Study on Sharkara Mishrita Dugda Nasya vs Murchita Ghrita Nasya for Migraine

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Journal name: Ayushdhara
Original article title: A comparative clinical study on sharkara mishrita dugda nasya and murchita ghrita nasya on ardhavabhedaka w.s.r. to migraine
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Author(s):

*Santosh S. Pujari
PG Final year Scholar, PG Department of Shalakya Tantra, SVM Ayurvedic Medical College, Ilkal, Karnataka
Veerayya Hiremath
Professor & Head, PG Department of Shalakya Tantra, SVM Ayurvedic Medical College, Ilkal, Karnataka


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: A comparative clinical study on sharkara mishrita dugda nasya and murchita ghrita nasya on ardhavabhedaka w.s.r. to migraine

Year: 2017

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Introduction

Ardhavabhedaka, recognized as one of the 11 types of Shirorogas in Ayurvedic texts, is characterized by unilateral headache frequently correlated with migraine in both etiology and treatment. The aim of this clinical study was to compare the effects of two nasya treatments—Sharkara Mishrita Dugda Nasya and Murchita Ghrita Nasya—in managing Ardhavabhedaka. A cohort of 30 patients was divided into two groups, with each group receiving one of the nasya treatments for seven days, after which their symptoms were evaluated based on clinical parameters to determine the effectiveness of each treatment.

Effectiveness of Murchita Ghrita Nasya

The clinical trial demonstrated that Murchita Ghrita Nasya provided a significantly better therapeutic response compared to Sharkara Mishrita Dugda Nasya. Out of 15 patients in the Murchita Ghrita Nasya group, 36% exhibited a good response post-treatment, while only 16% of the Sharkara Mishrita Dugda Najya group showed similar results. The study highlighted that Murchita Ghrita acted effectively as a Tridoshaghna treatment, effectively addressing the imbalance of doshas that contribute to Ardhavabhedaka, thus reducing the severity of symptoms more effectively.

Insights on Ardhavabhedaka

Findings from the study reveal that Ardhavabhedaka is predominantly seen in young adults aged 21-30 years, with a higher incidence in males. Factors such as excessive work, improper dietary habits, and lifestyle choices are significant contributors to this condition. The analysis identified specific risk factors, including the consumption of certain triggers like chocolate, cheese, and nuts, emphasizing the need for dietary adjustments as part of the overall treatment and prevention strategy for migraine-like headaches in this population.

Conclusion

The study concludes that both nasya treatments have beneficial effects, but Murchita Ghrita Nasya proves to be the more effective therapeutic option for managing Ardhavabhedaka. Additionally, identifying and avoiding aggravating factors is crucial in controlling headaches and preventing episodes. Integrating lifestyle modifications along with targeted Ayurvedic treatments can aid in managing this condition more effectively, promoting overall well-being in patients suffering from Ardhavabhedaka.

FAQ section (important questions/answers):

What is the study comparing in the treatment of migraine?

The study compares the effects of 'Sharkara Mishrita Dugda Nasya' and 'Murchita Ghrita Nasya' on managing 'Ardhavabhedaka,' a type of headache similar to migraine.

What were the main findings regarding treatments for Ardhavabhedaka?

Both treatments showed improvement in symptoms, but 'Murchita Ghrita Nasya' had a better overall response, effectively reducing headache severity in patients.

What demographic was most affected by Ardhavabhedaka in the study?

The study found that individuals aged 21-30 years, particularly males, were most commonly affected by Ardhavabhedaka, with contributing factors such as stress and dietary habits.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Study on Sharkara Mishrita Dugda Nasya vs Murchita Ghrita Nasya for Migraine”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Nasya (Nashya):
Nasya is a form of Ayurvedic treatment where medicated oils or powders are administered through the nostrils. This treatment is commonly used for curing diseases related to the head, including Ardhavabhedaka.[see source text or glossary: Nasya]

2) Ardhavabhedaka:
Ardhavabhedaka is one of the 11 types of Shirorogas (diseases of the head) in Ayurveda. It is defined by pain localized to one half of the head and is analogous to migraine in modern medicine. Its management often includes Nasya therapeutics.[see source text or glossary: Ardhavabhedaka]

3) Sharkara (Sarkara):
Sharkara is a keyword referring to sugar. In the context of this study, Sharkara is mixed with Dugdha (milk) for Nasya treatment to alleviate Ardhavabhedaka symptoms.[see source text or glossary: Sharkara]

4) Ghrita (Ghrta):
Ghrita refers to clarified butter or ghee. In this study, Murchita Ghrita (processed ghee) is used in Nasya treatment for Ardhavabhedaka and found effective due to its Tridoshaghna properties.[see source text or glossary: Ghrita]

