Significance of Zones of inhibition
Zones of inhibition refer to the clear areas surrounding an antimicrobial agent on an agar plate where bacterial growth has been prevented. This phenomenon is measured in millimeters and serves as an indicator of the effectiveness of various antimicrobial agents, including antibiotics and antifungal substances. These zones are critical in microbial testing to determine the efficacy of specific compounds against bacteria or fungi, providing essential data for assessing antimicrobial activity and susceptibility in scientific studies.
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The concept of Zones of inhibition in scientific sources
Zones of inhibition measure antimicrobial effectiveness, represented by the diameter around agar wells where bacteria cannot grow. This concept is pivotal in disc diffusion assays, showcasing the antibacterial efficacy of substances tested.
From: The Malaysian Journal of Medical Sciences
(1) These are areas around the antibiotic discs where bacterial growth is inhibited, and their diameter is measured to determine susceptibility.[1] (2) Areas surrounding the wells on the agar plates where fungal growth is prevented by the activity of the antifungal agents; used to measure susceptibility.[2]