Toxicological evaluation of rasa-sindoor in albino rats
Journal name: International Ayurvedic Medical Journal
Original article title: Toxicological evaluation of rasa-sindoor in albino rats
The International Ayurvedic Medical Journal (IAMJ) is a peer-reviewed scientific publication dedicated to Ayurveda. It aims to integrate Ayurvedic concepts with modern scientific understanding, offering a comprehensive source of validated knowledge for both the modern Ayurvedic community and the broader medical fraternity.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Kanojia Anita Sharma Anita Urimindi Venketeswarlu Gotecha Vinod Kumar
International Ayurvedic Medical Journal:
(Publishing full-length original papers and reviews on ayurveda)
Full text available for: Toxicological evaluation of rasa-sindoor in albino rats
Year: 2013
Copyright (license): CC BY-NC-ND 3.0
Download the PDF file of the original publication
Summary of article contents:
Ayurvedic formulations containing heavy metals are used therapeutically since ages. However the safety of these formulations is questioned on time to time by modern counterparts as metals in their elemental form are very toxic. The present study was carried out with an aim to screen out toxicity (if any) of Rasa-Sindoor, an Ayurvedic formulation on kidney and its functioning in albino rats (Wistar strain). Total 30 albino rats were taken for the study and they were divided into 5 groups, 1 st group was control group while other 4 groups were administered two samples of Rasasindoor i) Hingulottha Parada Rasasindoor and ii) Shodhita Parada Rasasindoor in two different doses (50 mg/kg and 100 mg/kg respectively) orally for 28 days consecutively. Effect of test drugs on kidney was evaluated on biochemistry (Renal function test) and postmortem histopathological parameters. This study revealed normal behaviour, no mortality, no significant changes in renal functions test and no drug related morphological changes in histopathological examination. It was found that in 28 days of study, in comparison to control group Rasasindoor treated groups did not have any adverse effect on kidney. Keywords: Rasasindoor, Hingulottha Parada, Heavy metals, Toxicity Kanojia Anita et
Other Science Concepts:
Discover the significance of concepts within the article: ‘Toxicological evaluation of rasa-sindoor in albino rats’. Further sources in the context of Science might help you critically compare this page with similair documents:
Adverse effect, Significant change, World Health Organisation, Safety profile, Immunomodulator, Toxicological evaluation, Shodhita Parada, Institutional Animal Ethical committee, Hingulottha Parada, Heavy metal, Therapeutic dose, Pharmacovigilance, Renal function test, Ayurvedic medicinal system, Shodhana processes, Morphological change, Albino rat, Pharmaceutical practice.