Artificial Intelligence and Challenges in Ayurveda Pharmaceutics: A Review
Journal name: Ayushdhara
Original article title: Artificial Intelligence and Challenges in Ayurveda Pharmaceutics: A Review
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Bale Anura
Principal, professor and HOD, Department of Kriya Sharir, Gomantak Ayurveda Mahavidyalaya & Research Centre, Vazem, Shiroda, Goa, India
Desai Gaurav
HOD, Department of Agada tantra vyavahara ayurved evum vidhi vaidyak, Gomantak Ayurveda Mahavidyalaya & Research Centre, Vazem, Shiroda, Goa, India
Khedekar Sumod
I/C-HOD, Department of Kaumarbhritya-balrog (Ayu-pediatrics), Gomantak Ayurveda Mahavidyalaya & Research Centre, Vazem, Shiroda, Goa, India
Nayak Meghna
Intern, Gomantak Ayurveda Mahavidyalaya & Research Centre, Vazem, Shiroda, Goa, India
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Artificial Intelligence and Challenges in Ayurveda Pharmaceutics: A Review
Year: 2022 | Doi: 10.47070/ayushdhara.v9i1.825
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Ayurveda, an ancient medical system, aims to enhance quality of life and longevity through holistic health approaches. With its extensive pharmaceutical practices involving numerous combinations for treating various ailments, the system is gaining global prominence due to its safety and efficacy. However, as demand increases, there is a pressing need to modernize Ayurveda Pharmaceutics. Artificial Intelligence (AI) emerges as a transformative tool in this regard, offering innovative solutions to improve drug development, efficacy, and quality assurance, thereby aligning Ayurveda with contemporary scientific standards.
The Role of AI in Drug Discovery
Artificial Intelligence significantly enhances drug discovery within Ayurveda by addressing challenges related to efficiency and efficacy. The integration of AI allows for the analysis of vast amounts of historical and current data, fostering the identification of herbal drugs through their chemical and pharmacological properties. AI assists in categorizing classical Ayurvedic drugs, detailing their botanic characteristics, and correlating them with modern therapeutic applications. By utilizing data from research articles, clinical trials, and classical texts, AI can identify patterns and suggest alternative medications for various diseases, thereby expediting the drug development process.
Quality Control and Standardization Challenges
One of the major challenges in Ayurveda Pharmaceutics is ensuring the quality, safety, and standardization of medicinal formulations. The use of AI in the Rasa-shastra (a branch of Ayurveda focused on preparation of metal and mineral-based medicines) can enhance quality control by developing standard protocols and innovative methodologies to analyze and ensure safety and efficacy. AI-enabled tools can help formalize testing methods for formulations like Bhasmas and Rasaushadhis, bridging the gap between traditional practices and modern scientific requirements. This evolves the field towards greater accountability and international acceptance of Ayurvedic products.
Conclusion
The incorporation of Artificial Intelligence in Ayurveda Pharmaceutics holds substantial promise for addressing the critical challenges of drug availability, quality assurance, and formulation efficacy. By blending traditional knowledge with modern technological advancements, AI facilitates the revitalization of Ayurveda within the global healthcare domain, ensuring it meets contemporary demands and standards. As Ayurveda continues to garner recognition worldwide, the strategic integration of AI could pave the way for its advanced application and acceptance, fostering a holistic understanding of health and wellness rooted in ancient wisdom.
FAQ section (important questions/answers):
What is the main objective of Ayurveda as a traditional medicine?
The main objective of Ayurveda is to prolong human lifespan and promote positive health. It focuses on maintaining balance in the body and using tailored treatments to address various ailments, emphasizing holistic well-being.
How can Artificial Intelligence improve Ayurveda Pharmaceutics?
Artificial Intelligence can enhance quality control, standardization, and efficiency in drug development within Ayurveda. It can aid in automating processes, improving decision-making, identifying medicinal properties, and accelerating the drug discovery process.
What challenges does Ayurveda face in modern medical practice?
Ayurveda faces challenges such as lack of empirical evidence, quality assurance, and standardized treatments. The increasing global acceptance of Ayurveda necessitates reform and modernization to align with contemporary scientific standards and practices.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Artificial Intelligence and Challenges in Ayurveda Pharmaceutics: A Review”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine that focuses on maintaining positive health and treating various ailments based on fundamental principles and theory-based practices established over many centuries. It becomes increasingly accepted worldwide due to its safety and efficacy.
2) Drug:
In Ayurveda, a drug refers to a substance derived from plants, animals, or minerals that undergo specific processing to become a palatable medicinal product used for treating various conditions.
3) Medicine:
Ayurvedic medicine plays a critical role in patient management, offering a broad range of formulations like syrups, creams, capsules, and more to treat a variety of ailments using classical preparation methods.
