Efficacy of Unani Drug for Managing Gastroesophageal Reflux Disease
Journal name: Ayushdhara
Original article title: Clinical Efficacy of Unani Drug in the Management of Tabkheer-I-Meda (Gastroesophageal Reflux Disease)
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Original source:
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Najmus Sehar
Research officer, CCRUM, New Delhi, India.
Khan Mohammad Nafees
Deputy Director, CCRUM, New Delhi India.
Salam Mahboob
Research officer (U), CCRUM, New Delhi India.
Naeem Mohd
Research officer (Bio. Chem.), CCRUM, New Delhi India.
Akhtar Jamal
Research officer (U), CCRUM, New Delhi India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Clinical Efficacy of Unani Drug in the Management of Tabkheer-I-Meda (Gastroesophageal Reflux Disease)
Year: 2021 | Doi: 10.47070/ayushdhara.v8i4.765
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
The article discusses the clinical efficacy of the Unani drug Safoof-i-Tabkheer in managing Tabkheer-i-Meda, which corresponds to Gastro-esophageal Reflux Disease (GERD) in modern medicine. Tabkheer-i-Meda is characterized by symptoms such as indigestion, abdominal pain, burning sensations in the epigastrium, anorexia, nausea, and acid reflux. The study aimed to evaluate the effectiveness and safety of Safoof-i-Tabkheer, an Unani pharmacopoeial formulation, in alleviating the associated symptoms of this condition among patients receiving the treatment.
Ongoing Improvements in Symptoms
One notable outcome of the study was the significant reduction in key symptoms associated with Tabkheer-i-Meda following the administration of Safoof-i-Tabkheer. After treatment, symptoms such as retrosternal burning, acidic brash, epigastric pain, and anorexia showed high percentage reductions of 53.89%, 51.56%, 48.53%, and 40.65%, respectively, compared to baseline measurements. Statistical analysis confirmed that these improvements were highly significant (p < 0.001), suggesting that the observed therapeutic effects were indeed attributable to the Unani formulation. The ingredients in Safoof-i-Tabkheer, including Badiyan, Kishneez-khushk, Dana-e-Heel, and Tabasheer, contribute carminative, analgesic, and anti-inflammatory properties that work synergistically to relieve symptoms.
Patient Demographics and Study Insights
The study also provided valuable insights into the demographics of patients suffering from Tabkheer-i-Meda. The majority of patients (70%) were female, and the age group primarily affected was 18 to 30 years. The study found that the prevalence of GERD was higher among non-vegetarians and those with sedentary lifestyles, as well as lower socioeconomic status. These findings align with existing literature that suggests dietary habits and lifestyle factors significantly contribute to the risk of GERD. Moreover, irregular bowel habits were noted to correlate with the incidence of the disease, indicating the need for further investigation into its multifactorial origins.
Conclusion
The study concluded that the Unani drug Safoof-i-Tabkheer is both effective and safe for treating Tabkheer-i-Meda, with substantial improvements observed in patients after just one week of treatment. However, due to the limited sample size of 30 patients, the authors recommend conducting further studies with larger populations to validate the findings and enhance understanding of its efficacy. These results highlight the potential of traditional Unani medicine in addressing contemporary health issues such as gastroesophageal reflux disease, warranting more extensive research to explore its broader applications.
FAQ section (important questions/answers):
What is Tabkheer-i-Meda and how is it defined?
Tabkheer-i-Meda refers to the reflux of stomach acid, exhibiting symptoms like indigestion and burning sensation. In modern medicine, it is known as Gastro-esophageal Reflux Disease (GERD), characterized by the abnormal reflux of gastric contents into the esophagus or oral cavity.
What are the key findings from the study on Safoof-i-Tabkheer?
The study demonstrated that Safoof-i-Tabkheer effectively reduced symptoms of Tabkheer-i-Meda, with significant improvements in retrosternal burning, acidic brash, epigastric pain, and anorexia. Adverse effects were not reported, indicating its safety and efficacy as a treatment.
What demographic factors were observed in patients with Tabkheer-i-Meda?
The study found that Tabkheer-i-Meda was more prevalent among younger individuals (ages 18-30) and women. Additionally, lifestyle factors, such as a sedentary lifestyle and non-vegetarian dietary habits, were associated with higher incidence rates of the condition.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of Unani Drug for Managing Gastroesophageal Reflux Disease”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Disease:
Tabkheer-i-Meda, described in Unani literature, corresponds to Gastro-esophageal Reflux Disease (GERD) in modern medicine. It's characterized by acid reflux and symptoms like indigestion, pain, and burning sensation. The study investigates a Unani drug for its management.
2) Medas (Meda, Medash):
Meda refers to the stomach in Unani medicine. Tabkheer-i-Meda is a term used to describe the condition involving acid reflux from the stomach, also known as Gastro-esophageal Reflux Disease (GERD). The study aimed to manage this condition using a Unani drug.
3) Pain:
Tabkheer-i-Meda or GERD is characterized by various symptoms like abdominal pain, among others. The Unani drug Safoof-i-Tabkheer showed significant reduction in epigastric pain, demonstrating its efficacy in managing the pain associated with the disease.