5) Drug:
Drug in this context refers to the medicinal substances used in the Ayurvedic treatment, specifically for Nasya which includes Sharkara Mishrita Dugdha and Murchita Ghrita.[see source text or glossary: Drug]

6) Disease:
Disease refers to a pathological condition affecting the body. In this study, Ardhavabhedaka is the disease under investigation, which is similar to migraine in modern medicine.[see source text or glossary: Disease]

7) Vata:
Vata is one of the three Doshas in Ayurveda. It plays a critical role in bodily functions and is predominantly involved in Ardhavabhedaka (migraine).[see source text or glossary: Vata]

8) Pain:
Pain, in this study, specifically pertains to headache in one half of the head, characteristic of Ardhavabhedaka, measured through subjective criteria like Samvedana (pain perception).[see source text or glossary: Pain]

9) Prakasha (Prakasa):
Prakasha Asahisnatha denotes light intolerance or photosensitivity. It is a symptom considered during the assessment of Ardhavabhedaka patients.[see source text or glossary: Prakasha]

10) Shiroroga (Siroroga, Shiras-roga):
Shiroroga refers to diseases affecting the head. Ardhavabhedaka, a type of Shiroroga, involves intense headache focused on one side of the head.[see source text or glossary: Shiroroga]

11) Dugdha:
Dugdha means milk. In this study, Dugdha is used alongside Sharkara for Nasya treatment to address Ardhavabhedaka symptoms.[see source text or glossary: Dugdha]

12) Bhrama:
Bhrama refers to dizziness or vertigo. It is one of the symptoms evaluated in the clinical study for Ardhavabhedaka.[see source text or glossary: Bhrama]

13) Uttamanga (Uttama-anga, Uttamamga):
Uttamanga Ardhabhaga Sambhedha indicates pain in one half of the head, a primary diagnostic criterion for Ardhavabhedaka.[see source text or glossary: Uttamanga]

14) Nasyakarman (Nasyakarma, Nasya-karma):
Nasya-karma is the procedure of administrating medicated oils or powders through nostrils for therapeutic purposes, particularly useful in treating Shirorogas like Ardhavabhedaka.[see source text or glossary: Nasya-karma]

15) Samtosha (Samtosa, Santosa, Santosha, Santosh):
Santosh S. Pujari is a researcher involved in the study comparing Sharkara Mishrita Dugda Nasya and Murchita Ghrita Nasya in treating Ardhavabhedaka.[see source text or glossary: Santosh]

16) Pujari:
Santosh S. Pujari is the PG Final year Scholar responsible for conducting the clinical study on Nasya treatments for Ardhavabhedaka.[see source text or glossary: Pujari]

17) Shiras (Siras, Siro, Shirash):
Shiro refers to the head in Ayurveda, underscoring the focus area for diseases like Ardhavabhedaka and their treatments.[see source text or glossary: Shiro]

18) Dosha (Dosa):
Dosha refers to the three fundamental bodily humors in Ayurveda: Vata, Pitta, and Kapha. Vata is predominantly implicated in Ardhavabhedaka.[see source text or glossary: Dosha]

19) Karma (Karman):
Karma in this context denotes the procedural aspect of treatments, such as Nasya karma, which involves specific methods for managing diseases like Ardhavabhedaka.[see source text or glossary: Karma]

20) Sira (Shira):
Sira refers to blood vessels or channels in the body, which are believed to be involved in the process by which Nasya drugs reach their target areas in the head.[see source text or glossary: Sira]

21) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha is one of the three Doshas and is responsible for all bodily activities, whether physiological or pathological. It plays a significant role in Ardhavabhedaka and is the primary focus of treatment.[see source text or glossary: Vata-dosha]

22) Vataja (Vata-ja):
Vataja refers to conditions predominantly caused by Vata-dosha. According to some Ayurvedic texts, Ardhavabhedaka can be Vataja in nature.[see source text or glossary: Vataja]

23) Shalakyatantra (Salakyatantra, Shalakya-tantra, Shalakyatamtra):
Shalakya-tantra is a branch of Ayurveda focusing on the treatment of diseases above the clavicle, including Shiro-roga like Ardhavabhedaka.[see source text or glossary: Shalakya-tantra]

24) Vatapittahara (Vatapitta-hara):
Vatapittahara denotes those substances that alleviate Vata and Pitta doshas. Sharkara is identified as having Vatapittahara properties, useful in treating Ardhavabhedaka.[see source text or glossary: Vatapittahara]

25) Karnataka:
Karnataka is the state in India where the study was conducted at SVM Ayurvedic Medical College, emphasizing local relevance to the Ayurvedic practices described.[see source text or glossary: Karnataka]

