A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method of...

[Full title: A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method of preparation]

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REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 196 A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method of preparation Dr. Pooja Krishna Prasad 1 , Dr. Sangeeta Rao 2 , Dr. Vikram S 3 1 Post Graduate Scholar, 2 Associate Professor, 3 Professor and HOD, Department of Rasa Shastra and Bhaishajya Kalpana, Sri Sri College of Ayurvedic Science and Research, Bangalore, Karnataka, INDIA. I NTRODUCTION Rasashastra is a branch of Ayurveda which mainly deals with the usage of metals, minerals in therapeutics. It mainly has importance in Lohavada i.e., converting lower metals to higher metals and Dehavada i.e., therapeutics. It is said that Rasoushadhis have immediate action on the desired site with very minimal dosage. Murcchana is one of the important Adharabhuta Siddhanta of Rasashastra , wherein it increases the therapeutic efficacy of Parada . It makes Parada safe for ingestion. During the bygone age, people had to move from one Address for correspondence: Dr. Pooja Krishna Prasad Post Graduate Scholar, Department of Rasa Shastra and Bhaishajya Kalpana, Sri Sri College of Ayurvedic Science and Research, Bangalore, Karnataka, INDIA. E-mail: vaidyapoojaprasad@gmail.com Submission Date: 15/09/2019 Accepted Date: 24/10/2019 Access this article online Quick Response Code Website: www.jaims.in Published by Maharshi Charaka Ayurveda Organization, Vijayapur, Karnataka (Regd) under the license CCby-NC-SA place to another due to which there was difficulty in carrying medicines or to prepare medicines on the run, there by giving a way for Pottali Kalpana to come into existence in which the drugs were made into compact form, rubbed with a media and administered. Pottali Kalpana is one among the Moorchita Parada Yogas. When people had to travel long distances where there was inadequate availability of emergency medicines, Pottali Kalpana played an important role as it is administered sublingually and has fast absorption. May be, this was one of the reasons for the growth of Pottali Kalpana as it gives compactness to the medicines and also increases its bioavailability. During the travel, it was difficult to carry Kupi or any pots with medicines as it was more prone to damage and there is loss of the medicine, Pottali due to its compactness is easy for transportation [1] Historical Review The first reference of Pottali Kalpana can be found in the text Rasa Ratnakara of 12 th century where in Putapaka method of preparation was explained in the context of Ratnagarbha Pottali and Shankhagarbha Pottali Rasa [2] First reference for Kaparda Purana and Putapaka can be found in the text Rasendra Sara A B S T R A C T Pottali Kalpana is one of the unique Kalpana mentioned in our classics. It is one among the four Moorchita Parada Yogas. Kaparda Purana Putapaka method is one the methods mentioned for preparation of this Kalpana . It brings in the compactness of the Dravyas . Pottali Kalpana are a blend of extremely important trace elements which form the crux of the immune system. Various Kaparda Purana Method of preparation of Pottalis have been compiled here which have been mentioned in classical Rasashastra texts along with its ingredients and other variations. The alkalinity of the Kaparda Purana method of preparation owing to calcium probably has a significant role to play in the management of Atisara and Grahani . This Kalpana can be used in emergency care as well. Key words: Moorchita Parada Yogas, Putapaka, Pottali Kalpana.

