Analgesic activity of the roots of baliospormum montanum linn
Journal name: Ancient Science of Life
Original article title: Analgesic activity of the roots of baliospormum montanum linn
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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S. Nayak, Aman Sahai, A.K. Singhai
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Analgesic activity of the roots of baliospormum montanum linn
Year: 2003
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Baliospermum montanum, commonly known as Danti or Dantimul, is a monoecious under-shrub belonging to the Euphorbiaceae family, prevalent throughout India. The plant has a reputation in traditional medicine for treating various ailments, particularly due to its roots, which are historically used for conditions such as abdominal tumors, cancer, and pain relief. The ethanolic extracts and various fractions of B. montanum have been studied for their pharmacological properties, including potential analgesic effects. This investigation specifically aimed to evaluate the analgesic activity of the roots of B. montanum through in vivo experiments in albino rats.
Analgesic Activity of B. Montanum
The study utilized a tail-flick method to assess the analgesic activity of the ethanolic extract and its chloroform fractions in albino rats, comparing these effects to the standard analgesic Diclofenac sodium. Significant findings emerged, with the ethanolic extract showing marked analgesic activity, especially at doses of 100 mg/kg and 200 mg/kg compared to a control group. Specifically, the chloroform soluble fraction demonstrated the most potent analgesic effects with activities of 256.28% and 284.24% post-administration, whereas the chloroform insoluble fraction did not yield significant activity. The observed effects suggest that the analgesic activity of B. montanum may be attributed to its diverse active compounds, such as steroids, terpenoids, and flavonoids, supporting its traditional use for pain relief.
Conclusion
In conclusion, the results of this study provide compelling evidence for the analgesic properties of Baliospermum montanum, thereby validating its folklore use in traditional medicine for pain management. The significant analgesic effects observed, particularly for the ethanolic extract and its chloroform soluble fractions, underscore the potential of indigenous plants as sources of new therapeutic agents. Further research is warranted to elucidate the mechanisms behind these effects and to support the development of analgesic drugs derived from this plant. This study highlights the importance of scientifically validating traditional remedies to expand the arsenal of pain relief options available.
FAQ section (important questions/answers):
What is the purpose of the study on Baliospermum montanum?
The study aimed to evaluate the analgesic activity of the roots of Baliospermum montanum in albino rats, comparing its effects with the standard drug Diclofenac sodium.
How was the analgesic activity of the extracts tested?
Analgesic activity was tested using the tail-flick method in albino rats. The reaction times before and after administering the extracts were recorded to assess pain relief efficiency.
What were the results of the analgesic activity study?
The ethanolic extract and its chloroform soluble fraction showed significant analgesic activity. The activity was dose-dependent, with the best effects observed at doses of 100 mg/kg and 200 mg/kg.
What traditional uses does Baliospermum montanum have?
Baliospermum montanum is used in traditional medicine for various ailments, including abdominal tumors, wounds, and joint pain relief. Its analgesic properties are supported by both folklore and scientific findings.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Analgesic activity of the roots of baliospormum montanum linn”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
The term 'activity' refers to the measurable effects of the ethanolic extract and its fractions from Baliospermum montanum on pain relief in the study. It highlights the significance of evaluating medicinal plants for their pharmacological properties, which in this case is analgesic activity, further validating traditional uses of the plant.
2) Drug:
In the context of this study, 'drug' denotes any substance that is utilized for therapeutic purposes. The investigation compares the analgesic effects of Baliospermum montanum extracts with the standard drug, Diclofenac sodium, establishing whether the natural extracts can offer similar or improved medicinal benefits.
3) Medicine:
'Medicine' encompasses the science and practice of diagnosing, treating, and preventing illness. The study focuses on a traditional medicine, Baliospermum montanum, to assess its effectiveness and justify its historical use in treating pain, thereby bridging ancient practices with modern scientific scrutiny.
4) Science (Scientific):
'Scientific' pertains to the rigor of approach taken in the study. The employment of controlled experiments and statistical analyses ensures findings are valid, reproducible, and contribute to the body of knowledge regarding analgesic properties of herbal remedies like Baliospermum montanum.
5) Danti (Dantī, Dantin, Dānti, Damti):
'Danti' refers to the common name for Baliospermum montanum in local vernaculars. Understanding and utilizing local names can improve communication in ethnobotanical studies, highlighting the plant's cultural significance and traditional medicinal applications within specific communities.
6) Discussion:
'Discussion' is a pivotal section in research where the implications, interpretations, and significance of findings are analyzed. In this study, the discussion likely evaluates the analgesic effects observed, compares them with existing literature, and proposes avenues for future research while contextualizing the findings within traditional medicine.
7) Substance:
'Substance' in this context refers to the specific components derived from Baliospermum montanum that may exert pharmacological effects. The study investigates various extracts and their active constituents, thus exploring the relationship between the chemical makeup of the plant and its medicinal efficacy.
8) Ayurveda (Āyurveda, Ayus-veda):
'Ayurveda' is a traditional Indian system of medicine that emphasizes balance in bodily systems. The mention of Ayurveda in the study situates Baliospermum montanum within an established holistic medicinal framework, highlighting its historical use and the need for scientific validation of such practices.
9) Pungent:
'Pungent' describes the sharp, strong taste or odor that certain substances possess, often linked to their medicinal properties. In this text, pungency is associated with the therapeutic qualities of the plant molecules, suggesting that such characteristics contribute to its traditional applications in medicine.
10) Cancer:
'Cancer' signifies a group of diseases characterized by uncontrolled cell growth. Baliospermum montanum is reported to have applications in treating abdominal tumors and cancer, emphasizing the necessity of research into natural compounds for potential therapeutic agents against serious illnesses.
11) Botany:
'Botany' is the scientific study of plants, encompassing aspects like structure, properties, and biochemical processes. The involvement of botany in this research underscores the importance of understanding the plant's taxonomy and characteristics, which is integral to assessing its medicinal uses and ecological roles.
12) Water:
'Water' is essential for life and integral for the extraction processes used in the study, such as in the preparation of herbal remedies. The discussion of water serves to emphasize the basic requirements for plant growth and the critical role it plays in herbal medicine preparations.
13) Aman (Āman, A-man, Amaṇ, Āmāṉ):
'Aman' refers to one of the authors of the study. Recognizing the contributors is important as it lends credibility and traceability to the research. It highlights the collaborative effort necessary between researchers in the fields of pharmacy and medicinal sciences for such studies.
14) Diet:
'Diet' pertains to the customary course of food and drink consumed by the subjects in the study. The relevance of diet is crucial in pharmacological research as it may affect the metabolic responses and overall effectiveness of the administered extracts on the animals being studied.
Other Health Sciences Concepts:
Discover the significance of concepts within the article: ‘Analgesic activity of the roots of baliospormum montanum linn’. Further sources in the context of Health Sciences might help you critically compare this page with similair documents:
Jaundice treatment, Analgesic activity, Ethanolic extract, Diclofenac sodium, Tail-flick method, Active constituent, Chloroform Soluble Fraction, Folklore use, Dose dependant.