (Maṇḍūkaparṇī, Manduka-parni, Mamdukaparni):
Mandukaparni, also known as Centella asiatica, is utilized in Brahma Rasayana for its cognitive-enhancing effects. It contributes to improving memory and mental clarity, aligning with the formulation's therapeutic focus on rejuvenation and mental health.
41) Radiotherapy:
Radiotherapy is a cancer treatment involving the use of radiation. The study suggests that Brahma Rasayana may have beneficial effects as an adjunct therapy during cancer treatments, potentially supporting overall health and recovery in patients undergoing such interventions.
42) Mudgaparni (Mudgaparṇī, Mudga-parni):
Mudgaparni refers to the herb Phaseolus trilobus used in Brahma Rasayana. Emphasizing the importance of diverse plant-based ingredients, it contributes to the formulation's ability to improve nutritional status and overall well-being in individuals.
43) Shalaparni (Śālaparṇī):
Shalaparni is a herb, Desmodium gangeticum, included in Brahma Rasayana. Known for its role in promoting reproductive health and vitality, it signifies Ayurveda’s holistic approach in combining various herbs for comprehensive therapeutic effects on human health.
44) Agnimantha (Agni-mantha, Agnimamtha):
Agnimantha, known scientifically as Clerodendron premnos, is part of Brahma Rasayana. This herb is traditionally used for its health-promoting properties, contributing to the overall efficacy of the formulation in rejuvenating body and mind as a holistic approach in Ayurveda.
45) Rishabhaka (Ṛṣabhaka):
Rishabhaka, or Bambusa arundinacea, is included in Brahma Rasayana for its reputed health benefits. It signifies the diverse range of herbs utilized in Ayurvedic formulations, each selected for specific therapeutic properties, enhancing the collective effects on health and wellness.
46) Mashaparni (Māṣaparṇī, Masha-parni):
Mashaparni refers to Teramnus labialis, a herb within Brahma Rasayana. Its inclusion emphasizes Ayurveda's focus on utilizing various plant sources for enhancing physical health and vitality, showcasing the holistic philosophy behind rasayana therapies.
47) Erandamula (Eranda-mula, Eraṇḍamūla):
Erandamula, or Ricinus communis, is featured in Brahma Rasayana. It highlights the tradition of incorporating plants with specific health benefits into Ayurvedic formulations, further emphasizing the importance of diverse herbal resources in promoting longevity and wellness.
48) Toxicology:
Toxicology pertains to the study of the adverse effects of substances on living organisms. This study examines the genotoxic potential of Brahma Rasayana, adhering to rigorous scientific protocols and highlighting the safety evaluation necessary for traditional medicines used in contemporary health practices.
49) Drowsiness:
Drowsiness indicates a condition involving a lack of alertness or energy, which is countered by Rasayana therapies. Brahma Rasayana is intended to rejuvenate and restore energy, alleviating drowsiness and enhancing overall health, particularly in aging individuals.
50) Narasimha (Narasiṃha, Nārasiṃha, Narasingha, Nara-simha):
Narasimha refers to another Ayurvedic formulation or rasayana known for its rejuvenating effects. Similar to Brahma Rasayana, it is part of the traditional quest for longevity and vitality through herbal enhancements.
51) Shatavari (Śatāvarī, Satāvarī):
Shatavari, or Asparagus racemosus, is recognized for its role in women's reproductive health and vitality. Its presence in formulations like Brahma Rasayana highlights the emphasis on gender-specific benefits and the broad focus of Ayurveda on well-being.
52) Punarnava (Punarnavā, Punarṇava, Punar-nava):
Punarnava, known scientifically as Boerhavia diffusa, is an important herb in Ayurveda known for its renoprotective properties. Its inclusion in formulations supports detoxification processes and recovery, aligning with Ayurvedic principles on rejuvenation and health.
53) Kantakari (Kaṇṭakārī, Kamtakari, Kantakāri):
Kantakari, or Solanum xanthocarpum, is a medicinal herb in the Ayurvedic tradition, noted for aiding respiratory health. Its role in Brahma Rasayana underscores the importance of supporting multiple bodily functions through synergistic herbal combinations in traditional formulations.
54) Pesticide:
Pesticides are chemicals used to eliminate pests, but they can pose risks to health. Toxicology evaluates potential adverse effects from such substances, emphasizing the importance of understanding and mitigating the risks stemming from exposure in various contexts, including the implications for herb-based formulations.
55) Gambhari (Gambhārī):
Gambhari, or Gmelina arborea, is a significant herb utilized in Brahma Rasayana. Its health-promoting properties promote vitality and rejuvenation, illustrating the potency of Ayurvedic formulations that draw upon the medicinal qualities of multiple indigenous plants.
56) Shyonaka (Śyonāka, Śyoṇāka, Syonāka):
Shyonaka, or Oroxylum indicum, is another important component of Brahma Rasayana, contributing to the formulation's health benefits. Its usage aligns with Ayurvedic principles of combining various herbs for a synergistic approach to health and rejuvenation.
57) Gokshura (Gokṣura, Go-kshura):
Gokshura, or Tribulus terrestris, is included in Brahma Rasayana for its energizing properties. This herb is known for supporting vitality, particularly male reproductive health, enhancing the multidimensional benefits contained within the Ayurvedic formulation.
58) Sitopala (Sita-upala, Sitopalā):
Sitopala, also known as sugar candy, is used in Ayurvedic practices for its sweetness and soothing properties. It not only improves palatability but also plays a role in balancing the therapeutic actions of harsher tasting herbs in formulations like Brahma Rasayana.
