Chandraprabha Vati – A Formulation For Mootrakrichhra – A Literary Review

[Find the meaning and references behind the names: Bala, Mode, Isra, Modern, Choice, Class, Sharma, Scholar, Pal, Rog, Pain, Show, September, Main, August, Data, Reetu, Meena, Shivani, Light, Strong, Factor, Mohar, Uti, Nia, Ras]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 328 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 Chandraprabha Vati – A Formulation For Mootrakrichhra – A Literary Review Dr.Varad Charkha 1 , Dr.Shivani Sharma 2 , Dr.Mohar Pal Meena 3 , Dr.Reetu Sharma 4 1- P.G. Scholar, P.G. Department of Ras Shastra, NIA, Jaipur 2- P.G. Scholar, P.G. Department of Rog Nidana & Vikriti Vijnana, NIA, Jaipur 3- Associate Professor, P.G. Department of Ras Shastra, NIA, Jaipur 4- Assistant Professor, P.G. Department of Rog Nidana & Vikriti Vijnana, NIA, Jaipur SJIF Impact Factor : 5.69 ISRA Impact Factor : 1.318 ISSN:2581-785 X Review Article Volume: 3 Issue: 9 Abstract: Mootrakrichhra is a disease of Mootravaha Srotas and mentioned in all main Ayurvedic texts . Mootrakricchra is a Tridoshaj Vyadhi and its symptoms are compared with Urinary tract infections (UTI) in modern texts. Main symptoms of Mootrakrichhra are pain and difficulty in micturition. Various formulations have been mentioned in ayurvedic texts for the treatment of Mootrakricchra . One of those formulations is Chandraprabha vati . Chandraprabha vati is a herbo-mineral preparation having 37 drugs. Though the efficacy of Chandraprabha vati in the above-mentioned condition is observed practically, its mode of action is not clear. In this article we have attempted to throw a light on a probable mode of action of Chandraprabha vati in Mootrakrichhra . Ingredients of Chandraprabha vati possess properties such as mutrala, deepana-pachana, tridoshaghna, sheeta virya and rasayana. Samprapti (pathophysiology) of Mootrakrichhra can be broken down by these properties. Experimental studies have proven the antioxidant & antimicrobial action of Chandraprabha vati. Thus, it stands as a formulation of choice in treatment of Mootrakricchra Keywords :- Chandraprabha vati , Herbo-mineral , Micturition , Mootrakricchra

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IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 329 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 INTRODUCTION: Ayurveda , the Indian system of medicine, includes treatment using herbal or metallic or herbo-metallic formulations. Chandraprabha vati is a herbo-mineral formulation containing 37 ingredients of both herbal and mineral origin. It is being used in practice by Ayurveda physicians since centuries. Mootrakrichhra is one of the many indications of Chandraprabha vati . Mootrakrichhra 1 means disease in which there is difficulty in urination is called Mootrakrichhra . It is a disease of Mootravaha Srotasa . In Ayurveda texts, Mootrachhrichra is described by various Acharyas . In Trimarmiya Adhyaya 2 , Acharya Charaka described Mootrakrichhra . Acharya Kashyapa 3 had also described the sign and symptoms of Mootrakricchra in Vedna Adhyaya . In Modern medicine, Mootrakrichhra symptoms are similar to that of urinary tract infection (UTI). Women are at greater risk of developing a UTI as compared to men due to shorter length of urethra, absence of prostatic secretions and pregnancy. Nowadays UTIs are the most common infections. About 40% of women and 12% of men experience symptomatic UTI at least once during their lifetime, and as many as 40% of affected women show recurrent UTI 4,5,6,7 . Urinary tract infection is potentially a serious condition and may lead to complications like chronic pyelonephritis and chronic renal failure. There are effective antibiotics for UTI but they have their own limitations. How to Cite the Article : Dr.Varad Charkha, Dr.Shivani Sharma, Dr.Mohar Pal Meena, Dr.Reetu Sharma, Chandraprabha Vati – A Formulation For Mootrakrichhra – A Literary Review, IRJAY, September: 2020 Vol- 3, Issue-9; 328-344; Doi: https://doi.org/10.47223/IRJAY.2020.3911 Article received on-3 Sept Article send to reviewer on-5 Sept Article send back to author on-19 Sept Article again received after correction on -24 Sept Corresponding Author : Dr.Varad Charkha, P.G. Scholar, P.G. Department of Ras Shastra, NIA, Jaipur, Email id varadcharkha 113@gmail.com