4) Disease:
Ayurvedic principles focus on addressing the root cause of diseases through personalized treatment plans based on the individual's constitution, aiming to balance the body's natural forces to restore health.
5) Knowledge:
Knowledge in Ayurveda integrates traditional wisdom with modern research methodologies, which is essential for its global acceptance and the effective application of its principles.
6) Prakriti (Prakrti):
Prakriti is a fundamental concept in Ayurveda; it represents an individual's unique physical and mental constitution, influenced by the balance of the three Doshas, and helps determine personalized treatment plans.
7) Ayus (Ayush):
AYUSH (Ayurveda, Yoga, Unani, Siddha, and Homoeopathy) is a government initiative in India aimed at promoting traditional medical practices, with an emphasis on integrating them into mainstream healthcare.
8) Indian:
Indian Ayurveda forms part of the broader Ayurvedic Pharmacopoeia of India, which sets quality standards for Ayurvedic drugs and formulations to ensure safety and efficacy and is governed by the Department of AYUSH.
9) Dosha (Dosa):
Dosha refers to the three vital energies (Vata, Pitta, and Kapha) in Ayurveda that govern an individual's health and constitution; imbalances in these Doshas are believed to cause diseases.
10) India:
India is the birthplace of Ayurveda, and its governmental and institutional support for the practice and research of Ayurveda plays a pivotal role in its development and global recognition.
11) Science (Scientific):
Though traditionally rooted, Ayurveda now integrates scientific methodologies, including artificial intelligence, to validate its age-old practices and enhance its credibility and acceptance globally.
12) Samhita:
Samhita refers to the classical texts of Ayurveda, such as Charaka Samhita and Sushruta Samhita, which contain extensive knowledge on medical practices, herbal formulations, and treatments.
13) Sanskrit:
Sanskrit is the classical language in which foundational Ayurvedic texts like the Samhitas are written, and it plays a crucial role in preserving and interpreting Ayurveda's rich heritage.
14) Rudra:
RUDRA (Random Uninterrupted Documentation for Retrospective Analysis) is a clinical research program aimed at documenting Ayurvedic clinical practices to generate data on safety and effectiveness.
15) Rasa (Rasha):
Rasa in Ayurveda refers to the taste of a substance and its initial interaction with the body, influencing the medicinal properties and therapeutic effects of herbs and formulations.
16) Pharmacological:
Pharmacological studies in Ayurveda involve analyzing the medicinal properties, dosage, and mode of action of various herbal and mineral compounds to ensure they meet modern safety and efficacy standards.
17) Kalpana:
Bhaishajya Kalpana in Ayurveda refers to the pharmaceutical processes involved in preparing various types of medicinal formulations, ensuring they are safe, effective, and palatable.
18) Bhasma (Bhasman):
Bhasma are Ayurvedic preparations made from purified minerals and metals, processed into ash form, known for their fast action and low dosages in treating various ailments.
19) Family:
The concept of Family in Ayurveda likely pertains to plant families from which medicinal herbs are selected and classified, ensuring the proper identification and usage in formulations.
20) Nature:
Nature in Ayurveda describes the inherent qualities and properties of substances used in medicine, underscoring the natural origins of Ayurvedic drugs derived primarily from plants, animals, and minerals.
21) Dhara:
DHARA (Digital Helpline for Ayurveda Research Articles) is an internet indexing service for Ayurvedic research articles, providing researchers with comprehensive access to data and publications.
22) Nayak:
Meghna Nayak is one of the authors of the reviewed article, contributing to the research on artificial intelligence and its applications in Ayurveda pharmaceutics.
23) Pune:
Pune is mentioned in relation to the development of AyuSoft, an interactive software for medical solutions based on traditional medicine, developed in collaboration with various institutions including CDAC Pune.
24) New Delhi:
New Delhi is referenced in relation to DHARA, a project initiated by Central Council for Research in Ayurvedic Science (CCRAS) based in India’s capital city, providing vital indexing services for Ayurvedic articles.
25) Pharmacology:
Pharmacology in Ayurveda integrates the understanding of drug actions, interactions, and therapeutic uses, aligning traditional practices with modern scientific standards to validate and enhance treatment efficacy.
26) Rasashastra (Rasa-shastra, Rasasastra):
Rasa-shastra is the ancient Ayurvedic science focusing on the preparation of mineral and metal-based medicines, blending alchemical methods with therapeutic practices to enhance drug potency and reduce toxicity.
27) Rasaushadhi (Rasa-aushadhi, Rasausadhi):
Rasaushadhi refers to a category of Ayurvedic formulations that include processed metals and minerals, typically used in highly refined forms like bhasmas, known for their potent therapeutic effects.
