A review of pharmacological action of vishaghna dravyas from charakokt mahakashay in drug-induced nephrotoxicity w.s.r. to garavishajanya shotha
Journal name: Journal of Ayurveda and Holistic Medicine
Original article title: A review of pharmacological action of vishaghna dravyas from charakokt mahakashay in drug-induced nephrotoxicity w.s.r. to garavishajanya shotha
The Journal of Ayurveda and Holistic Medicine (JAHM) promotes Ayurvedic scientific research by offering a platform for in-depth exploration and integration of its principles into modern healthcare. JAHM is owned and published by Atreya Ayurveda Publications. Atreya Ayurveda Publications engaged in scientific publications on Ayurveda in the form of print books and ebooks since 2007.
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MANASI SUBHASH BRID
Journal of Ayurveda and Holistic Medicine:
Full text available for: A review of pharmacological action of vishaghna dravyas from charakokt mahakashay in drug-induced nephrotoxicity w.s.r. to garavishajanya shotha
Year: 2019 | Doi: 10.70066/jahm.v7i2.59
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Kidney being a major organ of excretion, is susceptible to the damage caused due to variety of toxins such as xenobiotics, drugs, environmental toxins etc. Nephrotoxicity is impairment of renal function which occurs due to adverse effects of these toxins on kidney. Oxidative stress is implicated as one of the mechanisms of drug induced nephrotoxicity. Drug induced nephrotoxicity (DIN) can be correlated with the concept of gara visha in Ayurveda. Shotha is one of the important manifestations found in gara visha as well as drug induced nephrotoxicity. Vishaghna dravyas from Charakokt Mahakashays possess shothaghna, raktashodhak, tridoshashamak and mutral properties. Also, these dravyas have been reported for antioxidant and nephroprotective potential. Hence, these vishaghna dravyas from Charakokt Mahakashays can be useful in garavishajanya shotha as well as drug induced nephrotoxicity. This review article is an attempt to discuss the role of vishaghna dravyas as antioxidant and gara vishaghna in oxidative stress induced nephrotoxicity with special reference to garavishajanya shotha.
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Garavisha, Oxidative stress, Chronic renal failure, Drug-Induced Nephrotoxicity, Acute Tubular Necrosis, Acute Interstitial Nephritis, Acute Renal Failure, Nephroprotective Potential, Toxin Exposure, Vishaghna dravya, Antioxidant.