A comparative clinical study to evaluate the efficacy of jeerakadi lepa and mukhakantikara lepa in the management of vyanga(melasma)

Summary of article contents:

Vyanga is one of the important diseases pertaining to hyper Pigmentation disorders. It is considered Kshudrarogas , which occurs mainly due to vitiation of Vata , Pitta and Rakta . Vyanga presence of Neeruja , Tanu , Shyavavarnayuktamandala on Mukhapradesha . Melasma is a hyperpigmented macular lesion that develops slowly and symmetrically over the malar area, bridge of the nose, forehead and upper lips, more commonly seen in females than males. Hyperpigmentation is due to increased melanocytes activity in epidermal and dermal layers. Brhajakapitta is mainly related to Varna of twacha . So, Pitta is the main culprit to cause Vyanga . Here, all Jeerakadi Lepa's and Mukhakantikara Lepa's ingredients are Pittashamaka , Varnyakara , Raktaprasadaka , Twakprasadaka , Kandughna , Kusthaghna . Methods: A Randomized comparative clinical trial is adopted. In Group A were given Jeerakadi lepa with milk for 30 days application (once in a day).In Group B were given Mukhakantikara lepa with water for 30 days application (once in a day) .Total duration of study was carried out for 45 days. Results: By applying the Friedman test and Wilcoxon sign rank test for within the group it was statistically significant. The Mann Whitney U test is applied between the groups the results showed statistically not significant. Hence, we conclude that we reject null hypothesis H 0 and accept the alternate hypothesis H 2. i.e H 2 : Jeerakadilepa is more effective than Mukhakantikara lepa in the management of Vyanga . Keywords: Vyanga, Melasma , Mukhakantikara lepa, Jeerakadi lepa