Preparation of Visarpahar Taila by Patalyantra Method and...

[Full title: Preparation of Visarpahar Taila by Patalyantra Method and Pharmaceutico-Analytical Study of Visarpahar Taila Cream]

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[Find the meaning and references behind the names: Sachin, Long, Kalpana, Sneha, Good]

ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 22 Preparation of Visarpahar Taila by Patalyantra Method and Pharmaceutico-Analytical Study of Visarpahar Taila Cream Gangaprasad R. Asore 1 , Sachin S. Sheth 2 , Prajakta D. Pansare 3 1 HOD & Associate Professor, Dept. of Rasashastra and Bhaishajya Kalpana, APM’s Ayurved Mahavidyalaya, Sion, Mumbai, Maharashtra, India. 2 Assistant Professor, Dept. of Rasashastra and Bhaishajya Kalpana, APM’s Ayurved Mahavidyalaya, Sion, Mumbai, Maharashtra, India. 3 Post Graduate Scholar, Dep t. of Rasashastra and Bhaishajya Kalpana, APM’s Ayurved Mahavidyalaya, Sion, Mumbai, Maharashtra, India. I NTRODUCTION Ayurveda is one of the oldest systems of medicine with its root in India which is called the ancient science of life. In Ayurveda, a healthy is described as a condition where the Tridoshas present in the body and mind are in an equilibrium state. Ayurveda is a holistic and Address for correspondence: Dr. Prajakta D. Pansare Post Graduate Scholar, Dept. of Rasashastra and Bhaishajya Kalpana, APM’s Ayurved Mahavidyalaya, Sion, Mumbai, Maharashtra, India. E-mail: prajaktapansare 1795@gmail.com Submission Date: 14/01/2022 Accepted Date: 19/02/2022 Access this article online Quick Response Code Website: www.jaims.in DOI: 10.21760/jaims.7.2.4 integral system of medicine that treats the person as a whole in combination with body, mind and soul giving importance to prevention and maintenance of health along with curing the disease promoting longevity of life. Rasashastra and Bhaishajya Kalpana is the branch of Ayurveda which deals with herbal and herbo-mineral drugs for therapeutic use. Some of these drugs which have unique attributes, these unique attributes needs to be validate and explored using the scientific and technological advances of today's world. Bhaishajya Kalpana explains various methods of processing a drug to make the drug more palatable, rich with potency, pleasing with good odor, colour etc. and long lasting to improve the shelf life of the preparation. It is based on the concept of Panchavidha Kashay Kalpana the five basic forms of formulations. The primary Kalpana: Swaras, Kalka, Kwath, Hima and A B S T R A C T Sneha Kalpana is a group of medicated Taila and Ghrita . Sneha Kalpanas manufactured in ayurvedic pharmaceutics are used extensively for medical as well as cosmetic purpose. Taila Kalpanas are the unique formulations of Ayurvedic treatment comes under Sneha Kalpana. Visarpahar Taila is medicated oil used in Ayurveda for Visarpa Vyadhi . Visarpa is correlated with herpes. It is characterized by supportive epithelial inflammatory condition. Skin is the outermost covering of the body serving as a barrier between the external and internal environment. The aggravation of various Dhatus and Doshas results in skin diseases. More than one fifty skin related diseases are described in ayurvedic texts. Visarpa is a common disease mentioned in ayurvedic texts which spreads in body in various directions Visarpahar Taila has been described in Rasaratna Samucchay to be used in Visarpa Vyadhi . As per modern concept, it is said to be caused by Varicella zoster virus. It manifests Daha (Burning sensation), Jwara (fever), Anunnatshopha (swelling) and Vedana (pain). Visarpahar Tail has been prescribed as it's directly act on skin and its content possesses the properties of Visarpanashak The aim of the present study is to prepare Visarpahar Taila by Patalyantra method and it's conversion into cream. In present article, we are trying to study analytical results of Visarpahar Taila cream Key words: Ayurveda, Visarpahar Taila, Visarpahar Taila Cream, Visarpa, Skin Diseases, Sneha Kalpana.

