Management of Primary Open Angle Glaucoma: Ayurvedic vs. Modern

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Journal name: Ayushdhara
Original article title: Management of Primary Open Angle Glaucoma (POAG): Ayurvedic and Modern Approaches
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Author(s):

Archana Bartwal
PG Scholar, Department of Shalakya, Patanjali Bhartiya Ayurvigyan evam Anusandhan Sansthan, Uttarakhand, India.
Dayashankar Singh
Professor, Department of Shalakya, Patanjali Bhartiya Ayurvigyan evam Anusandhan Sansthan, Uttarakhand, India.
Arun Kumar Pandey
Assistant Professor, Department of Shalakya, Patanjali Bhartiya Ayurvigyan evam Anusandhan Sansthan, Uttarakhand, India.


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: Management of Primary Open Angle Glaucoma (POAG): Ayurvedic and Modern Approaches

Year: 2023 | Doi: 10.47070/ayushdhara.v10iSuppl4.1278

Copyright (license): CC BY-NC-SA 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

Primary open-angle glaucoma (POAG) is a chronic eye condition often affecting adults, characterized by elevated intraocular pressure (IOP), optic nerve damage, and visual field loss. It is the second leading cause of irreversible blindness globally, with significant prevalence in India. This review compares the management of POAG from both Ayurvedic and modern medical perspectives, highlighting their similarities and differences, as well as the potential benefits of integrating these approaches for enhanced patient outcomes.

Modern Therapeutic Approaches

Modern medicine employs a range of therapeutic strategies to manage POAG, including medications, laser therapy, and surgical interventions aimed at lowering IOP to prevent visual damage. The most common medications include beta blockers, carbonic anhydrase inhibitors, and prostaglandin analogs, which are typically the first-line treatments for glaucoma. While these approaches are effective in controlling IOP, they do not necessarily prevent optic nerve damage that can progress even when IOP levels are normal. There is a growing recognition of the need for neuroprotective strategies alongside conventional treatments to address the condition more effectively. Recent advancements, such as Rho kinase inhibitors, offer promising avenues for enhancing outflow resistance in the eye.

Ayurvedic Perspectives

In Ayurveda, POAG is understood as a condition called Adhimantha, characterized by imbalances in the Pitta and Rakta doshas. Ayurvedic treatments aim to restore ocular health through a combination of therapies, herbal formulations, lifestyle modifications, and specific treatments like Kaphashodhana, which seeks to eliminate excess Kapha dosha. Various supportive herbal remedies, such as Triphala, are believed to possess antioxidant and anti-inflammatory properties that may benefit ocular health. Additionally, lifestyle modifications are emphasized to further improve overall eye health. The Ayurvedic approach focuses holistically on the individual, contrasting with the more symptom-targeted methods of conventional medicine.

Conclusion

Both Ayurvedic and modern approaches to managing POAG have their unique benefits and limitations, and integrating these two perspectives may offer a comprehensive strategy for treating this complex condition. While modern medicine predominantly addresses IOP reduction, Ayurveda provides a holistic understanding and treatment focused on restoring balance within the body. Collaboration between Ayurvedic practitioners and conventional healthcare providers could significantly enhance management outcomes for patients with POAG, promoting better vision preservation and overall ocular health. Further research and clinical trials will be essential in fully validating the effectiveness of integrated treatment strategies.

FAQ section (important questions/answers):

What is Primary Open-Angle Glaucoma (POAG)?

POAG is a chronic eye condition characterized by elevated intraocular pressure, optic nerve damage, and progressive visual field loss. It usually affects both eyes and can lead to irreversible blindness if not managed properly.

How do modern treatments for POAG work?

Modern treatments for POAG typically involve medications, laser therapy, or surgery to lower intraocular pressure. Various drugs are prescribed to improve ocular health, though optic nerve damage may still progress even with normal pressure levels.

What are Ayurvedic approaches to managing POAG?