[Find the meaning and references behind the names: Khalwi, Rana]

Dr. Pooja Krishna Prasad et al. A Rev ISSN: 2456-3110 Journal of Ayurveda and Integr Sangraha and Rasa Prakasha Sudhak century [3] Gandhaka Drava Paka preparation was first found in the text Ra Sudhakara of 13 th century [4] Pottali pr Bhavana Vidhi was first found in the te Sara Sangraha of 13 th century [5] M ATERIALS AND M ETHODS Pottali Kalpana can be defined as giving to scattered material. It is one of preparations of Rasashastra with an compactness of materials, conv preservation, easy transportation and hig at minimal doses. िव ा रत व ुनो अ ीभावानाम् पो म्। पो ्ला इित गृ ाित इित पो िल॥ [6] Most of the Pottalis are Sagandha Sagn of Parada . Some of them include Niragn preparation by giving Bhavana . Rasaka classified into 4 types based on their preparation as: Khalwi Rasayana, Rasayana, Pottali Kalpana, Parpati Kalp these, Pottali Kalpas are rarely used by t due to its elaborate method of prepa Kalpana is prepared by giving intense am so the bond of Pottali Kalpana may be than Kajjali or Parpati Kalpana . Hence, absorbed instantly at smaller doses. Potta mainly prepared by 3 methods. Review on Pottali Kalpana w.s.r. to Kaparda Pur REVIEW ARTI tegrated Medical Sciences | Sept - Oct 2019 | Vol. 4 hakara of 13 th method of Rasa Prakasha prepared from e text Rasendra ing compactness of the unique an insight of onvenient for highly effective agni Murcchana ragni method of sakalpas can be heir method of na, Kupipakwa Kalpana. Among by the clinicians reparation. This amount of heat, be more potent ce, it might get ottali Kalpana is Putapaka Vidhi: Putapaka procedures of Rasashastra subjected to intense h nanoparticles. In this me triturated in prescribed Subhavita Lakshanas . It is dried, placed in Musha or is done and subjected to be in the form of Bhasma is extensively found under t Kaparda/Shankha Purana ingredients are triturated later filled in Shodita Kap Lepana to the Mukha of Ka It is then placed in Sharava Gandhaka Drava Paka: ingredients are triturated made into Shikarakara or drying, it is wrapped in a suspended in a vessel con which is in turn placed in a given. The Gandhaka starts The quantity of Gandhak throughout the procedure the attainment of Siddha silk cloth, Vyoma Varna of S Bhavana Vidhi: In this me triturated with specified Yantra till the attainment Later, this is rolled into pill and stored. This method i Khalwi Rasayana . Various references of Ka Pottali Kalpana Text Pottali Ingredi Rasendra Sara Sangraha Lokanath a Rasa [7] Rasa Si Shuddh Gandha Purana Putapaka method RTICLE Sept-Oct 2019 ol. 4 | Issue 5 197 paka is one of the important astra where in the drugs are heat and converted into method, the ingredients are ed media till attainment of It is then made into Chakrikas , or Sharava . Sandhi Bhandana to Puta . The final product will a . This method of preparation der the heading Pottali . rana: In this method, the ted with prescribed media and Kaparda or Shodita Shankha. Kaparda or Shankha is done. ava and subjected to Puta . aka: In this method, the ted with prescribed media and or Puga Phala Sadrusha. After