Pharmaceutical and analytical study of dhatriavleha

Summary of article contents:

Avleha is one of the semisolid forms of Ayurvedic medicine. It is prepared from herbs with addition of Jaggery or Sugar. As these products last for longer time and also they are easily palatable there is an increasing demand for Avlehas in the market today. Because of its sweet taste many Avlehas are used in pediatric practice, looking for its increasing demand the standardization i.e. setting standards for Avleha is a need now a days. Absence of reference standards for compound formulations is a need on the way towards standardization. The present study was aimed for pharmaceutical and analytical study of dhatriavleha. Analytical study provides us the objective parameters for standardization. It helps in understanding and interpretation of a drug and its structure. Dhatriavaleha formulation mentioned in Charak Chikitsasthana which is useful in Pandu, Kamala, and Halimak is taken for present study . DhatriAvleha includes draksha, sunthi, pippali, vanshlochan, yashtimadhu, madhu, sharkara. Three batches of Dhatriavaleha were prepared to develop Standard Operating Procedure. In Analytical study prepared Dhatriavaleha was tested for organoleptic parameters and physicochemical parameters like loss on drying, total sugar content, alkaloid content, total ash value, acid insoluble ash value, methanol soluble extractive value, water soluble extractive value, pH value. HPLC was done. Values of Physicochemical parameters can be taken as measures for quality control of Dhatriavaleha. Keywords: DhatriAvleha , Analytical Study, HPLC INTRODUCTION Bhaishajya Kalpana is a branch of Ayurveda which involves a perfect combination of herbal drugs as well as minerals in various types of preparations. The word Bhaishajya means relating to medicine i.e. Bhaishajya and Kalpana means formulation. Ayurveda considers each and everyherb in the universe to be a Bhaishajya but the thing is, it should be taken in proper quantity and combinations. Preparations in Bhaishajya Kalpana have more peculiarities about its quantity in any of the formulations. It mainly focuses on the quantity and quality of the drugs and thus is growing need INTERNATIONAL AYURVEDIC MEDICAL JOURNAL International Ayurvedic Medical Journal, ( ISSN: 2320 5091) (October, 2017) 5(10) PHARMACEUTICAL AND ANALYTICAL STUDY OF DHATRIAVLEHA Sulakshana B. Varpe 1 , Shital D. Shirgure 2 , Shweta R. Helge 3 1 MD Rasashastra Associate professor, 2 MD Rasashastra, 3 PG scholar RasashastraRasashastra & BK Dept. College of Ayurveda &Research Centre, Nigdi, Pune, Maharashtra, India Email: hshweta 04@gmail.com ABSTRACT Avleha is one of the semisolid forms of Ayurvedic medicine. It is prepared from herbs with addition of Jaggery or Sugar. As these products last for longer time and also they are easily palatable there is an increasing demand for Avlehas in the market today. Because of its sweet taste many Avlehas are used in pediatric practice, looking for its increasing demand the standardization i.e. setting standards for Avleha is a need now a days. Absence of reference standards for compound formulations is a need on the way towards standardization. The present study was aimed for pharmaceutical and analytical study of dhatriavleha. Analytical study provides us the objective parameters for standardization. It helps in understanding and interpretation of a drug and its structure. Dhatriavaleha formulation mentioned in Charak Chikitsasthana which is useful in Pandu, Kamala, and Halimak is taken for present study . DhatriAvleha includes draksha, sunthi, pippali, vanshlochan, yashtimadhu, madhu, sharkara. Three batches of Dhatriavaleha were prepared to develop Standard Operating Procedure. In Analytical study prepared Dhatriavaleha was tested for organoleptic parameters and physicochemical parameters like loss on drying, total sugar content, alkaloid content, total ash value, acid insoluble ash value, methanol soluble extractive value, water soluble extractive value, pH value. HPLC was done. Values of Physicochemical parameters can be taken as measures for quality control of Dhatriavaleha. Keywords: DhatriAvleha , Analytical Study, HPLC INTRODUCTION Bhaishajya Kalpana is a branch of Ayurveda which involves a perfect combination of herbal drugs as well as minerals in various types of preparations. The word Bhaishajya means relating to medicine i.e. Bhaishajya and Kalpana means formulation. Ayurveda considers each and everyherb in the universe to be a Bhaishajya but the thing is, it should be taken in proper quantity and combinations. Preparations in Bhaishajya Kalpana have more peculiarities about its quantity in any of the formulations. It mainly focuses on the quantity and quality of the drugs and thus is growing need INTERNATIONAL AYURVEDIC MEDICAL JOURNAL International Ayurvedic Medical Journal, ( ISSN: 2320 5091) (October, 2017) 5(10) PHARMACEUTICAL AND ANALYTICAL STUDY OF DHATRIAVLEHA Sulakshana B. Varpe 1 , Shital D. Shirgure 2 , Shweta R. Helge 3 1 MD Rasashastra Associate professor, 2 MD Rasashastra, 3 PG scholar RasashastraRasashastra & BK Dept. College of Ayurveda &Research Centre, Nigdi, Pune, Maharashtra, India Email: hshweta 04@gmail.com ABSTRACT Avleha is one of the semisolid forms of Ayurvedic medicine. It is prepared from herbs with addition of Jaggery or Sugar. As these products last for longer time and also they are easily palatable there is an increasing demand for Avlehas in the market today. Because of its sweet taste many Avlehas are used in pediatric practice, looking for its increasing demand the standardization i.e. setting standards for Avleha is a need now a days. Absence of reference standards for compound formulations is a need on the way towards standardization. The present study was aimed for pharmaceutical and analytical study of dhatriavleha. Analytical study provides us the objective parameters for standardization. It helps in understanding and interpretation of a drug and its structure. Dhatriavaleha formulation mentioned in Charak Chikitsasthana which is useful in Pandu, Kamala, and Halimak is taken for present study . DhatriAvleha includes draksha, sunthi, pippali, vanshlochan, yashtimadhu, madhu, sharkara. Three batches of Dhatriavaleha were prepared to develop Standard Operating Procedure. In Analytical study prepared Dhatriavaleha was tested for organoleptic parameters and physicochemical parameters like loss on drying, total sugar content, alkaloid content, total ash value, acid insoluble ash value, methanol soluble extractive value, water soluble extractive value, pH value. HPLC was done. Values of Physicochemical parameters can be taken as measures for quality control of Dhatriavaleha. Keywords: DhatriAvleha , Analytical Study, HPLC INTRODUCTION Bhaishajya Kalpana is a branch of Ayurveda which involves a perfect combination of herbal drugs as well as minerals in various types of preparations