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Gangaprasad R. Asore et al. Preparation of Visarpahar Taila by Patalyantra Method ISSN: 2456-3110 ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 23 Phanta and the secondary Kalpana; Ksheer Kalpana, Sneha Kalpana . Visarpahar Taila is a formulation mentioned in Rasaratna Samucchay for Visarpa Vyadhi , which affects the skin. In ayurvedic texts many remedies are described for Visarpa. Taila Kalpana are the unique formulations of ayurvedic treatment which are prepared by using oil as base or directly extraction of oil by Patalyantra method. The present study is to prepare Visarpahar Taila and cream, and the physicochemical standards of Visarpahar Taila cream. The drugs used in Visarpahar Taila are Erand Beej, Katutumbi Beej, Nimba Beej, Chakramarda Beej, Ankol Beej, Bakuchi Beej. A IM Preparation of Visarpahar Taila by Patalyantra method and pharmaceutico-analytical study of Visarpahar Taila Cream O BJECTIVE 1 To identify raw materials 2 To authenticate raw materials 3 To study literature of Sneha Kalpana and cream preparation 4 To prepare Visarpahar Taila and Visarpahar Taila cream 5 Analytical study of Visarpahar Taila cream M ATERIALS AND M ETHODS The raw material were collected from the field as when required and subjected to the standardization based on the data provided in Ayurveda pharmacopoeia. A) Raw material The samples were collected under the supervision of our unit head. Table 1: Ingredients of Visarpahar Taila SN Raw Drug Part Used Quantity 1. Erand Seeds 150 gm 2. Katutumbi Seeds 150 gm 3. Nimba Seeds 150 gm 4. Chakramarda Seeds 150 gm 5. Ankol Seeds 150 gm 6. Bakuchi Seeds 150 gm B) Apparatus The apparatus used in this experiment is Patalyantra . It is useful to extract oil from raw material. ▪ Assembling of apparatus - Apparatus for Taila Patana comprises 2 earthen pots, collecting vessel, iron wire mesh, cloths and multani mitti . ▪ Earthen pot - capacity of earthen pot - 5 lit ▪ Collecting vessel Quality - Earthen pot Capacity - 500 ml ▪ Procedure of apparatus Clean and dry seeds were taken. After that, they were filled in an earthen pot and mouth was closed by mesh. Sandhibhandhan (sealing)was made for seven layers with the help of Mritalepita Vastra and allowed for drying. A collecting vessel was placed in an inverted position to cover whole mouth of earthen pot and proper Sandhibandhan (sealing) was done and allowed for complete drying. The whole apparatus was carefully tied with the help of an iron wire in order to keep it firmly and also for the easy handling. C) Preparation of pit A rectangular pit was dug at ground level. A small central pit measuring 5 inch in L×B×H was dug at the bottom of the pit. Initially the central small pit was irrigated with sufficient quantity of water. Then the whole apparatus was placed inverted in such a way that the collecting vessel properly accommodates in central small pit. ▪ Fuel source 1 No. of cow dung cakes around - 50.

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[Find the meaning and references behind the names: Shri, Shree, Brown]

