Anti inflammatory activity of moringa oliefera. lam
Journal name: Ancient Science of Life
Original article title: Anti inflammatory activity of moringa oliefera. lam
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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K.N. Venkataswera Rao, V. Gopalakrishnan, V. Loganathan, S. Shanmuganathan Nathan
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Anti inflammatory activity of moringa oliefera. lam
Year: 1999
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Moringa oleifera, commonly known as "sigru" in Sanskrit and "Soanjan" in Hindi, is a tree recognized for its extensive medicinal properties and frequently used in various herbal preparations. This study investigates the anti-inflammatory potential of both aqueous and ethanolic (90%) extracts of Moringa oleifera leaves using albino rats as subjects. The evaluation compared the efficacy of these extracts against a standard anti-inflammatory agent, Ibuprofen, with the aim of validating traditional claims regarding the plant's therapeutic benefits.
Anti-Inflammatory Efficacy of Moringa Oleifera Extracts
The research findings reveal that both the aqueous and ethanolic extracts demonstrated significant anti-inflammatory activity, particularly within two hours of administration. The aqueous extract produced marked oedema suppression, comparable to that of Ibuprofen, especially noted at the one-hour mark following carrageenan injection. The study suggests that the observed anti-inflammatory effects may be linked to the extracts' inhibitory actions on the release of certain mediators such as histamine and kinins during the early phase of carrageenan-induced oedema. The data indicate that the extracts effectively reduced inflammation, thereby supporting their use in traditional medicine.
Conclusion
The investigation into the anti-inflammatory properties of Moringa oleifera's leaf extracts provided compelling evidence of their therapeutic potential, aligning with traditional uses as claimed by various cultural practices. The aqueous extract, in particular, showed significant efficacy within a short time frame, reinforcing its value as a natural remedy. As the search progresses to identify the specific active compounds responsible for these effects, the results affirm the ongoing relevance of Moringa oleifera in both traditional and modern medicinal applications.
FAQ section (important questions/answers):
What was the aim of the study on Moringa Oleifera?
The study aimed to evaluate the anti-inflammatory activity of aqueous and ethanolic extracts of Moringa Oleifera leaves using albino rats and carrageenan-induced edema as a model.
What were the significant findings regarding the extracts' effects?
The aqueous extract showed maximum anti-inflammatory action comparable to Ibuprofen within 60 minutes of carrageenan injection, while both extracts exhibited significant edema suppression. Results confirmed the traditional use of Moringa Oleifera for inflammation.
How were the extracts prepared for testing?
Fresh Moringa Oleifera leaves were shade dried, powdered, and extracted using alcohol via a Soxhlet extractor and distilled water through decoction. The resulting residues were then used for the anti-inflammatory screening.
What statistical methods were utilized in the study's analysis?
The study used ANOVA for significance testing (P<0.01) to analyze the reduction in paw edema volumes, expressed as mean ± S.E., allowing for a comparison between the extracts and the control group.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Anti inflammatory activity of moringa oliefera. lam”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Edema (Oedema):
Oedema refers to the accumulation of fluid in tissues, leading to swelling. In the context of the study, the term is crucial as the anti-inflammatory effects of Moringa Oliefera are assessed by measuring oedema suppression in rats after carrageenan induction, highlighting the plant's potential therapeutic benefits against inflammation-related conditions.
2) Drug:
A drug is a chemical substance used for medical purposes, including healing, prevention, or diagnosis of disease. In this study, the extracts from Moringa Oliefera are tested as potential drugs to evaluate their efficacy in reducing inflammatory responses, emphasizing their role in pharmacological treatment against various ailments.
3) Inflammation:
Inflammation is the body's response to injury or infection, characterized by redness, heat, swelling, and pain. This study investigates the anti-inflammatory properties of Moringa Oliefera extracts, aiming to provide scientific validation for their traditional medicinal use in alleviating inflammatory conditions prevalent in various diseases.
4) Activity:
In this context, activity refers to the biological effects exhibited by substances. The study focuses on the anti-inflammatory activity of Moringa Oliefera extracts as compared to ibuprofen, thereby establishing their potential role in pharmacotherapy and demonstrating the importance of evaluating plant-derived compounds for medicinal uses.
5) Water:
Water is a solvent commonly used in extracting plant compounds due to its ability to dissolve a wide range of polar substances. The aqueous extract of Moringa Oliefera is part of the study, emphasizing its extraction method as a fundamental aspect of testing the plant's medicinal properties for anti-inflammatory effects.
6) Discussion:
The discussion section of a scientific study interprets results and relates them to existing knowledge. In this article, the discussion likely addresses the significance of the findings regarding Moringa Oliefera's plants and their potential applications, fostering a deeper understanding of their therapeutic relevance in traditional medicine.
7) Science (Scientific):
Science is a systematic enterprise that builds and organizes knowledge through observation and experimentation. The study exemplifies scientific inquiry by exploring Moringa Oliefera's medicinal properties, applying principles of pharmacology and biochemistry to establish the evidence for traditional medicinal claims using rigorous methodologies.
8) Substance:
A substance is a form of matter with a specific chemical composition. In this study, the term refers to the extracts from Moringa Oliefera and their chemical constituents that are responsible for anti-inflammatory actions, highlighting the critical interplay between chemical properties and biological activities in pharmacological research.
9) Flavonoid:
Flavonoids are a class of compounds with antioxidant and anti-inflammatory properties found in many plants, including Moringa Oliefera. The study mentions flavonoids in the context of their presence in the ethanolic extract, indicating their possible contribution to the observed anti-inflammatory activity and overall therapeutic potential of the plant.
10) Shigru (Śigru):
Sigru is the Sanskrit name for Moringa Oliefera, reflecting its cultural significance and traditional medicinal use in Indian systems of medicine. The mention of 'sigru' connects the plant to historical practices and underscores the relevance of ethnobotanical knowledge in contemporary scientific research, validating its applications.
11) Tera (Ṭēra, Ṭera, Ṭērā, Tēṟa):
In this context, 'Tera' likely refers to the journal or a typographical representation in citations mentioned in the study. However, if considered as a standalone term, it may intersect with broader scientific terminologies or methodologies that categorize research studies, evaluations, or pharmacological data pertaining to the tested extracts.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Anti inflammatory activity of moringa oliefera. lam’. Further sources in the context of Science might help you critically compare this page with similair documents:
Statistical analysis, Anti-inflammatory activity, Aqueous extract, Animal experimentation, Ethanolic extract, Carrageenan-induced oedema, Traditional medicinal system, Standard laboratory condition.