International Research Journal of Ayurveda and Yoga
2019 | 3,336,571 words
The International Research Journal of Ayurveda & Yoga (IRJAY) is a monthly, open-access, peer-reviewed international journal that provides a platform for researchers, scholars, teachers, and students to publish quality work in Ayurveda, Yoga, and Integrative Medicine. Advised by renowned Ayurvedic experts, IRJAY publishes high-quality review articl...
A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the...
Mridula M K
Assistant Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura
PY Ansary
Professor& HOD Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura
Sara Moncy Oommen
Professor& HOD Dept. Of Dravyaguna vijnana Govt. Ayurveda College Kannur
V V Shincymol
Associate Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura
Sethu R
Assistant Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura
Year: 2022 | Doi: 10.48165/
Copyright (license): Creative Commons Attribution 4.0 International (CC BY 4.0) license.
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[Full title: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect)]
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[Find the meaning and references behind the names: Sara, Sethu, Moncy]
Review Article This work is licensed under a CC BY 4.0 License International Research Journal of Ayurveda & Yoga Vol. 5 (1),126-136, January, 2022 ISSN: 2581-785 X; https://irjay.com/ DOI: https://doi.org/10.47223/IRJAY.2022.5119 A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) Mridula.M.K, 1 P.Y.Ansary, 2 Sara Moncy Oommen 3 V.V.Shincymol 4 Sethu.R 5 1 Assistant Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura 2 Professor& HOD Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura 3 Professor& HOD Dept. Of Dravyaguna vijnana Govt. Ayurveda College Kannur 4 Associate Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura 5 Assistant Professor Dept. Of Dravyaguna vijnana Govt. Ayurveda College Tripunithura INTRODUCTION India has experienced a dramatic demographic transition in the past 50 years with a tripling of the population over the age of 60 years 1 and is expected to reach 158.7 million in 2025 2 . An analysis of morbidity patterns by age indicates that the elderly experiences a greater burden of ailments compared to other age groups 3 and mental health conditions play a significant role in their morbidity and premature mortality 4 . Ageing being a risk factor for neurodegenerative disorders contributes to the Article Info Article history: Received on: 14-12-2021 Accepted on: 20-01-2022 Available online: 31-01-2022 Corresponding author- Mridula. M.K Assistant Professor, Department of Dravyaguna Vijnana, GAC, Tripunithura E-Mail: drmridulamk@yahoo.com ABSTRACT: Ageing and related ailments especially mental health conditions imparts a greater burden in elderly population. Age related dementia including both memory loss and cognitive impairment is a leading contributor of disability. Due to the concern over safety of available pharmacological therapies many people with dementia turn to complementary medicine. Ayurveda, the Indian system of medicine recognises this condition as Medhakshaya (deterioration of intellect) and has given much emphasis on drugs which will promote Medha . Several rasayana drugs in ayurveda are primarily claimed as medhya since they have the ability of mental upliftment. Naladadi ghrita is such a formulation described in rasayana prakarana of Ashtanga hridaya and in this review we tried to analyse individual drug action and their synergetic action. Role of drugs in neuroprotection, learning and memory was analysed by electronic database search. And drugs were also reviewed by ayurveda parameters. Results of the review revealed the role of individual drugs in digestion and various brain functions. combination of drugs may produce an extra therapeutic effectiveness by synergism and can be utilised for the treatment of various CNS disorders including jarajanya medhakshaya. Keywords: Ageing, Dementia, Ayurveda, Rasayana , Neuroprotective Agents, Herbal Medicine
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[Find the meaning and references behind the names: Buddhi, Gupta, Long, Manas, Ayu, Main, Sakthi, Shakti]
