Anti-bacterial effect of Naaval Kottai Mathirai on urinary pathogens
Journal name: Ayushdhara
Original article title: Anti bacterial effect of siddha preparation naaval kottai mathirai against common urinary pathogens
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Sivakkumar. S
Associate Professor, Department of Gunapadam, National Institute of Siddha, Chennai
Juliet. L
Research officer (Siddha), Siddha Central Research Institute, Arumbakkam, Chennai
Ganapathy. G
PhD Guide/Former Professor, National Institute of Siddha, Chennai
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Anti bacterial effect of siddha preparation naaval kottai mathirai against common urinary pathogens
Year: 2020
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Urinary tract infections (UTIs) pose significant challenges, particularly for patients with type 2 diabetes mellitus, as these infections are more prevalent, severe, and often caused by antibiotic-resistant pathogens. Traditional management typically involves antibiotic therapy, but the consistent recurrence of UTIs complicates treatment. The Siddha system of medicine, which utilizes poly herbal, herbo-mineral, and metallic formulations, offers alternatives that may address both diabetes and UTI effectively. One such preparation, Naaval Kottai Mathirai (NKM), made from the seeds of Syzygium cumini and the leaf juice of Aristolochia bracteolata, has shown promise in exhibiting antibacterial properties against common urinary pathogens.
Antibacterial Activity of Naaval Kottai Mathirai
The study investigated the antibacterial effects of NKM using the disc diffusion method, targeting various pathogens associated with UTIs, particularly in diabetic patients. The results indicated significant zones of inhibition for multiple bacterial strains: Escherichia coli (15 mm), Staphylococcus aureus (17 mm), Bacillus subtilis (14 mm), Klebsiella pneumonia (12 mm), Pseudomonas aeruginosa (12 mm), and Enterococcus faecalis (11 mm). These findings suggest that the active components of NKM exert notable antibacterial activity. The preparation demonstrated effectiveness comparable to the standard drug, streptomycin, confirming its potential as an alternative treatment for UTIs.
Siddha Taste Theory and Its Significance
In the Siddha system, the selection of herbal formulations is influenced by the fundamental taste theory, which posits that different tastes correspond to various therapeutic effects. Specifically, the bitter taste is believed to combat microorganisms and lower blood sugar levels, while astringent tastes act as blood purifiers. The ingredients of NKM contribute to its therapeutic efficacy through this lens; Syzygium cumini provides a strong astringent taste, and Aristolochia bracteolata imparts a bitter flavor. Therefore, according to Siddha principles, NKM is not only suitable for managing diabetes but also beneficial for treating UTIs.
Conclusion
The findings from this study support the use of Naaval Kottai Mathirai as a viable treatment option for patients suffering from both diabetes and urinary tract infections. By demonstrating significant antibacterial activity and aligning with Siddha medicinal principles, NKM stands as a promising formulation in addressing the dual challenge of managing diabetic conditions alongside UTIs. Future research focusing on the exploration of novel antibacterial bioactive molecules within NKM could further enhance its therapeutic potential and efficacy within the realm of Siddha medicine.
FAQ section (important questions/answers):
What is the significance of Naaval Kottai Mathirai in diabetes management?
Naaval Kottai Mathirai is a Siddha herbal preparation effective for managing diabetes and urinary tract infections, particularly in diabetic patients. Its formulation combines ingredients with antibacterial properties, enhancing its effectiveness in treating related complications.
What pathogens does Naaval Kottai Mathirai show effectiveness against?
The study found that Naaval Kottai Mathirai exhibited significant antibacterial effects against common urinary pathogens, including Escherichia coli, Staphylococcus aureus, and Klebsiella pneumonia, among others, demonstrating its potential as a treatment for urinary tract infections.
How was the antibacterial activity of Naaval Kottai Mathirai tested?
The antibacterial activity of Naaval Kottai Mathirai was assessed using the disc diffusion method at various concentrations. The zone of inhibition around the discs was measured, indicating the effectiveness against selected bacterial pathogens.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Anti-bacterial effect of Naaval Kottai Mathirai on urinary pathogens”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Siddha:
Siddha refers to a traditional system of medicine originating in South India. It involves the use of polyherbal, herbo-mineral, and metallic formulations for the treatment of various ailments, including diabetes and urinary tract infections.
