Breath of Life

[Full title: Breath of Life: The Therapeutic Role of Pranayama in Enhancing Respiratory Health and Quality of Life in Cancer Care]

[Find the meaning and references behind the names: Yogi, Long, Krishna, Deep, Ramya]

REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 114 Breath of Life: The Therapeutic Role of Pranayama in Enhancing Respiratory Health and Quality of Life in Cancer Care Anantha Krishna B S 1 , Ramya S 2 1 Specialist Yoga and Wellness, Department of Yoga and Wellness, Solis Health, Bangalore, Karnataka, India. 2 Psychologist, Psycho-social Department, Solis Health, Bangalore, Karnataka, India. I NTRODUCTION Pranayama , derived from the Sanskrit word Prana (life force or vital energy) and Ayama (expansion or control), represents a fundamental aspect of classical Yoga , emphasizing the regulation of breath to influence the body and mind. Historically, Pranayama practices have been integral to yogic traditions and recognized for their profound impact on physical, Address for correspondence: Dr. Anantha Krishna B S Specialist Yoga and Wellness, Department of Yoga and Wellness, Solis Health, Bangalore, Karnataka, India. E-mail: anantha@solis.health Submission Date: 15/08/2024 Accepted Date: 27/09/2024 Access this article online Quick Response Code Website: www.jaims.in DOI: 10.21760/jaims.9.9.18 mental, and spiritual well-being. The Hatha Yoga Pradipika, [1] a seminal text on Hatha Yoga , underscores the significance of Pranayama with the Shloka : "Chale Vate Chalam Chittam, Nischale Nischalam Bhavet | Yogi Sthanutvamapnoti Tato Vayum Nirodhayet" || (When the breath wanders, the mind is unsteady, but when the breath is calmed, the mind too will be still, and the yogi achieves steady mind and stillness.) - Hatha Yoga Pradipika, Chapter 2, Verse 2 In modern healthcare, particularly cancer care, Pranayama has garnered attention for its potential to enhance respiratory function, alleviate treatmentrelated symptoms, and improve overall quality of life [2] Cancer treatments, such as chemotherapy and radiation therapy, often lead to significant respiratory challenges, including dyspnea, reduced lung capacity, and decreased oxygenation [3,4] Additionally, the psychological burden of cancer diagnosis and A B S T R A C T This review systematically examines the therapeutic potential of Pranayama - controlled breathing techniques - in enhancing respiratory health and overall quality of life for cancer patients. The article provides a detailed analysis of key Pranayama practices, including Deep Breathing, Nadi Shodhana , Kapalabhati , and Bhramari , focusing on their physiological mechanisms and clinical impacts. Evidence suggests that these practices significantly improve pulmonary function, enhance oxygen saturation, and alleviate symptoms such as breathlessness - crucial factors in managing the respiratory challenges associated with cancer treatment. Furthermore, Pranayama has demonstrated efficacy in reducing psychological distress, including anxiety, depression, and stress, thereby improving emotional resilience and mental clarity in cancer patients. The review highlights the integration of Pranayama into oncology care, proposing practical, evidence-based guidelines for its safe and effective application. It also identifies critical research gaps, including the need for studies on personalized Pranayama protocols, the long-term effects on cancer survivorship, and the utilization of digital health technologies to enhance accessibility. By bridging traditional yogic practices with contemporary cancer care, Pranayama is presented as a complementary, holistic intervention that supports both physical recovery and emotional well-being, contributing to a higher quality of life for cancer patients. Key words: Pranayama, Cancer Care, Respiratory Health, Quality of Life, Stress Reduction, Holistic Therapy

