Standardisation of karpurasava

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Journal name: Ancient Science of Life
Original article title: Standardisation of karpurasava
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:

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Author:

Muzaffer Alam, K.K.S. Dasan, R. Bhima Rao


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Standardisation of karpurasava

Year: 1994

Copyright (license): CC BY-NC-SA


Download the PDF file of the original publication


Summary of article contents:

Introduction

The article discusses the standardization of Karpurasava, an Ayurvedic medicine created through fermentation. Asavas and arishtas, which fall under this category, involve the use of ingredients such as honey, sugar, or jaggery, mixed with a decoction of raw herbs, followed by fermentation. Karpurasava specifically includes distilled alcohol derived from fermented solutions, which is then blended with powdered drugs. This process serves not only to extract active compounds from the ingredients but also enhances the shelf life of the final product.

Importance of Alcohol Content in Karpurasava

The research highlights the significance of alcohol content in the formulation of Karpurasava. Two different distillation methods—glass distillation and the traditional bakayantra method—were compared to assess the alcohol levels in the prasanna used for preparation. The study revealed that the bakayantra method yielded approximately double the alcohol content compared to glass distillation, resulting in an end alcohol concentration of 8.7% in Karpurasava. This concentration aligns with the pharmacopoeial standards for Ayurvedic formulations, confirming that the alcohol content is dependent on the distillation method employed and reflects the quality of the prasanna.

Conclusion

The research concludes that the quantity of alcohol in Karpurasava is influenced by the distillation process of the prasanna, with consistent results across multiple batches indicating an average alcohol content of around 9.82%. Since the alcohol concentration in Ayurvedic medicines like Karpurasava should not exceed 10%, the findings affirm the compliance of Karpurasava with existing Ayurvedic standards. The study underscores the importance of establishing standardization processes for Ayurvedic remedies to ensure their efficacy and safety.

FAQ section (important questions/answers):

What is the main purpose of Karpurasava in Ayurveda?

Karpurasava is an Ayurvedic formulation prepared through fermentation, utilized for its medicinal properties. It extracts active principles from ingredients and enhances shelf life due to the alcohol content produced during fermentation.

How is Karpurasava prepared and what are its ingredients?

Karpurasava is made by mixing specific powdered drugs with prasanna, a fermented brew. Key ingredients include camphor, cardamom seeds, nut grass tubers, and dry ginger, mixed and left to ferment for several days before filtration.

What methods are used to determine the alcohol content in Karpurasava?

The alcohol content in Karpurasava is measured using both glass distillation and bakayantra methods. The average alcohol content found was 8.7%, indicating that the distillation technique significantly affects the final product's alcohol concentration.

What were the findings regarding alcohol content in the study?

The study concluded that the alcohol content in Karpurasava ranged from 8.7% to 10%. The average value observed across three batches was 9.82%, aligning with the permissible limits set for Ayurvedic formulations.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Standardisation of karpurasava”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Prasanna:
Prasanna refers to a fermented preparation utilized as a base for further distillation in Ayurvedic medicine. In the context of Karpurasava, prasanna serves as a critical ingredient, dictating the alcohol content and overall efficacy of the final product. Its preparation involves combining specific ingredients and allowing fermentation to extract active compounds.

2) Medicine:
Medicine denotes substances or compounds utilized for therapeutic purposes. In Ayurveda, the category encompasses various formulations including Asavas and Arishtas, which are prepared through fermentation. The preparation, composition, and standardization of these medicines aim to ensure health benefits, effective treatment of ailments, and safety for consumption.

3) Glass:
Glass is a material commonly used in laboratory equipment for distillation processes. In the study of Karpurasava, glass distillation apparatus was employed to measure the alcohol content during the preparation of prasanna. This method contrasts with the traditional bakayantra process, highlighting the variety of techniques in creating Ayurvedic medicines.