in a silk cloth. This Pottali is l containing molten Gandhaka in a Valuka Yantra and Agni is tarts liquifying and Paka begins. dhaka should be maintained ure. It should be carried out till dha Lakshanas like burning of of Sulphur, Metallic sound. s method, the ingredients are ied liquid media in a Khalwa ent of Subhavita Lakshanas . pills of prescribed dose, dried od is similar to preparation of Kaparda Purana Putapaka redients Kapard a Lepana Puta sa Sindoora – 1 p uddha ndhaka – 4 p Tankan a Gaja Puta

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 198 Rajamrug anka Rasa [8] Rasa Sindoora – 3 p Swarna Bhasma – 1 p Rajata Bhasma – 1 p Shuddha Silajatu – 2 p Shuddha Gandhaka – 2 p Shuddha Haratala – 2 p Tankan a + Ajakshe era Gaja Puta Lokeshw ara Pottali Rasa [9] Rasa Sindoora – 1 p Swarna Bhasma – 1/4 th P Shuddha Gandhaka – 2 p Tankan a Gaja Puta Ratnagar bha Pottali Rasa [10] Vajra Bhasma - 1 p Swarna Bhasma - 1 p Rajata Bhasma - 1 p Naga Bhasma - 1 p Loha Bhasma - 1 p Tamra Bhasma - 1 p Shuddha Mukta - 1 p Shuddha Vidruma - 1 p Tankan a + Arka Dugda Gajapu ta Hemagar bha Pottali Rasa [11] Shuddha Makshika - 1 p Shankha Bhasma - 1 p Shuddha Tutta - 1 p Rasa Sindoora – 3 P Swarna Bhasma – 1 p Tamra Bhasma – 1 p Shuddha Gandhaka – 1 p Tankan a Gajapu ta Rasa Prakasha Sudhakara Hemagar bha Pottali Shuddha Parada – 4 Tola Shuddha Swarna – Tankan a + Naga Gajapu ta Rasa 1 [12] 1 Tola Shuddha Gandhaka – 6¼ Tola Bhasma + Snuhi Dugdha Lokanath a Rasa [13] Shuddha Parada – 2 p Shuddha Gandhaka – 2 p Shuddha Kaparda – 8 p Tankana – 1 p Shankha Bhasma – 8 p Tankan a + Arka Dugda Gajapu ta Rajamrug anka Rasa [14] Shuddha Parada – 3 p Swarna Bhasma – 1 p Abhraka Bhasma – 1 p Shuddha Manashila – 2 p Shuddha Gandhaka – 2 p Shuddha Haratala – 2 p Tankan a + Ajadugd a Varaha Puta Rasa Ratna Samuccha ya Rajamrug anka Rasa [15] Rasa Bhasma – 3 p Swarna Bhasma – 1 p Tamra Bhasma – 1 p Shuddha Manashila – 2 p Shuddha Gandhaka – 2 p Shuddha Haratala – 2 p Tankan a + Aja Ksheera Gaja Puta Shankesh wara Rasa [16] Shankha Bhasma – 1 Niska Kaparda Bhasma – 4 Niska Shuddha Tutta - ½ Niska Shuddha Gandhaka - 5½ Tankan a + Aja Ksheera Gaja Puta

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 199 Niska Shuddha Naga - 5½ Niska Rasa Sindoora - 5½ Niska Shuddha Tankana – 5½ Niska Hemagar bha Pottali Rasa [17] Parada Bhasma – 2 Niska Swarna Bhasma – 1 Niska Tankan a + Aja Ksheera Gaja Puta Lokanath a Rasa [18] Rasa Bhasma – 1 p Swarna Bhasma - ¼ P Tankan a + Dugdha Varaha Puta Laghu Lokeshw ara Rasa [19] Shuddha Gandhaka – 2 p Shuddha Parada – 1 p Shuddha Gandhaka – 4 p Tankan a + Dugdha Laghu Puta Rasa Chintaman i Kanchan a Pottali Rasa [20] Shuddha Swarna Patra – 480 Ratti Shuddha Swarnamakshika – 480 Ratti Shuddha Parada – 240 Ratti Shuddha Gandhaka – 240 Ratti Shuddha Kaparda Wheat Flour + Water Varaha Puta Lokesha Pottali Rasa [21] Shuddha Gandhaka – 480 Ratti Shuddha Parada – 480 Ratti Shankha Bhasma – 480 Ratti Kapota Puta Laghu Pottali Rasa [22] Shuddha Gandhaka – 2 Tola Shuddha Parada – 2 Tola Sveta Abhraka Bhasma – 2 Tola Shuddha Kaparda Dagdha shma Churna Gaja Puta Saranghad hara Samhita Lokanath a