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 115 treatment exacerbates stress, anxiety, and overall mental distress, further impacting patients' quality of life [5] Pranayama offers a holistic approach to addressing these challenges by leveraging controlled breathing techniques to optimize respiratory efficiency, enhance oxygenation, and modulate stress responses [6] . Techniques such as diaphragmatic breathing, Nadi Shodhana (alternate nostril breathing), and Kapalabhati (skull-shining breath) have been shown to influence autonomic nervous system regulation, improve pulmonary function, and support emotional resilience [7] . Emerging clinical evidence highlights the role of Pranayama in enhancing lung function, reducing breathlessness, and improving psychological wellbeing among cancer patients. Integrating Pranayama into cancer care protocols offers a non-invasive, costeffective adjunct to conventional treatments, contributing to comprehensive patient care [8] . O BJECTIVES This review aims to explore and synthesize the benefits of Pranayama in enhancing respiratory health and quality of life for cancer patients. By examining clinical studies, physiological mechanisms, and practical applications, the review seeks to provide a thorough understanding of how Pranayama can be effectively integrated into cancer care strategies. This comprehensive review underscores the therapeutic potential of Pranayama , advocating for its inclusion as a supportive intervention in the holistic management of cancer patients. M ETHODOLOGY The methodology for this review involved a comprehensive analysis of existing literature on Pranayama and its effects on respiratory health and quality of life in cancer care. Databases such as PubMed, ResearchGate, and Google Scholar were searched using keywords like " Pranayama ," "cancer care," and "respiratory health." Studies were selected based on relevance, clinical evidence, and the inclusion of Pranayama techniques in cancer treatment protocols. Physiological Mechanisms of Pranayama Pranayama , a core component of yogic practice, involves controlled breathing techniques that regulate the flow of prana (vital energy) throughout the body. This regulation not only influences physical processes but also profoundly affects mental and emotional states, making Pranayama a valuable practice for cancer patients facing complex challenges [9] This section explores the physiological mechanisms of four key Pranayama techniques - Deep Breathing, Nadi Shodhana , Kapalabhati , and Bhramari - and their relevance to cancer care. Deep Breathing (Diaphragmatic Breathing) Deep breathing, or diaphragmatic breathing, is a foundational Pranayama technique that significantly impacts the nervous system by promoting relaxation and enhancing respiratory efficiency [10] . This practice involves controlled, slow, and rhythmic inhalation and exhalation, which stimulates the parasympathetic nervous system, leading to a calming effect on both the body and mind. The Yoga Sutras of Patanjali [11] highlights the importance of Pranayama as a bridge between physical postures and deeper meditative states. Specifically, Yoga Sutra 2.49 states: “ Tasmin Sati Śvāsa Praśvāsayor Gati Vicchedaḥ Prāṇāyāmaḥ” (" Pranayama is the regulation of the incoming and outgoing breath, which follows after mastering posture.") This emphasizes the role of breath regulation in calming the mind and stabilizing the nervous system. Deep breathing reduces stress and anxiety by modulating the autonomic nervous system [12] By extending the exhalation and regulating the breath, it induces a state of relaxation, which is particularly beneficial for cancer patients dealing with high levels of stress and respiratory challenges [13] This practice not only enhances oxygenation but also promotes mental tranquility, aiding in the overall well-being of the patient.

[Find the meaning and references behind the names: Buddhi, Joy, Gita, Heart]

