MANAGEMENT OF ANORECTAL DISORDER W.S.R. TO HERBO MINERAL PREPARATION

volume- 2, issue-3(May-June) IRJAY 35 IRJAY, vol- 2, issue-3, May-June:2019; 35-40 Prof. Govind sahay shukl 1 Dr. Manisha Goyal 2 Dr. Rajaram Agarwal 3 1. HOD & Professor, Department of Rasashastra & Bhaishajya kalpana, 2. Assistant professor, Department of Rasashastra & Bhaishajya kalpana, 3. Associate professor, Department of Rasashastra & Bhaishajya kalpana, Dr. S.R.Raj. Ayu. University, Jodhpur ABSTRACT Āyurveda is an age old science of health which emphasize on the health than to cure disease. So, nowadays people are coming back to the nature from synthetics, hence, the Āyurveda will be the future medicinal science of the world, not only the India. In the era of fast food, there is change or irregularity in diet and diet timings and also sedentary life style. In addition to change in diet and life style, one is always under tremendous mental stress. All these causes disturb in digestive system which results into many diseases amongst them ano-rectal disorder constitute an important group. Herbomineral preparations are considered in ayurveda as Rasausadhis which are appreciated for their smaller dosages, quicker effectiveness, long durability etc. Thus the Herbomineral preparations play an important and major role in curing the ailing human beings. Many of these types of preparations are used to treat anorectal diseases like volume- 2, issue-3(May-June) Review Article MANAGEMENT OF ANORECTAL DISORDER W.S.R. TO HERBO- MINERAL PREPARATION Article received on- 27 May Article send to reviewer- 1 June Article send back to author- 3 June Article again received after correction- 8 June Corresponding author- Prof. Govind sahay shukl HOD & Professor, Department of Rasashastra & Bhaishajya kalpana, Dr. S.R.Raj. Ayu. University, Jodhpur

volume- 2, issue-3(May-June) IRJAY 36 IRJAY, vol- 2, issue-3, May-June:2019; 35-40 kasisadi tail, ghrita, arshkuthar rasa, abhayadi modak etc. This article is an attempt to highlight importance and mode of action of the Herbomineral preparations in anorectal disease like piles, fistula, fissure in ano etc. Key words : piles, fistula, Herbo mineral preparation, kasisadi taila, arshkuthar rasa Introduction Ano-rectal disorders are progressively increasing in society. Few important causes are sedentary life style, irregular and inappropriate diet, prolonged sitting and psychological disturbances like anxiety and depression etc. Ano-rectal problems are coupled with psychological manifestations, as all the causes are interrelated to each other. These above mentioned causes result in dearrangement of Jaţharāgni (power of digestion) which leads to Vibandha (constipation) and other associated symptoms. It has been mentioned in ancient classics. Because of all these factor, straining is needed to pass the hard stool, which causes congestion in the network of blood vessels located inside the anal cushions gradually these vessels enlarge and form piles. If the constipation further continues, they become large enough to be called second or third degree piles. These disorders are extremely embarrassing to the patient. Ano-rectal disorders which are commonly seen 1 . fistula-in-ano 2. Fissure-in ano 3. haemorrhoids Management of ano rectal disorders- • Agnikarma, • Raktamokşaņa, • Kşārakarma, • Jalaukāvacārana, • Śaśtrakarma • Bhaişajakarma Among these Bhaişajakarma is an easily palatable by patient which gives relieve to the patient without fear of complication and without producing any untoward effect. QUALITY OF HERBOMINERAL PREPARATIONS Ideal drug should be low in dose and highly effective and easily calm down all doshas . Having quality of easily digestible, palatable, nutritive and cure diseases. It should not produce side effects and nausea also. It contains color, fragment and taste also IMPORTANCE OF HERBOMINERAL PREPARATIONS  The innate qualities of Rasausadhies like quick action, lesser dose, tastelessness, prolonged self-life, and better action are told by rasacharyaas  Our acharyas told that curable diseases easily cured by all medicine but by doing rasachkits a we cure incurable disease also therefore rasachikitsa is the best.