Mridula, et al .: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) . ” : 2022; 5 (1):126-136 127 development of dementia in a large number of people 5 . Among all neuropsychiatric conditions, dementia is a leading contributor of disability in the elderly and these shifts in the paradigm may affect the prevalence of dementia in India 6 . A study on the prevalence of cognitive impairment and dementia in community-dwelling Indians from Singapore reported that among elderly Indians the overall prevalence of any cognitive impairment is 24.6% including 1.2% of dementia 7 . Memory loss in elderly will raise concern over cognitive abilities or to general cognitive decline, and not just memory even though some degree of cognitive slowing is a part of normal aging 8 . They can’t transform information quickly to make a decision which shows impairment in speed of processing, working memory, and executive cognitive function 9 . But the safety and long-term therapeutic benefits of currently available interventions remain uncertain and due to these unsatisfactory pharmacological therapies, many people with dementia and cognitive impairment turn to complementary medicine. Present era witnessed a tremendous urge to explore medicinal plants globally for improving cognitive function owing to their less adverse effects. Also, CNS acting drugs are highly dose dependant and always tends to result with addiction accompanied with withdrawal symptoms. Concept of ageing ( jara ) including changes in body and mental functions is beautifully described in classics of Ayurveda . Age( vaya ) is divided into childhood ( balyam ), middle age( madhyam ), and old age ( vridha ) and Acarya Charaka mentioned that cognitive functions like power of understanding ( grahana ), power of retention( dharana ), power of memorizing ( smarana ), speech ( vachana ), and functions of sense organs get affected in old age 10 . Sarangadhara samhita clearly emphasizes that intellect ( medha ) and wisdom ( buddhi ) start to deteriorate between the fourth and ninth decades of life 11 . Being a holistic science Ayurveda gives equal importance to body and mind in health and disease. Ayurvedic principles pointed out the coexistence of body( sarira ), sense organs ( indriya ), mind ( sattva ) and soul( atma ) as ayu and the main motive of Ayurveda is the protection of ayu 12 . ‘Medha’ means intellect or retention and ayurvedic classics used this word synonymously with buddhi, smrti and dhi to denote grahana sakthi (grasping power) and dharana Shakti (retention power) 13 . It provides the power to obtain the knowledge of existing object. Medha can be particularized as an individual’s specific intellectual ability to retain a large amount of knowledge (cognition) and for a long time 14 . Medha affects the happiness or misery of the ‘ayu . So, protecting medha is essential for fulfilment of motive of ayurveda . Among major disabilities faced by elderly, deterioration of memory and learning has considerable impact on their health. Ayurveda recognises this condition as medhakshaya (deterioration of medha ). Acharyas has given much emphasis on drugs which will promote medha (medhya dravyas). Though medhya karma is related to manas , its specific concern with nervous system is undoubtful which is considered as a prabhavajanya 15 They can be utilized for the prevention and treatment of medhakshaya. Several medicinal plants mentioned as rasayana drugs in ayurveda are primarily claimed as medhya since they have the ability of mental upliftment 16 . Descriptions about various rasayanas in the form of rejuvenative recipes, dietary regimen, special health promoting behaviour and drugs can be seen in authentic ayurveda text books. Properly administered rasayanas can provide longevity, memory, intelligence and freedom from diseases. They are classified on the basis of benefit, method of use, or material used and aushadha rasayanas (drugs) plays a major role in rasayana chikitsa . Some of the aushadha rasayanas are organ and tissue specific and those specific to brain tissue are called medhya rasayana . They will help