Rasa [23] Shuddha Parada – 2 p Shuddha Gandhaka – 2 p Shuddha Kaparda – 8 p Shuddha Shankha – 8 p Tankan a + Godugd ha Tankan a – 1/8 P Gaja Puta Hemagar bha Pottali Rasa 1 [24] Shuddha Parada – 1 p Swarna Bhasma - ¼ P Shuddha Gandhaka – 2 p Vatsana bha – 1/16 p with Snuhi Ksheera Gaja Puta Rasa Manjari Ratnagar bha Pottali Rasa [25] Rasa Bhasma -1 p Vajra Bhasma -1 p Swarna Bhasma - 1 p Roupya Bhasma - 1 p Loha Bhasma -1 p Tamra Bhasma -1 p Mukta Bhasma -1 p Makshka Bhasma - 1 p Vidruma Bhasma - 1 p Shankha Bhasma - 1 p Tankan a + Arka Dugdha Gajapu ta Lokeshw ara Pottali Rasa [26] Rasa Bhasma – 1 p Swarna Bhasma - ¼P Shuddha Gandhaka – 2 p Tankan a Gajapu ta

[Find the meaning and references behind the names: Pala, Kumari]

Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 200 Rajamrug anka Rasa [27] Rasa Bhasma – 3 p Swarna Bhasma – 1 p Tamra Bhasma – 1 p Shuddha Shilajatu – 2 p Shuddha Gandhaka – 2 p Shuddha Haratala – 2 p Tankan a + Aja Ksheera Gajapu ta Rasa Kamadhen u Lokanaya ka Rasa [28] Shuddha Parada – 5 Karsha Shuddha Gandhaka – 7½ Karsha Arka Dugdha + Kumari Rasa Bhavita Tankan a Laghup uta Lokeshw ara Rasa [29] Rasa Bhasma – 1 p Swarna Bhasma - ¼ P Shuddha Gandhaka – 2 p Tankan a Varaha puta Ratnagar bha Pottali Rasa [30] Parada Bhasma – 1 p Vajra Bhasma – 1 p Swarna Bhasma – 1 p Rajata Bhasma – 1 p Naga Bhasma – 1 p Loha Bhasma – 1 p Tamra Bhasma – 1 p Maricha – 7 p Mukta Bhasma – 1 p Vidruma Bhasma – 1 p Makshika Bhasma – 1 p Shankha Bhasma – 1 p Tankan a + Arka Dugdha Gajapu ta Tuttha Bhasma – 1 p Hiranyag arbha Pottaliras a [31] Parada Bhasma – 1 Pala Swarna Bhasma – 1 Karsha Shuddha Gandhaka – 2 Pala Tankana – 1 Masha Tankan a + Snuhi Ksheera Gajapu ta Hemagar bha Pottali Rasa [32] Shuddha Parada – 1 p Shuddha Swarna – 1/4 p Shuddha Gandhaka – 2 p Tankan a Gajapu ta Lokeshw ara Pottali Rasa [33] Parada Bhasma – 1 p Swarna Bhasma – 1/4 p Shuddha Gandhaka – 2 p Tankan a+Godu gda Gajapu ta Lokanath a Rasa [34] Shuddha Parada – 2 p Shuddha Gandhaka – 2 p Gajapu ta Yoga Ratnakara Ratnagar bha Pottali Rasa [35] Rasa Bhasma -1 p Vajra Bhasma -1 p Swarna Bhasma - 1 p Roupya Bhasma - 1 p Naga Bhasma -1 p Loha Bhasma -1 p Abhraka Bhasma - 1 p Shankha Bhasma - 1 p Mukta Bhasma -1 p Makshika Bhasma - 1 p Vidruma Bhasma - 1 p Tankan a + Arka Dugdha Gajapu ta

Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 201 Rajavarta -1 p Vaikranta -1 p Gomeda -1 p Pushparaga -1 p Rajamrug anka Rasa [36] Rasa Bhasma – 3 p Swarna Bhasma – 1 p Tamra Bhasma – 1 p Shuddha Shilajatu – 2 p Shuddha Haratala – 2 p Shuddha Gandhaka – 2 p Tankan a + Aja Ksheera Gajapu ta Lokeshw ara Pottali Rasa [37] Rasa Bhasma – 1 p Swarna Bhasma - ¼P Shuddha Gandhaka – 2 p Tankan a Varaha Puta Bhaishajya Ratnavali Ratnagar bha Pottali Rasa [38] Shuddha Parada -1 Tola Heeraka Bhasma -1 Tola Swarna Bhasma -1 Tola Rajata Bhasma -1 Tola Loha Bhasma -1 Tola Tamra Bhasma -1 Tola Tankan a + Arka Dugdha Gajapu ta Hemagar bha Pottali Rasa [39] Rasa Sindoora – 3 Tola Swarna Bhasma – 1 Tola Tamra Bhasma – 1 Tola Shuddha Gandhaka – 1 Tola Tankan a + Jala Gajapu ta Lokeshw ara Pottali Rasa Sindoora – 4 p Swarna Bhasma – Tankan a Gajapu