[Find the meaning and references behind the names: Stand, Glow, Vata, Long, Shathi, Madhav, Kamala, Pandu, Afi, Kasa, Pitta, Shati, Khanda]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 330 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 AIMS AND OBJECTIVE To understand the mode of action of Chandraprabha vati in Mootrakricchra. MATERIAL AND METHODS Various Ayurvedic texts have been studied to gather all the relevant information for this article. Ayurvedic texts mainly used for this article are Charak Samhita, Sharangadhar Samhita , Madhav Nidan ,Kashaypa Samhita and Rasratna Samucchya . Information on Mootrakrichhra is also collected from various journals, magazines, research articles and internet. Review of Chandraprabha vati – Chandraprabha vati is mentioned in Sharangdhar Samhita Madhyama Khanda 7/40-49 8 and Bhaishajya Ratnavali pramehachikitsa 102-110 9 . Though 5 formulations are named as Chandraprabha vati in Rasayogasagar 10 , above mentioned references are most commonly used. It can be prescribed in prameha, Mootrakrichhra, Ashamari, Mootraghata, Andavridhhi, Pandu, Kamala, Halimaka, Kasa, Shwasa, Kushtha, Agnimandya, Arochaka and other diseases due Vata, Pitta & Kapha . It also acts as Balya, Vrishya and Rasayana 11 The name Chandraprabha suggests the raised glow on skin after long consumption of the formulation. The term Chandraprabha is also said to be generated due to the fact that it represents the 1 st ingredient of the formulation. There is difference in opinion of experts about the drug Chandraprabha. Though it is generally considered to stand for Karpura (Cinnamomum camphora), some experts consider it to be Shathi (Hemidesmus indicus) or Shatavari (Asparagus racemosus). 12 AFI considers Chandraprabha as Karpura.

[Find the meaning and references behind the names: Vacha, Longa, Piper, Ribes, Musta, Vaca, Table, Amruta]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 331 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 TABLE NO. 1 -Ingredients of Chandraprabha vati 13 Sr.No. Name of ingredient Scientific name Quantity 1 Chandraprabha (karpura) Cinnamomum camphora 3 g 2 Vacha Acorus calamus 3 g 3 Musta Cyperus rotundus 3 g 4 Bhunimba (kiratatikta) Swertia chirayta 3 g 5 Amruta (guduchi) Tinospora cordifolia 3 g 6 Daruka (devadaru) Cedrus deodara 3 g 7 Haridra Curcuma longa 3 g 8 Ativisha Aconitum heterophyllum 3 g 9 Darvi Berberis aristata 3 g 10 Pippalimula Piper longum 3 g 11 Chitraka Plumbago zeylanica 3 g 12 Dhanyaka Coriandrum sativum 3 g 13 Haritaki Terminalia chebula 3 g 14 Bhibhitaka Terminalia bellirica 3 g 15 Amalaki Emblica officinalis 3 g 16 Chavya Piper retrofractum 3 g 17 Vidanga Embelia ribes 3 g 18 Gajapippali Scindapsus officinalis 3 g

[Find the meaning and references behind the names: Sugar, Vida, Sita, Iron, Danti, Barley, Ash, Ela, Rock, Crystal, Copper, Salt, Black]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 332 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 19 Sunthi Zingiber officinalis 3 g 20 Maricha Piper nigrum 3 g 21 Pippali Piper longum 3 g 22 Swarnamakshika bhasma Calcined Copper pyrite 3 g 23 Yava kshara Dried water-soluble ash of barley 3 g 24 Sarji kshara Impure sodium bicarbonate 3 g 25 Saindhava lavana Rock salt / Indian rock salt 3 g 26 Sauvarchala lavana Black Salt/Sodium sulphate mixed with sodium chloride 3 g 27 Vida lavana Ammonium chloride 3 g 28 Trivrut Operculina turpethum 12 g 29 Danti Baliospermum monatum 12 g 30 Patraka (tejapatra) Cinnamomum tamala 12 g 31 Tvak Cinnamomum verum 12 g 32 Ela Elletaria cardamomum 12 g 33 Vamshalochana Bambusa arundinacea 12 g 34 Lauha bhasma Calcined iron 24 g 35 Sita Crystal sugar 48 g 36 Shilajatu Black bitumen 96 g 37 Guggulu Commiphora wightii 96 g

