An Ayurvedic perspective of Mutrashmari - Urinary Calculi along with Crystal...

[Full title: An Ayurvedic perspective of Mutrashmari - Urinary Calculi along with Crystal Morphology]

[Find the meaning and references behind the names: Patil, Vijay, Joshi, Ayu, Prakash, Vinayak, Nil, Med, Crystal]

Journal of Ayurveda and Integrated Medical Sciences 2025 Volume 10 Number 3 MARCH E-ISSN:2456-3110 Case Report Crystal Morphology Publisher www.maharshicharaka.in An Ayurvedic perspective of Mutrashmari - Urinary Calculi along with Crystal Morphology Solanki NV 1 , Mane P 2* , Joshi V 3 DOI:10.21760/jaims.10.3.63 1 Nivedita Vijay Solanki, Post Graduate Scholar, Department of Rog Nidan, Dr DY Patil College of Ayurved and Research Centre, Pimpri, Pune, Dr DY Patil Vidyapeeth, Pune (Deemed to be University), Maharashtra, India 2* Prakash Mane, Professor, Department of Rog Nidan, Dr DY Patil College of Ayurved and Research Centre, Pimpri, Pune, Dr DY Patil Vidyapeeth, Pune (Deemed to be University), Maharashtra, India 3 Vinayak Joshi, Professor and HOD, Department of Rog Nidan, Dr DY Patil College of Ayurved and Research Centre, Pimpri, Pune, Dr DY Patil Vidyapeeth, Pune (Deemed to be University), Maharashtra, India Background: Microscopic evidence based Urinary Crystal Morphology would help Ayurveda physicians to give appropriate Ayurvedic treatment to Mutrashmari patients. Urinary calculi affected 22.1 million people in 2015 with 16,100 deaths worldwide Aim: To study the correlation of Urinary calculi with Mutrashmari along with Crystal Morphology Objective: To observe the correlation of Urinary calculi with Mutrashmari along with Crystal Morphology Material and Methods: It includes Literature Review, Initial assessment & enrollment of patients, Microscopic observational changes to correlate Urinary Calculi with Mutrashmari, Observation & Interpretation Results: It shows the correlation of Urinary Calculi with Mutrashmari along with Crystal Morphology Conclusion: This study finds the correlation of Urinary Calculi with Mutrashmari along with Crystal Morphology. This study would help Ayurveda physicians to give appropriate Ayurvedic treatment to Urinary Calculi patients on the basis of evidence based Crystal Morphology Keywords: Lakshana, Samprapti, Mutrashmari, Calculi Corresponding Author How to Cite this Article To Browse Prakash Mane, Professor, Department of Rog Nidan, Dr DY Patil College of Ayurved and Research Centre, Pimpri, Pune, Dr DY Patil Vidyapeeth, Pune (Deemed to be University), Maharashtra, India Email: Solanki NV, Mane P, Joshi V, An Ayurvedic perspective of Mutrashmari - Urinary Calculi along with Crystal Morphology . J Ayu Int Med Sci. 2025;10(3):407-411 Available From https://jaims.in/jaims/article/view/4183/ Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted 2025-02-11 2025-02-27 2025-03-07 2025-03-17 2025-03-27 Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note None Nil Not required 11.64 © 2025 by Solanki NV, Mane P, Joshi V and Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0] J Ayu Int Med Sci 2025 ; 10 ( 3 ) 407

[Find the meaning and references behind the names: Sita, Low, Madhav, Guru, Honey, Min]

Introduction Kidney stone disease is a crystallopathy and occurs when there are too many minerals in the urine and not enough liquid or hydration. This imbalance causes tiny pieces of crystal to aggregate and form hard masses or calculi in upper urinary tract Because renal calculi typically form in the kidney, if small enough, they are able to leave the urinary tract via urine stream. A small calculus may pass without causing symptoms However, if stone grows to more than 5 mm it can cause blockage of ureter resulting in excruciating intermittent pain that radiates from the flank to the groin or to the inner thigh. This is due to transfer of referred pain signals from lower thoracic splanchicn nerves to lumbar splanchic nerves as stone passes down from kidney or proximal ureter to distal ureter Between 1% and 15% of people globally are affected by renal calculi at some point in the liver. In 2015,22.1 million cases occurred resulting in about 16,100 deaths. They have become more common in western world since the 1970’s. Generally more men are affected than women The prevalence and incidence of the disease rises worldwide and continues to be challenging for patients, physicians and healthcare systems. Renal colic caused by kidney stones is commonly accompanied by urine urgency, restlessness, haematuria, sweating, nausea and vomiting It typically comes in waves lasting 20 to 60 min caused by peristaltic contraction of ureter as it attempts to expel stone. Risk factors include dehydration from low fluid intake, warm climate, obesity, immobility, sedentary lifestyle, high dietary intake of animal protein, sodium, sugar including honey, refined sugar, high fructose, corn syrup, excessive consumption of fruit juices etc According to Ayurveda Mutrashmari is तुल्यताश्मणा यांती त ात्ताश्म र िवदु : I In Ayurveda there are 4 types of Mutrashmari explained i.e., Vataj, Pittaj, Kaphaj & Shukraj. According to Sushruta Hetus of Mutrashmari include Divaswaap, Samashan, Adhyashan, Shita, Snigdha, Guru, Madhur Aahaar Sevan According to Madhav Nidan Lakshana includes Mutrakruchrataa, Jwar, Aruchi, Ashmatulya Vedana, Mutra Rujaa, Basti Shool, Vishirnadhaaryukta Mutra, Medhra Pradeshi Vedana, Mutra Margaavarodh, Sarakta Mutrapravrutti, Bastidaha, Bastitod Shaitya and Gurutva, Vrushan Shotha According to Charak Samprapti of Mutrashmari is described as: िवशोषयदबा ीगतं सशुक्रम् मूत्रम् स िपत्तम् पवन : कफम् वा I यदा तदाष्मऱ्यूपजायते तु क्रमेण िपत्तेषिवव रोचना गो : II ( च िच २६ / ३६ ) Material and Methods Initial assessment & Enrollment with written consent ↓ Microscopic observational changes to correlate Urinary Calculi with Mutrashmari ↓ Assessment criteria along with Crystal Morphology ↓ Observation, Interpretation & Statical Analysis Total 5 number of patients are enrolled in this study and correlated with Urinary Calculi i.e., Mutrashmari along with Crystal Morphology Microscopic observational changes to correlate Urinary Calculi with Mutrashmari along with Crystal Morphology as follows :- Calcium Oxalate Crystals Nivedita VS et al. An Ayurvedic perspective of Mutrashmari J Ayu Int Med Sci 2025 ; 10 ( 3 ) 408

