Systemic lupus erythomatous - a case study in ayurvedic setting

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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterizedby the production of auto antibodies resulting from the dysfunction of T cells, B cells and dendritic cells. Ninetypercents of patients are women of child bearing years. People of both sexes, all ages and all ethnic groups are susceptible. Here we are reporting a case of SLE of a 26 year old female patient. The possible understanding of the case in terms of Ayurveda and a therapeutic protocol with promising result has been discussed. Keywords: SLE, autoantibodies, dendritic cells How to cite this URL: Dr. Rituyadav Et Al: Systemic Lupus Erythomatous - A Case Study In Ayurvedic Setting. International Ayurvedic medical Journal {online} 2016 {cited 2016 July} Available from:http://www.iamj.in/posts/images/upload/3081_3085.pdf SYSTEMIC LUPUS ERYTHOMATOUS - A CASE STUDY IN AYURVEDIC SETTING Dr. RituYadav 1 , Dr. J.P. Singh 1 , Dr. Ajay Kumar Sahu 3 , Dr. Pankaj Sharma 4 1 MD Scholar, 3 Assistant Professor, 4 MD Scholar PG Department of Kayachikitsa, NIA,Jaipur, Rajasthan, India 2 Associate Professor, PG Department of Kayachikitsa, IMS, BHU, Uttar Pradesh India INTRODUCTION SLE is autoimmune diseases in whichorgans and cells undergo damage mediated by tissue binding auto antibodies and immune complexes 1 SLE affects 2 to 8 persons per 100,000 in United States. Most cases occur in women of childbearing years. African, Asian and Native Americans are three times more likely to develop than whites Etiology is unknown.Mostprobable causes are Genetic influence, Hormonal imbalance, Environmental factors and certain medications. The diagnosing signs and symptoms aremalarrash,discoid rash,serositis, oral ulcers,arthritis, photo sensitivity blood problems (leukopenia),renal Failure,ANA (+),immunologic Problems,neurologic Problems(cerebritis) 2.Under clinical manifestationsmusculoskeletal manifestations are-Polyarthralgia with morning stiffness,Arthritis, Swan neck fingers,Ulnar deviation,Subluxation with hyper laxity ofjoints Cardiopulmonary manifestationsare Tachypnea, Pleurisy, Dysrhythmias, Accelerated CAD, Pericarditis Renalmanifestations are Lupus nephritis ranging from mild proteinuria to glomerulonephritis.Primary goal in treatment is slowing the progression Nerological manifestationsare generalized/focal seizures, peripheral neuropathy, cognitive dysfunction, disorientation, memory deficits and psychiatric symptoms Hematologic manifestations are formation of antibodies against blood cells, anemia, leucopenia, thrombocytopenia, coagulopathy. Incidence of systemic manifestations of SLE are Systemic fatigue, malaise, fever, anorexia, weight loss-95%,Musculoskeleton- 95%,Cutaneous-60%,Haematological- 85%,Neurological-60%,Cardiopulmonary- 60%,Renal-30 to 50%,Gastrointestinal- 40%,Thrombosis-15%,Ocular-15% 3 Case report - A 26 year old female patient Case Report International Ayurvedic Medical Journal ISSN:2320 5091 ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterizedby the production of auto antibodies resulting from the dysfunction of T cells, B cells and dendritic cells. Ninetypercents of patients are women of child bearing years. People of both sexes, all ages and all ethnic groups are susceptible. Here we are reporting a case of SLE of a 26 year old female patient. The possible understanding of the case in terms of Ayurveda and a therapeutic protocol with promising result has been discussed. Keywords: SLE, autoantibodies, dendritic cells How to cite this URL: Dr. Rituyadav Et Al: Systemic Lupus Erythomatous - A Case Study In Ayurvedic Setting. International Ayurvedic medical Journal {online} 2016 {cited 2016 July} Available from:http://www.iamj.in/posts/images/upload/3081_3085.pdf SYSTEMIC LUPUS ERYTHOMATOUS - A CASE STUDY IN AYURVEDIC SETTING Dr. RituYadav 1 , Dr. J.P. Singh 1 , Dr. Ajay Kumar Sahu 3 , Dr. Pankaj Sharma 4 1 MD Scholar, 3 Assistant Professor, 4 MD Scholar PG Department of Kayachikitsa, NIA,Jaipur, Rajasthan, India 2 Associate Professor, PG Department of Kayachikitsa, IMS, BHU, Uttar Pradesh India INTRODUCTION SLE is autoimmune diseases in whichorgans and cells undergo damage mediated by tissue binding auto antibodies and immune complexes 1 SLE affects 2 to 8 persons per 100,000 in United States. Most cases occur in women of childbearing years. African, Asian and Native Americans are three times more likely to develop than whites Etiology is unknown.Mostprobable causes are Genetic influence, Hormonal imbalance, Environmental factors and certain medications. The diagnosing signs and symptoms aremalarrash,discoid rash,serositis, oral ulcers,arthritis, photo sensitivity blood problems (leukopenia),renal Failure,ANA (+),immunologic Problems,neurologic Problems(cerebritis) 2.Under clinical manifestationsmusculoskeletal manifestations are-Polyarthralgia with morning stiffness,Arthritis, Swan neck fingers,Ulnar deviation,Subluxation with hyper laxity ofjoints Cardiopulmonary manifestationsare Tachypnea, Pleurisy, Dysrhythmias, Accelerated CAD, Pericarditis Renalmanifestations are Lupus nephritis ranging from mild proteinuria to glomerulonephritis.Primary goal in treatment is slowing the progression Nerological manifestationsare generalized/focal seizures, peripheral neuropathy, cognitive dysfunction, disorientation, memory deficits and psychiatric symptoms Hematologic manifestations are formation of antibodies against blood cells, anemia, leucopenia, thrombocytopenia, coagulopathy. Incidence of systemic manifestations of SLE are Systemic fatigue, malaise, fever, anorexia, weight loss-95%,Musculoskeleton- 95%,Cutaneous-60%,Haematological- 85%,Neurological-60%,Cardiopulmonary- 60%,Renal-30 to 50%,Gastrointestinal- 40%,Thrombosis-15%,Ocular-15% 3 Case report - A 26 year old female patient Case Report International Ayurvedic Medical Journal ISSN:2320 5091 ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterizedby the production of auto antibodies resulting from the dysfunction of T cells, B cells and dendritic cells. Ninetypercents of patients are women of child bearing years. People of both sexes, all ages and all ethnic groups are susceptible. Here we are reporting a case of SLE of a 26 year old female patient. The possible understanding of the case in terms of Ayurveda and a therapeutic protocol with promising result has been discussed. Keywords: SLE, autoantibodies, dendritic cells How to cite this URL