Toxicity study of unmadgajakesari rasa [ugk] and its antipsychotic activity in animal models
Journal name: International Ayurvedic Medical Journal
Original article title: Toxicity study of unmadgajakesari rasa [ugk] and its antipsychotic activity in animal models
The International Ayurvedic Medical Journal (IAMJ) is a peer-reviewed scientific publication dedicated to Ayurveda. It aims to integrate Ayurvedic concepts with modern scientific understanding, offering a comprehensive source of validated knowledge for both the modern Ayurvedic community and the broader medical fraternity.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Jyoti Singh
Asmita Wele
International Ayurvedic Medical Journal:
(Publishing full-length original papers and reviews on ayurveda)
Full text available for: Toxicity study of unmadgajakesari rasa [ugk] and its antipsychotic activity in animal models
Year: 2016
Copyright (license): CC BY-NC-ND 3.0
Download the PDF file of the original publication
Summary of article contents:
Schizophrenia is a severe, chronic, and generally disabling brain and behavior disorder that disrupt normal thoughts, speech, and behavior Unmadgajakesari Rasa [UGK], a potent herbomineral formulation claimed to be useful in Schizophrenia in traditional medicine. Due to lack of scientific evidences of its use in Schizophrenia lead to objective of the present work. After doing the acute toxicity study of UGK, it was evaluated for its antipsychotic activity in 5 HTP induced head twitches model and extra pyramidal adverse effect in catalepsy model in albino mice. For each study animals were divided into 4 groups, each group comprising of 6 animals. Group I- Vehicle Control group ( ghrita ), Group II- Standard Drug Group. In test group UGK was administered in the doses of 7.8 mg and 15.6 mg orally.Acute toxicity study revealed that UGK was nontoxic at 2000 mg/kg dose. It shows statistically significant [p<0.001] antipsychotic activity in 5 HTP induced head twitches model. It does not produce catalepsy [p< 0.001] which is a known adverse effect of antipsychotic drug. Keywords: Schizophrenia, Unmadgajakesari rasa , acute toxicity study,
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘Toxicity study of unmadgajakesari rasa [ugk] and its antipsychotic activity in animal models’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
Samskara, Cow urine, Central nervous system, Statistically Significant, Animal model, Acute toxicity, Antipsychotic activity, Herbomineral formulation, Toxicity study, Ayurveda practice, Neuroprotective effect, Psychological disorder, Administration Route, Dose level.