A review of naturally derived compounds showing anticancer activity
Journal name: International Ayurvedic Medical Journal
Original article title: A review of naturally derived compounds showing anticancer activity
The International Ayurvedic Medical Journal (IAMJ) is a peer-reviewed scientific publication dedicated to Ayurveda. It aims to integrate Ayurvedic concepts with modern scientific understanding, offering a comprehensive source of validated knowledge for both the modern Ayurvedic community and the broader medical fraternity.
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Nandkishor Borse
Narkhede Yogesh Dnyandeo
International Ayurvedic Medical Journal:
(Publishing full-length original papers and reviews on ayurveda)
Full text available for: A review of naturally derived compounds showing anticancer activity
Year: 2023
Copyright (license): CC BY-NC-ND 3.0
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Summary of article contents:
Cancer is the second leading cause of death after Cardiovascular disease Globally. Determining the goals of treatment and palliative care is an important first step, and health services should be integrated and peoplecentered. The primary goal is generally to cure cancer or to considerably prolong life. Improving the patient's quality of life is also an important goal. Findings newer treatment options for cancer treatments with attention towards naturallyderived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. Current treatment of cancer includes Chemotherapy, radiation, and surgery. But all of these treatments are well known for the stress patient has to suffer during and after treatment. So lots of work is being done of finding naturally occurring anticancer drugs. This article reviews different types of naturally derived compounds showing anticancer activity. Despite the progress in the field of cancer research, both developing and developed countries are in the grip of this deadly disease, and still, there is a need to discover and develop anticancer therapeutic agents. It has long been recognized that natural products represent the richest source of high chemical diversity, providing the basis for the identification of novel scaffold structures that serves as starting points for rational drug design. Several medicinal plant species and their phytochemicals inhibit the progression and development of cancer. Out of these, there are four major structural classifications of plantderived anticancerous compounds viz., Vinca alkaloids, Epipodophyllotoxin lignans, Taxane diterpenoids, and Camptothecin quinolone alkaloid derivatives discuss here. Keywords: Phytochemical, anticancer, Vinca alakaloid, Taxane diterpenoids, Camptothecin quinolone alkaloid, Epipodophyllotoxin lignans
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Chemotherapy, Phytochemical, Natural product, Therapeutic agent, Palliative care, Plant kingdom, Anticancer activity, DNA topoisomerase, Cancer research, Toxic side effects, Cancer cell proliferation, Vinca alkaloid.