to retard brain aging and helps in regeneration of neural tissues besides producing antistress, adaptogenic and memory enhancing effects 17 . Powder of Glycyrrhiza glabra Linn (yashtimadhu churna), juice of Centella asiatica (L.) Urb (mandukaparni swarasa) , paste of Convolvulus pleuricaulis Choisy (shankhapushpi kalka) and Juice of Tinospora cordifolia (Willd.) Hook.f. & Thomson (guduchi swarasa) are advised to use as medhya rasayana by acharyas 18 .Apart from these single drugs many polyherbal formulations are described in Ayurveda classics which will perform medhya karma . Naladadi ghrita is such a formulation described in rasayana prakarana of Ashtanga hridaya and widely used medicine in Kerala. It contains around 17 herbs and Convolvulus pleuricaulis Choisy ( Shankha pushpi ) is the major ingredient 19 Gupta and Mamidi reported that Naladadi ghrita is effective in the management of ADHD in children. They have observed a significant improvement in ADHD rating scale in children 20 . This review is an attempt to analyse the role of Naladadi ghrita in the management of medhakshaya due to ageing. MATERIALS AND METHODS Organized collection of data from classical text books of Ayurveda and electronic databases (pubmed and google
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[Find the meaning and references behind the names: Raja, Guna, Rasa, Pala]
Mridula, et al .: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) . ” : 2022; 5 (1):126-136 128 scholar). Ayurvedic literature relating to the formulation and ingredients of Naladadi Ghrita is collected from samhithas and nighantus . Botanical sources were identified from Indian Medicinal plants, a compendium of 500 species. Pharmacological evaluations conducted with the part used and phytoconstituents of individual drugs were collected from the research articles available online mainly through PubMed search engine. Ingredients of Naladadi ghritam as per Indian Medicinal Plants Vol (1- 5) 21 (Table 1) Indications 22 1 By regular intake of this ghrita , even mute or retarded persons will become talkative which indicates its action in areas of speech ( Jado api Vagmi Bhavet ) 2 Regular use of this also improves the ability to understand, capacity to retain memories, ability to analyze and draw logical conclusions (Srutadhari) 3 Enhance the intellect and make a person more creative. (Pratibhavan) 4 Regular us will improve general health. (Aroga) Method of preparation. As per the general method, paste of drugs( kalka) , ghee( ghrita ) and liquids( kwatha/swarsa ) will be taken in a ratio of ¼:1:4 and will cook until it attains paka lakshanas 24 . Here as per the textual reference, 1 athaka of ghee (approx.2.56 kg) will be mixed with 10.24 kg of sankhapushpi swarasa and milk each. Then 0.64 kg of kalka prepared with the remaining ingredients will be added to this mixture and will be cooked in mild fire till paka lakshana. Dose -General dose for snehakalpana is 1 pala 25 . But there are various factors to be considered before deciding the dose of a drug. Acharya Caraka stated that the standard dose of a drug is suited for young person( madhyamavastha ) 26 . Sarngadhara elaborated the same by mentioning the age specific doses for powder( churna ), paste( kalka ) and decoctions( kwatha ) 27 . Apart from this strength of the patient and disease, digestive power, bowel, sex, power of drug etc are also the determining factor for dose 28 . So, the dose of Naladadi ghrita should decide considering all these factors since there is no specification of dose in the textual reference. Pharmacological Properties ( Rasadi Gunas ) of the drugs from various Nighantus 29 (Table 2) It is difficult to explain the effect of all medhya drugs since they show varied properties. Nagarjuna opined that the medhya dravyas acts by their achintya veerya (prabhava ). They may act at level of rasa, agni, and srotas . They may stimulate and improve the function of agni 30 . Researches reported the role of digestion and metabolism in control of brain function. Since brain consumes an immense amount of energy relative to the rest of the body, the mechanisms that are involved in the transfer of energy