Focused Calcium Oxalate Crystals Calcium Oxalate Mature & Immature forms Calcium Carbonate Crystals Calcium Oxalate & Carbonate Crystals Uric Acid Crystals Focused Uric Acid Crystals Nivedita VS et al. An Ayurvedic perspective of Mutrashmari J Ayu Int Med Sci 2025 ; 10 ( 3 ) 409

[Find the meaning and references behind the names: Sharma, Bharti]

Triple Phosphate Crystals Tyrosine Needles Tyrosine Needles Observations It is observed that Mutrashmari can be correlated with Urinary Calculi along with Crystal Morphology with the help of Patient’s Data as follows: Total 5 number of patients are enrolled and all of them shows various crystal morphologies shown above Results This study shows the correlation of Urinary Crystals with Mutrashmari along with Crystal Morphology Conclusion This study finds correlation of Urinary Crystal with Mutrashmari along with Crystal Morphology. This study would help Ayurveda physicians to give appro Ayurvedic treatment to Urinary Calculi patients on basis of evidence based Crystal Morphology References 1. Shastri K, Kale VS, editors. Charaka Samhita Chikitsa Sthana. 26/36. Varanasi: Chaukhamba Bharti Academy; 2005. [Crossref][PubMed][Google Scholar] 2. Shastri K, Kale VS, editors. Charaka Samhita Chikitsa Sthana. 26/35. Varanasi: Chaukhamba Bharti Academy; 2005. [Crossref][PubMed][Google Scholar] 3. Sharma P, editor. Sushruta Samhita Nidan Sthana. 3/4. Varanasi: Chaukhamba Orientalia; 2003. [Crossref][PubMed][Google Scholar] 4. Sharma P, editor. Sushruta Samhita Nidan Sthana. 3/24. Varanasi: Chaukhamba Orientalia; 2003. [Crossref][PubMed][Google Scholar] 5. Sharma P, editor. Sushruta Samhita Nidan Sthana. 3/25. Varanasi: Chaukhamba Orientalia; 2003. [Crossref][PubMed][Google Scholar] 6. Sharma P, editor. Sushruta Samhita Nidan Sthana. 3/26. Varanasi: Chaukhamba Orientalia; 2003. [Crossref][PubMed][Google Scholar] 7. Sharma P, editor. Sushruta Samhita Nidan Sthana. 3/27. Varanasi: Chaukhamba Orientalia; 2003. [Crossref][PubMed][Google Scholar] 8. Madhavakara. Madhav Nidan Ashmari Adhyay. Shlok 3. Varanasi: Chaukhambha Surabharathi; 2008. [Crossref][PubMed][Google Scholar] 9. Madhavakara. Madhav Nidan Ashmari Adhyay. Shlok 4. Varanasi: Chaukhambha Surabharathi; 2008. [Crossref][PubMed][Google Scholar] Nivedita VS et al. An Ayurvedic perspective of Mutrashmari J Ayu Int Med Sci 2025 ; 10 ( 3 ) 410

[Find the meaning and references behind the names: Henry]

10. Madhavakara. Madhav Nidan Ashmari Adhyay. Shlok 5. Varanasi: Chaukhambha Surabharathi; 2008. [Crossref][PubMed][Google Scholar] 11. Wikipedia. Kidney stone disease [Internet]. Available from: https://en. wikipedia org/wiki/Kidney_stone_disease [Crossref][PubMed] [Google Scholar] 12. Kawthalkar SM. Essentials of Clinical Pathology. Section I: Clinical Chemistry & Other Laboratory Tests. Chapter 2: Examination of Urine. New Delhi: [Publisher]; [year] [Crossref][PubMed][Google Scholar] 13. Henry’s Clinical Diagnosis & Management by Laboratory Methods. Part 3: Urine & Other Bodily Fluids. Chapter 28: Basic Examination of Urine. [Publisher]; [year]. [Crossref][PubMed][Google Scholar] 14. Images of crystal morphology from Microbiology Section of Pathology Laboratory, Dr. D. Y. Patil College of Ayurveda & Research Centre, Pimpri, Pune-411018, Maharashtra, India. [Crossref] [PubMed][Google Scholar] Disclaimer / Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of Journals and/or the editor(s). Journals and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content Nivedita VS et al. An Ayurvedic perspective of Mutrashmari J Ayu Int Med Sci 2025 ; 10 ( 3 ) 411

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Ayurvedic treatment, Urinary calculi, Conflict of interest, Renal calculi, Mutrashmari, Calcium oxalate, Ayurveda physician, Ethical approval, Kidney Stone, Risk factor, Open Access, Renal colic, Calcium oxalate crystal, Corresponding author, Uric Acid Crystals, Initial assessment, High dietary intake, Charaka Samhita Chikitsa.