ta Rasa [40] 1 p Shuddha Gandhaka – 8 p Rajamrug anka Rasa [41] Rasa Bhasma – 3 p Swarna Bhasma – 1 p Tamra Bhasma – 1 p Shuddha Manashila – 2 p Shuddha Haratala – 2 p Tankan a + Aja Ksheera Gajapu ta Lokanath a Rasa [42] Shuddha Gandhaka – 2 p Parada Bhasma – 1 p Shuddha Gandhaka – 4 p Tankan a Gajapu ta Yoga Tarangini Ratnagar bha Pottali Rasa [43] Parada Bhasma Vajra Bhasma Swarna Bhasma Rajata Bhasma Naga Bhasma Loha Bhasma Tamra Bhasma Mukta Bhasma Swarnamakshika Bhasma Vidruma Rajavarta Vaikranta Gomeda Pushparaga Sankha Bhasma Tankan a + Arka Ksheera Gajapu ta Rajmruga nka Rasa [44] Parada Bhasma - 3 p Swarna Bhasma - 1 p Tamra Bhasma - 1 p Shuddha Manahshila - 2 p Shuddha Haratala - 2 p Shuddha Tankan a + Aja Dugdha Gajapu ta

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 202 Gandhaka - 2 p Rasayanas ara Lokanath a Rasa [45] Shuddha Parada – 1 p Shuddha Gandhaka - ½P Tankan a + Gomutr a Gaja Puta Rajamrug anka Rasa [46] Rasa Sindoora – 3 Tola Swarna Bhasma – 1 Tola Rajata Bhasma – 1 Tola Shuddha Manashila – 2 Tola Shuddha Haratala – 2 Tola Shuddha Gandhaka – 2 Tola Tankan a + Aja Ksheera Gaja Puta Hemagar bha Pottali Rasa [47] Rasa Sindoora – 1 Tola Swarna Bhasma – 3 Masha Mukta Bhasma – 3 Masha Shuddha Gandhaka – 3 Masha Tamra Bhasma – 1 Tola Naga Bhasma – 1 Tola Vanga Bhasma – 1 Tola Tankan a + Mandar apayasa Gaja Puta Various Dosage Mentioned Most of the Acharyas have mentioned the dose of Pottali Kalpana as 2 Ratti and 4 Ratti . Acharya Yashodara in the text Rasa Prakasha Sudhakara has mentioned the dose as 1 Ratti for Rajamruganka Rasa , 2 Ratti for Hemagarbha Pottali Rasa and 4 Ratti for Lokanatha Rasa. Acharya Anantadev Suri in the text Rasa Chintamani has mentioned the dose as 12 Ratti for Kanchana Pottali Rasa , Lokesha Pottali Rasa and 6 Ratti for Laghu Pottali Rasa . Rasa Vagbhata in the text Rasa Ratna Samucchaya has mentioned the dose as 1 Ratti for Mruganka Pottali Rasa . Acharya Sharangadhara has mentioned the dose as 1 Ratti for Hemagarbha Pottali Rasa and 6 Ratti for Lokanatha Rasa . Acharya Chudamani in the text Rasa Kamadhenu has mentioned the dose as 6 Ratti for Lokanayaka Rasa . Acharya Govind Das in the text Bhaishajya Ratnavali has mentioned the dose as 1 Ratti for Ratnagarbha Pottali Rasa and Hemagarbha Pottali Rasa . Acharya Trimalla Bhatta in the text Yoga Tarangini has mentioned the dose as 5 Ratti for Rajamruganka Rasa . Various Anupana mentioned Most of the Acharyas have mentioned Madhu or Pippali Churna with Madhu or Maricha Churna with Ghrita . Acharya Yashodara in the text Rasa Prakasha Sudhakara has mentioned Guduchi Rasa + Jala or Guda + Ardraka Rasa for Hemagarbha Pottali Rasa . Acharya Anantadev Suri in the text Rasa Chintamani has mentioned Ushnodaka or Sheetodaka for Kanchana Pottali Rasa . Acharya Sharangadhara has mentioned Maricha + Ghrita in Vatatisara, Navaneeta in Pittatisara , Madhu in Kaphatisara for Lokanatha Rasa . Shyamasundaracharya in the text Rasayana Sara has mentioned Sitopaladi Churna for Rajamruganka Rasa . Various Indications mentioned Most of the Pottalis have been described in the context of Kshaya or Atisara or Grahani Roga.

