Evaluation of Antibacterial Activity of Hinguleshwar Rasa
Journal name: Ayushdhara
Original article title: Evaluation of Antibacterial Activity of Hinguleshwar Rasa
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Deepika Upadhyay
Lecturer, Dept. of Rasashastra & B.K, M.J.F. Chomu College, Jaipur.
Om Prakash Gupta
Medical Officer, Dept. of Ayurveda, Bhilwara, Rajasthan.
K. Shankar Rao
Professor & H.O.D. Dept. of Rasashastra & B.K. N.I.A. Jaipur, Rajasthan, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Evaluation of Antibacterial Activity of Hinguleshwar Rasa
Year: 2023 | Doi: 10.47070/ayushdhara.v10i2.1202
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
The rise of infectious diseases continues to challenge humanity, prompting an increased reliance on antibiotics. However, the overuse and misuse of these synthetic medications have led to significant microbial resistance, necessitating the search for new antibacterial agents. This study focuses on Hinguleshwar Rasa, a traditional Ayurvedic preparation known for its clinical efficacy against various infections. By examining its antibacterial activity against several pathogenic bacteria, this research aims to validate the medicinal properties of this classical formulation through in vitro culture and sensitivity tests.
Antibacterial Efficacy of Hinguleshwar Rasa
One key aspect of the study was the evaluation of the antibacterial activity of Hinguleshwar Rasa against well-known pathogenic bacteria, including Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhi. Utilizing the well diffusion method, different concentrations of the preparation (50, 100, 125 mg/ml) were tested in comparison to streptomycin as a control. The study found that Hinguleshwar Rasa exhibited a notable inhibitory effect, especially against Salmonella typhi and Streptococcus pyogenes, demonstrating the potential of this traditional medicine as a viable alternative in the face of growing antimicrobial resistance.
Comparative Analysis with Standard Antibiotics
The study involved comparing the zones of inhibition observed for Hinguleshwar Rasa with those of streptomycin. Results indicated that varying concentrations of Hinguleshwar Rasa displayed different levels of antibacterial sensitivity, with Pseudomonas aeruginosa and Streptococcus pyogenes showing high sensitivity to the preparation. In contrast, E. coli exhibited moderate sensitivity. This differential response underscores the complexity of the antimicrobial properties and suggests that certain pathogens may react more favorably to this Ayurvedic concoction, warranting further investigation into the mechanisms at play.
Conclusion
The preliminary findings from this study suggest that Hinguleshwar Rasa possesses significant antibacterial properties against a range of pathogenic bacteria, supporting its traditional use in Ayurvedic medicine. The results advocate for more comprehensive research to elucidate the precise mechanisms and effectiveness of this preparation. Given the alarming rise of antibiotic resistance globally, Hinguleshwar Rasa offers a promising avenue for developing alternative therapeutic strategies rooted in traditional healing practices. This reflection reinforces the importance of integrating ancient knowledge with contemporary scientific validation to enhance healthcare approaches.
FAQ section (important questions/answers):
What is the aim of the study on Hinguleshwar Rasa?
The study aims to evaluate the antibacterial activity of Hinguleshwar Rasa against common pathogenic bacteria, providing scientific validation for its traditional medicinal use.
Which bacteria were tested for antibacterial activity?
The antibacterial activity was tested against Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhi using the well diffusion method.
What were the results of the antibacterial activity tests?
The study found that Hinguleshwar Rasa exhibited significant antibacterial effects, particularly against Salmonella typhi and Streptococcus pyogenes, with varying sensitivity levels across different bacterial strains.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Evaluation of Antibacterial Activity of Hinguleshwar Rasa”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Rasa (Rasha):
Rasa refers to the Ayurvedic formulation used for treating various conditions like infections and diseases. In this document, Hinguleshwar Rasa is evaluated for its antibacterial activity and effectiveness against different bacteria. It is a preparation from Ayurveda texts [see source text or glossary: Rasa].
2) Aureus:
Staphylococcus aureus is one of the bacterial strains tested for antibiotic resistance in this study. It showed varying degrees of sensitivity to Hinguleshwar Rasa at different concentrations, highlighting the formulation's potential effectiveness against such pathogens.
