Metal Complexes of Glabrin from Pongamia glabra Linn. Seeds
Journal name: Ancient Science of Life
Original article title: Preparation and Estimation of Metal Complexes of Glabrin from Pongamia glabra Linn. Seeds
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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H.S. Chandel, Akhilesh Singhai, S Nayak
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Preparation and Estimation of Metal Complexes of Glabrin from Pongamia glabra Linn. Seeds
Year: 2005
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
The study focuses on the preparation and estimation of metal complexes of glabrin, a compound isolated from the seeds of Pongamia glabra Linn., also known as Karanja. The research describes the processes of metal complex preparation involving metals such as copper, zinc, and mercury via refluxing with their respective acetates. The estimation of metal content in the resulting complexes was achieved using iodometric and E.D.T.A. methods, yielding significant information regarding the composition and potential applications of these metal complexes.
Importance of Metal Complexes of Glabrin
The formation of metal complexes with glabrin showcases potential pharmacological significance, as these complexes exhibit antimicrobial activity. The study confirmed the structure of glabrin and its metal complexes through negative tests for α-amino acids and comparative analysis of theoretical and calculated metal percentages. The results demonstrated close alignment between experimental findings and expected values, reinforcing the reliability of the preparation and estimation methods employed. This opens avenues for further exploration of glabrin's metal complexes in pharmacology, potentially leading to the development of new therapeutic agents.
Conclusion
The successful isolation of glabrin and the preparation of its metal complexes highlight the efficacy of simple and precise methodologies in the study of phytochemicals. Estimations affirmed the metal content in complexes aligned well with theoretical calculations, suggesting accurate experimental techniques. The findings encourage further research into the pharmacological activities of glabrin and its complexes, underscoring its potential for medicinal application and the value of natural products in developing new treatments.
FAQ section (important questions/answers):
What is glabrin and where is it derived from?
Glabrin is a compound isolated from the seeds of Pongamia glabra. It has applications in traditional medicine and potential pharmaceutical benefits due to its bioactive properties.
How were metal complexes of glabrin prepared in the study?
Metal complexes of glabrin were prepared by refluxing glabrin with acetates of copper, zinc, and mercury in a 1:2 ratio. This process was aimed at enhancing the properties of glabrin through complexation.
What methods were used to estimate metals in the complexes?
Copper was estimated using the iodometric method, while zinc and mercury were estimated using the EDTA method. These methods provided a straightforward means to quantify metal content in the complexes.
What are the potential pharmacological activities of glabrin and its complexes?
Glabrin and its metal complexes exhibit significant antimicrobial activity, suggesting potential therapeutic applications. Further research may uncover additional pharmacological effects that could expand their use in medicine.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Metal Complexes of Glabrin from Pongamia glabra Linn. Seeds”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Water:
Water is a crucial solvent in many chemical processes, including the extraction and preparation of glabrin metal complexes from Pongamia glabra seeds. It facilitates the dissolution of compounds and their reactions, showcasing its significance in laboratory methods and in the overall yield of the desired results in scientific studies.
2) Pharmacological:
Pharmacological relates to the branch of medicine that focuses on the study of drug action. In this context, the pharmacological properties of glabrin and its metal complexes suggest potential healing capabilities. The findings imply opportunities for new drug development, enhancing the understanding of herbal remedies and their therapeutic applications.
3) Discussion:
The discussion section evaluates and interprets the results obtained from the experiments. It is essential for contextualizing findings, highlighting their significance in the research landscape, and providing insights into potential future research avenues, particularly regarding the medicinal applications of metal complexes derived from glabrin.
4) Substance:
Substance refers to a specific physical matter or compound, in this case, glabrin isolated from Pongamia glabra seeds. Understanding the chemical and physical characteristics of the substance is vital to assess its properties, such as solubility and interactions, which are critical for preparing and studying its metal complexes.
5) Activity:
Activity, particularly referring to the biological or pharmacological activity of glabrin and its complexes, denotes the capacity to elicit physiological effects. This research investigated antimicrobial activity, which reveals potential medical applications and underscores the importance of exploring natural compounds for developing therapeutic agents.
6) Karanja (Karañja, Kārañjā, Karamja):
Karanja is the common name for Pongamia glabra, a plant known for its medicinal properties. This association highlights Karanja's relevance in traditional medicine, emphasizing its role in providing various health benefits and the importance of studying its constituents for pharmaceutical applications, as demonstrated by the analysis of glabrin.
7) Science (Scientific):
Science encompasses the systematic study of the structure and behavior of the physical and natural world. In this context, the research relates to the scientific exploration of herbal extracts, chemical analyses, and the preparation of metal complexes, underscoring the importance of scientific methodology in discovering new therapeutic agents.
8) Botany:
Botany is the scientific study of plants, including their physiology, structure, and uses. The identification of Pongamia glabra seeds, confirmed by the Department of Botany, emphasizes the importance of botanical research in the exploration of plant-based resources that have potential pharmacological applications, supporting the development of natural medicines.
9) Hari (Hāri, Hārin, Harī, Harin):
Hari refers to Dr. Hari Singh Gour Vishwavidyalaya, a key institution in the academic confirmation of plant identification. This highlights the role of educational institutions in research, ensuring the authenticity of plant materials used in scientific studies, which is crucial for validating results and fostering reliable findings.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Metal Complexes of Glabrin from Pongamia glabra Linn. Seeds’. Further sources in the context of Science might help you critically compare this page with similair documents:
Pongamia glabra, Molecular weight, Anti-microbial activity, Ancient Science of life, Melting point determination, Co-TLC, Folk remedies, Phytoconstituents Isolated, Defatted methanolic extract, Iodometric method, Chemical assay.