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 203 Apart from these diseases, it can also be administered in Kasa, Shwasa, Mandagni, Jwara, Prameha etc. Acharya Yashodara in the text Rasa Prakasha Sudhakara has indicated Hemagarbha Pottali Rasa for Kasa, Shwasa, Agnimandya etc. Acharya Anantadev Suri in the text Rasa Chintamani has indicated Kanchana Pottali Rasa for Kusta , Mandagni, Atisara etc. Lokesha Pottali Rasa for Jwara, Sangrahani and Laghu Pottali Rasa for Prameha, Vatavyadhi, Mandagni, Jwara etc. Rasa Vagbhata in the text Rasa Ratna Samucchaya has indicated Lokanatha Rasa for Kasa, Hikka, Mandagni etc. and Laghu Lokeshwara Rasa for Mutrakricchra . Acharya Sharangadhara has indicated Lokanatha Rasa for Kasa, Shwasa, Gulma, Mandagni etc. and Hemagarbha Pottali Rasa for Kasa, Shwasa, Aruchi etc. In the text Rasa Manjari , Acharya has indicated Lokeshwara Pottali Rasa for Kasa , Pittavikara etc. Acharya Chudamani in the text Rasa Kamadhenu has indicated Lokanayaka Rasa for Kasa, Sula, Shotha, Mandagni etc. In the text Yoga Ratnakara, Rajamruganka Rasa is indicated for Kasa, Shwasa, Pandu etc. and Lokeshwara Pottali Rasa for Jwara, Bhrama, Mada, Unmada etc. Acharya Govind Das in the text Bhaishajya Ratnavali has indicated Ratnagarbha Pottali Rasa for Ashmari, Vatavyadhi, Kusta, Prameha, Udararoga, Arsha, Shwasa, Kasa, Jwara etc. and Lokeshwara Pottali Rasa for Kasa, Pandu, Jwara etc. DISCUSSION Pottali Kalpana is one of the unique Kalpana in Rasashastra . It is enlisted among the four Moorchita Parada Yogas . It has a distinctive and elaborate method of preparation. This Pottali Kalpana is known for its quicker action in minimal dosage and compactness in the drug. Among the various methods of preparation of Pottalis, Kaparda Purana followed by Putapaka is one which is unique in its own way. When we go through the historical background of Pottali Kalpana , it is clear that Putapaka method of preparation was the first method that was introduced in 12 th century. Later in 13 th century, Gandhaka Drava Paka and Kaparda/Shankha Purana methods came into existence. Compactness, is one of the important points which has been concentrated while formulating these Pottali Yogas . Compactness, not only in its physical appearance but also the structure of each molecule was considered. Probably, this is the reason behind placing Putapaka , Bhavana Vidhi and Kaparda/Shankha Purana methods under the heading of Pottali Kalpana . In the classics, various Pottali Kalpanas in various texts of Rasashastra is available. Most of them fall under the category of Putapaka method of preparation. Among them 41 Yogas are of Kaparda Purana Putapaka method of preparation. In this particular method, the Shodhita drugs are given Bhavana with prescribed Drava Dravya, later the mixture is filled into Shodhita Kapardas , sealed and subjected to Putapaka . Sealing of the open slit of Kaparda is done to avoid the spillage of the material filled inside. The drugs usually mentioned for sealing is Tankana alone or along with Godugdha/Ajaksheera/Arkaksheera . There are few references which also mention the application of Sudha Churna over the Sharavas . This might contribute in enhancing the calcium content to some extent and thus there will be a proportionate increase in Kshara Guna /alkalinity, hence enhancing the efficacy of the formulation. Most of the Yogas have been mentioned to be subjected to Gajaputa , whereas few of them have been mentioned to give Laghu Puta or Varaha Puta as well. The variation in this is because of the fact that some require lesser heat while others require more. Usual dosage for each Pottali Kalpana is between 2 Ratti - 4 Ratti i.e, 250 mg- 500 mg, which is a very minimal dosage. Most of these Yogas are mentioned under the Kshaya