28) Bhaishajya (Bhaisajya):
Bhaishajya Kalpana is the pharmaceutical branch of Ayurveda, dealing with the preparation, storage, and standardization of Ayurvedic drugs and formulations to ensure they are safe and effective.
29) Substance:
In Ayurveda, a substance can refer to any plant, animal, or mineral product that undergoes specific processing to be used as a medicinal drug, tailored to treat various conditions.
30) Aushadha (Ausadha):
Aushadha, or medicine, in Ayurveda is derived from natural sources and processed according to traditional methods to maintain health and treat diseases, reflecting the system's herbal-centric approach.
31) Darshana (Darsana):
Darshana refers to the six classical schools of Indian philosophy that underpin the theoretical foundations of Ayurveda, particularly the logic of Sankhya and Nyāya-Vaisheshika.
32) Language:
Language, specifically Sanskrit, plays a crucial role in Ayurveda as it is the medium through which ancient texts and formulations are documented, preserving the rich heritage and knowledge of this medicinal system.
33) Kashaya (Kasaya):
Kashaya is one of the basic classical forms in Ayurveda known as Panchavidha Kashaya Kalpana, representing a decoction form of medicine derived from various herbs for therapeutic use.
34) Siddha:
Siddha is one of the traditional Indian medical systems included under the AYUSH umbrella, similar to Ayurveda, focusing on holistic health and natural therapies.
35) Cancer:
Cancer is one of the chronic diseases mentioned in the reviewed article that Ayurveda claims to address effectively, highlighting the system's potential in treating conditions that may be less responsive to allopathic treatments.
36) Kosha (Kosa):
Kosha, likely referring to a dictionary or glossary of Ayurvedic terms, aids practitioners and researchers in understanding the terminology and concepts fundamental to Ayurvedic medicine.
37) Delhi:
Delhi, referenced in relation to the Central Council for Research in Ayurvedic Science (CCRAS) and its digital initiatives, plays a key role in advancing Ayurvedic research and access to scholarly articles.
38) Cloud:
Cloud technology is utilized in platforms like AyushEHR, which offers cloud-based Electronic Health Record (EHR) solutions tailored for Ayurveda, integrating data management and healthcare delivery.
39) Vati:
Vati refers to Ayurvedic tablets or pills made by combining powdered herbs and other ingredients, which are pressed into a pill form for easy administration and dosing.
40) Thiruvananthapuram (Thiruvanantha-puram, Tiru-anantapuram, Tiruvanantapuram, Tiruananta-puram):
Thiruvananthapuram is noted for its association with the development of the RASEX software, designed to match pharmacological features with therapeutic properties in Ayurvedic medicine.
41) Sushruta-samhita (Susruta-samhita):
Sushruta Samhita is a seminal text in Ayurveda that covers surgical techniques, medicinal uses of herbs, and treatment protocols, authored by the ancient sage Sushruta.
42) Ashtangasamgraha (Astangasamgraha, Astangasangraha, Ashtanga-samgraha, Ashtanga-sangraha, Ashtangasangraha):
Ashtanga Samgraha is one of the classical Ayurvedic texts that provides detailed insights into the principles, practices, and formulations used in Ayurveda, forming a foundational reference for practitioners.
43) Ashtangahridaya (Astangahrdaya, Ashtanga-hridaya):
Ashtanga Hridaya is a classical Ayurvedic compendium that synthesizes earlier texts like Charaka Samhita and Sushruta Samhita, providing practical guidelines for diagnosis, treatment, and maintaining health.
44) Candraprabha (Candra-prabha):
Perhaps referring to ‘Chandraprabha Vati’, an Ayurvedic formulation used for treating various ailments, including issues related to urinary and reproductive systems, known for its efficacy in small doses.
45) Agadatantra (Agada-tantra, Agadatamtra):
Agada-tantra is a branch of Ayurveda that deals with toxicology, focusing on the diagnosis, treatment, and prevention of poisoning and the toxic effects of various substances.
46) Triskandha (Tri-skandha):
Triskandha likely refers to a classification system in Ayurveda that categorizes information based on causes, signs, and medicinal treatments, facilitating more systematic research and practice.
47) Vyavahara:
Vyavahara refers to the practical application of Ayurvedic principles in everyday life and patient care, focusing on conduct and behaviors essential for maintaining health and treating diseases.
48) Education:
Education in Ayurveda involves a thorough understanding of classical texts, medicinal preparations, diagnosis, and treatment methods to effectively apply its principles in contemporary healthcare settings.
49) Prabhava:
Prabhava is an Ayurvedic term used to describe the specific, often unique, therapeutic potency or effect of a substance that cannot be explained by its basic qualities (Rasa, Guna, Virya, Vipaka).
50) Lakshana (Laksana):
Lakshana in Ayurveda refers to the signs and symptoms of diseases, which are meticulously documented to aid in accurate diagnosis and formulation of effective treatment plans.