Ayurvedic management of POAG focuses on balancing the doshas, using herbal formulations, and lifestyle modifications. Treatments include therapeutic fasting, medicated collyriums, and stress reduction techniques, aiming for holistic ocular health and disease prevention.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Management of Primary Open Angle Glaucoma: Ayurvedic vs. Modern”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Adhimantha:
Adhimantha is a term used in Ayurveda to describe a condition that resembles glaucoma. It specifically corresponds to angle-closure glaucoma, where pain is a significant symptom, unlike in primary open-angle glaucoma (POAG). The management involves treating various doshas and their disturbances in the body.

2) Disease:
Disease in the context of this text refers to primary open-angle glaucoma (POAG), a chronic condition characterized by elevated intraocular pressure, optic nerve damage, and visual field loss. The text discusses the Ayurvedic and modern approaches to managing this disease.

3) Blindness:
Blindness is a potential consequence of primary open-angle glaucoma (POAG), which can lead to irreversible loss of vision. The text highlights that glaucoma is a major cause of blindness globally and in India, emphasizing the need for effective management strategies.

4) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine from India that is used for managing various health conditions, including glaucoma. The text describes how Ayurvedic treatments involve therapies, herbal formulations, and lifestyle modifications aimed at improving ocular health and managing POAG.

5) Dosha (Dosa):
Dosha are fundamental bio-elements in Ayurveda, representing various bodily functions and constitutions. In the context of glaucoma, the text refers to doshas like Pitta and Rakta, which are implicated in the pathogenesis of Adhimantha, a condition analogous to glaucoma.

6) Rasayana (Rasa-ayana):
Rasayana in Ayurveda refers to rejuvenative therapies and substances that aim to promote health and longevity. Chakshushya Rasayana drugs in the text are noted for their specific benefits to ocular health, possessing antioxidant, neuroprotective, and immunity-enhancing properties.

7) India:
India is highlighted in the text as having a significant burden of glaucoma, with millions of individuals affected. The country's high prevalence of the disease underscores the relevance of integrating Ayurvedic and modern medical strategies for effective management.

8) Pain:
Pain is a notable symptom in angle-closure glaucoma (ACG) but not in primary open-angle glaucoma (POAG). The text points out that discomfort or a sensation of heaviness in the eye may occur in POAG when intraocular pressure is significantly elevated, but severe pain is not characteristic.

9) Drug:
Drug in the context of glaucoma refers to pharmaceutical interventions like beta blockers, cholinergic agents, carbonic anhydrase inhibitors, alpha-2 agonists, and prostaglandin analogs used in modern medicine to lower intraocular pressure and manage POAG.

10) Pitta:
Pitta is one of the doshas in Ayurveda, representing fire and water elements. It is involved in the pathogenesis of Adhimantha, where an imbalance can contribute to ocular issues like elevated intraocular pressure and optic nerve damage, analogous to primary open-angle glaucoma (POAG).

11) Discussion:
Discussion in the text refers to the comparative analysis of Ayurvedic and modern approaches to managing primary open-angle glaucoma (POAG). It emphasizes the need for a comprehensive treatment strategy that integrates both perspectives for improved patient outcomes.

12) Substance:
Substance in Ayurveda often refers to medicated preparations used for therapeutic purposes. The text mentions substances like herbal formulations and medicated substances applied externally or used in therapies like Anjana for ocular health in the management of POAG.

13) Avarodha:
Avarodha refers to the obstruction or blockage in Ayurvedic terms. In the context of glaucoma, Avarodha implicates blockages in the ocular channels, leading to increased resistance to aqueous humor outflow and elevated intraocular pressure, contributing to the disease's pathogenesis.

14) Drishti (Drsti, Drishtin, Drstin):
Drishti in Ayurveda refers to vision. The text indicates that visual disturbances and field defects, characteristic of glaucoma, are described in terms of Drishti—highlighting the impact of ocular conditions like POAG on vision and the importance of protective and rejuvenative therapies.