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 204 Roghadhikara, Atisara Rogadhikara, or Grahani Roghadhikara. The alkalinity of the formulation owing to calcium probably has a significant role to play in the management of Atisara and Grahani . But it's significance in Kshaya Roga doesn't seem to fit the bill. But on a deeper observation, these Pottali Kalpana are a blend of extremely important trace elements which form the crux of the immune system, and hence they help by strengthening it. Also recent studies [48] suggest that calcium plays a very important role in treatment of Kshaya by reducing a specific type of calcium channel activity and hence causing calcium influx, and thus fighting against mycobacterium tuberculosis, the causative agent in Kshaya . It is also indicated in Kasa and Shvasa . CONCLUSION Pottali Kalpana is one among the 4 Moorchita Parada Yogas. It is known for its compactness attained not only structurally but also in the molecular level. The use of Kaparda Purana Putapaka method of preparation of Pottali Kalpana has been mentioned to be effective in disorders of Gastro – Intestinal tract. It has also been mentioned to be effective in Kshaya Roga . Not much Yogas are available in the market. Further toxicological and clinical study should be carried out and this formulations need to be brought into the market for the benefit of the society. REFERENCES 1 Dwivedi Vasudevmulashankar. Parada Vigyana.Datia: Shri Sharma Ayurveda Mandir;1997:p 168. 2 Dwivedi Vasudevmulashankar. Parada Vigyana.Datia: Shri Sharma Ayurveda Mandir;1997:p 168. 3 Mishra Siddhinandan. Rasa Prakasha Sudhakara of Acharya Yashodara with Sidhiprada Hindi commentary.Varanasi:Chowkhamba Orientalia;2009:p 159. 4 Mishra Siddhinandan. Rasa Prakasha Sudhakara of Acharya Yashodara with Sidhiprada Hindi commentary. Varanasi:Chowkhamba Orientalia;2009:p 139. 5 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha “Rasavidyotini” Hindi commentary. Varanasi: Chowkhamba Orientalia;2010:p 205. 6 Dwivedi Vasudevmulashankar. Parada Vigyana.Datia: Shri Sharma Ayurveda Mandir;1997:p 168. 7 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha Rasavidyotini Hindi commentary. Varanasi: Chowkhamba Orientalia;2010:p 185. 8 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha Rasavidyotini Hindi commentary. Varanasi: Chowkhamba Orientalia;2010:p 267. 9 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha, Rasavidyotini Hindi commentary. Varanasi: Chowkhamba Orientalia;2010:p 269. 10 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha, Rasavidyotini, Hindi commentary. Varanasi: Chowkhamba Orientalia;2010:p 268. 11 Mishra Siddhinandan. Rasendra Sara Sangraha with Savimarsha Rasavidyotini Hindi commentary.Varanasi: Chowkhamba Orientalia;2010:p 272. 12 Mishra Siddhinandan. Rasa Prakasha Sudhakara of Acharya Yashodara with Sidhiprada Hindi commentary. Varanasi: Chowkhamba Orientalia;2009:p 159. 13 Mishra Siddhinandan. Rasa Prakasha Sudhakara of Acharya Yashodara with Sidhiprada Hindi commentary. Varanasi: Chowkhamba Orientalia;2009:p 162. 14 Mishra Siddhinandan. Rasa Prakasha Sudhakara of Acharya Yashodara with Sidhiprada Hindi commentary. Varanasi: Chowkhamba Orientalia;2009:p 162. 15 TripathiIndra Dev(ed). Rasa Ratna Samucchaya of Vagbhatacharya with Rasprabha Hindi commentary. ED/2 nd. Varanasi: Chowkhamba Sanskrit Bhavan; 2003:p 159. 16 TripathiIndra Dev(ed). Rasa Ratna Samucchaya of Vagbhatacharya with Rasprabha Hindi commentary. ED/2 nd. Varanasi: Chowkhamba Sanskrit Bhavan; 2003:p 159. 17 TripathiIndra Dev(ed). Rasa Ratna Samucchaya of Vagbhatacharya with Rasprabha Hindi commentary. ED/2 nd. Varanasi: Chowkhamba Sanskrit Bhavan; 2003:p 160. 18 TripathiIndra Dev(ed). Rasa Ratna Samucchaya of Vagbhatacharya with Rasprabha Hindi commentary. ED/2 nd. Varanasi: Chowkhamba Sanskrit Bhavan; 2003:p 161. 19 TripathiIndra Dev(ed). Rasa Ratna Samucchaya of Vagbhatacharya with Rasprabha Hindi commentary.