59) Learning:
Learning in the context of the study refers to the cognitive enhancement potential of Brahma Rasayana. By supporting mental clarity and memory, the formulation aligns with Ayurvedic principles of promoting not just physical, but also cognitive health, especially in aging individuals.
60) Kshaudra (Kṣaudra):
Kshaudra, or milk, is an essential ingredient in Brahma Rasayana. Its nutrient-rich profile enhances the formulation's overall benefits, underscoring the importance of dairy in Ayurvedic diets for supporting health and vitality through nourishment.
61) Vidanga (Viḍaṅga, Vidamga):
Vidanga, known scientifically as Embelia ribes, is featured in Brahma Rasayana for its digestive and health-promoting benefits. Its inclusion reflects Ayurveda's holistic approach, ensuring that the formulation is fortified with natural substances known for enhancing digestive health and overall vitality.
62) Brihati (Bṛhatī):
Brihati refers to Solanum indicum, a herb within the formulation of Brahma Rasayana. Its health benefits emphasize the need for diverse plant sources in achieving comprehensive health and wellness, aligning with traditional knowledge and modern research into its efficacy.
63) Pippali (Pippalī, Pīppalī, Pippalin):
Pippali, or long pepper, is a notable herb in Brahma Rasayana with a reputation for enhancing digestive health and respiratory function. Its role emphasizes the importance of combining herbs with complementary properties to maximize health benefits within Ayurvedic formulations.
64) Quality:
Quality in this context pertains to the standards and evaluations to ensure the efficacy and safety of herbal formulations. Rigorous quality assessments are essential to validate the effectiveness of traditional medicines like Brahma Rasayana in modern therapeutic applications.
65) Anxiety:
Anxiety is a common mental health concern that Brahma Rasayana aims to alleviate. With ingredients recognized for their calming properties, the rasayana formulation aligns with Ayurveda's holistic approach, addressing both physical and emotional health in its rejuvenating effects.
66) Siddha (Siddhā):
Siddha refers to another traditional medicinal practice, similar to Ayurveda. This highlights the rich diversity of Indigenous healing systems in India, reflecting an integrated approach to human health that emphasizes harmony, balance, and the natural utilization of resources.
67) Kanaka (Kanakā, Kānaka):
Kanaka, or Atropa belladona, is a herb considered in Ayurveda for its roles related to health and healing. Its utilization in preparations like Brahma Rasayana underlines the extensive knowledge base within traditional systems regarding beneficial plant properties.
68) Rajani (Rajanī, Rājanī):
Rajani refers to Curcuma longa or turmeric, a significant component of Brahma Rasayana. Its inclusion is largely due to its recognized anti-inflammatory and health-promoting properties, demonstrating the application of culturally relevant herbs in holistic health practices.
69) Kshara (Kṣāra):
Kshara refers to the alkaline preparations used in various contexts within Ayurveda. Its relevance signifies the exploration and discussion of diverse medicinal forms used in conjunction with herbs like those found in Brahma Rasayana to bolster healing practices.
70) Dhatri (Dhātrī, Dhātṛ, Dhātri):
Dhatri, or Phyllanthus emblica, lists among the potent ingredients in Brahma Rasayana. The herb's enrichment with antioxidants supports its role in preventing oxidative stress and promoting longevity, reflecting traditional dietary practices aimed at sustaining health over time.
71) Hridya (Hṛdya):
Hridya translates to heart-protective in Ayurveda, emphasizing formulations and practices focused on cardiovascular health. The breadth of formulations suggests a multidimensional approach in Ayurveda, where several herbs may offer cumulative benefits across physiological systems.
72) Patala (Pāṭalā, Paṭala, Pātāla, Pāṭala, Pātala):
Patala, or Pterospermum suaveolens, is included in Brahma Rasayana. Its traditional properties emphasize the extensive range of medicinal plants known in Ayurveda, each selected for their significant contributions to promoting health and well-being.
73) Pathya (Pathyā, Pāṭhya):
Pathya refers to health-promoting ingredients or dietary guidelines in Ayurveda. Their relevance in Brahma Rasayana underscores the holistic view of nourishment and wellness, reflecting an integrated approach to achieving balance and vitality in life.
74) Cancer:
Cancer is a critical health concern where Brahma Rasayana might play a supportive role, particularly when used adjunctively in therapies like radiotherapy. Understanding its potential benefits signals the interest in integrating traditional herbal medicine with contemporary treatments for holistic health solutions.
75) Sharman (Śarma, Sarmā, Sarma, Sharma, Śarman):
Sharma refers to a researcher in the literature provided, indicating previous studies that examined the protective effects of natural ingredients found in formulations like Brahma Rasayana. Their contributions underscore the foundation of scientific inquiry into the efficacy and safety of Ayurvedic practices.
[Note: The above list is limited to 75. Total glossary definitions available: 100]
Other Ayurveda Concepts:
Discover the significance of concepts within the article: ‘Brahma rasayana effects on chromosomal and sperm abnormalities in mice’. Further sources in the context of Ayurveda might help you critically compare this page with similair documents:
Rasayana therapy, Brahma Rasayana, Antioxidant activity, Sperm count, Medhya Rasayana, Ayurvedic Drug, Immunomodulatory functions, Reproductive toxicity, Experimental animal, Chromosomal aberration, Sperm abnormalities, Mitotic index, Genotoxic potential, Antioxidant function, Toxicology testing, Anti-angiogenic properties.