2) Antibiotic (Antibacterial):
The term anti-bacterial relates to the ability to inhibit or kill bacteria. In the study, the Siddha preparation Naaval Kottai Mathirai was tested for its anti-bacterial effects against common urinary pathogens, highlighting its potential application in treating infections, particularly in diabetic patients.
3) Kottai:
Kottai is a term referring to 'seeds,' particularly in the context of Naaval Kottai Mathirai. This Siddha preparation uses the seeds of Syzygium cumini, which are known for their medicinal properties, including anti-diabetic and anti-bacterial effects.
4) Drug:
The term drug refers to a substance used in the diagnosis, treatment, or prevention of diseases. In this text, Naaval Kottai Mathirai is described as a Siddha drug with both anti-diabetic and anti-bacterial properties, making it useful for managing diabetes and its associated urinary tract infections.
5) Syzygium cumini:
Syzygium cumini is a plant species whose seeds are used in Naaval Kottai Mathirai, a Siddha herbal preparation. These seeds have anti-diabetic properties and contribute to the drug's effectiveness in treating urinary tract infections.
6) Chennai:
Chennai is a city in South India where the research on the Siddha preparation Naaval Kottai Mathirai was conducted. The authors of the study are affiliated with various institutions based in Chennai, including the National Institute of Siddha.
7) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing diseases. The Siddha system of medicine, to which Naaval Kottai Mathirai belongs, incorporates traditional practices and natural formulations for managing conditions like diabetes and urinary tract infections.
8) Aureus:
Aureus is part of the name of the bacterium Staphylococcus aureus, which is one of the urinary pathogens tested against Naaval Kottai Mathirai. The study found that the Siddha drug exhibited significant anti-bacterial activity against this pathogen.
9) Bitter:
Bitter is one of the six tastes in Siddha medicine that helps destroy microorganisms, reduce blood sugar levels, and eliminate toxins from the body. One of the ingredients in Naaval Kottai Mathirai, Aristolochia bracteolata, has a bitter taste, contributing to the formulation's effectiveness in treating infections.
10) Blood:
Blood refers to the fluid circulating in the body's vascular system. In Siddha medicine, certain tastes like astringent and bitter are believed to purify the blood and heal wounds. Naaval Kottai Mathirai, containing ingredients with these tastes, is used to manage blood sugar levels and treat infections in diabetic patients.
11) Discussion:
The discussion section interprets the results of scientific studies. In this text, it elaborates on the effectiveness of Naaval Kottai Mathirai in treating urinary tract infections in diabetic patients, supporting its dual role in managing both diabetes and infections.
12) Tamilnadu (Tamil-nadu):
Tamilnadu is a state in South India where the ingredients for Naaval Kottai Mathirai were collected. The research discussed in the text is also rooted in this region, reflecting the deep connection between Siddha medicine and Tamil culture.
13) Village:
Village refers to the rural area where the plant materials for Naaval Kottai Mathirai were sourced. In this case, the Seeganendal village in Pudukkottai district, Tamilnadu, served as the source for collecting Syzygium cumini seeds and Aristolochia bracteolata leaves.
14) Mineral:
Mineral pertains to the inorganic substances used in some Siddha formulations. While Naaval Kottai Mathirai mainly uses plant-based ingredients, many Siddha medicines incorporate minerals, metals, and herbs for their therapeutic effects.
15) India:
India is the country where the Siddha system of medicine originated and where the study on Naaval Kottai Mathirai was conducted. Institutions like the National Institute of Siddha in Chennai play a crucial role in preserving and advancing this traditional medical system.
16) Ayus (Ayush):
AYUSH stands for Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy. It is an acronym used in India to represent the country's traditional systems of medicine, including the Siddha system, under which Naaval Kottai Mathirai was studied for its anti-diabetic and anti-bacterial effects.
17) Sugar:
Sugar refers to glucose levels in the blood, an important factor in diabetes management. Naaval Kottai Mathirai contains ingredients that help reduce blood sugar levels, addressing one of the key issues in diabetic patients.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Anti-bacterial effect of Naaval Kottai Mathirai on urinary pathogens’. Further sources in the context of Science might help you critically compare this page with similair documents:
Diabetes mellitus, Polyherbal formulation, Antimicrobial effect, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Urinary tract infection, Enterococcus faecalis, Glycosuria, Klebsiella pneumonia, Bacillus subtilis, Bacteriuria, Resistant pathogens, Anti-bacterial effect, Siddha preparation, Neutrophil dysfunction.