26) Vagbhata:
Vagbhata is an ancient Ayurvedic scholar who opines that Ardhvabheadaka involves Vata dosha and discussed it in relation to other head diseases in Ayurvedic texts.[see source text or glossary: Vagbhata]

27) Medicine:
Medicine in this context refers to the Ayurvedic preparations (Sharkara Mishrita Dugdha, Murchita Ghrita) used for Nasya in managing Ardhavabhedaka.[see source text or glossary: Medicine]

28) Nostril:
Nostril is the route of administration for Nasya therapies, where medicated oils or powders are introduced for treating head-related ailments like Ardhavabhedaka.[see source text or glossary: Nostril]

29) Tantra (Tamtra, Tantrism):
Tantra in Ayurveda refers to various branches or fields of study. Shalakya-tantra deals specifically with diseases of the head and sense organs.[see source text or glossary: Tantra]

30) Nidana:
Nidana refers to the causes or triggers of diseases. Avoiding factors like Vegadharana and Adhyasana is critical in managing Ardhavabhedaka.[see source text or glossary: Nidana]

31) Marma:
Marma refers to vital points in the body. The Sringataka Marma is involved in the mechanism of Nasya treatment for Ardhavabhedaka.[see source text or glossary: Marma]

32) India:
India is the country where the study was conducted, highlighting the Ayurvedic approach rooted in Indian traditional medicine.[see source text or glossary: India]

33) Food:
Food habits, such as consumption of tea, coffee, and chocolates, are examined as potential triggers for Ardhavabhedaka in the study.[see source text or glossary: Food]

34) Ashtangasamgraha (Astangasamgraha, Astangasangraha, Ashtanga-samgraha, Ashtanga-sangraha, Ashtangasangraha):
Astanga Sangraha is an Ayurvedic text where the concept of Sringataka and the mechanism of Nasya are explained, relevant to the treatment of Ardhavabhedaka.[see source text or glossary: Astanga-sangraha]

35) Madhavanidana (Madhava-nidana):
Madhava Nidana is an Ayurvedic text that describes disease diagnostics, including Ardhavabhedaka, informing clinical assessments in the study.[see source text or glossary: Madhava-nidana]

36) Tuberculosis:
Tuberculosis is listed as one of the exclusions in the study, ensuring that patients with such systemic disorders are not part of the clinical trial for Ardhavabhedaka treatments.[see source text or glossary: Tuberculosis]

37) Urdhvajatru (Urdhva-jatru):
Urdhvajatru refers to the region above the clavicle. Ardhavabhedaka is a disease affecting this area, specifically the Shiras (head).[see source text or glossary: Urdhvajatru]

38) Adhyashana (Adhyasana):
Adhyasana, like Adhyashana, refers to excessive eating, listed among the potential triggers for Ardhavabhedaka, illustrating the need to manage diet in the disease.[see source text or glossary: Adhyasana]

39) Tridoshaja (Tridosaja):
Tridoshaja indicates that a disease involves all three Doshas: Vata, Pitta, and Kapha. Ardhavabhedaka is sometimes considered Tridoshaja with a predominance of Vata-dosha.[see source text or glossary: Tridoshaja]

40) Arunadatta:
Arunadatta contributed commentary to classic Ayurvedic texts, explaining the mechanism of Nasya treatment which is used for Ardhavabhedaka.[see source text or glossary: Arunadatta]

41) Discussion:
Discussion in the study evaluates the clinical efficacy and observations of Nasya treatments for Ardhavabhedaka, comparing Sharkara Mishrita Dugdha Nasya and Murchita Ghrita Nasya.[see source text or glossary: Discussion]

42) Irritation:
Irritation refers to stimulation that could occur due to the Nasya treatment, potentially affecting nerve terminals and alleviating symptoms of Ardhavabhedaka.[see source text or glossary: Irritation]

43) Samvadana (Samvedana):
Samvedana refers to the perception of pain, such as in Uttamanga Ardhabhaga Samvedana, a key symptom assessed in Ardhavabhedaka patients.[see source text or glossary: Samvedana]

44) Blindness:
Blindness is mentioned as a severe outcome if Ardhavabhedaka is left untreated, highlighting the importance of early intervention with treatments like Nasya.[see source text or glossary: Blindness]

45) Ayurveda (Ayus-veda):
Ayurveda, the traditional Indian system of medicine, forms the basis of the study's approach to treating Ardhavabhedaka, using therapies like Nasya.[see source text or glossary: Ayurveda]

46) Tridosha (Tridosa, Tri-dosha):
refers to the three fundamental energies (Vata, Pitta, Kapha) in Ayurveda. Ardhavabhedaka can involve Tridosha imbalance, and the treatments aim to balance these doshas.[see source text or glossary: Tridosha]