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IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 333 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 Review of Mootrakrichhra – Mootrakrichhra is a Tridoshaj Vyadhi 14 .Its etiological factors are- Nidana : There are many nidana of mootrakrichhra explained by Acharyas in different Ayurvedic texts as mentioned in Table no. 2 TABLE NO. 2 : Nidana of Mootrakrichhra Types: Acharyas have described 8 types of Mootrakrichhra except acharya Vagbhata as he mentioned only Doshaj Mootrakrichhra . Aharaja Nidana Viharaja Nidana Partantra Nidana 1. Adhyashana 15 1. Yana gamana 1. Kaphaja arsha 16 2. Ajirna 17 2. Ativyayama 2. Ajirna 18 3. Ruksha anna sevana 3. Aghata 3. Vasti vidradhi 19 4. Tikshna aushadha sevana 20 4. Atinritya 4. Udavarta 21 5. Ruksha madya sevana 22 5.Gorvarna stri sevana 23 5. Gulma 24 6.Anoopa Matasya 6.Avyayama 7.Katu, amla, lavana rasa ati sevana 25 7.Shrama 26 8.Usna madyapana 27 8. Sheetal jal sevana 9.Pitta prakopak dravya 28 9.Vegavarodh 10.Ati Bhojan 10.Nityaprasang 11.Druta prishtha yana

[Find the meaning and references behind the names: Roopa, Classic]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 334 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 Roopa : There are 8 types of mootrakrichhra and their symptoms are explained by Acharyas in various classic Ayurvedic texts. Increased frequency, Hesitancy and dysuria are the main clinical features of mootrakrichhra. Samprapti 29 Nidan Sevana (Rookshannaativyayama , nityadrutaprustayana (Matsya,Madya,Upasargaja) / Katvamlalavanasevana/Ajeerna,Vishamabojana ) Vata/Pitta/Kapha prakopa Tridosha prakopa Agnimandya Amotpatti sthana sanshraya in Mootravaha srotas kshobha in Mootramarga Mootrakrichhra

[Find the meaning and references behind the names: Act, Better, Normal, Body, Basic, Major, Ama, Get, Agni, Role]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 335 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 DISSCUSSION Mootrakriccha is a tridoshaj vyadhi and chandraprabha vati is a tridoshahara, rasayana and mutrala drug. Chandraprabha vati is a combination of 37 drugs which acts on tridosha and helps in breaking down pathophysiology of mootrakricchra . Properties of these drugs and their probable role is discussed in table no.3. Shilajatu and Guggulu are the main constituents of CPV. Guggulu is considered as one of the best drugs for reducing aggravated vata along with diuretic nature. As Mootrakrichhra is also a Tridoshaj vyadhi having main symptoms as pain i.e. krichhrta, so it helps in balancing vitiated vata and reducing these symptoms. Shilajatu is a rasayana which helps in maintaining the normal functioning. Most of the drugs in CPV are Tridoshhar and Mutrala in nature and directly act on the mootravaha srotas , Hence they help in relieving the symptoms of Mootrakrichhra . Drugs like chandraprabha (Karpura), Chitraka, Mustaka etc. possess Deepanapachana properties which help in increasing appetite and eliminating Ama from the body and relieving symptoms by acting on the pathogenesis and doing samprapti vighatana . Drugs such as Haridra, Vacha , Devdaru, Trikatu ,Gajpippali have antimicrobial properties that help in eliminating any microbial infection Vida lavana acts as vatanulomaka and shoolanashaka which helps in reducing the symptoms of mootrakricchra. Mode of action of chandraprabha vati on mootrakrichhra - Chandraprabha vati is indicated for all types of Mootrakrichhra 30 . The formulation Chandraprabha Vati as a combination of many drugs is rasayana , tridoshaghna , mutrala with deepanapachana and sheeta veerya properties 31 . Owing to these properties, it helps in regulation of the agni and elimination of ama . Thus, it overcomes the basic pathogenesis of Mootrakrichhra. Other major ingredients possess properties such as sheeta veerya , 32 agnideepana, 33 vatahara, 34 and rasayana 35 This helps get the better of the pittaja lakshana which are observed in all types of Mootrakrichhra .

