Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content

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Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.

Original source:

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Author(s):

Swarnendu Mitra
V. J. Shukla
Rabinarayan Acharya


AYU (Journal of Research in Ayurveda):

(An International Quarterly Journal of Research in Ayurveda)

Full text available for: Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content

Year: 2011 | Doi: 10.4103/0974-8520.93923

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Kupeelu (Strychnos nux-vomica Linn.) commonly known as nux vomica is a poisonous plant used extensively in various ayurvedic formulations, with great therapeutic significance. Ayurveda recommended the administration of Kupeelu only after purification in different media like cow's urine (Go mutra), cow's milk (Go dugdha), cow's ghee (Go ghrita), Kanji (sour gruel), and so on. Apart from the classical methods some other methods are also adopted by the traditional practitioners using castor oil (Eranda taila), ginger juice (Ardraka swarasa), in the purification of Kupeelu seeds. In the present study an attempt has been made to purify the seeds by performing two different methods (one classical and another traditional) using Kanji and Ardraka swarasa as Shodhana media. This study reveals that both the methods studied reduce the strychnine and brucine contents in comparison to the raw seeds as determined by high performance thin layer chromatography (HPTLC). After purification in Kanji and Ardraka swarasa, the strychnine content was reduced by 39.25% and 67.82%, respectively, and the brucine content in the purified seeds was also found to have decreased by 17.60% and 40.06%, in comparison to the raw seeds. Keywords: Ardraka swarasa, brucine, kanji, kupeelu, shodhana, strychnine

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Discover the significance of concepts within the article: ‘Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content’. Further sources in the context of Science might help you critically compare this page with similair documents:

Kanji, Nux-vomica, Castor oil, Sour gruel, Cow urine, Cow milk, Purification method, Ginger juice, Shodhana purification, Cow's ghee, Detoxification process, Ayurvedic formulation, High performance thin layer chromatography, Anti-inflammatory activities, Hepatoprotective activities, Analgesic and anti-inflammatory, Moisture content, Ardraka swarasa, Strychnine and brucine, High performance thin layer chromatography (HPTLC), Antioxidant, Analgesic activities, Anti-oxidant activities, Anti-tumor activities, Anti-snake venom, Anti-diarrheal activities, Kanji preparation, HPTLC technique, Extractive value, Toxic alkaloid, Traditional Practitioner.

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