Efficacy of Ayurvedic Formulations in Dyslipidemia (Medo Dusti)
Journal name: Ayushdhara
Original article title: Efficacy of Ayurvedic Formulations in Dyslipidemia (Medo Dusti)
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Pramod Kapoor
PG Scholar, Dept. of Kayachikitsa, Ch. Brahm Prakash Ayurved charak Sansthan, Khera dabar, New Delhi, India
Shushma Upadhyay
PG Scholar, Dept. of Kayachikitsa, Ch. Brahm Prakash Ayurved charak Sansthan, Khera dabar, New Delhi, India
Shivani Shekhawat
PG Scholar, Dept. of Kayachikitsa, Ch. Brahm Prakash Ayurved charak Sansthan, Khera dabar, New Delhi, India
Bhawana Aggarwal
PG Scholar, Dept. of Kayachikitsa, Ch. Brahm Prakash Ayurved charak Sansthan, Khera dabar, New Delhi, India
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Efficacy of Ayurvedic Formulations in Dyslipidemia (Medo Dusti)
Year: 2023 | Doi: 10.47070/ayushdhara.v10iSuppl4.1343
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Obesity and dyslipidemia are significant health concerns globally, with overweight conditions linked to an increased risk of various diseases, including diabetes and cardiovascular issues. Dyslipidemia, characterized by elevated levels of total cholesterol, low-density lipoprotein (LDL), and triglycerides in the blood, is related to metabolic disorders and is referred to as "Medoroga" in Ayurvedic texts. This case study presents a patient diagnosed with dyslipidemia, showing an imbalance in lifestyle and mental stress leading to a weight increase from 65 kg to 71 kg over three months. Conventional management for such cases often underscores the importance of lifestyle modification and pharmacological interventions.
Efficacy of Ayurvedic Formulations in Treating Dyslipidemia
The patient's management involved a combination of Ayurvedic formulations: Arogyavardhini vati, Navak guggul, and Darvyadi Kwath, along with a structured diet plan. After a 34-day intervention period, notable improvements were recorded in lipid profiles and weight. Total cholesterol decreased from 162 mg/dl to 136 mg/dl, and triglycerides reduced significantly from 217.7 mg/dl to 90 mg/dl, while the patient’s weight also dropped from 71 kg to 68 kg. This improvement can be attributed to the hypolipidemic effects of the formulated medications, which target the metabolic dysfunction and promote the normalization of lipid levels.
Role of Specific Ingredients in Ayurvedic Formulations
The components of Arogyavardhini vati, including Picrorrhiza kurroa and Guggulu, are known for their lipid-lowering properties. These ingredients work synergistically to inhibit enzymes involved in cholesterol production and improve lipid metabolism. Similarly, Navak guggul contains herbs that contribute to the balancing of Kapha and Meda doshas, which are critical in managing conditions like obesity and dyslipidemia. Darvyadi Kwath's formulation, classified under Lekhaniya mahakashaya, incorporates ingredients that possess properties to clear excess fat and toxins from the body. Each component aids in restoring metabolic balance, underscoring the therapeutic potential of Ayurvedic formulations in managing dyslipidemia.
Conclusion
The efficacy of Ayurvedic formulations in managing dyslipidemia reflects a holistic approach that combines diet, lifestyle modification, and targeted herbal therapies. This case study illustrates the significant benefits of Ayurvedic treatment in reducing lipid levels and associated weight in an overweight patient. Results from Ayurvedic interventions underscore the multifaceted pharmacological activities of the ingredients used, highlighting their role in promoting metabolic health and addressing complications arising from Meda dusti. Further research may solidify these findings, offering a complementary strategy alongside conventional methods in treating dyslipidemia and obesity.
FAQ section (important questions/answers):
What is dyslipidemia and how is it related to obesity?
Dyslipidemia is characterized by abnormal lipid levels in the blood, including high cholesterol and triglycerides. It is often associated with obesity, as increased body weight leads to metabolic disorders, raising the risk of cardiovascular diseases.
What Ayurvedic formulations were used to treat the patient?
The patient was treated with Arogyavardhini vati, Navak guggul, and Darvyadi Kwath. This combination aimed to reduce lipid levels and body weight, addressing the underlying issues of Meda dusti effectively over a 34-day period.
What were the results of the Ayurvedic treatment after 34 days?