[Find the meaning and references behind the names: Dosha, Natural, Guna, Dosh, Snigdha, Tonic, Proper, Property]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 336 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 TABLE NO.3: Role of individual drugs Chandraprabha (Karpura) It helps in balancing all the doshas . Its Tikta rasa subsides kapha , Madhura rasa subsides Vata and its sheeta virya subsides pitta dosha . It stimulates kidneys and help in proper micturition 36 Vacha Due to ushna and tikshna property of vacha it helps in proper formation of urine. It also acts as an anodyne (Drug used to lessen pain through reducing sensitivity of the nervous system) 37 . Musta It is a natural diuretic hence useful in the treatment of Mootrakrichhra 38 . Used as a tonic. Kirattikta It is a tridosha shamak drug. Tikta rasa subsidses kapha-pitta dosha and ushna virya subsides vatakapha dosha 39 . Guduchi It is a Rasayana,Balya and Tridoshashamak auosadhi. 40 Daruka (Devadaru) Due to its snigdha and usna property it balances the vitiated vata dosha hence an effective anodyne drug. Its snigdha and usna properties help in the proper formation of urine and an effective drug in mootrakrichha 41 Haridra Due to usna virya it subsides vata and kapha dosha and due to Tikhta rasa it vitiates pitta dosha 42 Ativisha It is a tridoshshammak 43 drug. Pippalimula due to its snigdha guna it balances the vitiated vata dosha and it is madhura in vipaka so it acts as a diuretic. Chitraka usna and tikshna-vata dosh shamak

[Find the meaning and references behind the names: Patra, Roots, Bio, Chemical, Phala]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 337 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 Dhanayak -It is a tridoshhar drug and used in Mootrakrichhra 44 Haritaki Rasayana,tridoshhar mainly vata shamak ,diuretic 45 . Bhibhitaka Tridoshhar 46 ,Vednasthapana Amalaki Tridoshhar , Diuretic, Rasayana , used in Mootrakrichhra 47 . Chavya It has similar action like that of Pippali and Gajapippali owing to their similarity in chemical composition 48 Vidanga Best in the krimighna drugs 49 Useful in UTI. Gajapippali Chavika phala is known as Gajapippali . It is krimighna in action 50 Trikatu Acts as bio-enhancer in CPV. Itself possesses antibacterial property. Thus, it is beneficial in UTI. Yavakshara Reduces pain and difficulty in micturition 51 Sajjikshara It possesses ushna and katu property and thus acts as krimighna 52 Saindhava lavana Vibandaghna and tridoshajeet 53 Sauvarchala lavana Laghu, ushna & vishada property containing sauvarchala lavana acts as vibandaghna 54 Vida lavana Due to its teekshna, ushna & deepana property, vida lavana acts as vatanulomaka and shoolanashaka 55 Trivit Roots of Trivrit are said to the best among all purgatives 56 It removes alleviated tridosha from urinary tract. Danti Ashukari and vikasi, 57 ashmarighna Tvak and Patra Being ushna and teekshna , tvak stimulates kidneys and acts as diuretic 58 Ela Ela has mentioned to be useful in mutrakricchra by many texts 59 Vanshalochana It is Kashaya madhura, madhura vipaka and sheeta virya . It acts as diuretic and helps curing baddhamutrata (retention of urine) 60 Loha Acts as rasayana as well as jantughna .