Gangaprasad R. Asore et al. Preparation of Visarpahar Taila by Patalyantra Method ISSN: 2456-3110 ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 24 2 Specification of cow dung cakes Diameter of cow dung cake - 15-18 cm Colour of cow dung cakeblackish grey. Average weight of 1 cow dung cake- 98 gms. Method of preparation of Visarpahar Taila 1) All ingredients of Visarpahar Taila were taken, cleaned properly and dried completely in sunlight. Dried and cleaned ingredients were filled in the earthen pot and the mouth was tied tightly with iron sieve. 2) The receiving vessel was placed in an inverted position to cover the mouth of vessel. The whole apparatus was placed inverted in such a way that the collecting vessel properly accommodates in central small pit. 3) Then the cow dung cakes are arranged and above the apparatus. Cow dung cakes were ignited from the bottom, allowed for complete burning. 4) For burning and self-cooling it took around 2-3 hours. After attaining Swangsheeta (self-cooling), the whole apparatus was taken out from the pit with the help of iron wire which was tied. 5) After removing iron wire, Sandhibandhan (sealing) was removed carefully to detach the collecting vessel from earthen pot. Finally the end product was carefully transferred to clean glass container and sealed. Preparation of Visarpahar Taila cream Visarpahar Taila cream was prepared using Visarpahar Taila according to the procedure mentioned in a textbook of cosmetic formulations. Table 2: Composition of Visarpahar Taila cream SN Raw Drug Quantity Taken 1. Visarpahar Taila 30 ml 2. E. Wax 8 gm 3. Stearic acid 8 gm 4. Glycerin 10 ml 5. Distilled water 60 ml 6. Preservatives 0.5 gm Total 105 gm E-wax, Stearic acid and water are heated to a temperature of about 85-90°c in a container. Preservatives should be dissolved in water before heating of mixture. This is mixture A. Visarpahar Taila is added to glycerine. This is mixture B. Mixture B is added to mixture A then it is mixed thoroughly after cooling mixture A. O BSERVATIONS After continuous stirring of mixture A and mixture B, it starts emulsifying and semisolid consistency cream was obtained. 105 gm of brown coloured Visarpahar Taila cream was obtained Table 3: Observation and results of Visarpahar Taila Date of Starting of VT 22/02/2022 Date of completion 22/02/2022 Fuel Used 50 Cow Dung Cakes Weight of Cow dung cakes 4.7 kg Quantity Taken 900 gms Quantity of VT obtained 35 ml Time taken for the extraction of VT 3 hrs Analytical study of Visarpahar Taila cream In present study, analytical evaluation of Visarpahar Taila cream was carried out. The samples were analysed first of all on the basis of organoleptic characters. Physico-chemical parameters such as rancidity, pH, total acidity, loss on drying and microbial contamination were done at Shree Dhootpapeshwar Ayurvedic Research Foundation, Panvel.

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Gangaprasad R. Asore et al. Preparation of Visarpahar Taila by Patalyantra Method ISSN: 2456-3110 ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 25 Observation and results of Visarpahar Taila cream Table 4: Analytical values of Visarpahar Taila cream SN Test Values 1. Colour Brown 2. Odour Charred 3. Rancidity Complies 4. Total acidity 0.65% 5. pH 6.1 6. Loss On Drying 72.83 7. Spreadability Uniformly Spreadable 8. Appearance Semisolid soft cream Table 5: Microbial Contamination SN Test Values 1. TPC Count 1*10 3 cfu/ml 2. TYMC Count 10 cfu/ml 3. E.Coli Absent 4. P.aeruginosa Absent 5. S.typhi Absent 6. S.aureus Absent DISCUSSION Raw materials procured from authentic source that give optimum result as it reflects in physicochemical analytical studies of raw materials pass the ayurvedic pharmacopoeia standards. An organoleptic study shows that appearance, odor and touch is acceptable to go for further analysis and clinical use. In Visarpahar Taila, Erand Beej, Katutumbi Beej, Nimba Beej, Chakramarda Beej, Ankol Beej, Bakuchi Beej are the main constituents which are Ushnaveeryatmak (Hot in potency ) . By virtue of these properties, it is Kaphavatshamak . So mainly used in Vataj and Kaphaja Visarpa. Visarpahar Taila is unique formulation designed by our Acharyas for the management of symptoms of Visarpa . Visarpa is correlated with herpes, which is characterized by suppurative epithelial inflammatory condition on skin. For which the main line of treatment is explained as external application. If we look deep into the general method of preparation of Visarpahar Taila , it is obtained by extraction method i.e., to extract all the active principles of drugs. The analytical values of Visarpahar Taila cream appearance is semisolid soft cream, colour brown, odour charred, pH of cream is 6.1, spreadability of cream is uniform spreading. The indications of Visarpahar Taila and Visarpahar Taila cream are said to be in the symptomatic management of Visarpa Vyadhi . Clinical study of Visarpahar Taila and Visarpahar Taila cream can be done on patients and is analytically found to be safe for external use. CONCLUSION The formulated cream has the entire expected efficacy which was mentioned in literature of Visarpahar Taila , as the Visarpahar Taila working against Visarpa. Oil plays an important role in preserving the structure of the skin. We need both oils and water in order to hydrate the skin efficiently. So, the aim of the cream preparation is to provide alternative to oil. Analytical parameters show it is safe for external application.