4) Asava (Āsava, Āśava, Ashava, Āsāva):
Asava stands for a type of Ayurvedic formulation made through fermentation, utilizing cold infusions or juices without the need for kashayam. This category of medicine relies on yeast fermentation to produce alcohol, enhancing the extraction of active ingredients and prolonging product shelf life, representing key elements of traditional Ayurvedic practices.

5) Drug:
Drug refers to any chemical substance used for its medicinal properties. In the Ayurvedic context, drugs consist of natural ingredients derived from plants, minerals, and other sources. The formulation of medicines such as Karpurasava showcases the intricate use of various drugs, each contributing to therapeutic effects and holistic healing.

6) Arishta (Ariṣṭa, Ariṣṭa, Ariṣṭā):
Arishta is another form of Ayurvedic fermented medicine, similar to Asava but typically involving ingredients like sugar or jaggery. Both formulations exploit fermentation to extract active medicinal principles. Arishtas are valued for their therapeutic applications, renowned for safety, and ability to enhance the body's natural healing processes.

7) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda is an ancient Indian system of medicine emphasizing balance within the body and harmony with nature. It integrates concepts of health, disease prevention, and holistic treatments. The preparation of medicines such as Karpurasava exemplifies Ayurvedic principles, involving herbal, dietary, and lifestyle approaches tailored to individual needs.

8) Haritaki (Harītakī):
Haritaki, also known as Terminalia chebula, is a revered medicinal herb in Ayurveda known for its health benefits, including digestive and detoxifying properties. It was one of the key ingredients used in creating prasanna, contributing to the overall effectiveness, healing potential, and synergistic qualities of formulations like Karpurasava.

9) Guda (Guḍa, Guḍā):
Guda, or jaggery, is an unrefined sugar made from sugarcane or palm sap. In Ayurvedic preparations, it acts as a natural sweetener and carrier for medicinal ingredients, enhancing taste while offering additional health benefits. In Karpurasava, guda plays a vital role in fermentation and the overall formulation.

10) Nut grass:
Nut grass, referred to as Ghana in this study, is a traditional herb recognized for its various health benefits. In the preparation of Karpurasava, its use in the formulation serves to enhance medicinal efficacy. Its biological properties contribute to the therapeutic profile of the final product.

11) Discussion:
Discussion refers to the analytical portion of the study where authors interpret results, comparing findings with existing knowledge. This section evaluates the effectiveness of the preparation methods and addresses discrepancies in alcohol content, thereby contextualizing the research's significance in Ayurvedic formulations and practices.

12) Kadambari (Kādambarī):
Kadambari signifies a classical Ayurvedic text which provides guidelines on the preparation of various medicinal products. The study of Karpurasava references methods elucidated in this text, highlighting the importance of traditional knowledge in contemporary practices and ensuring the authenticity of historical Ayurvedic formulation techniques.

13) Shringavera (Śṛṅgavera, Shringa-vera, Shrimgavera):
Srngavera, known as dry ginger, is a commonly used spice in Ayurvedic medicine for its warming properties and digestive benefits. Its incorporation into the prasanna preparation exemplifies the holistic approach of Ayurveda, as it complements other ingredients, enhancing the overall therapeutic profile of Karpurasava.

14) Jaggery:
Jaggery represents an unrefined sugar produced from sugarcane or palm sap, integral to Ayurvedic formulations. It acts as both a sweetener and a therapeutic agent, enabling better absorption of herbal properties. In Karpurasava, jaggery’s role underscores the blending of taste with health benefits in traditional medicines.

15) Science (Scientific):
Science pertains to the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. In the context of this article, it highlights the application of scientific methods in standardizing Ayurvedic formulations, juxtaposing traditional knowledge with empirical research for quality assurance.

16) Yantra (Yamtra):
Yantra refers to a device or instrument, particularly in the context of the bakayantra process used for distilling alcohol during the preparation of prasanna. This traditional method underscores the significance of specific tools and practices in Ayurvedic medicine, linking ancient techniques to contemporary research.