[Find the meaning and references behind the names: Cast, Ten, Patient, Nil, Female, Shweta, Case, Study]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 338 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 In previous studies on CPV, it is clearly mentioned that CPV is a potential source of antioxidants and antimicrobial agent that can be effectively used to remove the invading and persisting bacterial population in the bladder and kidney 62 . The external supplementation of zinc, as in CPV, not only restores the depleted zinc pools in the body fluids, but also acts as a cytotoxic agent to the bacteria 63 . A case report of 25 years old female patient showed reduction in signs and symptoms as well as bacterial growth, nitrites, leucocyte esterase, cast in urine. CPV was administered 100 mg 2 BD along with Brihatyadi ksheerkashayam (50 ml BD) and Shweta parpati (500 mg with 1 litre of water in ten divided doses) 64 . So, this review study and previous studies clearly shows CPV as an effective drug for Mootrakrichhra. CONCLUSION Chandraprabha vati is a commonly used drug in Mootrakrichhra and it helps in reducing the symptoms as well as maintain the proper functioning of kidneys. This drug is very effective in Mootrakrichhra due to various properties such as antimicrobial agent and acting directly as a diuretic. Sita It is sheeta, snigdha and madhura in property. This helps in reducing unbalanced vata and pitta dosha in urinary tract. Guggulu Guggulu being ushna acts on vata. It is one of the best remedy for alleviated vata. Teekshna property of guggulu enhances its mootrala property 61 Acknowledgement:- Nil Financial Assistant:- Nil Conflict of interest :- Nil

[Find the meaning and references behind the names: Heiskanen, Shri, India, Dis, Kuosmanen, Pandita, Hemraj, Care, Delhi, Vijay, Stamm, Shastri, Lipponen, Clin, Krishnadas, Motilal, Narendra, Pandit, Part, Siitonen, Year, Dutt, Rakshit, Vaidya, Nath, Kaviraj, Hindi, Roberts, Kantha, Dipika, Prakashan, Nat, White]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 339 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 REFERENCES 1 Vijay rakshit and shri kantha dutt Madhavkar ;Madhav Nidan; Madhukosha Sanskrit commentary, hindi commentary by Narendra Nath. Shastri, Motilal Banarasidas, Delhi, edition 2005,Ma.Ni.30/1-2,Page no.205 2 Yadavaji Trikamaji ,Charaka, Charak Samhita, Chakrapanidatta’s Ayuredadipika Sanskrit commentary Varanasi, Chaukhambha Orientalia;2015, ,Chikista Sthana ,chapter 26,Page no.599 3 Pandit Hemraj Sharma, Kashypa Samhita, Vidyotini Commentary,Ka.su.25/21 Chaukhambha Sanskrit Sansthan, Delhi ,Reprint: 2013,Page no. 34 4 Foxman B. The epidemiology of urinary tract infection.Nat Rev Urol 2010;7:653-60 5 Ikäheimo R, Siitonen A, Heiskanen T, Kärkkäinen U, Kuosmanen P, Lipponen P, et al. Recurrence of urinary tract infection in a primary care setting: Analysis of a 1-year follow-up of 179 women. Clin Infect Dis 1996;22:91-9. Stamm WE, McKevitt M, Roberts PL, White NJ. Natural history of recurrent urinary tract infections in women. Rev Infect Dis 1991;13:77-84. 6 Kunin CM. Urinary tract infections in females. Clin Infect Dis 1994;18:1-10. 7 Pandit Sarangdharacharya, Sharangdhar Samhita, Sanskrit Commentary Dipika by Adhamalla, Madhyam Khanda, 7/40-49, Chaukhamba Orientalia, Varanasi, India, Reprint 2018, Page 200 8 Kaviraj Shri Ambikadatta Shastri, Bhaishajya Ratnavali, Prameha Chikitsa/102-110, Chaukhamba Prakashan, Varanasi, Reprint 2018, Page no. 730 9 Vaidya Pandit Hariprapanna Sharma, Rasayogasagar, Part 1, 51-55, Choukhamba Krishnadas Academy, Varanasi, Reprint 2010, Page no.424 10 Kaviraj Shri Ambikadatta Shastri, Bhaishajya Ratnavali, Prameha Chikitsa/102-110, Chaukhamba Prakashan, Varanasi, Reprint 2018, Page no. 730 11 Pandit Sarangdharacharya, Sharangdhar Samhita, Sanskrit Commentary Dipika by Adhamalla, Madhyam Khanda, 7/40-49, Chaukhamba Orientalia, Varanasi, India, Reprint 2018, Page 201 12 Ayurvedic Formulary of India, Part-1, 12:10, 2 nd edition, 2003, Government of India, Delhi