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 116 Nadi Shodhana (Alternate Nostril Breathing) Nadi Shodhana , or alternate nostril breathing, is a Pranayama technique that balances the flow of breath through the nostrils, improving respiratory function and mental clarity. This practice enhances the regulation of respiratory cycles and contributes to overall respiratory health [14] It is believed to influence cognitive function and emotional stability, potentially through its effects on autonomic centres in the brain. Yoga philosophy underscores the profound connection between the mind and breath, highlighting their interplay in achieving mental clarity and emotional stability. According to the Bhagavad Gita, this relationship is essential for attaining transcendental happiness: " Sukham Atyantikam Yat Tad Buddhi- Grahyam Atindriyam Vetti Yatra Na Chaivayam Sthitash Chalati Tattvatah" (Bhagavad Gita 6.21) [15] This verse illustrates that happiness derived from inner steadiness and control of the senses, including the breath, leads to a stable and peaceful mind. The classical texts emphasize that mastering breath control, or Pranayama , is crucial for achieving a calm and focused mind, highlighting the deep and intrinsic connection between breath regulation and mental well-being in Yoga practice. Kapalabhati (Skull Shining Breath) Kapalabhati , or "Skull Shining Breath," is a dynamic Pranayama technique involving forceful exhalations and passive inhalations. It stimulates the respiratory centres in the brain, enhances gas exchange, and promotes carbon dioxide expulsion, effectively clearing nasal passages and reducing mucus accumulation [16] The Gheranda Samhita [17] highlights its benefits: “Kapālabhātir Vāyukramaḥ Kaphado ṣaviśoṣ a ṇ a ḥ” (" Kapalabhati is a practice that removes disorders caused by phlegm and purifies the frontal sinuses.") This verse emphasizes Kapalabhati 's ability to cleanse the frontal sinuses and reduce Kapha Dosha (excess mucus), which can obstruct airways. Beyond its physical effects, Kapalabhati is believed to purify the mind, fostering mental clarity and emotional stability. For cancer patients, this practice supports respiratory health, balances autonomic functions, and enhances overall vitality, making it a valuable component of integrative cancer care aimed at improving both respiratory function and quality of life. Bhramari (Bee Breath) Bhramari Pranayama , or "Bee Breath," involves a humming exhalation, mimicking a bee's buzz, and is known for its calming and meditative effects. This practice activates the parasympathetic nervous system, stimulating the vagus nerve, which reduces heart rate and blood pressure, fostering deep relaxation [18] For cancer patients, who often face high stress and anxiety, this relaxation is crucial. Bhramari also enhances respiratory function by boosting nitric oxide production in the nasal passages, improving airway openness and oxygenation - key for those undergoing cancer treatment. The Hatha Yoga Pradipika captures Bhramari 's mental benefits: “Chitte Jata Kāchit Ānandaleela” ("The mind experiences a certain blissful play, a sense of joy and tranquility.") This verse reflects the practice's ability to bring mental clarity and contentment. For cancer patients, Bhramari offers psychological and physiological advantages, helping manage emotional challenges, improving lung function, and fostering inner peace, making it a vital component in integrative cancer care. Physiological Impact of Pranayama Effects on Autonomic Nervous System Regulation Pranayama , with its controlled breathing techniques, has a profound impact on the autonomic nervous system (ANS), which governs involuntary bodily functions such as heart rate, digestion, and respiration [19] Research shows that Pranayama practices like Nadi Shodhana (alternate nostril breathing) and Bhramari (bee breath) enhance parasympathetic activity, reducing sympathetic dominance [20] This shift towards parasympathetic dominance results in a decrease in heart rate, lower

[Find the meaning and references behind the names: Sudarshan]

