Comparative therapeutic effect of guduchi rasayana and simhanada guggulu in amavata

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Objective: To compare the therapeutic efficacy of Guduchi Rasayana and Simhanada Guggulu in patients suffering from Amavata. Study design: An open randomized comparative clinical trial with pre and posttest design. Study Selection: 30 patients suffering from Amavata /Rheumatoid Arthritis were selected for the study from SDM Ayurveda Hospital, Udupi, during the period November 2016 to March 2017. Intervention: Group A: Patients were administered with Eranda taila 20 ml in empty stomach for a period of seven days, followed by Guduchi Rasayana 12 cap OD in empty stomach for 30 days. Group B: Patients were administered with Simhanada Guggulu 1 g tid for period of 30 days. Main Outcome of Measures: The response of the intervention was assessed in both the groups before the treatment and after the treatment with the scoring pattern and the results were analyzed statistically using paired‘t’ test within the group and unpaired ‘t’ test between the groups Results: Theobservations noted after the treatments were statistically significant in subjective and objective criteria in both the groups. Guduchi Rasayana showed better results on overall improvement with 33.3% of major improvement, 46.6% of moderate improvement and 20% of mild improvement. Whereas Simhanada Guggulu shown 13.3 % of major improvement, 53.3 % had moderate improvement and 33.3 % had mild improvement. Conclusion: Both the Groups were found to be efficacious in relieving the cardinal symptoms of Amavata and improving in functional ability, whereas Guduchi Rasayana showed comparatively better improvement Keywords: Amavata, Rheumatoid Arthritis, Guduchi Rasayana, Simhanada Guggulu. INTRODUCTION INTERNATIONAL AYURVEDIC MEDICAL JOURNAL International Ayurvedic Medical Journal, ( ISSN: 2320 5091) (October, 2017) 5(10) COMPARATIVE THERAPEUTIC EFFECT OF GUDUCHI RASAYANA AND SIMHANADA GUGGULU IN AMAVATA Brinda G M 1 , G Shrinivasa Acharya 2 , Nishanth K Pai 3 1 Final year PG scholar, 2 Professor & HOD, 3 Assistant Professor,Dept. of PG studies in Kaya Chikitsa and Manasa Roga Shree Dharmasthala Manjunatheshwara college of Ayurveda, Udupi, Karnataka, India Email :dr.brindagm@gmail.com ABSTRACT Objective: To compare the therapeutic efficacy of Guduchi Rasayana and Simhanada Guggulu in patients suffering from Amavata. Study design: An open randomized comparative clinical trial with pre and posttest design. Study Selection: 30 patients suffering from Amavata /Rheumatoid Arthritis were selected for the study from SDM Ayurveda Hospital, Udupi, during the period November 2016 to March 2017. Intervention: Group A: Patients were administered with Eranda taila 20 ml in empty stomach for a period of seven days, followed by Guduchi Rasayana 12 cap OD in empty stomach for 30 days. Group B: Patients were administered with Simhanada Guggulu 1 g tid for period of 30 days. Main Outcome of Measures: The response of the intervention was assessed in both the groups before the treatment and after the treatment with the scoring pattern and the results were analyzed statistically using paired‘t’ test within the group and unpaired ‘t’ test between the groups Results: Theobservations noted after the treatments were statistically significant in subjective and objective criteria in both the groups. Guduchi Rasayana showed better results on overall improvement with 33.3% of major improvement, 46.6% of moderate improvement and 20% of mild improvement. Whereas Simhanada Guggulu shown 13.3 % of major improvement, 53.3 % had moderate improvement and 33.3 % had mild improvement. Conclusion: Both the Groups were found to be efficacious in relieving the cardinal symptoms of Amavata and improving in functional ability, whereas Guduchi Rasayana showed comparatively better improvement Keywords: Amavata, Rheumatoid Arthritis, Guduchi Rasayana, Simhanada Guggulu. INTRODUCTION INTERNATIONAL AYURVEDIC MEDICAL JOURNAL International Ayurvedic Medical Journal, ( ISSN: 2320 5091) (October, 2017) 5(10) COMPARATIVE THERAPEUTIC EFFECT OF GUDUCHI RASAYANA AND SIMHANADA GUGGULU IN AMAVATA Brinda G M 1 , G Shrinivasa Acharya 2 , Nishanth K Pai 3 1 Final year PG scholar, 2 Professor & HOD, 3 Assistant Professor,Dept. of PG studies in Kaya Chikitsa and Manasa Roga Shree Dharmasthala Manjunatheshwara college of Ayurveda, Udupi, Karnataka, India Email :dr.brindagm@gmail.com ABSTRACT Objective: To compare the therapeutic efficacy of Guduchi Rasayana and Simhanada Guggulu in patients suffering from Amavata. Study design: An open randomized comparative clinical trial with pre and posttest design. Study Selection: 30 patients suffering from Amavata /Rheumatoid Arthritis were selected for the study from SDM Ayurveda Hospital, Udupi, during the period November 2016 to March 2017. Intervention: Group A: Patients were administered with Eranda taila 20 ml in empty stomach for a period of seven days, followed by Guduchi Rasayana 12 cap OD in empty stomach for 30 days. Group B: Patients were administered with Simhanada Guggulu 1 g tid for period of 30 days. Main Outcome of Measures: The response of the intervention was assessed in both the groups before the treatment and after the treatment with the scoring pattern and the results were analyzed statistically using paired‘t’ test within the group and unpaired ‘t’ test between the groups Results: Theobservations noted after the treatments were statistically significant in subjective and objective criteria in both the groups. Guduchi Rasayana showed better results on overall improvement with 33.3% of major improvement, 46.6% of moderate improvement and 20% of mild improvement. Whereas Simhanada Guggulu shown 13.3 % of major improvement, 53.3 % had moderate improvement and 33.3 % had mild improvement. Conclusion: Both the Groups were found to be efficacious in relieving the cardinal symptoms of Amavata and improving in functional ability, whereas Guduchi Rasayana showed comparatively better improvement Keywords: Amavata, Rheumatoid Arthritis, Guduchi Rasayana, Simhanada Guggulu