Formulation and Evaluation of Herbal Emulgel Containing Syzigium Cumini Extract
Journal name: Ayushdhara
Original article title: Formulation and Evaluation of Herbal Emulgel Containing Syzigium Cumini Extract
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Sheetal S. Samant
Assistant Professor, Department of Pharmacognosy, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Vijay A. Jagtap
Principal, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Prajakt Kalangutkar
Student, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Akshaya Gadekar
Student, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Riddhi Rane
Student, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Raghunath Morye
Student, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Samidha Desai
Student, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Formulation and Evaluation of Herbal Emulgel Containing Syzigium Cumini Extract
Year: 2023 | Doi: 10.47070/ayushdhara.v10i6.1424
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
The use of herbal therapies is gaining popularity among patients and healthcare providers, particularly for the treatment of various skin diseases. Traditional Indian medicines, rooted in Ayurveda, are known to address conditions such as inflammation, skin infections, and ulcers. Among the numerous herbal remedies, the bark of Syzygium cumini, commonly known as Jamun, has been utilized for its anti-inflammatory properties. This study aims to formulate a herbal emulgel incorporating the extract of Syzygium cumini and evaluate its potential for treating skin inflammation.
Phytochemical and Anti-Inflammatory Properties
The extract of Syzygium cumini was obtained using a hydro-alcoholic solvent and underwent thorough phytochemical screening to identify the presence of various bioactive compounds, including alkaloids, flavonoids, carbohydrates, and tannins. The in-vitro anti-inflammatory activity was assessed using the Human Red Blood Cell (HRBC) membrane stabilization method. This technique demonstrated the extract's capability to stabilize the membrane, indicating its anti-inflammatory efficacy. The results indicated significant membrane protection at various concentrations, showcasing the extract's potential therapeutic benefits against inflammation.
Emulgel Formulation and Evaluation
A total of four emulgel formulations were created, each varying in gelling agents and their concentrations. Several physical parameters were assessed including pH, viscosity, spreadability, and overall consistency. The formulation F2 exhibited the best results in terms of stability and physical characteristics. It was stable throughout the conducted stability studies, which involved storage under both accelerated and room temperature conditions. These assessments confirmed that F2 could effectively function as a topical formulation for skin inflammation treatment.
Conclusion
The study concludes that the herbal emulgel formulated with Syzygium cumini extract offers a promising natural remedy for skin inflammation, demonstrating both stability and significant anti-inflammatory potential. Given the growing demand for safer alternative therapies, this herbal emulgel may cater to patients seeking effective treatments with fewer side effects compared to conventional pharmaceuticals. Continued exploration in this area may unveil further applications of traditional herbs in modern therapeutic formulations.
FAQ section (important questions/answers):
What is the main purpose of the herbal emulgel study?
The study aimed to formulate an emulgel containing Syzygium cumini extract, primarily to evaluate its effectiveness in treating inflammation and to explore its potential use in topical applications.
How was the anti-inflammatory activity of Syzygium cumini assessed?
The anti-inflammatory activity was evaluated using the Human Red Blood Cell (HRBC) membrane stabilization method, measuring the absorbance to determine the extract’s effectiveness in preventing cell lysis.
Which formulation of emulgel showed the best stability and performance?
Formulation F2 demonstrated the best stability and physical characteristics, including good consistency and anti-inflammatory activity, making it suitable for topical treatment of skin inflammation.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Formulation and Evaluation of Herbal Emulgel Containing Syzigium Cumini Extract”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Syzygium cumini:
Syzygium cumini, commonly known as Jamun or Java Plum, is an evergreen tropical tree native to India and other regions. The bark of this tree has been traditionally used in Indian medicine to treat inflammation and other conditions.
2) Medicine:
Medicine refers to substances or preparations used in treating diseases or conditions in humans. Herbal medicine, such as those prepared from Syzygium cumini, offers an alternative to synthetic drugs, often valued for fewer side effects and better compatibility with the human body
3) Drug:
A drug is a substance used to diagnose, cure, treat, or prevent disease. For instance, an emulgel containing Syzygium cumini extract can act as a topical drug to combat inflammation, leveraging the therapeutic benefits of the plant
4) Powder:
Powder form is often the first step in preparing herbal medicines. Syzygium cumini bark is dried and ground into a coarse powder, which is then used for extraction processes to obtain the active phytochemicals for medicinal use
5) Phytochemical:
Phytochemicals are bioactive compounds present in plants. In Syzygium cumini, phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, and other beneficial components that contribute to its anti-inflammatory properties
6) Inflammation:
Inflammation is the body's response to injury or infection, often causing redness, swelling, and pain. Syzygium cumini has been traditionally used to treat inflammation, and its efficacy was studied through formulations like emulgels for topical application
7) Blood:
Blood is crucial in various biomedical tests, such as the Human Red Blood Cell (HRBC) membrane stabilization method used to evaluate the anti-inflammatory activity of Syzygium cumini extract
8) Flavonoid:
Flavonoids are a class of plant secondary metabolites known for their anti-inflammatory and antioxidant properties. Syzygium cumini extract includes flavonoids, contributing to its medicinal benefits
9) Sheetal:
Sheetal S. Samant is one of the authors of the research on the formulation and evaluation of herbal emulgel containing Syzygium cumini extract. She is an Assistant Professor in the Department of Pharmacognosy
10) Disease:
Disease refers to any condition that impairs normal functioning in the human body. Traditional herbal medicines, including those made from Syzygium cumini, are used to treat a variety of skin diseases and inflammatory conditions
11) Indian:
Indian refers to anything related to India. The Indian system of medicine, particularly Ayurveda, often utilizes plants like Syzygium cumini for their therapeutic properties.