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 117 blood pressure, and increased heart rate variability (HRV), all indicators of a balanced and resilient ANS. Studies have found that regular Pranayama practice significantly lowers cortisol levels, a key stress hormone, thereby promoting relaxation and stress relief through better autonomic regulation [21] Improvement in Oxygenation and Respiratory Efficiency Pranayama also improves respiratory efficiency and oxygenation, essential for maintaining cellular function and overall health [22] Techniques like Deep Breathing (diaphragmatic breathing) and Kapalabhati (skullshining breath) are particularly effective in enhancing lung function by increasing tidal volume and vital capacity. These practices promote full utilization of the diaphragm, leading to more efficient gas exchange and better alveolar ventilation [23] This is particularly crucial for cancer patients, who often experience compromised respiratory function due to the disease or its treatment. Studies have demonstrated that these Pranayama practices can increase arterial oxygen saturation and reduce carbon dioxide levels in the blood, supporting better respiratory health [24] Furthermore, Pranayama strengthens the respiratory muscles, promoting a more efficient breathing pattern and facilitating the work of breathing, which is especially beneficial for patients with lung-related issues common in cancer care. Influence on the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Stress Response The hypothalamic-pituitary-adrenal (HPA) axis, which plays a central role in the body's stress response, [25] is also positively influenced by Pranayama . Dysregulation of the HPA axis is often associated with chronic stress and anxiety, but Pranayama can help modulate this system, lowering cortisol levels and mitigating stress [26] Studies have shown that practices like Sudarshan Kriya , a form of rhythmic breathing, can significantly reduce cortisol levels and enhance psychological well-being [27] By activating the parasympathetic nervous system (PNS) and dampening the activity of the sympathetic nervous system (SNS) and HPA axis, Pranayama fosters a more resilient stress response system, which is particularly beneficial for cancer patients facing the psychological and emotional challenges of their illness and treatment. Pranayama offers extensive physiological benefits, including regulating the autonomic nervous system, improving respiratory efficiency, and modulation of the HPA axis. These effects collectively contribute to the physical and psychological resilience of cancer patients, highlighting the potential of Pranayama as a valuable complementary therapy in cancer care. Clinical Evidence of Pranayama in Cancer Care Respiratory Health Pranayama , a controlled breathing technique, significantly enhances respiratory health in cancer patients. Research shows that Pranayama improves lung capacity and oxygen saturation and reduces breathlessness, which is crucial for respiratory function [28] Additionally, Pranayama has been found to increase arterial oxygen saturation (SpO₂), essential for cellular metabolism [29] A study reported significant SpO₂ improvements in patients practicing diaphragmatic breathing, which will especially benefit those with hypoxemia, a common cancer-related condition [30] Pranayama also effectively alleviates breathlessness. Practicing Bhramari (bee breath) demonstrated a significant reduction in dyspnea, improving respiratory comfort [31] Moreover, a study highlighted Pranayama ’s dual benefits over conventional respiratory techniques, such as spirometry, by not only enhancing respiratory function but also reducing stress, making it a holistic approach to respiratory health in cancer care [32] Psychosocial Well-being Pranayama also plays a crucial role in improving the psychosocial well-being of cancer patients by reducing anxiety, depression, and stress. Numerous studies have demonstrated its effectiveness in mitigating these symptoms, which are common among individuals undergoing cancer treatment. For example, a study found that breast cancer patients practicing Pranayama experienced significant reductions in anxiety and depression [33] These

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 118 improvements are linked to Pranayama ’s ability to modulate autonomic nervous system activity, enhance parasympathetic tone, and promote emotional regulation. Pranayama has also been shown to reduce stress levels significantly. This stress reduction is critical, as chronic stress can exacerbate disease progression and hinder recovery. Moreover, Pranayama enhances emotional resilience, helping patients better cope with the emotional challenges of cancer. A study revealed that patients practicing Pranayama demonstrated improved coping mechanisms and reduced emotional reactivity, contributing to better overall mental health [34] Quality of Life Pranayama significantly improves the quality of life (QoL) for cancer patients by enhancing physical, emotional, and functional well-being. Physically, it boosts respiratory function, reduces fatigue, and alleviates pain. A study found notable reductions in pain and fatigue among patients practicing Pranayama , contributing to greater comfort during treatment [33] Emotionally, Pranayama helps reduce anxiety and depression, leading to improved mood and emotional stability [35] Functionally, it aids in maintaining daily activities, which is crucial for patients facing treatmentrelated impairments. Patients consistently report high satisfaction with Pranayama , noting increased relaxation, better breath control, and an enhanced sense of well-being. These subjective benefits, coupled with objective clinical improvements, highlight Pranayama ’s holistic impact, making it a valuable complementary therapy in cancer care. Integration of Pranayama into Multimodal Cancer Care Complementary Role Pranayama , an ancient practice of controlled breathing, serves as an effective complementary therapy in cancer treatment, enhancing the efficacy and tolerability of chemotherapy, radiation, and surgery. By addressing both the physical and emotional challenges of these treatments, Pranayama supports overall well-being and improves treatment outcomes. Pranayama as an Adjunct to Chemotherapy, Radiation, and Surgery Chemotherapy often induces side effects such as fatigue and respiratory complications. Integrating Pranayama into chemotherapy regimens has shown promising results in alleviating these issues. Studies have demonstrated that patients practicing Pranayama experience significant reductions in fatigue and breathlessness compared to those receiving standard care alone [36] This is largely due to Pranayama 's ability to improve oxygenation and promote relaxation. Radiation therapy, known for causing respiratory issues and heightened anxiety, also benefits from Pranayama . Clinical trials have shown that breast cancer patients practicing Pranayama during radiation therapy exhibited improved lung capacity and reduced anxiety levels [37] This highlights Pranayama 's role in managing the psychological and physical strain of radiation therapy, leading to a more positive treatment experience. In cancer surgery, postoperative recovery often involves pain management and respiratory rehabilitation. Pranayama has been shown to accelerate the recovery of respiratory function and improve pain management. The controlled breathing techniques promote relaxation, aiding in pain reduction and faster healing. Synergistic Effects on Treatment Outcomes and Symptom Management Pranayama 's integration into multimodal cancer care produces synergistic effects that enhance treatment outcomes and symptom management. By improving physiological functions and reducing stress, Pranayama can amplify the effectiveness of conventional treatments. Research suggests that Pranayama may improve oxygen delivery to tissues and reduce oxidative stress, [38] making cancer cells more susceptible to treatment. Additionally,

