Effect of isapgul on serum lipids
Journal name: Ancient Science of Life
Original article title: Effect of isapgul on serum lipids
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Shashikant Goswami
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Effect of isapgul on serum lipids
Year: 1988
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
The ingestion of dietary fiber has garnered significant attention for its potential health benefits, particularly in reducing the risk of various diseases such as colon cancer, diverticulitis, diabetes, and cardiovascular conditions. The dietary fiber hypothesis, proposed by Burkitt and Trowell, posits that the modern decline in fiber consumption due to the prevalence of refined flour may be linked to an increase in disease incidence among industrialized populations. One specific type of dietary fiber, Isapgul, is recognized for its natural laxative properties and its ability to enhance stool production, though its effects on lipid profiles have been less studied. This study aimed to evaluate the hypolipidaemic effect of Isapgul.
Effect of Isapgul on Serum Lipids
In a controlled study involving fourteen healthy volunteers, participants ingested a daily dose of 10 grams of Isapgul for one month. Subsequent blood tests revealed a significant reduction in serum lipids, demonstrating a 9.6% decrease in total serum cholesterol, from an average of 171.3 mg/dl to 154.8 mg/dl, and an 8.6% decrease in triglyceride levels, from 164.3 mg/dl to 150.2 mg/dl. Notably, 10 out of the 14 participants experienced a decline in cholesterol levels ranging from 10 mg/dl to 39 mg/dl, while triglyceride levels decreased in 11 cases. These findings build upon previous research, indicating that a similar intervention with a higher dosage of Isapgul over a longer duration also yielded notable reductions in cholesterol levels.
Conclusion
The study suggests that regular intake of Isapgul can effectively lower serum cholesterol and triglyceride levels in healthy individuals, aligning with existing literature that supports the cardiovascular benefits of dietary fiber. The notable reductions observed in lipid profiles underscore the potential for Isapgul as a functional food in managing serum lipids. However, further long-term studies are warranted to explore the effects on specific lipoprotein fractions and to establish more comprehensive insights into the health benefits of this water-soluble fiber.
FAQ section (important questions/answers):
What was the objective of the Isapgul study?
The study aimed to evaluate the effects of daily ingestion of Isapgul on serum lipid levels, particularly total cholesterol and triglycerides, in healthy volunteers over a month.
What was the daily dosage of Isapgul used in the study?
Participants ingested 10 grams of Isapgul daily, mixed with water or milk, for a duration of one month to assess its impact on serum lipid levels.
What were the main findings regarding cholesterol and triglyceride levels?
After one month, total serum cholesterol levels decreased by 9.6%, and triglycerides fell by 8.6%, indicating that Isapgul may have beneficial effects on lipid profiles.
How did Isapgul perform compared to previous studies?
Previous studies, like that of Nakamura et al., indicated a 14.4% reduction in cholesterol with a higher dosage. The differences in findings suggest that further research is needed.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of isapgul on serum lipids”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Water:
Water is essential for the ingestion of Isapgul, a dietary fiber that requires a fluid medium to be effective in reducing serum lipids. The study highlights the importance of consuming Isapgul mixed with water or milk to facilitate digestion and absorption, emphasizing the interplay between hydration and fiber efficacy in health management.
2) Discussion:
The discussion section of a study allows for interpretation of results and their implications. It is crucial for understanding how the ingestion of Isapgul impacts serum lipid levels. The analysis of varying responses among individuals illustrates the necessity of discussing findings in the context of broader dietary practices and individual health variations.
3) Science (Scientific):
Science underpins the investigation of Isapgul’s effects on serum lipids. The systematic approach to determining the biochemical changes illustrates the scientific method's role in establishing facts. Quantitative measurements of cholesterol and triglycerides provide evidence of Isapgul's potential health benefits, emphasizing the importance of scientific inquiry in nutritional studies.
4) Cancer:
Cancer, particularly colon cancer, has been linked to low dietary fiber intake. The study references the dietary fiber hypothesis as a protective factor against this disease. By exploring Isapgul's role as a fiber source, the research highlights dietary adjustments that may reduce cancer risk, showcasing the significance of preventive nutrition in public health.
5) Blood:
Blood tests are a critical aspect of assessing the effects of Isapgul on serum lipids. The study measures cholesterol and triglyceride levels in fasting blood samples before and after dietary intervention. This quantifiable data helps establish a clear link between Isapgul intake and changes in blood lipid profiles, emphasizing the relationship between diet and cardiovascular health.
6) Diet:
Diet is central to the research, as it investigates the impact of Isapgul on serum lipid profiles, indicative of dietary choices. The study underscores the importance of dietary fiber as part of a healthy diet, particularly in modern contexts where refined foods predominate, demonstrating how dietary modifications can contribute to health improvements.
7) Milk:
Milk serves as a medium for consuming Isapgul, enhancing its palatability and aiding in its effectiveness. As part of the study methodology, mixing the fiber with milk provides an alternative to water that may improve compliance and digestion, highlighting the multi-faceted role of food pairings in health-oriented dietary practices.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Effect of isapgul on serum lipids’. Further sources in the context of Science might help you critically compare this page with similair documents:
Diabetes, Dietary fiber, Serum lipids, Diverticulitis, Colon cancer, Triglyceride level, Atherosclerotic cardiovascular disease, Health benefit, Long-term study, Total serum cholesterol.