51) Ashtanga (Astanga, Ashtan-anga):
Ashtanga refers to the eight branches of Ayurveda that encompass various aspects of health and medicine, including surgery, pediatrics, toxicology, and rejuvenation, providing a holistic approach to wellness.
52) Toxicity:
Toxicity studies in Ayurveda assess the safety of herbal and mineral medicines, ensuring they do not cause adverse effects and are safe for therapeutic use.
53) Shastra (Sastra):
Shastra refers to the Ayurvedic scriptures or specialized fields of study, such as Rasashastra or Agada-tantra, that provide detailed knowledge and guidelines for medical practice and formulation.
54) Guggulu:
Guggulu is a resin used in various Ayurvedic formulations known for its anti-inflammatory, anti-lipid, and rejuvenating properties, often included in compound preparations like Mahayogaraj Guggulu.
55) Abhraka:
Abhraka is the Sanskrit name for Biotite mica, used in Ayurvedic medicine after purification and processing into a bhasma, known for its therapeutic benefits in respiratory and reproductive health.
56) Samkhya (Sankhya, Shankhya):
Sankhya is one of the six classical Indian philosophies that contribute to the theoretical underpinnings of Ayurveda, particularly influencing its understanding of the universe and human physiology.
57) Suvarna:
Suvarna refers to gold, which is used in Ayurvedic medicine primarily in the form of Suvarna bhasma; it is believed to enhance longevity, strength, and cognitive functions.
58) Mineral:
Mineral substances are extensively used in Ayurvedic formulations, especially in Rasaushadhis, where they are processed into bioavailable forms like bhasmas to treat various ailments effectively.
59) Tantra (Tamtra, Tantrism):
Tantra in Ayurveda refers to specialized knowledge systems or techniques, including Agada-tantra (toxicology) and Rasashastra (alchemy), focusing on specific aspects of health and medicine.
60) Rajata:
Rajata is the Sanskrit term for silver, utilized in Ayurvedic medicine in processed forms like bhasma for its antimicrobial and rejuvenating properties.
61) Vipaka:
Vipaka refers to the post-digestive effect of a substance in Ayurveda, influencing its ultimate impact on the body's physiology and contributing to its therapeutic properties.
62) Jaipur:
Jaipur is mentioned in the context of institutions like the National Institute of Ayurveda participating in initiatives like RUDRA for systematic clinical documentation and research.
63) Phanta (Phamta):
Phanta is a decoction prepared by infusing herbs in hot water, one of the basic forms of Ayurvedic preparations known as Panchavidha Kashaya Kalpana.
64) Debate:
The text suggests future debates on reviving Ayurveda and addressing contemporary challenges, integrating AI and modern methodologies to enhance its global acceptance and scientific validation.
65) Silver:
Silver is used in Ayurveda in its purified form, commonly as Rajata bhasma, for its therapeutic benefits, including antimicrobial, anti-inflammatory, and rejuvenating properties.
66) Animal:
Animal products are used in Ayurvedic medicine, processed and purified according to traditional methods to be incorporated into formulations for their unique therapeutic properties.
67) Desire:
There is a call for deeper intellectual engagement among scholars to understand and convey the scientific intricacies of Ayurveda, ensuring its principles and practices are accurately interpreted and applied.
68) Agada:
Agada refers to a branch of Ayurveda dealing with toxicology, addressing the diagnosis and treatment of poisonings and maintaining health through specific detoxifying herbal formulations.
69) Kriya:
Kriya in Ayurveda refers to actions or treatments, especially those aimed at balancing the body's doshas and restoring health through therapeutic practices.
70) Nyaya:
Nyaya is one of the classical Indian Darshanas that provides logical and systematic methods for understanding and explaining the principles of Ayurveda, contributing to its theoretical foundations.
71) Kalpa:
Kalpa likely refers to the formulations or procedures in Ayurveda, such as Panchavidha Kashaya Kalpana, which provide structured methodologies for preparing effective medicinal compounds.
72) Vidhi:
Vidhi relates to the procedures or rules in Ayurveda for preparing and administering treatments, ensuring that practices are followed consistently for effective therapeutic outcomes.
73) Kalka:
Kalka is one of the classical forms of Ayurvedic preparations where herbs are ground into a paste, commonly used as a base for other formulations or applied directly for therapeutic effect.
74) Desha (Desa):
Desha in Ayurveda refers to the geographical region, which influences the choice of medicinal plants and formulations based on the local climate and ecosystem.
75) Jnana:
Jnana Prabodhini, an NGO based in Pune, India, is involved in developing AyuSoft, demonstrating the integration of modern technology and traditional knowledge to improve Ayurvedic medical practices.
[Note: The above list is limited to 75. Total glossary definitions available: 85]
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