[Find the meaning and references behind the names: Real]

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 119 Pranayama 's influence on the autonomic nervous system reduces treatment-related anxiety and enhances emotional resilience, which can improve treatment adherence and patient outlook. Tailored Pranayama Practices for Cancer Types and Treatment Phases Customization Based on Cancer Type: Pranayama practices can be customized to address the specific respiratory challenges associated with different cancer types. For lung cancer patients, diaphragmatic breathing and Nadi Shodhana (alternate nostril breathing) are vital for managing breathlessness and enhancing lung capacity. These techniques improve pulmonary function and oxygenation, providing relief from treatment-induced respiratory issues. Breast cancer patients, who may experience anxiety and reduced lung function due to surgery and radiation, can benefit from Bhramari (bee breath). This practice helps alleviate anxiety and supports respiratory recovery by improving parasympathetic tone, aiding in stress management. Stage-Specific Approaches: Pre-Treatment Preparation: Before treatment, Pranayama techniques like Kapalabhati (skull-shining breath) enhance respiratory efficiency and mental focus, preparing patients for the physical and emotional demands of cancer treatments. This preparation strengthens respiratory muscles and improves oxygenation, making upcoming treatments more tolerable. During Active Treatment: During chemotherapy, radiation, or surgery, practices like diaphragmatic breathing help manage side effects such as nausea, fatigue, and breathlessness. Controlled breathing during these phases has been shown to reduce symptom severity and improve patient comfort. Post-Treatment Rehabilitation and Survivorship Care: In the post-treatment phase, Pranayama techniques like Nadi Shodhana aid recovery and support long-term survivorship. These practices restore lung function, reduce fatigue, and enhance emotional resilience, contributing to an improved quality of life during rehabilitation and beyond. Safety, Feasibility, and Practical Guidelines Implementation Considerations: Evaluating the suitability of Pranayama for cancer patients involves assessing their health conditions and identifying any contraindications. Patients with severe respiratory or cardiovascular issues may require modifications or may not be suitable for certain techniques. Starting with gentle methods like diaphragmatic breathing or Nadi Shodhana is generally safe. Healthcare providers should tailor practices to the patient's health status and treatment phase, ensuring sessions are supervised by trained professionals for optimal safety and benefits. Adaptations for Physical Limitations: Pranayama can be adjusted for patients with reduced lung capacity or mobility by shortening sessions or using supported positions like sitting. These adaptations ensure safety and comfort while maintaining consistent practice. Individualized plans that align with patients' abilities and treatment schedules are key to integrating Pranayama effectively into routine care. Future Directions and Research Gaps Emerging Areas for Research: Novel Pranayama protocols tailored to specific cancer challenges are needed. While traditional techniques help with symptoms like breathlessness and anxiety, new approaches could address a broader range of symptoms across various cancer types. Research should also examine the long-term effects of Pranayama on cancer survivorship, including recurrence rates and longevity. Technological Innovations: Telehealth and digital platforms can enhance access to Pranayama , especially for remote patients. These tools offer personalized sessions, real-time feedback, and educational resources. Future studies should evaluate their effectiveness, focusing on patient satisfaction and usability. Remote Monitoring and Feedback: Wearable devices and biosensors provide new ways to monitor Pranayama practice, offering real-time