from foods to neurons are likely to be fundamental to the control of brain function. Several gut hormones have been found to influence emotions and cognitive processes 31,32 , Some dietary components have been identified as having effects on cognitive abilities 33,34 . , At level of Srotas , they may improve the circulation of rasa by opening and cleaning the micro channel and then ultimately improve the function of Medha . As per Ayurveda principles, action of a dravya is decided by its rasapanchaka which are ultimately different combination of panchamahabhootas . They possess characteristics of satva, raja and tama . Since medha is attributed to predominance of satva guna , akashiya taijasa and apya dravyas having satva guna predominance will improve medha . Analysis of rasapanchaka of Naladadi ghrita revealed madhura, tikta and katu rasa predominance in the ingredients. They are either madhura or katu in vipaka . Tikta rasa has a direct action on the promotion of medha . It performs their function by its laghu guna , deepana-paachana and srotosodhaka karma. Bitter substances are reported to possess potent effects to stimulate the secretion of gastrointestinal hormones and modulate gut motility 35 . Studies reported humans have bitter taste receptors (25 T 2 Rs) that are expressed in the oral cavity, gastrointestinal and neuroendocrine cells 36 Madhura rasa also by promoting the formation of oja nourishes indriyas , manas and medha . Katu rasa pocess deepana and pachana property. It dialates channels ( srotosodhana ). Seeta veerya and mahura vipaka promotes kapha and enhances dharana karma. Ushna veerya and tikta rasa promotes pitta and enhances grahana and smarana (ie grasping power and memory) 37 . Sankhapushpi ( Convolvulus pleuricaulis Choisy) is the main ingredient of Naladadi ghrita . Acharyas explained the medhya karma of this plant in various classics and it is said to be superior to other medhya dravyas . Hypotensive and tranquilizing effects of the plant is evident from various pharmacological studies. And some clinical studies have shown its beneficial effects in anxiety neurosis 38 . Nahata A etal reported a significant improvement in learning and memory in rats after treatment with ethanolic extract of Convolvulus pleuricaulis Choisy(CP) 39 . A study
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[Find the meaning and references behind the names: Malik, Jai]
Mridula, et al .: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) . ” : 2022; 5 (1):126-136 129 by Jai malik reported neuroprotective activity of CP Extract against 3-NP-induced neurotoxicity and can be further explored for its efficacy against Huntington’s disease 40 . Phytochemical evaluation of the plant revealed the presence of Kampferol, a natural flavonol which pocess a wide range of pharmacological activities including neuroprotective and anxiolytic activity 41 . Nalada (Nardostachys jatamansi DC) is an ingredient of various Ayurveda formulations and acharyas explained its medhya karma . This plant has been claimed to possess antidepressant 42 , sedative 43 , antiparkinsonian 44 and memory enhancing activities 45 .Studies reported significant improvement in learning and memory in young mice after treatment with ethanol extract of the plant. They also reported reversal in aging-induced amnesia of mice. Administration of powdered roots daily for one month showed statistically significantly improvement in latency to falling asleep, duration and undisturbed restful sleep in Indian patients with primary insomnia of up to 5 years duration 46 . Rucker G etal reported that one active sesquiterpene in this plant named valeronone exhibits activities typical for tranquilizers 47 . Madhuka (Glycyrrhiza glabra Linn) is an important ingredient in many ayurvedic formulations. Parle M etal reported a significant improvement in learning and memory in mice after pre-treatment with aqueous extract for 7-days 48 . Also a reversal in scopolamine-induced amnesia 49 , decrease in brain AChE activity 50 , and production of antidepressant-like effect 51 were reported. Various studies reported significant enhancement in spatial memory retention 52 and learning 