Evaluation of antioxidant capacity of polyherbal drug Bhāraṅgyādi.
Journal name: Ancient Science of Life
Original article title: Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug- Bhāraṅgyādi
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Divya Kumari Kajaria, Mayank Gangwar, Amit Kumar Sharma, Yamini Bhusan Tripathi, Jyoti Shankar Tripathi, Shrikant Tiwari
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug- Bhāraṅgyādi
Year: 2012
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
The study focused on the antioxidant activity of a polyherbal formulation known as Bhāraṅgyādi, composed of three Ayurvedic herbs: Clerodendrum serratum, Hedychium spicatum, and Inula racemosa. With increasing concerns regarding the adverse effects of synthetic antioxidants, the need for safe and economical natural alternatives is paramount. Free radicals, which can lead to various diseases, including cancer and heart disease, are generated in the body through different processes. The presence of antioxidants, particularly from natural sources, plays a crucial role in mitigating the damage caused by these free radicals.
Antioxidant Potentials of Bhāraṅgyādi
The study employed various in vitro assays to evaluate the antioxidant capacities of the Bhāraṅgyādi extract. The results demonstrated a dose-dependent increase in antioxidant activity as the concentration of the extract increased. Specific assays, including the ABTS+ scavenging assay and superoxide anion scavenging activity, indicated significant inhibition rates, with maximum benefits observed at higher concentrations. The Bhāraṅgyādi extract showcased a substantial reducing power, as evidenced by its ability to convert Fe3+ to Fe2+, paralleling the standard antioxidant quercetin. The results suggest that the polyherbal formulation holds considerable promise as a source of natural antioxidants, primarily attributable to its phenolic and flavonoid content.
Conclusion
In conclusion, the findings affirm that the polyherbal formulation Bhāraṅgyādi possesses significant antioxidant activity, making it a noteworthy candidate for natural therapeutic approaches against oxidative stress. The study highlights the need for further research to isolate and characterize the active compounds responsible for the observed biological activity. Given the correlation between the antioxidant capabilities and the total polyphenolic content, Bhāraṅgyādi could be further explored to develop effective treatments for various conditions associated with oxidative damage. The results advocate for a shift towards utilizing natural antioxidants in healthcare to avoid potential side effects associated with synthetic alternatives.
FAQ section (important questions/answers):
What was the purpose of the study on Bhāraṅgyādi?
The study aimed to investigate the antioxidant activity of the polyherbal formulation Bhāraṅgyādi, which includes Clerodendrum serratum, Hedychium spicatum, and Inula racemosa, to find new, safe, and inexpensive antioxidants.
Which methods were used to test antioxidant activity?
The study employed various assays, including ABTS+ assay, superoxide anion scavenging activity assay, and lipid peroxidation assay, to assess the total reducing power and antioxidant capacity of Bhāraṅgyādi extracts.
What were the key findings regarding the antioxidant activity?
The Bhāraṅgyādi extracts demonstrated significant antioxidant potential, with maximum inhibition values of 64.2% in ABTS+ assays and effective scavenging of superoxide and lipid peroxidation, suggesting a good source of natural antioxidants.
What is the significance of polyphenols in the study?
Polyphenols, present in the polyherbal formulation, were found to correlate strongly with antioxidant activity, highlighting their importance in scavenging free radicals and promoting health benefits.
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘Evaluation of antioxidant capacity of polyherbal drug Bharangyadi.’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
Hedychium spicatum, Inula racemosa, Polyherbal formulation, Oxidative stress, Lipid peroxidation, Biological Activity, Antioxidant capacity, Clerodendrum Serratum, Total antioxidant activity, Hydroalcoholic extract, Superoxide radical, Free Radical, Tissue damage, Natural antioxidant, Reducing potential, Creative Commons Attribution, Phenol and flavonoid content.