[Find the meaning and references behind the names: Eissa, Andrea, Toussaint, Gupta, Islam, Soares, Kumar, Majeed, Ann, Nguyen, Samad, Akhter, Swami, Jahan, Pandiyan, Med, Mishra, Begum, Anderson, Ramakrishna]

Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 120 feedback on respiratory patterns and stress markers. Research should validate these tools, explore their integration into cancer care, and assess patient acceptance. Addressing these gaps will enable more personalized and effective Pranayama interventions in cancer care. CONCLUSION Pranayama offers significant benefits for cancer patients, improving respiratory health, enhancing lung capacity, and reducing symptoms like breathlessness. It also positively impacts psychosocial well-being by alleviating anxiety, depression, and stress, improving overall quality of life. Integrating Pranayama into cancer care protocols is recommended, with personalized approaches tailored to each patient's needs and treatment stages. Healthcare practitioners should incorporate these practices into comprehensive care plans, and policymakers should support their inclusion in standard cancer care, leveraging telehealth and digital platforms to increase accessibility and improve patient outcomes. Acknowledgment We want to express our sincere gratitude to Dr. Snehalatha for her invaluable technical support throughout this research. We are also deeply thankful to Ms. Bhairavi Madhusudhan Shibulal, Founder and Director of Solis Health, for providing us with the opportunity and the necessary resources to undertake this work. Your support has been instrumental in the successful completion of this review paper. REFERENCES 1 Swami Muktibodhananda. Hatha Yoga Pradipika: Light on Hatha Yoga. Yoga Publications Trust, Munger, Bihar; 2012. 2 Giridharan S, Pandiyan B, Kumar N V, Soumian S. Effects of Pranayama on Cancer Patients: A Narrative Review of Clinical Outcomes. Cureus [Internet] 2024 [cited 2024 Sep 4];16(2). Available from: /pmc/articles/PMC 10960562/ 3 Majeed H, Gupta V. Adverse Effects of Radiation Therapy. StatPearls [Internet] 2023 [cited 2024 Sep 4]; Available from: https://www.ncbi.nlm.nih.gov/books/NBK 563259/ 4 Li L, Mok H, Jhaveri P, Bonnen MD, Sikora AG, Eissa NT, et al. Anticancer therapy and lung injury: molecular mechanisms. Expert Rev Anticancer Ther [Internet] 2018 [cited 2024 Sep 4];18(10):1041. Available from: /pmc/articles/PMC 6290681/ 5 Papadopoulou A, Govina O, Tsatsou I, Mantzorou M, Mantoudi A, Tsiou C, et al. Quality of life, distress, anxiety and depression of ambulatory cancer patients receiving chemotherapy. Med Pharm Rep [Internet] 2022 [cited 2024 Sep 4];95(4):418. Available from: /pmc/articles/PMC 9694751/ 6 Jayawardena R, Ranasinghe P, Ranawaka H, Gamage N, Dissanayake D, Misra A. Exploring the Therapeutic Benefits of Pranayama (Yogic Breathing): A Systematic Review. Int J Yoga [Internet] 2020 [cited 2024 Sep 4];13(2):99. Available from: /pmc/articles/PMC 7336946/ 7 Campanelli S, Tort ABL, Lobão-Soares B. Pranayamas and Their Neurophysiological Effects. Int J Yoga [Internet] 2020 [cited 2024 Sep 4];13(3):183. Available from: /pmc/articles/PMC 7735501/ 8 Agarwal RP, Maroko-Afek A. Yoga into Cancer Care: A Review of the Evidence-based Research. Int J Yoga [Internet] 2018 [cited 2024 Sep 4];11(1):3. Available from: /pmc/articles/PMC 5769195/ 9 Sengupta P. Health Impacts of Yoga and Pranayama : A Stateof-the-Art Review. Int J Prev Med [Internet] 2012 [cited 2024 Sep 4];3(7):444. Available from: /pmc/articles/PMC 3415184/ 10 Hamasaki H. Effects of Diaphragmatic Breathing on Health: A Narrative Review. Medicines [Internet] 2020 [cited 2024 Sep 4];7(10):65. Available from: /pmc/articles/PMC 7602530/ 11 Swami Prabhavananda. Patanjali Yoga Sutras. Chennai: Ramakrishna Math, Chennai; 2008. 12 Bentley TGK, D’Andrea -Penna G, Rakic M, Arce N, LaFaille M, Berman R, et al. Breathing Practices for Stress and Anxiety Reduction: Conceptual Framework of Implementation Guidelines Based on a Systematic Review of the Published Literature. Brain Sci [Internet] 2023 [cited 2024 Sep 4];13(12). Available from: /pmc/articles/PMC 10741869/ 13 Toussaint L, Nguyen QA, Roettger C, Dixon K, Offenbächer M, Kohls N, et al. Effectiveness of Progressive Muscle Relaxation, Deep Breathing, and Guided Imagery in Promoting Psychological and Physiological States of Relaxation. Evid Based Complement Alternat Med [Internet] 2021 [cited 2024 Sep 4];2021. Available from: /pmc/articles/PMC 8272667/ 14 Jahan I, Begum M, Akhter S, Islam MZ, Jahan N, Samad N, et al. Effects of Alternate Nostril Breathing Exercise on Cardiorespiratory Functions in Healthy Young Adults. Ann Afr Med [Internet] 2021 [cited 2024 Sep 4];20(2):69. Available from: /pmc/articles/PMC 8378456/ 15 A C Bhaktivedanta Swami Prabhupada. Bhagavad-Gita As It Is. Bhaktivedanta Book Trust; 1997. 16 Fincham GW, Kartar A, Uthaug M V., Anderson B, Hall L, Nagai Y, et al. High ventilation breathwork practices: An overview of