15) Anjana (Amjana):
Anjana in Ayurveda refers to the application of medicated collyrium on the eyes. The text notes its use as part of the therapeutic approach for managing Adhimantha and improving ocular health by delivering specific herbal compounds directly to the eyes.

16) Sharman (Sarma, Sharma, Sarman):
[see source text or glossary: Sharma]

17) Rakta:
Rakta represents blood in Ayurvedic terminology. The text aligns this with the role of blood in the pathogenesis of glaucoma, highlighting how factors like hypoperfusion, inflammation, or impaired local immunity contribute to disease progression.

18) Dhatu:
Dhatu in Ayurveda refers to the seven bodily tissues. Mention of Dhatu in the context of glaucoma involves discussions on the degeneration and remodelling of ocular tissues, which contribute to elevated intraocular pressure and optic nerve damage in conditions like POAG.

19) Kumar:
[see source text or glossary: Kumar]

20) Blood:
Blood plays a crucial role in both modern and Ayurvedic understandings of glaucoma. In Ayurveda, disruptions in blood flow and local immunity are key elements in the pathogenesis of Adhimantha. Modern approaches also recognize vascular factors in optic nerve health.

21) Saptamritalauha (Saptamrtalauha, Saptamrita-lauha):
Saptamrita-lauha is an Ayurvedic herbal formulation used for its therapeutic properties in ocular health. Cited in the text, it is believed to possess antioxidant and anti-inflammatory effects, thereby potentially reducing oxidative stress in managing POAG.

22) Vyadhikshamatva (Vyadhiksamatva):
Vyadhikshamatva denotes immunity in Ayurveda. Its deficiency, referred to as Vyadhikshamatva Hani, is implicated in the progression of diseases like glaucoma. Enhancing immunity, thus, forms a part of the comprehensive Ayurvedic approach to managing POAG.

23) Saptamritarasa (Saptamrtarasa, Saptamrita-rasa):
[see source text or glossary: Saptamritarasa]

24) Transformation (Transform, Transforming):
Transformation in the text refers to cellular changes within the ocular structures. Specifically, it involves the action of a novel anti-glaucomatous drug, Rho kinase inhibitor, which affects the cellular contraction and reduces resistance within the outflow pathways in glaucoma management.

25) Raktamokshana (Raktamoksana, Rakta-mokshana):
Raktamokshana refers to bloodletting, an Ayurvedic procedure aimed at cleansing the blood. It is used to manage Adhimantha by relieving internal blockages and improving local circulation to the eyes, thereby potentially reducing intraocular pressure and promoting ocular health.

26) Dhatukshaya (Dhatuksaya, Dhatu-kshaya):
Dhatu-kshaya refers to the degeneration or depletion of tissues. In the context of glaucoma, it represents changes in the optic nerve head resulting from ischemia, hypoperfusion, or elevated intraocular pressure, contributing to progressive optic nerve damage and visual field loss.

27) Inflammation:
Inflammation is a significant factor in the pathology of glaucoma. The text discusses Ayurvedic herbal formulations known for their anti-inflammatory properties, which may help in managing glaucoma by reducing oxidative stress and protecting against vision loss.

28) Kaphadosha (Kaphadosa, Kapha-dosha):
[see source text or glossary: Kaphadosha]

29) Apatarpana:
Apatarpana in Ayurveda signifies therapeutic fasting or adopting a light diet to eliminate excess doshas. Specifically, Kaphashodhana protocols use Apatarpana to promote the balance of Kapha-dosha, reducing ocular conditions like Adhimantha that resemble glaucoma.

30) Abhishyanda (Abhisyanda):
Abhisyanda is an Ayurvedic term relating to inflammatory eye conditions. The text mentions its treatment protocols as effective for Adhimantha, underlining the holistic management approach for ocular health that includes fasting, medicated applications, and cleansing therapies.

31) Saptamrita (Saptamrta, Sapta-amrita):
[see source text or glossary: Saptamrita]

32) Patanjali:
Patanjali refers to Patanjali Bhartiya Ayurvigyan evam Anusandhan Sansthan, the institution where the authors are affiliated. It underscores the academic and research foundation behind the study of Ayurvedic approaches to managing primary open-angle glaucoma (POAG).

33) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic herbal formulation known for its antioxidant and anti-inflammatory properties. The text acknowledges its potential benefits in reducing oxidative stress and improving ocular blood flow in individuals with primary open-angle glaucoma (POAG).

34) Bidalaka:
Bidalaka in Ayurveda refers to the application of medicated pastes on the eyes. It is included in the therapeutic steps for managing Adhimantha, an Ayurvedic condition analogous to glaucoma, designed to pacify Kapha-dosha and promote ocular health.

35) Rasayani:
[see source text or glossary: Rasayani]

36) Langhana (Lamghana):
Langhana signifies therapeutic fasting in Ayurveda. It is part of the treatment regimen for managing ocular conditions like Adhimantha, by eliminating excess doshas such as Kapha, and helping in the overall balance and health of the body and eyes.

37) Kaphaja:
Kaphaja refers to the subtype of Adhimantha associated with primary open-angle glaucoma (POAG). The text describes how Kaphaja Adhimantha closely resembles POAG in terms of symptoms and necessitates specific treatments aimed at balancing Kapha-dosha.

38) Alepana:
Alepana in Ayurveda involves applying medicated substances externally on the body or eyes. For ocular conditions like Adhimantha, it forms part of the therapeutic regimen for easing symptoms and improving overall ocular health.

39) Shopha (Sopha):
Shopha in Ayurvedic terms indicates swelling or elevated intraocular pressure. The text describes how conditions like Adhimantha, analogous to glaucoma, present with elevated IOP among other symptoms, necessitating specific therapeutic interventions.

40) Kshaya (Ksaya):
[see source text or glossary: Kshaya]

41) Kavala:
Kavala in Ayurveda involves gargling with medicated liquids. It is one of the steps in the Kaphashodhana therapy, which aims to cleanse the head and improve ocular health, particularly in cases resembling primary open-angle glaucoma (POAG).

42) Kapha:
Kapha is one of the three primary doshas in Ayurveda, responsible for stability and structure in the body. Imbalance in Kapha is implicated in ocular conditions like Adhimantha, analogous to primary open-angle glaucoma (POAG), directing the therapeutic approach to rebalancing Kapha.

43) Nasya (Nashya):
Nasya involves the nasal administration of medicated substances in Ayurveda. It is used as part of the therapeutic protocol for managing Adhimantha, which includes primary open-angle glaucoma (POAG), by targeting and cleansing the head region.

44) Gupta:
[see source text or glossary: Gupta]

45) Tivra:
[see source text or glossary: Tivra]

46) Lauha:
[see source text or glossary: Lauha]

47) Nasa (Nasha):
[see source text or glossary: Nasha]

48) Hrasa:
[see source text or glossary: Hrasa]

49) Ayus (Ayush):
Ayush refers to the collective disciplines of Ayurveda, Yoga, Unani, Siddha, and Homeopathy, representing traditional Indian systems of medicine. The text explores the Ayurveda component of AYUSH in managing primary open-angle glaucoma (POAG).

50) Sanga (Samga, Shanga, Shamga):
[see source text or glossary: Sanga]

51) Hani:
[see source text or glossary: Hani]

52) Beta:
[see source text or glossary: Beta]

53) Diet:
Diet is a significant aspect of Ayurvedic lifestyle modifications for managing ocular health. The text suggests dietary changes as part of the treatment protocol for conditions like Adhimantha, aiming to balance doshas and reduce the progression of primary open-angle glaucoma (POAG).

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Management of Primary Open Angle Glaucoma: Ayurvedic vs. Modern’. Further sources in the context of Science might help you critically compare this page with similair documents:

Raktamokshana, Adhimantha, Lifestyle modification, Ayurvedic treatment, Chakshushya Rasayana, Primary open angle glaucoma, Intraocular pressure, Optic nerve damage, Visual field loss, Therapeutic approaches, Neuroprotection Strategies.

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