Some less known central nervous system depressant

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Journal name: Ancient Science of Life
Original article title: Some less known central nervous system depressant
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:

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Author:

T. Tamizhmani, Pulok K. Mukherjee, S. Manimaran, T. Subburaj, B. Suresh


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Some less known central nervous system depressant

Year: 2003

Copyright (license): CC BY-NC-SA


Download the PDF file of the original publication


Summary of article contents:

Introduction

The study highlights the importance of medicinal plants utilized as sedative agents within traditional systems of medicine, specifically focusing on Siddha and Ayurveda. It emphasizes that throughout history, humans have sought comfort and altered states of mind through various substances, and a significant percentage of prescriptions in modern medicine aim to modify mental processes. The paper examines the efficacy of sedatives, underlining the necessity for a calming effect with minimal impact on motor and mental functions. This survey considers less-known Central Nervous System (CNS) depressants derived from ancient medicinal practices, aiming to bridge the gap between traditional and modern medicine.

The Role of Traditional Medicinal Plants

One of the critical aspects discussed is the diversity of plants used as CNS depressants, such as Valeriana wallichii (Jatamansi), which is known for its sedative properties due to the presence of valepotriates and valeranone. This plant, among others listed, has been utilized in traditional practices to aid sleep and reduce anxiety. Additionally, the study catalogs numerous plants, including Withania somnifera (Ashwagandha) and Cannabis sativa, detailing their chemical constituents and traditional applications. The enumeration of these plants, along with their local names and parts used, underscores the wealth of knowledge embedded in ancient practices that require further validation through modern scientific methods.

Conclusion

The authors express their intent to present the therapeutic value of these traditional herbal remedies to modern medicine, which often overlooks their potential due to a lack of scientific validation. By documenting and analyzing these less-known CNS depressants, the study aims to encourage further research into their efficacy and applications. Ultimately, the recognition and acceptance of these natural remedies could enhance contemporary therapeutic practices, providing a more holistic approach to mental health and wellness.

FAQ section (important questions/answers):

What are the main uses of the plants listed in the document?

The plants mentioned in the document are traditionally used as central nervous system sedatives, aimed at reducing anxiety and promoting relaxation. They are integral to Siddha and Ayurveda systems of medicine, known for their calming effects.

How were the medicinal plants in this study identified?

The medicinal plants were identified through an intensive survey of ancient literature and transcripts from the Siddha and Ayurveda systems, focusing on their lesser-known uses as CNS depressants.

Why are traditional herbal medicines not widely accepted in modern medicine?

Traditional herbal medicines often lack the scientific validation and rigorous testing required by modern medicine to establish their therapeutic value, which hinders their acceptance despite their historical use.

What types of chemical constituents are found in these plants?

The chemical constituents found in these plants include alkaloids, saponins, tannins, and volatile oils, which are attributed to their therapeutic effects as central nervous system sedatives.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Some less known central nervous system depressant”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing diseases and conditions. In the context of the text, it encompasses traditional methods such as Siddha and Ayurveda, which utilize herbal remedies to manage health, especially nerves and mental states, highlighting the ancient reliance on natural substances for healing.

2) Drug:
A drug is a substance used to diagnose, treat, or prevent diseases or to enhance physical or mental well-being. The article discusses various herbal drugs that functions as sedatives, showcasing how these natural compounds impact the Central Nervous System and contribute to emotional and psychological health.

3) Siddha (Siddhā):
Siddha is a traditional system of medicine that originated in South India. It emphasizes the use of herbal formulations and holistic healing practices, often integrating spiritual aspects into treatment. The text highlights the importance of Siddha in identifying herbal sedatives and their relevance in contemporary therapeutic practices.

4) Brahmi (Brāhmī):
Brahmi, scientifically known as Bacopa monnieri, is a prominent herb in Ayurvedic medicine recognized for its cognitive-enhancing properties and calming effects on the mind. Its inclusion in the list of medicinal plants emphasizes the traditional belief in its effectiveness against anxiety and promoting mental clarity.

5) Science (Scientific):
Science is the pursuit of knowledge and understanding of the natural and social world through systematic experimentation and observation. In the article, the scientific method plays a crucial role in validating the therapeutic claims of traditional medicinal herbs, striving to integrate ancient wisdom with modern healthcare.

6) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes balance in bodily systems using diet, herbal treatment, and yogic breathing. The article reviews Ayurvedic herbs employed as sedatives, illustrating the rich heritage and therapeutic potential of these natural remedies in contemporary health practices.

7) Valeriana wallichii:
Valeriana wallichii, commonly known as Jatamansi, is a medicinal herb used in various traditional systems for its sedative and calming properties. Its inclusion in the enumeration correlates with its historical significance in treating nervous disorders and promoting better sleep, emphasizing traditional knowledge in herbal pharmacology.

8) Withania somnifera:
Withania somnifera, also known as Ashwagandha, is a potent adaptogen used in Ayurvedic medicine to alleviate stress and enhance mental clarity. Its mention reflects the emphasis on natural remedies for anxiety and mood regulation, showcasing its utility within the framework of traditional medicinal systems.