[Find the meaning and references behind the names: Manjunath, Sharma, Shyam, Yadav, Raghavendra, Patil, Joshi, Warren, Rajak, Vieira, Jain, Rani, Nikhil, Mendes, Wong, Smith, Abdullahi, Marin, Shanmugam, Karthik]

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Anantha Krishna B S. et al. Role of Pranayama in Enhancing Respiratory Health ISSN: 2456-3110 REVIEW ARTICLE September 2024 Journal of Ayurveda and Integrated Medical Sciences | September 2024 | Vol. 9 | Issue 9 122 37 Giridharan S, Pandiyan B, Kumar N V, Soumian S. Effects of Pranayama on Cancer Patients: A Narrative Review of Clinical Outcomes. Cureus [Internet] 2024 [cited 2024 Sep 5];16(2). Available from: /pmc/articles/PMC 10960562/ 38 Li TT, Wang HY, Zhang H, Zhang PP, Zhang MC, Feng HY, et al. Effect of breathing exercises on oxidative stress biomarkers in humans: A systematic review and meta-analysis. Front Med (Lausanne) [Internet] 2023 [cited 2024 Sep 5];10:1121036. Available from: /pmc/articles/PMC 10132211/ ******************************* How to cite this article: Anantha Krishna B S, Ramya S. Breath of Life: The Therapeutic Role of Pranayama in Enhancing Respiratory Health and Quality of Life in Cancer Care. J Ayurveda Integr Med Sci 2024;9:114-122. http://dx.doi.org/10.21760/jaims.9.9.18 Source of Support: Nil, Conflict of Interest: None declared. Copyright © 2024 The Author(s); Published by Maharshi Charaka Ayurveda Organization, Vijayapur (Regd). This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc-sa/4.0), which permits unrestricted use, distribution, and perform the work and make derivative works based on it only for non-commercial purposes, provided the original work is properly cited

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