[Find the meaning and references behind the names: Sutra]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 340 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 13 Yadavaji Trikamaji,Charaka, Charak Samhita, Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015: Chikista Sthana ,chapter 26/33 Page no.599 14 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015, by,Chikista Sthana ,chapter 26/32 Page no.599 15 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015, by,Chikista Sthana ,chapter 26/32 Page no.599 16 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary by,Chikista Sthana ,chapter 14/17,Varanasi,Chaukhambha Orientalia;2015,Page no.503 17 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015 Chikista Sthana ,chapter 26/32,Page no.599 18 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary Varanasi,Chaukhambha Orientalia;2015, Chikista Sthana ,chapter 15/49,Page no.517 19 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015, sutra Sthana ,chapter 17/101 Page no.104 20 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary Varanasi,Chaukhambha Orientalia;2015, Chikista Sthana ,chapter 26/32,Page no.599 21 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary, ,Varanasi,Chaukhambha Orientalia;2015,Page no.597 22 Yadavaji Trikamaji,Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary Varanasi,Chaukhambha Orientalia;2015, Chikista Sthana ,chapter 26/32, Chikista Sthana ,chapter 26/8 Page no.599

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IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 341 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 23 Harihar prasad Tripathi ,Harita Samhita,Treetiya sthan 39/5-7 Chaukhambha Krishandas academy Varanasi,India,2 nd Edition:2009,Page no. 392 24 Yadavaji Trikamaji Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary, ,Chaukhambha Orientalia;2015, Chikista Sthana ,chapter 5,Varanasi Page no.435 25 Harihar prasad Tripathi ,Harita Samhita,Treetiya sthan 39/5-7 Chaukhambha Krishandas academy Varanasi,India,2 nd Edition:2009,Page no. 392 26 Harihar prasad Tripathi ,Harita Samhita,Treetiya sthan 39/5-7 Chaukhambha Krishandas academy Varanasi,India,2 nd Edition:2009,Page no. 392 27 Harihar prasad Tripathi ,Harita Samhita,Treetiya sthan 39/5-7 Chaukhambha Krishandas academy Varanasi,India,2 nd Edition:2009,Page no. 392 28 Harihar prasad Tripathi ,Harita Samhita,Treetiya sthan 39/5-7 Chaukhambha Krishandas academy Varanasi,India,2 nd Edition:2009,Page no. 392 29 Yadavaji Trikamaji,Charaka,Charak Samhita,Chakrapanidatta’s Ayuredadipika Sanskrit commentary,Varanasi,Chaukhambha Orientalia;2015: Chikista Sthana ,chapter 26/33 Page no.599 30 Prof K.R srikantha murthy Sarangadhara Samhita of sarangadharacharya Ayurveda vidwan. Choukambha Orientalia madhyama khanda 7 thchapter, vatikalpana 45 th sloka pg no. 105. 31 sri Arumanoor parameswaran and Dr.K.V.Ramankutty varrier and edited by Dr.K.Murali Yogamanjari part 1 st Ashtavaidyan P.T.N Vasudevan moos page number 103 to 106. 32 Rasaratna samuchchaya translated by Ashok D. Sajpute published by. chaukhamba Sanskrit pratishthan. 108 sloka Page number 41. 33 Dr. J.L.N. Sastry foreward by K.C chunekaDravya guna vijnana, study of Essential medicinal plants in Ayurveda. published by choukambha orientalia Varanasi. Page number 119. 34 Ashok. D. Sajpute Rasaratna samuchchaya published by. chaukhamba Sanskrit pratishthan., 32 sloka Page number 136.