47) Abhyanga (Abhyamga):
Abhyanga is a preparatory procedure of local massage with oil before administering Nasya, improving the effectiveness of the treatment for Ardhavabhedaka.[see source text or glossary: Abhyanga]

48) Pradesha (Pradesa):
Pradesha refers to a region or area of the body. Pain in specific pradeshass, like Karna Pradesha, is noted in Ardhavabhedaka.[see source text or glossary: Pradesha]

49) Deafness:
Deafness is a serious complication that can arise from untreated Ardhavabhedaka, emphasizing the need for prompt and effective treatment.[see source text or glossary: Deafness]

50) Samgraha (Sangraha):
Sangraha or Astanga Sangraha is an important Ayurvedic text, providing foundational knowledge for treatments including Nasya for Ardhavabhedaka.[see source text or glossary: Sangraha]

51) Samhita:
Samhita refers to Ayurvedic compendiums like Bhela Samhita and Charaka Samhita, which describe diseases like Ardhavabhedaka and their treatments.[see source text or glossary: Samhita]

52) Kaphaja:
Kaphaja refers to conditions caused by Kapha dosha. Ardhavabhedaka can sometimes be Kaphaja or a mix of Vata and Kapha doshas.[see source text or glossary: Kaphaja]

53) Vriddha (Vrddha):
Vriddha Vagbhata is an Ayurvedic scholar who explained the action of Nasya, relevant to understanding its efficacy in treating Ardhavabhedaka.[see source text or glossary: Vriddha]

54) Madhava:
Madhava Nidana by Madhava is a classic Ayurvedic text used for diagnosing conditions like Ardhavabhedaka, referenced in the study.[see source text or glossary: Madhava]

55) Ashtanga (Astanga, Ashtan-anga):
Astanga Sangraha is an Ayurvedic text that provides insights into treatments like Nasya for Ardhavabhedaka, offering theoretical backing for clinical practices.[see source text or glossary: Astanga]

56) Sevana:
Sevana refers to the consumption of certain substances such as Purva Vata Sevana, which can trigger Ardhavabhedaka. Managing these triggers is crucial for treatment.[see source text or glossary: Sevana]

57) Shanka (Sanka, Samka):
Shanka refers to the temporal region of the head. Pain in this area is characteristic of Ardhavabhedaka, assessed in the clinical study.[see source text or glossary: Shanka]

58) Lalata:
Lalata refers to the forehead. Pain in this region is a symptom of Ardhavabhedaka, monitored during the clinical assessments.[see source text or glossary: Lalata]

59) Videha:
Videha, in the context of Nimitantra authors, describes Ardhavabhedaka as involving Vata and Kapha doshas, aiding in the understanding of its pathophysiology.[see source text or glossary: Videha]

60) Nature:
Nature of Ardhavabhedaka involves recurring headache episodes, often correlating with migraine, characterized by its specific location and symptoms in classical Ayurvedic texts.[see source text or glossary: Nature]

61) Murdha (Murdhan):
Murdha refers to the head. Nasya treatments target the Murdha to alleviate symptoms of head-related diseases like Ardhavabhedaka.[see source text or glossary: Murdha]

62) Bhava:
Bhava Prakasha is an Ayurvedic text that discusses various diseases including Ardhavabhedaka, providing guidelines for its diagnosis and treatment.[see source text or glossary: Bhava]

63) Karna:
Karna refers to the ear. Pain extending to the ear is one of the diagnostic criteria for Ardhavabhedaka, relevant in clinical assessments.[see source text or glossary: Karna]

64) Purva:
Purva Vata Sevana refers to excessive indulgence or strain, listed as one of the triggers or causes of Ardhavabhedaka in Ayurvedic texts.[see source text or glossary: Purva]

65) Ayus (Ayush):
Ayush pertains to the traditional Indian systems of medicine, under which this study on Nasya treatments for Ardhavabhedaka is conducted.[see source text or glossary: Ayush]

66) Blood:
Blood vessels (Siras) are pathways where the medicated Nasya drugs travel to reach target areas in Ardhavabhedaka management, as described in the study.[see source text or glossary: Blood]

67) Indu (Imdu):
Indu, a commentator on Astanga Sangraha, elaborates on the Sringataka, relevant to understanding Nasya's action in treating Ardhavabhedaka.[see source text or glossary: Indu]

68) Diet:
Diet, including specific foods like chocolate and nuts, is identified as a trigger for Ardhavabhedaka, highlighting the role of dietary management in treatment.[see source text or glossary: Diet]

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Ayurveda, Toda, Bhrama, Ardhavabhedaka, Nasyakarman, Age-group, Inclusion criteria, Exclusion criteria, Nidana Parivarjana, Migraine headache, Clinical parameter.

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