53 by pretreatment with its aqueous extract. Glycyrrhizin, a saponin present in this plant is one of the most potent hydroxyl radical scavengers 54 Antioxidant activity 55 , Nootropic activity 56 ,Anxiolytic activity and neuroprotective effect 57 of Pureria tuberosa DC is reported. Shete R V etal demonstrated the nootropic effect of Hemidesmus indicus (L.) R. Br. ex Schult 58 Antioxidant activity of various extracts of Vacha (Acarus calamus Linn) in different oxidative-stress models has been reported 59,60,61 .Coadministration of the rhizome extract prevented restraint-induced cognitive impairment in rats 62 .Ethyl acetate extract and a-asarone prevented noise stress-induced memory impairment in rats 63 .Hypnosis-potentiating and hypotensive activities 64,65,66 of the plant is residing in its volatile oil with basarone as major constituent 67 .Neuroprotective 68 , Sedative, and respiraory depressive activities of the rhizomes are also reported 69 . Two bitter principles named acorin and acoretin are reported in this plant 70 . Studies reported a significant free radical scavenging capacity of methanol and aqueous extracts of Katuka rohini (Picrorhiza kurroa Royle ex Benth . ) 71,72 . Studies reported a significant sedative effect in mice after treatment with sandal oil 73 and alpha and beta santalols are responsible for sedative effect of sandalwood preparations 74 . A clinical study reported significant subjective sedative effect by alpha santalol in healthy Thai volunteers 75 Invitro antioxidant activity of Terminalia chebula Retz is reported by various studies 76,77,78 Golechha M etal reported memory enhancing, and antioxidant activity of hydroalcoholic extract of Emblica officinalis Gaertn. in scopolamine-induced cognitive impairment in mice 79 . Antidepressant-like effect in mice was observed by treatment with aqueous fruit extract 80 Pretreatment of rats with hydroalcoholic extract improved cognitive deficit and ameliorated oxidative stress 81 . Gallic acid, methyl gallate, corilagin, furosin and geraniin were identified as the chemical constituents responsible for nitric oxide scavenging activity 82 . Ginger powder and juice is reported to provide protection from oxidative stress 83 , lowers lipid peroxidation and maintains activities of antioxidant enzymes 84 , protection against behavioural dysfunction and Alzheimer-like symptoms in rats 85 . Improvement in cognitive performance, memory impairment and antioxidant markers in cerebral ischemic rats 86,87 were also reported. Studies reported that administration of methanol fruit extract of Piper nigrum Linn improved memory and exhibited anxiolytic and antidepressant effects in spatial memory impairment in rats 88,89 . Enhanced learning and spatial memory in aged rats 90 significant increase in recognition memory 91 and protection of brain against neurotoxic insults 92 by administration of Curcuma longa Linn were reported. Curcumin supplemented-diet improved age-related cognitive functions in rats 93 and significantly improved cognitive tasks, locomotor activity, oxidative defence in mice 94 . Curcumin also protected against acute ethanolinduced memory deficit 95 significantly reversed brain oxidative damage 96 . Berberine, a major alkaloid of Berberis arista sims is reported to possess antidepressant activity 97 . Ghee is mentioned as best suited for those desirous of dhi (intelligence), smrithi(memory) and medha by acharyas. It is said to be beneficial for mental alertness and memory in adults as well in children. When processed with appropriate medicines, its curative power is immense and
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[Find the meaning and references behind the names: Fast, Nil]
