A randomized controlled trial to compare the effect of jathyadi ghrita with povidone iodine ointment in dushtavrana

Summary of article contents:

Dushtavrana is a commonly encountered problem faced in surgical practice. The presence of Dushtavrana worsens the condition of the patient with different complications which may become fatal and lifethreatening. Good wound healing with minimal scar formation and pain is the prime motto of every surgeon. Many formulations have been in use for centuries. One of these is a polyherbal drug, Jathyadi Ghrita . The present study compares the effect of Jathyadi Ghrita and Povidone Iodine ointment on relief in signs and symptoms of Dushtavrana. Clinically diagnosed 34 Dushtavrana patients were divided into groups A and B. Group A (Trial group) managed with Jathyadi Ghrita . Group B (the control group) was managed using the Povidone Iodine ointment application. The study duration was 28 days in both groups, with 17 participants in each group. Assessment was done on 0 th, 7 th,14 th ,21 st and 28 th day. The data obtained was statistically analysed and interpreted. The assessment was done on the 0 th,7 th,14 th,21 st and 28 th day. The collected data were subjected to statistical analysis using appropriate statistical methods. Frequency and percentages were calculated for qualitative variables, while mean and SD were calculated for quantitative variables. Nonparametric methods were employed to analyse the data. The Wilcoxon signedrank test was used to assess the significant effect before and after treatment within each group. The Mann Whitney U test was used to compare two groups based on before and after treatment values. P value less than 0.05 is statistically significant. All analyses were carried out with the help of the software SPSS 23.0. Statistically significant changes were noted in pain and itching sensation by management with Jathyadi Ghrita in Dushtavrana compared to Povidone Iodine ointment. Considering all observations, statistical analysis was done, and conclusions were drawn. The study results statistically reveal that Jathyadi Ghrita shows better results than Povidone Iodine ointment in managing pain, itching sensation, burning sensation, ulcer size, and discharge. Thus, the null hypothesis is rejected, and the alternate hypothesis is accepted . Keywords: Dushtavrana , Jathyadi Ghrita , Povidone Iodine ointment INTRODUCTION Ayurveda is a timetested health system with a vast scope of trials to prove certain principles and the therapeutic effects of medicines