Ayurveda management for dhatukshaya janya vandhyatva w.s.r to low anti-mullerian hormone- a systematic review and meta-analysis

Summary of article contents:

The low antimullerian hormone is a severe problem in the present scenario in women seeking infertility. It is the leading cause of unable to conceive or delayed conception due to poor quality of ovum. The main factors behind these are mainly due to the westernization of lifestyle, deviating from the traditional way of living. Endocrinedisrupting chemical contributes to premature ovarian senescence. In Ayurveda, it can be compared with Dhatukshaya janya Vandhyatva Agni of dhatu nirmana affected by Annavaha Srotodushti due to intake of ati matra aahara, akala & ahita aahara. Dhatu’s dhatwagni supplies the necessary source to succeeding tissues, enhancing their ability to clone. By using Ayurveda formulations, ovarian ovum quality can be increased to be available for conception for healthy progeny. Intake of Kapikacchu & Talmakhana churna with sharkara & ksheera act as Dhatu vardhaka . Kapikacchu & ksheera has shukra Janaka pravartaka property, which improves quality and quantity with nourishes shukra dhatu in females. This medication altogether works on the microenvironment of cells and thus prevents Apoptosis. Kapikacchu has been reported to enhance fertility in preclinical studies; however, there is a shortage of literature on its effect on the function of the female reproductive system. Kapikacchu seed extract has the potential to enhance fertility by increasing serum levels of FSH and LH, which in turn increases the number of oocytes released at ovulation, possibly through its antioxidant properties. Talmakhana effectively restored the Haematological parameters, serum iron and serum protein and normalized the microcytic, anisocytosis and hypochromic RBCs, as it mainly works on Rasa dhatu nirvana. Keywords: Firelog, Snigdha , L-dopa, Follicles, Steroidogenesis INTRODUCTION Dhatukshaya janya Vandhyatva is one of the six types of Vandhyatva described by Acharya Harita