Mridula, et al .: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) . ” : 2022; 5 (1):126-136 130 can be used in several diseases 98 . Acharya Vagbhata suggested daily intake of ghee before food for vayasthapana 99 .Several ghee-based formulations are recommended by acharyas for the preservation and promotion of brain and neurological health especially in chapters dealing with Unmada and apasmara . These include Kalyana ghrita, Mahakalyana ghrita, Mahapaishaachika ghrita , Brahmi ghrita, and Lashunadi ghrita 100 . Ingredients of Naladadi ghrita contain many lipophilic terpenoids, flavanols etc. So, ghee medium will help to extract the maximum therapeutic properties of ingredients in to the formulation . Blood-brain barrier acts as a major obstacle to the delivery of drugs to the central nervous system. Membrane separating the central nervous system tissue and circulating blood is lipophilic. Thus, it selectively permits the passage of lipids and lipid-soluble drugs across it. Therefore, any drug given in the form of ghee will not only be processed and absorbed fast but also be able to reach some of the most hard-to-reach areas of the body like the CNS. This clarifies the better efficacy of various psychotropic drugs given in the form of ghee in CNS diseases 101 . Acharya Vagbhata added Ksheera as an ingredient in Naladadi ghrita . Ksheera is the best jeevaneeya dravya and its daily use is will do rasayana karma . Goksheera is said to be having rasayana property. Also , balya, brimhana and kshayahara properties of the ksheera could make it to use in rasayana chikitsa. DISCUSSION Review of individual drugs of Naladadi ghrita revealed their role in digestion and various brain functions. Madhura, katu and tikta rasa predominant drugs by their nourishing role in the indriyas and manas , deepana and pachana properties and srotosodhana action helps to maintain the normal functioning of doshas and anulonma gati of vata. Srotosodhana action helps to normalise manovahasrotas also. Since regular use of this ghrita enhances physical health, it can be utilised as a nervine tonic. Researchers identified a relationship between enteric nervous system and neurological disorders 102 . Concept of gut-brain axis links emotional and cognitive centres of the brain with peripheral intestinal functions and importance of gut microbiota in influencing these interactions are evident from recent researches 103 . Studies has revealed a linking between several pathophysiological conditions with an impaired gut microbiome, the effects of which extend beyond the gut and in particular to the brain. This microbiome-gut-brain axis considerably affects neural function and pathophysiology like susceptibility to autism, neurodegenerative diseases 104 . Considering these factors, we can identify Naladadi ghrita as an ideal drug for various neurological conditions including Dementia, Parkinsons disease, Alzheimer’s disease etc. Ayurveda system of medicine uses a single drug and polyherbal formulations for the treatment of various ailments. Use of polyherbal formulations dated back to the time of acharya sarngadhara and is said to be achieve extra therapeutic effectiveness. Scientific studies have revealed that combination of plants will produce a greater result as compared to individual use of the plant and also the sum of their individual effect through a positive herb-herb interaction known as synergism 105 . Hence combination of drugs of Naladadi ghrita also may produce an extra therapeutic effectiveness by synergism and can be utilised for the treatment of various CNS disorders including jarajanya medhakshaya. CONCLUSION Satisfactory effect and safety of Ayurvedic polyherbal formulations making them one of the highly selected drugs of choice for treatment and prevention of various ailments. Naladadi ghrita is such a formulation indicated in rasayana prakarnana of Ashtanga hridaya and literature review of its individual drugs revealed its action on memory, learning and other neuroprotective activities Correct and rational use of this formulation will help to prevent and treat various central nervous system disorders including Jarajanya medhakshaya . Acknowledgements:- Nil Conflict of Interest – None Source of Finance & Support - Nil REFERENCES 1 Government Of India. National Programme For The Health Care Of The Elderly (NPHCE), Operational Guidelines. New Delhi: Government Of India; 2011 2 United Nations Department Of Economic And Social Affairs, Population Division. World Population Prospects (2008 Revision). 2008. Available: Http://Esa .Un.Org/Unpp/Index.Asp?Panel=2 . 3 National Sample Survey Organisation. National Sample Survey, 60 th Round, Report No. 507 (60/25.0/1). New Delhi: Ministry Of Statistics And Programme Implementation, Government Of India; 2006. Morbidity, Health Care And The Condition Of The Aged.