3) Drug:
In the context of this study, drug refers to Hinguleshwar Rasa, an Ayurvedic preparation, being evaluated for its antibacterial properties. It is assessed for its inhibitory effects against common pathogenic bacteria, providing a potential alternative treatment to conventional antibiotics.
4) Blood:
Blood agar is used as a culture medium to grow certain types of bacteria. In this study, it is used for evaluating the antibacterial activity of Hinguleshwar Rasa by providing a suitable environment for Streptococcus pyogenes to grow so that inhibition zones can be measured.
5) Medicine:
In this context, medicine refers to traditional Ayurvedic formulations such as Hinguleshwar Rasa, used to manage infections and other health issues. Its antibacterial properties are evaluated to provide a scientific basis for its traditional use [see source text or glossary: Medicine].
6) Rasashastra (Rasa-shastra, Rasasastra):
Rasashastra is the branch of Ayurveda focused on the preparation of medicines using minerals and metals. Hinguleshwar Rasa, studied here, is one such formulation derived from Rasashastra texts for treating various ailments, including infections.
7) Jaipur:
Jaipur, a city in India, is where significant parts of this study and research on Hinguleshwar Rasa were conducted. It's also home to the institutions and contributors involved, like the NIA Jaipur and M.J.F. Chomu College.
8) Gupta:
Om Prakash Gupta is one of the authors of the study evaluating the antibacterial activity of Hinguleshwar Rasa. He is affiliated with the Department of Ayurveda in Bhilwara, Rajasthan, contributing to the research publication.
9) Fever:
Fever is one of the conditions that Hinguleshwar Rasa is traditionally used to manage in Ayurvedic medicine. The study includes bacteria that cause fever, highlighting the formulation's potential for treating febrile infectious diseases.
10) Rajasthan:
Rajasthan is the state in India where the research related to Hinguleshwar Rasa took place. Institutions and authors mentioned, such as Om Prakash Gupta and the Chemind Diagnosis and biosolution lab, are based in Rajasthan.
11) Disease:
In the context of this study, disease refers to infections and conditions like enteric fever, rheumatoid arthritis, and abdominal disorders that Hinguleshwar Rasa aims to treat. The research evaluates its antibacterial effectiveness to support its usage against such diseases.
12) Glass:
Glass refers to the sterilizable type of glassware used in the study, such as test tubes and petri dishes, required for preparing culture media and conducting experiments to evaluate the antibacterial activity of Hinguleshwar Rasa.
13) Rheumatoid arthritis:
Rheumatoid arthritis, or Amavata in Ayurveda, is one of the conditions for which Hinguleshwar Rasa is traditionally used. The study assesses the antibacterial properties of the formulation, potentially mitigating infections that may exacerbate rheumatoid arthritis.
14) Piper longum:
Piper longum, or Pippli, is an ingredient in Hinguleshwar Rasa. This spice is used in various Ayurvedic formulations and its inclusion in the preparation is evaluated for its contribution to the compound's overall antibacterial activity.
15) Antibiotic (Antibacterial):
Anti-bacterial refers to the ability to prevent bacterial growth. The study aims to evaluate the antibacterial activity of Hinguleshwar Rasa, determining its effectiveness against pathogenic bacteria strains like Streptococcus pyogenes and Staphylococcus aureus.
16) Bhaishajya (Bhaisajya):
Bhaishajya Ratnawali is one of the classical Ayurvedic texts that mentions Hinguleshwar Rasa. The formula used in this study is derived from this text, supporting the traditional usage of this preparation in treating various diseases.
17) Vatsanabha (Vatsa-nabha):
Vatsanabha, or purified Aconitum ferox, is an ingredient in the Ayurvedic formulation Hinguleshwar Rasa. This herb is known for its potent properties and is included in the study for its potential antibacterial effects.
18) Discussion:
In the discussion section, the study elaborates on the observed antibacterial effects of Hinguleshwar Rasa. It highlights the varying sensitivities of different bacteria to the formulation, suggesting potential therapeutic applications and the need for further analysis.
19) Rasayoga (Rasa-yoga):
Rasa-yoga, in this context, refers to the classical Ayurvedic formulation mentioned in texts. Hinguleshwar Rasa is one such formula selected for the study to evaluate its antibacterial properties, demonstrating the ancient wisdom of Rasa-yoga practices.
20) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine. This study evaluates Hinguleshwar Rasa, a traditional Ayurvedic drug, for its antibacterial activity, aiming to validate its effectiveness scientifically and integrate Ayurvedic treatments with modern medicine.
21) Vikriti (Vikrti):
Vikriti refers to disorders or pathologies in Ayurveda. Hinguleshwar Rasa is traditionally used to manage various vikriti such as hepato-splenomegaly (Yakrit Pliha vikriti), demonstrating its broad therapeutic applications in Ayurvedic medicine [see source text or glossary: Vikriti].
22) Hingula (Himgula):
Hingula, or cinnabar, is a crucial ingredient in the formulation of Hinguleshwar Rasa. This mineral is known for its medicinal properties in Ayurveda and is evaluated for its antibacterial effects in this study.
23) Amavata (Ama-vata):
Amavata, or rheumatoid arthritis, is one of the conditions Hinguleshwar Rasa is traditionally used to treat. The study assesses the formulation's antibacterial activity, which might contribute to reducing inflammation associated with bacterial infections.
24) Yakrit (Yakrt):
Yakrit refers to the liver in Ayurveda. Hinguleshwar Rasa is used traditionally for treating hepato-splenomegaly (Yakrit Pliha vikriti), demonstrating its therapeutic application in liver-related disorders and its antibacterial properties in this study [see source text or glossary: Yakrit].
25) Ajirna:
Ajirna, or indigestion, is one of the ailments that Hinguleshwar Rasa aims to manage according to Ayurvedic texts. The study assesses its antibacterial activity, providing insight into its potential effectiveness in treating digestive issues related to infections [see source text or glossary: Ajirna].
26) Nature:
The nature of antimicrobial activity refers to how Hinguleshwar Rasa interacts with different bacterial strains. The study observes that its antibacterial efficacy varies with concentration, shedding light on its potential as a natural remedy against infections [see source text or glossary: Nature].
27) Animal:
Animal tissue is a component of the nutrient broth used for bacterial cultures in this study. This nutrient medium provides the necessary environment for the growth of microorganisms, enabling the evaluation of Hinguleshwar Rasa's antibacterial activity [see source text or glossary: Animal].
28) Cotton:
Cotton is used for sterilization purposes in the study, such as plugging flasks during autoclaving. It helps maintain a sterile environment, ensuring the accuracy of the antibacterial activity evaluation of Hinguleshwar Rasa [see source text or glossary: Cotton].
29) Pliha:
Pliha in Ayurveda refers to the spleen. Yakrit Pliha vikriti (hepato-splenomegaly) is a disorder treated with Hinguleshwar Rasa, as mentioned in the study, which evaluates its antibacterial properties linked to spleen-related infections [see source text or glossary: Pliha].
30) India:
India is the country where this study on Hinguleshwar Rasa was conducted. It is home to Ayurveda, the traditional medical system that's the foundation for the formulation and evaluation of this antibacterial preparation.
31) Ayus (Ayush):
AYUSH stands for Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homeopathy. The journal AYUSHDHARA publishes research on these traditional systems, including the study evaluating the antibacterial activity of the Ayurvedic formulation Hinguleshwar Rasa.
32) Roga:
Roga means disease in Ayurveda. Hinguleshwar Rasa, evaluated in this study, is traditionally used to manage various rogas like enteric fever (antrik jwara) and abdominal disorders (udar roga), showcasing its therapeutic potential [see source text or glossary: Roga].
33) Yoga:
Yoga, while often associated with physical postures, encompasses a broader domain in Ayurveda, such as preparations and practices. Rasa-yoga in the study refers to intricate formulations like Hinguleshwar Rasa used for various treatments [see source text or glossary: Yoga].
Other Science Concepts:
Discover the significance of concepts within the article: ‘Evaluation of Antibacterial Activity of Hinguleshwar Rasa’. Further sources in the context of Science might help you critically compare this page with similair documents:
Research work, Antibacterial activity, In vitro, Zone of inhibition, Pathogenic bacteria, Antimicrobial Resistance, Well diffusion method, Culture and Sensitivity Test, Hinguleshwar Rasa, DMSO solution, Nutrient media.