Anatomical changes in janusandhigata vata w.s.r to knee osteoarthritis

Summary of article contents:

Asthi (bone) is the main seat of vata doshain the body responsible for different body movementssandhi, whereas Shleshak kapha present in during movement. The shleshak kapha is white, nature. These characters are similar with the characters of synovial fluid present within the joints. Due to aggravation of vata dosha in Sandhi result a diseased condition known as “affected the condition is known as “Janusandhigata Vata”, driti sparsa (feeling of air filled balloon),shopha (swelling), stabdata (stiffness), bone) etc. These symptoms are somehow similar to the symptoms of “knee Osteoarthritis”. Osteoarthritis is a joint failure, where all structures of a joint have undergoes pathological changes l sclerosis of subchondral bony plate, growth of osteophytes at the joint margin and weakness of the muscles bridging the joint. Whenever Knee joint is affected called as “knee osteoarthritis”. and overuse of joint there is an injurious static compression state, can stimulate the reduction of proteoglycans from the superficial zone (layer) of articular cartilage and damage the collagen network. This condition leads to fibrillation/damage of hyaline cartilage present in joint forming surfaces of bones. Chondrocytes present in the articular cartilage can respond to direct biomechanical perturbation by modulating synthetic activity or by increasing the production of inflammatory cytokines. On the other han by altered bone remodeling processes leading to sclerosis. Osteophytes are also produced like this. In Osteoarthritis the viscosity of synovial fluid is decreased because of decreased production and polymerization hyaluronic acid, which is probably the major lubricant of synovial fluid due to water binding ability. This condition greatly affects the joint movements followed by pain and crepitus Keywords: Janu Sandhi, Janu Sandhigata Vata INTRODUCTION Janu Sandhi INTERNATIONAL AYURVEDIC MEDICAL JOURNAL ISSN