After 34 days of treatment, the patient's triglycerides decreased from 217.7 mg/dl to 90 mg/dl, while total cholesterol reduced from 162 mg/dl to 136 mg/dl, and weight decreased from 71 kg to 68 kg.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of Ayurvedic Formulations in Dyslipidemia (Medo Dusti)”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Medas (Meda, Medash):
In the context of Ayurveda, Meda refers to fat tissue. It is considered one of the seven Dhatus (tissues) and is involved in maintaining the structure and lubrication of the body. Excessive Meda is associated with disorders like obesity and Medoroga [see source text or glossary: Meda].
2) Disease:
In Ayurveda, a disease is an imbalance in the Doshas (Vata, Pitta, Kapha) that disrupts the harmony among the body's Dhatus. Dyslipidemia is an example of a disease caused by an imbalance in Meda, resulting in conditions like obesity and cardiovascular issues [see source text or glossary: Disease].
3) Kapha:
Kapha is one of the three Doshas in Ayurveda, associated with water and earth elements. It provides structure and stability to the body. Imbalance in Kapha can lead to conditions like Meda Dusti (fat disorder) and obesity [see source text or glossary: Kapha].
4) Dhatu:
Dhatus are the seven fundamental tissues in Ayurveda, including Meda (fat tissue). Each Dhatu has specific functions and imbalances can lead to diseases. For instance, Meda Dhatu imbalances can result in obesity and related ailments [see source text or glossary: Dhatu].
5) Vati:
Vati refers to a tablet or pill in Ayurvedic medicine. Arogyavardhini Vati, for example, is used to manage dyslipidemia by balancing Meda and Kapha Doshas, and includes ingredients like Picrorrhiza kurroa and Commiphora mukul [see source text or glossary: Vati].
6) Guggulu:
Guggulu is an Ayurvedic term for the resin derived from the Commiphora mukul tree. It is often used in formulations like Navak Guggulu for its lipid-lowering properties. Guggulu helps reduce Meda Dhatu and balances Kapha Dosha [see source text or glossary: Guggulu].
7) Rasa (Rasha):
In Ayurveda, Rasa refers to taste and is one of the primary qualities of a substance. Different Rasas (tastes) have various effects on the Doshas. For example, Katu Rasa (pungent taste) is used to reduce Kapha and Meda [see source text or glossary: Rasa].
8) Drug:
In the context of the article, drugs refer to Ayurvedic formulations like Arogyavardhini Vati and Navak Guggulu, used to treat dyslipidemia and obesity. These drugs help balance Doshas and improve lipid profiles [see source text or glossary: Drug].
9) Medadhatu (Meda-dhatu):
Medadhatu is the fat tissue in Ayurveda. It provides lubrication and insulation, but its imbalance can lead to obesity and dyslipidemia. Ayurvedic treatments focus on reducing excess Meda Dhatu [see source text or glossary: Medadhatu].
10) Ruksha (Ruksa):
Ruksha is a quality or Guna in Ayurveda, meaning dry. Substances with Ruksha Guna are used to balance Kapha and Meda Dhatu by reducing excess moisture and fat in the body. [see source text or glossary: Ruksha].
11) Blood:
Blood, or Rakta in Ayurveda, is one of the Dhatus essential for life. Imbalances can indicate various health issues. For instance, lipid profiles in blood tests can indicate dyslipidemia, a Meda Dhatu disorder [see source text or glossary: Blood].
12) Katu:
Katu refers to the pungent taste in Ayurveda. It has a dry and hot quality, useful in reducing Kapha and Meda Dhatu. Ingredients like Sunthi (Zingiber officinale) possess Katu Rasa and are used in treatments for obesity [see source text or glossary: Katu].
13) Sthaulya:
Sthaulya, equivalent to obesity in Ayurveda, is considered a disorder of Meda Dhatu. It is treated using Ayurvedic formulations that balance Kapha and reduce excess Meda. Obesity is one of the eight diseases mentioned by Acharya Charak [see source text or glossary: Sthaulya].
14) Darvyadi (Darvi-adi):
Darvyadi refers to a group of Ayurvedic herbs including Daruharidra (Berberis aristata), used for treating Medoroga (dyslipidemia). Darvyadi Kwath is a decoction made from these herbs with properties to reduce Kapha and Meda [see source text or glossary: Darvyadi].