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Gangaprasad R. Asore et al. Preparation of Visarpahar Taila by Patalyantra Method ISSN: 2456-3110 ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 26

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Gangaprasad R. Asore et al. Preparation of Visarpahar Taila by Patalyantra Method ISSN: 2456-3110 ORIGINAL ARTICLE March 2022 Journal of Ayurveda and Integrated Medical Sciences | March 2022 | Vol. 7 | Issue 2 27 REFERENCES 1 Sharangadhara. Sharangadhara Samhita with commentaries by Brahmanand Tripathi, Madhyama Khand 9, Verse 1. Chaukhambha Surbharati Prakashan, Varanasi. Reprint Edition 2001,Pg 218. 2 Priyavrat Sharma. Dhanvantari Nighantu, Amragandhi Varga. Chaukhambha Orientalia, Varanasi. 3 rd edition, 2005, Pg 105. 3 Indradev Tripathi, Acharya Vishwanath Dwivedi. Raj Nighantu Commentory (Hindi) Prabhadradi Varga. Chaukhambha Krishnadas Academy, Varanasi. Reprint edition 2010, Pg 264. 4 Priyavrat Sharma. Dhanvantari Nighantu, Amragandhi Varga. Chaukhambha Orientalia, Varanasi. 3 rd edition, 2005,Pg 58. 5 Priyavrat Sharma. Dhanvantari Nighantu, Amragandhi Varga. Chaukhambha Orientalia, Varanasi. 3 rd edition, 2005,Pg 776. 6 Tripathi B. Sharangdhar Samhita, Ghrut Taila Kalpana, Madhyam Khanda, chapter 9, Verse 1-2. Varanasi; Chaukhamba Surbharti Prakashan. reprint ed, 2017,Pg 144. 7 Indradev Tripathi, Acharya Vishwanath Dwivedi. Raj Nighantu Commentory (Hindi), Shatavhadi Varga. Chaukhambha Krishnadas Academy, Varanasi. Reprint edition 2010, Pg 102. 8 Indradev Tripathi, Acharya Vishwanath Dwivedi. Raj Nighantu Commentory (Hindi), Dharanyadi Varga. Chaukhambha Krishnadas Academy, Varanasi. Reprint edition 2010, Pg 39. 9 Indradev Tripathi. Rasaratna Samucchay, Visarpakushthashwitra Chikitsa Adhyay. Chaukhambha Academy, Varanasi. 3 rd Edition 2006, Shlok 4-5,Pg 243. 10 Sachin S Sheth, Gangaprasad R Asore, Kiran Sudhakar Darade. Pharmaceutico-Analytical study of Karanjadi Taila and its conversion into cream. J Ayurveda Integr Med Sci. 2020;5:245- 249. 11 Indradev Tripathi. Rasaratnasamucchay. Chaukhambha Academy, Varanasi. 3 rd Edition 2006, Yantranirupanam Adhyaya, Pg 98. 12 Pandit Kashinatha Shastri. Rasatarangini, Yantravidnyaniya Chaturtha Tarang. Motilal Banarasidas, Varanasi. 8 th Edition 2014, Shlok no 47-52,Pg 56. 13 Gaurav Kumar. Text book of cosmetic formulations. May 2018. Page No 57. 14 Anonymous. Ayurvedic Pharmacopoeia of India, Part 1, volume VII, Appendix 2,3, Government of India, Ministry of Health and family welfare, Department of AYUSH. 2007, Page No 243, 213, 290, 300, 299, 298, 290, 291, 301. How to cite this article: Gangaprasad R. Asore, Sachin S. Sheth, Prajakta D. Pansare. Preparation of Visarpahar Taila by Patalyantra Method and Pharmaceutico- Analytical Study of Visarpahar Taila Cream. J Ayurveda Integr Med Sci 2022;2:22-27. http://dx.doi.org/10.21760/jaims.7.2.4 Source of Support: Nil, Conflict of Interest: None declared.

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Ayurveda, Visarpa, Ph, Tailakalpana, Burning sensation, Sandhibandhan, Active principle, Time taken, Skin disease, Earthen pot, Analytical study, External application, Brown colour, Loss on drying, Microbial Contamination, Sneha Kalpana, Organoleptic character, Raw material, Raw drug, Total acidity, Self-cooling, Distilled water, Glycerin, Preservative, Stearic acid, Cow dung cake, Herpes.