volume- 2, issue-3(May-June) IRJAY 37 IRJAY, vol- 2, issue-3, May-June:2019; 35-40  Properly prepared drug highly effective in low dose and less effective in higher dose by doing samskar addition, separation, duration or time and strategy.  Three types of vaidhyas are told by our acharyas rasa vaidhya, mulikadi vaidhya and shastradi vaidhya . Rasa vaidhya is called bestest vaidhya in all three types of vaidhya. MODE OF ACTION OF HERBOMINERAL DRUGS The therapeutic activity of single drug can be explained by principles of Rasa Panchak . But the mode of action of the compound formulation is not an easy task Poly herbal and herbomineral preparations have 4 basic components in form of Ingredients viz. 1. Activator: -the main ingredients responsible for achieving the required therapeutic activity like loha, tamra,danti, shooran, vanshlochan, suhaga, javakhar, saindhav etc 2. Potentiator: - the drug which can enhance the activity of the formulation like Gomutra, kshar, parad ,gandhak etc . 3. Antidotal: - Either to nullify or to minimize the adverse effect of the drug likes viz. shooran 4. Bioavailability enhancer: - the ingredient which may enhance the bioavailability of the drug in the body like viz Gomutra, trikatu. Here examples of kasisadi taila and arshkuthar rasa are taking for the understanding that how to act herbomineral formulation in ano rectal disorders Table no.1 shows the ingradients of kasisadi taila s .n. Name of the drug Latin name Quantity (gm) 1. Kāsīsa Green vitriol ( FeSo 4 .5 H 2 O) 12 2. Manashila realgar (AS 2 S 2 ) 12 3. Hartal orpiment(AS 2 S 3 ) 12 4. Vidanga Embelia ribes 12 4. Karavira Nerium indicum 12 5. Langali Gloriosa superva 12 6. Saindhava Rock salt 12 7. Pashanbhed Bergenia lingulata 12

volume- 2, issue-3(May-June) IRJAY 38 IRJAY, vol- 2, issue-3, May-June:2019; 35-40 8. Pippali Piper longum 12 9. Citrakmula Plumbego Zeylanica 12 10. Dantimula Baliospermum montanum 12 11. Arka kşira Calotropis Procera 12 12. Snuhi kşira Euphorbia nerifolia 12 13. Swarnakshiri Argimone maxicana 12 13. Tila taila Sesamum indicum 12 14. Gomutra Cow’urine 12 PROBABLE MODE OF ACTION OF KĀSĪSĀDI TAILA Kāsīsādi taila possess Uśņa, Tikśņa, Lekhana, Śothahara and Vatānulomana property Therefore the drug was given as local application in the anal canal gives very good soothing effect during defecation Kāsisādi Taila destroys the Arśa due to working like kşāra without hampering the normal structure of guda. In pharmaceutical point of view Khara Pāka of Kāsīsādi Taila should be prepared because Ācārya Suśruta has mentioned different route of administration of Sneha Pāka in Chikitsā Sthāna as:- Khara Pāka is totally devoid of moisture content Moisture free oil gets absorbed easily through the cells of epidermis. Reduction in size of the haemorrhoids by the local application of Kāsīsādi taila due to its corrosive effect on the wall of affected veins by Lekhana property of contents of Kāsīsādi Taila. The important factors which keep a fissure-in-ano away from normal healing are constant contamination of the wound by feces and frequent friction with the mucosa while there is continuous spasm of the sphincteric muscles. In such situation, a drug which produces a soothing effect, Vraņa Śodhana,Vraņa Ropaņa, Vedanā Sthāpana & Vāta-pittahara action, is more suitable. Kāsīsādi taila having same properties and good soothing effect. It probably removes the accumulated secretions in the fissure bed, promotes healing and reduces secondary infection too. Table no.2 showing the ingredients of arshkuthar rasa s.n. Name of the drug Latin name quantity 1- Shu. Parad purified Mercury 1 part 2- Shu.gandhak purified Sulphur 2 part 3- Loha Bhasma Incinerated iron 2 part