15) Laghu:
Laghu means light, and is a Guna (quality) in Ayurveda. Substances with Laghu Guna are easy to digest and useful in reducing Kapha and Meda Dhatu. Medicines with Laghu properties help manage obesity and dyslipidemia [see source text or glossary: Laghu].
16) Diet:
In Ayurveda, diet (Pathya) plays a crucial role in managing diseases. A balanced diet helps in correcting Meda Dusti and imbalances in Kapha Dosha. The article emphasizes the importance of a planned diet for treating dyslipidemia [see source text or glossary: Diet].
17) Commiphora mukul:
Commiphora mukul, known as Guggulu, is a resin used in Ayurvedic medicine for its anti-inflammatory and lipid-lowering properties. It is a key ingredient in formulations like Navak Guggulu for treating Medoroga [see source text or glossary: Commiphora mukul].
18) Daruharidra (Daru-haridra):
Daruharidra, or Berberis aristata, is a medicinal herb used in Ayurveda. It has anti-inflammatory and lipid-lowering properties and is a critical component of Darvyadi Kwath, employed in treating dyslipidemia [see source text or glossary: Daruharidra].
19) Lekhaniya:
Lekhaniya refers to a group of Ayurvedic herbs known for their scraping properties, useful in reducing excess fat. These herbs are used in formulations like Darvyadi Kwath to correct Meda Dusti and balance Kapha [see source text or glossary: Lekhaniya].
20) Medicine:
In the context of the article, medicine refers to Ayurvedic formulations like Arogyavardhini Vati and Navak Guggulu, used for treating Medoroga by balancing Meda Dhatu and Kapha Dosha [see source text or glossary: Medicine].
21) Pathya:
Pathya in Ayurveda refers to a prescribed diet and lifestyle suitable for the treatment of specific diseases. For Medoroga, a Pathya diet includes warm water, barley, and green vegetables to balance Meda Dhatu and Kapha Dosha [see source text or glossary: Pathya].
22) Dosha (Dosa):
Doshas are the fundamental bodily bio-elements in Ayurveda, namely Vata, Pitta, and Kapha. Imbalances in Doshas lead to diseases. Dyslipidemia is linked to an imbalance in Kapha Dosha and Meda Dhatu [see source text or glossary: Dosha].
23) Ushna (Usna):
Ushna means hot and is a characteristic attributed to some substances in Ayurveda. Herbal formulations with Ushna qualities are used to reduce Kapha and balance Meda Dhatu in conditions like obesity [see source text or glossary: Ushna].
24) Guna:
Gunas are qualities of substances in Ayurveda, such as Laghu (light) and Ruksha (dry). These qualities help in balancing Doshas and Dhatus. For dyslipidemia, ingredients with Ruksha and Laghu Gunas are used to manage Meda Dhatu [see source text or glossary: Guna].
25) Emblica officinalis:
Emblica officinalis, or Amla, is a common Ayurvedic herb with hypolipidemic properties. It is a key ingredient in formulations like Arogyavardhini Vati, used to treat Medoroga by balancing Meda Dhatu and Kapha Dosha [see source text or glossary: Emblica officinalis].
26) Terminalia chebula:
Terminalia chebula, known as Haritaki, is an Ayurvedic herb used to balance Meda Dhatu and Kapha Dosha. It is a component of formulations like Navak Guggulu for treating dyslipidemia and obesity [see source text or glossary: Terminalia chebula].
27) Berberis aristata:
Berberis aristata, or Daruharidra, is a medicinal herb with lipid-lowering and anti-inflammatory properties. It is a key ingredient in Darvyadi Kwath, used in treating Medoroga by reducing Meda and balancing Kapha [see source text or glossary: Berberis aristata].
28) New Delhi:
New Delhi is the location where the case study in the article takes place. The patient visited the Ch. Brahm Prakash Ayurved Charak Sansthan in New Delhi for treatment of dyslipidemia and obesity [see source text or glossary: New Delhi].
29) Katurasa (Katu-rasa):
Katu-rasa refers to the pungent taste in Ayurveda, which has dry and hot qualities. Substances with Katu-rasa, like Sunthi (Zingiber officinale), are used to manage conditions related to Kapha and Meda Dhatu imbalances [see source text or glossary: Katu-rasa].