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 205 ED/2 nd. Varanasi: Chowkhamba Sanskrit Bhavan; 2003:p 198. 20 Mishra Siddhinandan. Rasa Chintamani of Acharya Anantadev Soori with Siddhiprada Hindi commentary. ED 2 nd. Varanasi: Choukhambha Publishers; 2003:p 157. 21 Mishra Siddhinandan. Rasa Chintamani of Acharya Anantadev Soori with Siddhiprada Hindi commentary. ED/2 nd. Varanasi: Choukhambha Publishers; 2003:p 159. 22 Mishra Siddhinandan. Rasa Chintamani of Acharya Anantadev Soori with Siddhiprada Hindi commentary. ED/2 nd. Varanasi: Choukhambha Publishers; 2003:p 163. 23 Sarangadharacharya, Sarangadhara Samhita with Dipika and Gudahartha-Dipika Commentary. Varanasi: Chowkhamba Krishnadas Academy; 2013:p 266. 24 Sarangadharacharya, Sarangadhara Samhita with Dipika and Gudahartha-Dipika Commentary. Varanasi: Chowkhamba Krishnadas Academy;2013:p 269. 25 Mishra Siddhinandan. Rasa Manjari of Acharya Shalinath with Siddhiprada Hindi Translation. Varanasi: Chowkhamba Orientalia;2010:p 71. 26 Mishra Siddhinandan. Rasa Manjari of Acharya Shalinath with Siddhiprada Hindi Translation. Varanasi: Chowkhamba Orientalia;2010:p 74. 27 Mishra Siddhinandan. Rasa Manjari of Acharya Shalinath with Siddhiprada Hindi Translation. Varanasi: Chowkhamba Orientalia;2010:p 75. 28 Mishra Sharma Gulraj. Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Purvardha. ED/3 rd. Varanasi: Choukhamba Orientalia;2007:p 274. 29 Mishra Sharma Gulraj. Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Purvardha. ED/3 rd. Varanasi: Choukhamba Orientalia;2007:p 274-275. 30 Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Uttarardhah. ED/2 nd. Varanasi: Choukhamba Orientalia; 2003:p 44-45. 31 Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Uttarardhah. ED/2 nd. Varanasi: Choukhamba Orientalia; 2003:p 45-46. 32 Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Uttarardhah. ED/2 nd. Varanasi: Choukhamba Orientalia;2003:p 46-47. 33 Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Uttarardhah. ED/2 nd. Varanasi: Choukhamba Orientalia;2003:p 48-49. 34 Sharma Santosh Kumar. Rasa Kamadhenu of Sri Cudamani Mishra with Suvivrtti Hindi commentary, Uttarardhah. ED/2 nd. Varanasi: Choukhamba Orientalia;2003:p 49-50. 35 Madham Shetty Suresh Babu(ed). Yoga Ratnakara. ED/1 st.Varanasi: Chowkhmba Sanskrit Series Office;2005:vol 1.p 469. 36 Madham Shetty Suresh Babu(ed). Yoga Ratnakara. ED/1 st. Varanasi: Chowkhmba Sanskrit Series Office;2005:vol 1.p 469-470. 37 Madham Shetty Suresh Babu(ed). Yoga Ratnakara. ED/1 st. Varanasi: Chowkhmba Sanskrit Series Office;2005:vol 1.p 479. 38 Shastri Ambikadatta. Bhaishajya Ratnavali of Shri Govind Das with Vidyotini Hindi commentary.ED/18 th. Varanasi: Chaukhamba Prakashan;2007:p 427. 39 Shastri Ambikadatta. Bhaishajya Ratnavali of Shri Govind Das with Vidyotini Hindi commentary.ED/18 th. Varanasi: Chaukhamba Prakashan;2007:p 426. 40 Shastri Ambikadatta. Bhaishajya Ratnavali of Shri Govind Das with Vidyotini Hindi commentary. ED/18 th. Varanasi: Chaukhamba Prakashan;2007:p 426. 41 Shastri Ambikadatta. Bhaishajya Ratnavali of Shri Govind Das with Vidyotini Hindi commentary.ED/18 th. Varanasi: Chaukhamba Prakashan;2007:p 425. 42 Shastri Ambikadatta. Bhaishajya Ratnavali of Shri Govind Das with Vidyotini Hindi commentary.ED/18 th. Varanasi: Chaukhamba Prakashan;2007:p 233. 43 Saxena Nirmal. Yoga Tarangini of Trimalla Bhatta. Varanasi: Chaukhamba Sanskrit Bhawan;2007:p 214. 44 Saxena Nirmal. Yoga Tarangini of Trimalla Bhatta. Varanasi: Chaukhamba Sanskrit Bhawan;2007:p 215. 45 Vaishya Shyamsundaracharya. Rasayana Sara. Varanasi: Chowkhamba Krishnadas Academy; 2005: vol 1:p 354.

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Dr. Pooja Krishna Prasad et al. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method ISSN: 2456-3110 REVIEW ARTICLE Sept-Oct 2019 Journal of Ayurveda and Integrated Medical Sciences | Sept - Oct 2019 | Vol. 4 | Issue 5 206 46 Vaishya Shyamsundaracharya. Rasayana Sara. Varanasi: Chowkhamba Krishnadas Academy; 2005: vol 1:p 370. 47 Vaishya Shyamsundaracharya. Rasayana Sara. Varanasi: Chowkhamba Krishnadas Academy; 2005: vol 1:p 372. 48 https://www.sciencedirect.com/science/article/pii/S 16 84118214002102?via%3 Dihub ******************************* How to cite this article: Dr. Pooja Krishna Prasad, Dr. Sangeeta Rao, Dr. Vikram S. A Review on Pottali Kalpana w.s.r. to Kaparda Purana Putapaka method of preparation. J Ayurveda Integr Med Sci 2019;5:196- 206. Source of Support: Nil, Conflict of Interest: None declared. Copyright © 2019 The Author(s); Published by Maharshi Charaka Ayurveda Organization, Vijayapur (Regd). This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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