17) Siddha (Siddhā):
Siddha refers to another traditional system of medicine in India, closely related to Ayurveda. It emphasizes alchemical processes and herbal extracts, contributing rich wisdom to the understanding of health and healing. The cross-references between Siddha and Ayurveda are evidenced in shared practices like fermentation and specific ingredient use.

18) Kadali (Kadalī):
Kadali refers to the plantain used in the preparation of prasanna. As a food source, it enhances the nutritional value of the medicine and contributes to the fermentation process. Its use in Karpurasava exemplifies how familiar food items can play a role in Ayurvedic medicinal formulations.

19) Bhava (Bhāva):
Bhava signifies the essence or emotion in the production of Ayurvedic medicines or texts. In this context, it encompasses philosophical underpinnings and theoretical approaches towards herbal preparations, especially in the writings that outline standardized processes like those referenced in Karpurasava's preparation method.

20) Madya:
Madya translates to 'intoxicating beverage,' signifying the role of fermented substances in traditional medicine. In the context of Karpurasava, it reflects the alcohol content derived from fermentation, reminding us of the balance between therapeutic benefits and careful consumption associated with such Ayurvedic formulations.

21) Ghana (Ghanā, Ghāṇa, Ghāna):
Ghana refers to nut grass, an herb noted for its various health benefits in Ayurvedic traditions. Its incorporation into Karpurasava symbolizes the synergistic use of plants, facilitating better health outcomes by combining multiple herbs in one formulation for enhanced therapeutic effectiveness.

22) Water:
Water acts as a fundamental solvent and medium for the extraction of medicinal properties during the preparation of Ayurvedic formulations. In Karpurasava, water's role in creating decoctions or infusions is crucial for activating the ingredients, showcasing its indispensable function in effective herbal preparation processes.

23) Apa (Āpa, Āpā, Pappa, Pāppā):
Pappa refers to a contributor in the research process, indicating the collaborative effort behind the study. Involving individuals like Pappa highlights the importance of teamwork in scientific research, ensuring the successful execution, analysis, and reporting of Ayurvedic medicinal formulations such as Karpurasava.

24) Sugar:
Sugar denotes various sweeteners utilized in Ayurvedic formulations, serving to enhance palatability and potentially impart therapeutic properties. The combination of sugar with other herbal ingredients in Karpurasava underscores Ayurveda's holistic approach, where taste and health-centric formulations go hand-in-hand to ensure user acceptance and efficacy.

25) Honey:
Honey is a natural sweetener with recognized health benefits, widely used in Ayurvedic medicine. Its inclusion in formulations not only enhances taste but also contributes to the therapeutic effects. In Karpurasava, honey acts as a vital component, enriching the medicine's overall quality and beneficial properties.

26) Dasa (Dāsa, Daśā, Dasā, Daśa, Dāśa, Daśan, Dasha, Dashan):
Dasan refers to one of the authors contributing to the research on Karpurasava. The involvement of individuals with expertise in Ayurvedic practice highlights the importance of academic and practical knowledge in standardizing and validating traditional formulations, bridging historical practices with scientific methodologies.

27) Baka (Bakā):
Baka refers to the traditional distillation apparatus utilized in the preparation of prasanna through the bakayantra method. Its use illustrates the ancient techniques employed in Ayurvedic medicine, demonstrating the intricate craftsmanship and knowledge necessary for effective production of herbal formulations, such as Karpurasava.

28) Rice (Ṛce):
Rice, represented here as Sashitka (Navarai rice), signifies an essential ingredient in the preparation of prasanna. It plays a key role in fermentation, contributing to the overall formulation and functioning of Karpurasava. Its foundational status in Ayurvedic recipes underscores the blend of nutrition and medicinal efficacy.

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Fermentation process, Alcohol content, Filtration Process, Analytical values, Preparatory method, Alcohol extraction.

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