30) Vitiation (Vitiated):
Vitiation in Ayurveda refers to the imbalance or disturbance of Doshas or Dhatus. Dyslipidemia is an example of Medo Dhatu vitiation, where there is an excess of lipids in the body [see source text or glossary: Vitiation].
31) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India that emphasizes balance among the body's Doshas, Dhatus, and Malas. It employs herbs, diet, and lifestyle changes to treat diseases, like Medoroga or dyslipidemia [see source text or glossary: Ayurveda].
32) Medoroga (Medas-roga):
Medoroga is an Ayurvedic term for diseases of the fat tissue, primarily dyslipidemia and obesity. It involves an imbalance in Meda Dhatu and Kapha Dosha, leading to symptoms like weight gain and elevated lipid levels [see source text or glossary: Medoroga].
33) Vidanga (Vidamga):
Vidanga, or Embelia ribes, is an Ayurvedic herb used to treat Medoroga. It purifies blood and reduces Meda Dhatu by enhancing Raktagni. It is a component of Navak Guggulu, used for dyslipidemia and obesity [see source text or glossary: Vidanga].
34) Vipaka:
Vipaka is the post-digestive effect of a substance in Ayurveda, influencing Doshas and Dhatus. Katu vipaka, for instance, aids in reducing Kapha and Meda Dhatu, helping in the treatment of dyslipidemia [see source text or glossary: Vipaka].
35) Shunthi (Sunthi, Sumthi, Shumthi):
Sunthi, or Zingiber officinale, is an Ayurvedic herb with Katu Rasa (pungent taste) and is used to reduce Kapha and Meda Dhatu. It is an ingredient in Navak Guggulu, used for treating dyslipidemia and obesity [see source text or glossary: Sunthi].
36) Musta (Mushta):
Musta, or Cyperus rotundus, is an Ayurvedic herb used in the treatment of Medoroga. It acts as an astringent, appetizer, and digestive agent, and is a component of Navak Guggulu, aiding in reducing Meda Dhatu [see source text or glossary: Musta].
37) Tikta:
Tikta refers to the bitter taste in Ayurveda. Substances with Tikta Rasa are often used to balance Kapha Dosha and reduce Meda Dhatu. They are part of formulations like Darvyadi Kwath for treating dyslipidemia [see source text or glossary: Tikta].
38) Virya:
Virya refers to the potency or energetic effect of a substance in Ayurveda. Ushna Virya (hot potency) substances are used to reduce Kapha and Meda Dhatu, helping manage conditions like obesity and dyslipidemia [see source text or glossary: Virya].
39) Delhi:
Delhi is the region where the case study mentioned in the article takes place. The patient visited the Ayurvedic clinic located in New Delhi for treatment of obesity and dyslipidemia [see source text or glossary: Delhi].
40) Agni:
Agni in Ayurveda refers to the digestive fire, responsible for metabolism. Imbalance in Agni can lead to disorders like Medoroga. Treatments aim to balance Agni to ensure proper digestion and metabolism [see source text or glossary: Agni].
41) Gana:
Gana refers to a group of herbs in Ayurveda that share similar properties. Lekhaniya Gana, for example, is a group of herbs used to reduce Meda Dhatu and treat dyslipidemia [see source text or glossary: Gana].
42) Food:
In Ayurveda, food (Aahar) plays a critical role in maintaining health. A Pathya diet helps in balancing Doshas and Dhatus. For dyslipidemia, a diet that reduces Meda Dhatu and Kapha Dosha is recommended [see source text or glossary: Food].
43) Salt (Salty):
Salt, or Lavana, is generally restricted in Ayurvedic treatments for obesity and dyslipidemia, as it can aggravate Kapha and Meda Dhatu. A low-salt diet helps in managing these conditions [see source text or glossary: Salt].
44) Zingiber officinale:
Zingiber officinale, known as Sunthi or ginger, is an Ayurvedic herb with Katu Rasa (pungent taste). It helps in reducing Kapha and Meda Dhatu, and is used in formulations like Navak Guggulu for treating dyslipidemia [see source text or glossary: Zingiber officinale].
45) Cyperus rotundus:
Cyperus rotundus, known as Musta, is an Ayurvedic herb used for its astringent and digestive properties. It reduces Meda Dhatu and is a component of Navak Guggulu for treating Medoroga [see source text or glossary: Cyperus rotundus].