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[Find the meaning and references behind the names: Ahmad, Nepal, Sharma, Joshi, Mar, Akbar, Shamsa, Subhash, Don, Rao, Satyanarayana]
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[Find the meaning and references behind the names: Chandana, Rock, Guru]
Review Article This work is licensed under a CC BY 4.0 License Table 1 Ingredients of Naladadi ghritam as per Indian Medicinal Plants Vol (1-5) 21 Drugs Botanical name Family Part used Nalada Nardostachys jatamansi DC Valerianaceae rhizome Katukurohini Picrorhiza kurroa Royle ex Benth Scrophulariaceae rhizomes Payasya Pueraria tuberosa DC Fabaceae tuberous roots Madhuka Glycyrrhiza glabra Linn Fabaceae roots Chandana Santalum album Linn Santalaceae heartwood Sariba Hemidesmus indicus (Linn.)R.Br Asclepiadaceae roots,stem Vacha Acorus calamus Linn Araceae Rhizome Haritaki Terminalia chebula Retz Combretaceae fruits Vibhitaki Terminalia belerica Roxb Combretaceae fruits Amalaki Emblica officinalis Gaertn Euphorbiacaeae fruits Sunthi Zingiber officinale Roxb Zingiberaceae rhizome Maricham Piper nigrum Linn Piperaceae fruits Pippali Piper longum Linn Piperaceae roots,dried spikes Haridra Curcuma longa Linn Zingiberaceae rhizomes Daruharidra Coscinum fenestratum (Gaertan.) Colebr Menispermaceae stem Patola Trichosnthes cucumerina Linn Cucurbitaceae wholeplant Saindava Rock salt Sankhapushpi Convolvulus pleuricaulis Choisy Convolvulaceae wholeplant Table 2 Pharmacological Properties ( Rasadi Gunas ) of the Drugs from various Nighantus 29 Rasa Guna Veerya Vipaka Doshaghnata Karmas Nalada Tikta, Kashaya madhura Laghu Seeta Katu Tridoshanut Medhya, balyam, balakantida Katukurohini Katu Tikta Laghu Ruksha,sara, Seetam Katu Kapha pttahara, Dipana, Bhedini,Hridya, Jvarahara Payasya Madhura Guru Snigdha Seeta Madhura Vatajit,Pittasrajit kaphakrit Balya,rasayana, Swaryam ,jivaniyam ,Brimhaneeyam,veerya vridhikrit Madhuka Madhura tikta Guru Snigdha Seeta Madhura Vatapitta kaphapaham balaswaravarnakrit Chandana Tikta Madhura Katu kashayam Laghu Ruksha Seeta Katu Pittahara, Kaphahara, Dahaprasamana, Varnya,Hridya, Trishnahara,,Krimighn a, Vishaghna Sariba Madhura tikta Guru Snigdha Seeta Madhura Kaphavataharam Rakthapitha prasamani Rakthasodhaka Dipanam,Amanasanaa m, Jwaraharam. Vacha Katu Tikta Laghu,ushna ,tikshna,ruks ha tikshna Ushna Katu Vatahara, Kaphahara Dipana,Pachana Medhya,Ayushyam,Smr itivardhini,vakswarapr ada, Budhi smritiprada
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[Find the meaning and references behind the names: Ida]
Mridula, et al .: A Review on the Role of Naladadi Ghrita (A Polyherbal Medicated Ghee) in the Management of Jarajanya Medhakshaya (Age Related Deterioration of Intellect) . ” : 2022; 5 (1):126-136 136 Haritaki Kashaya, Katu, Tikta, Amla, Madhura Laghu ruksha Ushna Madhura Tridoshaghnam Rasayana,dipana,papa kha,Medhya, ayushyam,budhindriya balapradam,smritikara kam Vibhitaki Kashaya Katu tikta Ruksha Laghu Ushna Madhura Kaphapittajith, Bhedaka,vaiswaryanal ksanamll Amalaki Pancharasa lavana varjita Ruksha Laghu sara Seeta Madhura Tridoshajit, Rasayana,dhatuvridhik rit Sunthi Katu Laghu Snigdha Ushna Madhura kaphavataghnam Anulomana,DeepanaP achanam,swaryam Maricham Katu, Tikta Laghu, ruksha, Tikshna Ushna Katu Kaphavataharam pithavardhakam Dipana,pachana Ruchya,chedana, Pippali Madhura Katu Tikta Laghu Snigdham anushna Madhura vatakaphaharam Dipaneeyam rasayanam Haridra Katu Tikta Ruksha ushna Ushna Katu Kaphapithgni Vatasranut. Krimighna,kushtaghna, Varnya,Vishaghna, Pramehaghna Daruharidra Tiktam katu Ruksha ushna Ushna katu Kaphapithajit Doshapacana Netramayaharam Patola Tikta, Katu Laghu, ruksha ushna katu tridoshashamanam Vrishyam, varnyam, Dipana,pachani Saindava Saswadu laghu Anushnam tridoshaghnam Vrishyam,hridyam Sankhapushpi Katu Tikta Kashaya Sara Seeta katu kaphapithaghni balya,ayushyam, medhya,rasayanam,mo hanasakam,manasarog ahrit,smritikantibalagn ida,swarakarini