volume- 2, issue-3(May-June) IRJAY 39 IRJAY, vol- 2, issue-3, May-June:2019; 35-40 4- Tamra Bhasma Incinerated copper 2 part 5- Danti Seeds of Baliospermum montanum 1 part 6- Shunthi Rhizome of zingiver officinalis 1 part 7- Maricha Seeds of Piper nigrum 1 part 8- Pippali- Fruit of piper longam 1 part 9- Shooran Amorphophallus campanulatus blume. 5 part 10- Vanshlochan Exudates of bambusa arundunasia 5 part 10- Tankan bhasma Purified Borax 5 part 11- Yava kshara Kshara of Barley 5 part 12- Saindhava lavana Rock salt 5 part 13- Gomutra Cow’urine 32 part 14- Snuhi ksheer Latex of Euphorbia neriifolia 8 part MODE OF ACTION OF ARSH KUTHAR RASA Arsh kuthar rasa balances vitiated vata and kapha dosha . It contains kajjali which is rasayan and potentiates the function of other drugs . tamra bhasma and loha bhasma are work by improving liver functions and vein strengths, danti promote to easing constipation, yava kshara , tankana and gomutra, snuhi ksheer help to shrinking the pile mass and reducing local swelling and inflammation. Important drug of arshkuthar rasa is Suran which is act as a activator of all drugs. Three dravyas of trikatu stimulate jathragni and act as a deepan pachan drug. Thus arshkuthar rasa is functioning very well in the treatment of anorectal disorders. References 1 Acharya agnivesh, charak samhita, uttrardh, kalpa sthan, kashinath shastri, hindi commentary, chaukhambha vishbharti Varanasi, edition 2012, 945, 48-49. 2 Acharya agnivesh 2012, Charak samhita uttrardh, sidhhi sthan, kashinath shastri, hindi commentary, 1021, 5-16. 3 Ayurvedic formulary of india, part-1, 2 nd revised English edition, 2003, govt. of India, ministry of health & family welfare, new delhi. 131, 8/7. 4 Ayurvedic formulary of india, part-1, 2 nd revised English edition, 2003, govt. of India, ministry of health & family welfare, new delhi. 131, 8/7. 5 Ayurvedic formulary of india, part-2, 1 st English edition, 2000, govt. of India, ministry of health & family welfare, New Delhi. 227, 16/2.

volume- 2, issue-3(May-June) IRJAY 40 IRJAY, vol- 2, issue-3, May-June:2019; 35-40 6 Govinddas Sen 2002, Bhaishajya Ratnavali, Hindi Commentary byAmbikadutta Shastri, Chaukhamba Sanskrit Sansthan, Varanasi , 15 th edition, , arsh rogadhikar,111- 112 7 Indradev tripathi 2010, Rasendra sar sangraha, rasvidhyotini tika, hindi commentary, chaukhambha orientalia Varanasi, 2010, 2, 1/4-5. 8 Indradev tripathi 2010, Rasendra sar sangraha, rasvidhyotini tika, hindi commentary, , chaukhambha orientalia Varanasi, 219, 2/5-7 9 Lakshmipati shastri 2012,Yoga Ratnakar – Hindi Commentory, Edited by Brahmashankara Shastri, Chaukhambha Samskrita Samsthana, Varansi., arsh-chikitsa, 265. 10 Rasapaddhati, acharya Bindu, siddhiprada hindi commentary by dr.siddhinandan mishra, chaukhambha orientalia Varanasi, edition 2016, pg.no.3. 11 Sharangdhar Samhita 2005, pandit sharangdhar acharya, commentary of adhamalla’s dipika and kasharam’s gudarth deepika, chaukhambha orientalia Varanasi, 226, 142- 145.

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