9) Tutturabenda (Tutturabendā, Tuttura-benda):
Tuttura-benda, or Abutilon indicum, is recognized in traditional medicine for its therapeutic benefits, including potential sedative effects. The local and scientific nomenclature highlights its role in cultural practices of healing, reinforcing the significance of indigenous plants in the pursuit of health and well-being.

10) Citrus medica:
Citrus medica, known as Citrus medica in Latin, has medicinal properties attributed to its essential oils and components like limonene. Its inclusion in the document reflects the significance of citrus fruits in traditional medicine systems for psychological and emotional well-being, demonstrating their widespread usage.

11) Discussion:
Discussion refers to the part of the document where authors reflect on findings, implications, and the broader significance of their research. It serves as a platform to draw connections between traditional practices and potential scientific validations, fostering dialogue about the integration of herbal medicine into modern healthcare.

12) Depression:
Depression is a mood disorder characterized by persistent feelings of sadness and loss of interest. The article discusses various herbal agents that may assist in alleviating symptoms of depression, aligning with traditional approaches that prioritize natural remedies in managing both physical and mental health.

13) Nishpava (Niṣpāva):
Nishpava, referred to as Dilichos lab lab, is utilized in traditional medicine due to its various health benefits, particularly concerning mental well-being. Its identification emphasizes the diversity of herbs used across systems, rooting the significance of less-known plants in addressing psychological health issues.

14) Nirgundi (Nirguṇḍī, Nirgumdi):
Nirgundi, or Vitex negundo, is a medicinal plant praised for its analgesic and anti-inflammatory properties. The mention of this herb signifies the relevance of traditional alternatives in providing holistic solutions for various health challenges, particularly those affecting the nervous system and emotional well-being.

15) Bharngi (Bhārṅgī):
Bharngi, or Clerodendron serratum, is traditionally used to manage respiratory and neurological conditions. Its listing showcases the array of herbal treatments available in Siddha and Ayurveda, underlining the importance of botanical knowledge in offering therapeutic benefits in traditional medicinal practices.

16) Naranga (Nāraṅga, Narāṅga, Nara-anga, Naramga):
Naranga, or Citrus medica, holds significance in traditional medicine not just for its culinary use but also as a remedy for gastrointestinal and respiratory ailments. Its properties reflect the importance of incorporating natural elements from the environment into healing practices within Ayurveda.

17) Kandara (Kandarā, Kaṇḍarā, Kamdara):
Kandara, or Citrus medica, is highlighted in the text for its potential relaxing effects and contributions to traditional health practices. This reinforces the role of citrus fruits in traditional systems aimed at soothing the mind and enhancing emotional balance through natural sources.

18) Anxiety:
Anxiety is characterized by excessive worry and unease, often requiring holistic approaches for management. The article discusses herbal sedatives traditionally used to alleviate anxiety, underscoring the reliance on natural remedies in Siddha and Ayurveda as vital tools for emotional regulation.

19) Kapala (Kapāla, Kāpāla, Kapālā):
Kapala, referring to Ixora coccinea, is used in folk medicine for its potential health benefits. Including this plant indicates the rich tradition of using local flora for various purposes, further emphasizing the connection between cultural heritage and medicinal practices in managing health.

20) Tamara (Tāmara, Ṭamāra, Ṭamarā):
Tamara, or Nelumbium speciosum, is significant for its traditional uses in managing mental health issues. The inclusion of this plant reflects the historical reliance on aquatic herbs in traditional systems, presenting an integral part of the broader contemplation of herbal efficacy.

21) Kanka (Kaṅka, Kaṅkā, Kamka):
Kanka, referring to Abutilon indicum, suggests its roles in traditional healing practices. Its ergonomic usage signifies the wider spectrum of medicinal plants utilized for their calming effects, highlighting a continuing legacy of natural remedies for emotional and psychological health.

22) Nocci:
Nocci, known as Vitex negundo, is included as a traditional medicinal plant recognized for its various therapeutic properties. The understanding of its applications supports the broader narrative of indigenous knowledge and its preservation within contemporary healthcare paradigms.

23) Acrid:
Acrid describes a sharp or pungent taste, often associated with certain medicinal plants. In the context of herbal medicine, understanding taste profiles like acridity can guide practitioners in selecting appropriate herbs for desired therapeutic outcomes, reflecting the complexity of traditional healing systems.

24) Shala (Sālā, Sāla, Śala, Śālā, Śāla, Sala):
Sala, or Tectona grandis, is recognized for its hardwood value and medicinal properties. Including it in the discussion highlights the importance of timber in traditional healing practices, showcasing the versatile use of plants for both structural and therapeutic purposes.

25) Amla (Amlā, Āmlā):
Amla, or Phyllanthus emblica, is celebrated in traditional medicine for its numerous health benefits, including its effects on mood and vitality. Its presence reinforces the foundational role of fruit-bearing trees in Ayurvedic practices, serving as a key component in establishing holistic health paradigms.

26) Mud:
Mood refers to the emotional state of an individual, which can be influenced by various factors, including herbal remedies. The discussion of herbal sedatives in the article aligns with the understanding of mood regulation in traditional practices, emphasizing the potential of natural treatments in affecting psychological health.

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