12) India:
India is the country where Syzygium cumini is commonly found and used in traditional medicine. The research conducted on this plant contributes to the understanding and development of Indian herbal remedies
13) Shri (Sri, Sr):
Shri Pancham Khemraj Mahavidyalaya is the institution that authenticated the Syzygium cumini bark used in this research. It is located in Sawantwadi, Maharashtra, India
14) Curcuma longa:
Curcuma longa, also known as turmeric, is another medicinal plant traditionally used to treat inflammation. Like Syzygium cumini, it is valued for its anti-inflammatory properties
15) Mustard oil:
Mustard oil is one of the components used in the formulation of the herbal emulgel containing Syzygium cumini extract. It is used for its beneficial skin properties and helps in the emulsification process
16) Human body:
The human body is the ultimate recipient of medicinal treatments. Natural remedies like Syzygium cumini are often preferred for their compatibility and fewer side effects compared to synthetic drugs
17) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India where Yashwantrao Bhonsale College of Pharmacy and Shri Pancham Khemraj Mahavidyalaya are located, both of which contributed to the research on Syzygium cumini
18) Discussion:
Discussion in scientific contexts entails analysis and interpretation of results. This research’s discussion focuses on the efficacy and stability of the herbal emulgel formulations containing Syzygium cumini extract
19) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that uses herbal formulations to treat various ailments. Syzygium cumini is one such plant used in Ayurveda for its anti-inflammatory properties
20) Mustard:
Mustard, although generally referred to as a plant and its seeds, here refers to Mustard oil, which is used in the preparation of the herbal emulgel. It aids in the emulsification and provides additional skin benefits
21) Leprosy:
Leprosy is a chronic infectious disease. Traditional Indian medicine, including the use of Syzygium cumini, has been employed to treat a variety of diseases, though the focus of this research is on inflammation
22) Riddhi (Rddhi):
Riddhi Rane is one of the students involved in the research on formulating and evaluating a herbal emulgel containing Syzygium cumini extract
23) Family:
Family in botanical terms refers to the classification of plants. Syzygium cumini belongs to the family Myrtaceae, which includes several other plants with medicinal properties
24) Nature:
Nature encompasses plants, animals, and other organisms in the ecosystem. Natural remedies, such as those derived from Syzygium cumini, are essential in medicine for their therapeutic benefits
25) Ayus (Ayush):
Ayush is an acronym for Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy, which are traditional medicine systems in India. The journal AYUSHDHARA publishes research in these fields, including studies on Syzygium cumini
26) Jamun:
Jamun is a common name for Syzygium cumini. It is widely recognized in India and other tropical regions for its medicinal properties, particularly in treating inflammation
27) Ulcer:
Ulcers are open sores that can occur on the skin or mucous membranes. Traditional Indian medicine, like that using Syzygium cumini, has been employed to treat various skin conditions, though this research focuses on inflammation
28) Java:
Java refers to the common name Java Plum for Syzygium cumini. It highlights the plant's recognition and use beyond India, extending to Indonesia and other regions
29) Tree:
Tree refers to Syzygium cumini, which is an evergreen tropical tree used in traditional medicine to treat inflammation and other conditions. It belongs to the Myrtaceae family
Other Science Concepts:
Discover the significance of concepts within the article: ‘Formulation and Evaluation of Herbal Emulgel Containing Syzigium Cumini Extract’. Further sources in the context of Science might help you critically compare this page with similair documents:
Syzygium cumini, Physical appearance, Indian system of medicine, Anti-inflammatory activity, Traditional healer, Phytochemical evaluation, Soxhlet extraction, Stability Studies, Viscosity measurement, Spreadability, Pharmaceutical formulation, HRBC membrane stabilization method, Gelling agent, Topical drug delivery system, Herbal emulgel, Extraction of plant material, Anti-inflammatory plant, Natural bioactive components.