[Find the meaning and references behind the names: Shukla, Prakash, Varga, Bharti]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 342 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 35 Ashok. D. Sajpute Rasaratna samuchchaya published by. chaukhamba Sanskrit pratishthan. 76 sloka Page number 33.) 36 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no. 198 37 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi, 2012 page no.28 38 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no.372 39 Prof. Krishnachandra Chunekar, Bhava Prakash, Haritakyadi Varga/155, Chuakhamba Bharti Academy, Varanasi, India, Reprint 2013,Page no. 20 40 Prof. Krishnachandra Chunekar, Bhava Prakash, Guduchyadi Varga/9, Chuakhamba Bharti Academy, Varanasi, India, Reprint 2013,Page no.257 41 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no.76 42 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no.163 43 Prof. Krishnachandra Chunekar, Bhava Prakash, Haritakyadi Varga/214, Chuakhamba Bharti Academy, Varanasi, India, Reprint 2013,Page no.122 44 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no.324 45 Prof. Krishnachandra Chunekar, Bhava Prakash, Haritakyadi Varga/22, Chuakhamba Bharti Academy, Varanasi, India, Reprint 2013,Page no.5 46 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 239 47 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 760 48 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi, 2012 page no.336 49 Acharya Vidyadhar Shukla and Prof. Ravidatta Tripathi, Charak Samhita, Sutra Sthana, 25/40, Chaukhamba Sanskrit Pratishthan, Delhi, India, Reprint 2006, Page no. 338

[Find the meaning and references behind the names: Kale, Evangeline, Rajesh, Print, Ganesha, Shankar, Christina, Swetha, Ganesh, Christa, Viswanathan, Landa, Mice]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 343 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 50 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 289 51 Acharya PV Sharma, Dhanwantari Nighantu, Shatapushpadi/18, Chaukhamba Orientalia, Varanasi, India, Reprint 2008, Page no. 73 52 Acharya PV Sharma, Dhanwantari Nighantu, Shatapushpadi/21, Chaukhamba Orientalia, Varanasi, India, Reprint 2008, Page no. 73 53 Acharya PV Sharma, Dhanwantari Nighantu, Shatapushpadi/27, Chaukhamba Orientalia, Varanasi, India, Reprint 2008, Page no. 74 54 Anantaram Sharma, Sushruta Samhita, Sutra Sthana, 46/317, Chaukhamba Surbharati Prakashan, Delhi, India, Reprint 2013, Page 425 55 Acharya Vidyadhar Shukla and Prof. Ravidatta Tripathi, Charak Samhita, Sutra Sthana, 27/302, Chaukhamba Sanskrit Pratishthan, Delhi, India, Reprint 2006, Page no. 419 56 Acharya Vidyadhar Shukla and Prof. Ravidatta Tripathi, Marathi translation by Vaidya Vijay Shankar Kale, Charak Samhita, Kalpa Sthana, 7/3, Chaukhamba Sanskrit Pratishthan, Delhi, India, Print 2014, Page no. 816 57 Acharya Vidyadhar Shukla and Prof. Ravidatta Tripathi, Marathi translation by Vaidya Vijay Shankar Kale, Charak Samhita, Kalpa Sthana, 12/6, Chaukhamba Sanskrit Pratishthan, Delhi, India, Print 2014, Page no. 839 58 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 251 59 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 721 60 Prof. Krishnachandra Chunekar, Bhava Prakash, Haritakyadi Varga/118, Chuakhamba Bharti Academy, Varanasi, India, Reprint 2013, Page no.56 61 Prof. P.V. Sharma, Dravyaguna-vijnana Vol.2 chaukhamba bharti academy Varanasi,2012 page no 55 62 (Suneeva S Christa,1 Adaveni Swetha,1 Evangeline Christina,1 Rajesh N Ganesh,2 Pragasam Viswanathan 1, Modulatory Effect of Chandraprabha Vati on Antimicrobial Peptides and Inflammatory Markers in Kidneys of Mice With Urinary Tract Infection, Iranian Journal of Kidney Diseases|Volume 7|Number 5|September 2013)

[Find the meaning and references behind the names: Chem, Ayu, Mahesh, Anjana, Blood, Ray, Med, Free, James, Herb]

IRJAY IS THE OFFICIAL JOURNAL OF BALA G PUBLICATION 344 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 VOLUME- 3 | ISSUE- 8 AUGUST 2020 63 (Magneson GR, Puvathingal JM, Ray WJ, Jr. The concentrations of free Mg 2+ and free Zn 2+ in equine blood plasma. J Biol Chem. 1987;262:11140-8.) 64 (Anjana S, Devipriya S, Mahesh CK, James C. Reduction of Bacterial growth in Urine after an Ayurvedic treatment protocol: A case report. J Ayu Herb Med 2018;4(4):147-149)

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