Effect of stress in the formation of ama w.s.r. to gut-brain axis

Summary of article contents:

Ayurveda, a holistic system of medicine from ancient India, considers Manas (the mind) one of the fundamental components of health and disease. Manas Bhavas refer to emotional and psychological factors such as anger, fear, greed, grief, and other emotional trauma that can disturb the balance of Doshas ( Vata, Pitta, and Kapha ) and Agni (digestive fire) within the body. When Agni is weakened, partially digested food ( Ama ) accumulates, impairing cellular function and contributing to disease. Stress, a prevalent modernday phenomenon, significantly impacts Agni by altering gut motility, secretion of digestive enzymes, and microbiota composition. The gutbrain axis, a bidirectional communication network between the gut and the central nervous system, is crucial in regulating stress responses and gastrointestinal functions. Chronic stress disrupts this axis, leading to dysregulation of the gut microbiota, increased intestinal permeability, and inflammation—factors known to promote Ama formation, according to Ayurveda . This abstract highlight the potential for interdisciplinary collaboration between Ayurveda and modern medicine to address the complex interplay of stress, gut health, and Ama formation. By understanding and managing stress through the lens of the gutbrain axis, healthcare providers can develop more effective preventive and therapeutic approaches tailored to individual needs, promoting overall wellbeing and vitality. Keywords: Ama, Manas Bhavas, Stress, Gut-Brain Axis INTERNATIONAL AYURVEDIC MEDICAL JOURNAL Tanushree Gite