46) Piper longum:
Piper longum, or Pippali, is an Ayurvedic herb with Katu Rasa (pungent taste). It helps in reducing Kapha and Meda Dhatu, and is a key ingredient in formulations for treating dyslipidemia and obesity [see source text or glossary: Piper longum].
47) Terminalia bellirica:
Terminalia bellirica, known as Bibhitaki, is an Ayurvedic herb used to balance Meda Dhatu. It is a component of formulations like Navak Guggulu, used for treating dyslipidemia and reducing excess fat [see source text or glossary: Terminalia bellirica].
48) Plumbago zeylanica:
Plumbago zeylanica, known as Chitraka, is an Ayurvedic herb with digestive and lipid-lowering properties. It helps in managing Kapha and Meda Dhatu, and is a component of Navak Guggulu [see source text or glossary: Plumbago zeylanica].
49) Pharmacological:
Pharmacological refers to the properties and effects of drugs. Ayurvedic formulations discussed in the article have multiple pharmacological activities, like hypolipidemic and anti-obesity effects, to treat Medoroga [see source text or glossary: Pharmacological].
50) Embelia ribes:
Embelia ribes, known as Vidanga, is an Ayurvedic herb used in treating Medoroga. It helps purify blood and reduce Meda Dhatu by optimizing Raktagni and balancing Kapha [see source text or glossary: Embelia ribes].
51) Mahakashaya (Mahakasaya, Maha-kashaya):
Mahakashaya refers to a category of Ayurvedic formulations containing specific groups of herbs. Lekhaniya Mahakashaya, for example, includes herbs that help reduce Meda Dhatu and treat dyslipidemia [see source text or glossary: Mahakashaya].
52) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha Dosha is one of the three Doshas in Ayurveda, associated with stability and structure. Imbalance in Kapha leads to disorders like Meda Dusti and obesity. Treatments aim to balance Kapha and Meda Dhatu [see source text or glossary: Kapha-dosha].
53) Pomegranate:
Pomegranate is recommended in the diet plan for treating Medoroga, as it is considered beneficial for reducing Meda Dhatu and balancing Kapha Dosha. It is low in calories and rich in antioxidants [see source text or glossary: Pomegranate].
54) Rasadhatu (Rasa-dhatu):
Rasa Dhatu is the first and most important tissue in Ayurveda, responsible for nourishing all other tissues, including Meda Dhatu. Its imbalance can lead to various diseases including dyslipidemia [see source text or glossary: Rasa-dhatu].
55) Kaphavata (Kapha-vata):
Kapha-Vata refers to the combined effect of Kapha and Vata Doshas. Imbalance in both can lead to complex conditions like Meda Dusti. Treatment aims to balance these Doshas to ensure proper function [see source text or glossary: Kapha-vata].
56) Discussion:
The discussion section of the article elaborates on the effectiveness of Ayurvedic formulations in treating dyslipidemia. It emphasizes the properties of herbs and their roles in balancing Meda Dhatu and Kapha [see source text or glossary: Discussion].
57) Vishaghna (Visaghna, Visha-ghna):
Vishaghna refers to the properties of a substance that neutralizes toxins. Ayurvedic formulations with Vishaghna properties help in reducing Amavisha and managing Meda Dhatu disorders like dyslipidemia [see source text or glossary: Vishaghna].
58) Haritaki:
Haritaki, or Terminalia chebula, is an Ayurvedic herb used to balance Meda Dhatu. It is a key component in formulations like Navak Guggulu for treating dyslipidemia and obesity by reducing Kapha [see source text or glossary: Haritaki].
59) Triphala (Tri-phala):
Triphala is a combination of three fruits: Amalaki, Bibhitaki, and Haritaki. It is used in Ayurveda to balance Meda Dhatu and Kapha Dosha. It helps manage dyslipidemia and improves overall health [see source text or glossary: Triphala].
60) Pariksha (Pariksa):
Pariksha refers to the examination or diagnosis process in Ayurveda. It involves assessing Doshas, Dhatus, and other factors to diagnose conditions like Medoroga and formulate treatment plans [see source text or glossary: Pariksha].
61) Raktagni (Rakta-agni):
Raktagni refers to the metabolic fire specific to the blood tissue in Ayurveda. Proper Raktagni ensures balanced Meda Dhatu and prevents lipid disorders like dyslipidemia [see source text or glossary: Raktagni].
[Note: The above list is limited to 75. Total glossary definitions available: 104]
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