4) Drug:
The study evaluated the clinical efficacy of a Unani drug named Safoof-i-Tabkheer for managing Tabkheer-i-Meda (GERD). The drug was found to be very effective in reducing the symptoms like retrosternal burning, epigastric pain, and acidic brash without any adverse effects.
5) Medicine:
Unani medicine's holistic approach was applied to manage Tabkheer-i-Meda (GERD) using a drug called Safoof-i-Tabkheer. This traditional medical system incorporates dietary and lifestyle recommendations in addition to medicinal formulations.
6) Ulcer:
Types of ulcers like duodenal and peptic ulcers were part of the exclusion criteria in this study to ensure a focused assessment on GERD. This differentiation was crucial to gauge the drug's specific efficacy for Tabkheer-i-Meda (GERD) without confounding variables.
7) Diet:
Diet played a significant role in the prevalence of Tabkheer-i-Meda (GERD). Patients with non-vegetarian habits had higher incidences of the disease, likely due to fatty diets that delay gastric emptying. This study underscores the effect of dietary habits on this condition.
8) Education:
The study found a correlation between lower educational levels and higher prevalence of Tabkheer-i-Meda (GERD). Less educated individuals are more likely to have low-income jobs and unhealthy diets, making them more susceptible to GERD, emphasizing the role of education in health outcomes.
9) Burning sensation:
A primary symptom of Tabkheer-i-Meda (GERD) is a retrosternal burning sensation. The study found that the Unani drug Safoof-i-Tabkheer significantly reduced this burning sensation, indicating its efficacy in managing one of the most uncomfortable symptoms of GERD.
10) New Delhi:
New Delhi is the location of the Central Council for Research in Unani Medicine (CCRUM), which was involved in this study. The research officers and some authors were affiliated with CCRUM, highlighting the institutional support for this research on Unani medicine.
11) Lucknow:
The study was conducted at the Central Research Institute of Unani Medicine (CRIUM) in Lucknow. This location was instrumental in selecting the patient pool and administering the treatment for the observational study on Tabkheer-i-Meda (GERD).
12) Nausea:
Nausea is one of the symptoms associated with Tabkheer-i-Meda (GERD). Although not a primary focus of the study, it is part of the symptomatic profile that was potentially alleviated by the Unani drug Safoof-i-Tabkheer.
13) Delhi:
[see source text or glossary: Delhi]
14) India:
The study was conducted in India, specifically involving institutions in New Delhi and Lucknow. This showcases the country's focus on integrating traditional Unani medicine with contemporary research practices to address conditions like Gastro-esophageal Reflux Disease (GERD).
15) Dana:
Dana is part of the formulation of the Unani drug Safoof-i-Tabkheer. Dana-e-Heel-Khurd (Cardamom) in particular, is known for its carminative properties, aiding in the management of symptoms like heartburn, which is significant in the treatment of Tabkheer-i-Meda (GERD).
16) Food:
The study discusses how certain foods, particularly fatty and non-vegetarian diets, are risk factors for Tabkheer-i-Meda (GERD). Unani medicine also emphasizes dietary management alongside medicinal treatment, thus playing a vital role in overall disease management.
17) Human body:
The Unani formulation Safoof-i-Tabkheer demonstrated no adverse effects on the human body, highlighting its safety. The study focused on the gastrointestinal tract, particularly the impact on stomach and esophageal health in the context of acid reflux.
18) Discussion:
The discussion section of the study elaborates on the efficacy of the Unani drug Safoof-i-Tabkheer, reaffirming that its ingredients effectively reduce symptoms of Tabkheer-i-Meda (GERD). It also covers the demographic, dietary, and lifestyle factors influencing the disease.
19) Alcoholism:
Alcoholism is mentioned as one of the risk factors contributing to the occurrence of Tabkheer-i-Meda (GERD). Unani medicine considers lifestyle factors like alcohol consumption pivotal in the etiology of gastrointestinal diseases.
20) Science (Scientific):
The scientific approach of the study included statistical analysis to affirm the efficacy of Safoof-i-Tabkheer. It provided quantifiable evidence that the Unani drug significantly reduced symptoms of Tabkheer-i-Meda (GERD), grounding traditional medicine in empirical research.
21) Pregnant:
Pregnant and lactating women were excluded from this study. This criterion ensured that the safety assessment of the Unani drug Safoof-i-Tabkheer was conducted without potential risks to maternal and fetal health, adhering to ethical research standards.
22) Ayus (Ayush):
AYUSH refers to the traditional Indian systems of medicine including Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homeopathy. The journal AYUSHDHARA published this study, validating the clinical efficacy of a Unani medicine in managing Tabkheer-i-Meda (GERD).
Other Science Concepts:
Discover the significance of concepts within the article: ‘Efficacy of Unani Drug for Managing Gastroesophageal Reflux Disease’. Further sources in the context of Science might help you critically compare this page with similair documents:
Adverse effect, Anorexia, Historical literature, Statistical analysis, Life-style, Socio-economic status, Clinical efficacy, Gastro Esophageal Reflux Disease, Bowel Habit, Epigastric pain, Unani medicine, Prevalence of GERD, Retrosternal burning, Gastric content.